Ethoricoxib and its structural analogues( Excineas, Arkoksia) are the last representatives from the category of non-steroidal anti-inflammatory drugs.
The drug is characterized as an anti-inflammatory and analgesic substance that can alleviate the condition and improve the quality of life in chronic and acute joint pain caused by ankylosing spondylitis, rheumatoid arthritis, acute gouty arthritis and some other diseases of the OA.
Contents of the article
- Ingredients
- Ingredients
- Pharmacological profile
- Indications and contraindications for use
- Dosage and dosage regimen
- Special patient groups
- Overdose and adverse reactions
- Special instructions
- Interaction with other drugs
- Practical experience with
- Overview from doctor
- Opinionpatients
- Pros and cons
- Purchase and storage of the preparation
Ingredients
Ingredients:
- active ingredient ethoricksib;
- vitamin and mineral supplements.
Produced in the form of tablets, which are covered with a special coating, in size from 0.06 to 0.12 grams.
Features of substance
Etorikoksib is a specially developed synthetic substance belonging to the group of coxibs, it is a representative of non-steroidal anti-inflammatory drugs. It is used exclusively orally. This drug comes from the United States of America, and it was invented in a private laboratory "Merck &Co. "
This substance and all preparations on its basis stop the painful attack 20-25 minutes after taking. A minimum dosage is sufficient to achieve an analgesic effect that is long in a day.
Few people know, but although the drug is registered in 76 countries and was developed specifically in the US, it is not allowed to be used in this country.
Pharmacological profile
Etorikoksib belongs to the class of NSAIDs and is used for increasing the pain threshold and the occurrence of an inflammatory process due to 
exacerbation of vascular diseases and disorders of the motor support apparatus.
This drug is a synthetic medical product and has an anti-inflammatory and analgesic effect on the entire body for half an hour.
The drug is well absorbed by the body and is quickly excreted along with urine. Its effect on the body is due to the selective mechanism of inhibition of COX-2, has no effect on COX-1, due to which it is able to prevent the further development of the inflammatory process.
As for the analgesic effect, it was achieved by increasing the production of a substance such as bradykinin, which reduces inflammation and irritation of blood vessels.
Despite its rather active effect, the drug does not disrupt the work of platelets and does not irritate the intestinal mucosa, which makes the reception of Etoricoxib completely safe.
The main pharmacokinetic feature of the substance is a decrease in the degree of disturbances in the functioning of blood vessels, improvement of blood flow, activation of production in the required number of leukocytes and blocking the inflammatory process.
This substance also has antipyretic effect on the body, which can be observed with a strong inflammation of the connective tissues.
Getting into the body, the drug for half an hour has an anti-inflammatory and analgesic effect on the body, is derived naturally.
How NSAIDs work and coxibes
Indications and contraindications for use
Etorikoksib is recommended to be taken at the following indications:
- inflammation of connective tissues;
- removal of pain and discomfort with active development of arthritis, inflammation of joints and osteochondrosis;
- therapy for gouty and rheumatoid arthritis;
- treatment of ankylosing spondylitis;
- of osteoarthritis.
The main feature of the drug - this is a small list of contraindications. The only case when the medication is not recommended for use is an individual intolerance of the active substance.
Therefore, before taking the medicine, you need to consult a doctor and take a test for allergens.
Dosage and dosage regimen
The drug is used exclusively inward, by oral route, after a meal, and the recommended dosage depends on the type of the disease, its progress and the recommendations of the treating doctor. But as a rule, it does not exceed 1-2 tablets( 60-120 mg) per day, which are taken in the morning and evening after eating.
If chronic osteochondrosis is observed, the dosage increases and can be 2-3 tablets( approximately 120-180 milligrams per knock).
Special groups of patients
Medication is strictly not recommended during pregnancy and during the whole period of breastfeeding, as this can adversely affect the development of the fetus and disrupt the production of milk from the mother.
For children, treatment with Etoricoxib is contraindicated because taking this medication at this age can cause serious health problems due to the unpreparedness of the young organism for taking such medications.
Therefore, it is recommended to select individually a drug similar in effect to the body, but with a less aggressive active substance.
Overdose and Adverse Reactions
If the patient has taken more than 60 milligrams of the drug at a time, this can cause overdose symptoms, which can lead to a disruption in the functioning of the heart, the liver. Vascular dystonia is also possible.
In order to get rid of the effects of an overdose and do not damage your health, you should immediately contact your doctor for the necessary medical care.
The patient is made a dropper and gastric lavage is carried out for the fastest withdrawal of the medicine from the body.
Some patients may experience the following side effects when taking medication:
- is an allergic reaction to substances in the formulation;
- mild dizziness, general malaise, which can be caused by an active analgesic process;
- swelling of the extremities on which inflammation is observed;
- may also have vomiting and loose stools, a rare flatulence.
Special instructions
Medicinal substance Etoricoxib is not compatible with the intake of alcoholic beverages, since this combination can cause an allergic reaction and poisoning of the digestive system.
If a patient has impaired renal and hepatic function, the medication is permitted, but under the supervision of a physician.
Interaction with other
medications As practice shows, the medication is often and successfully used in combination with other medicines during treatment therapy( below is a list of compatible drugs):
- Warfarin , designed to stabilize the process of blood clotting;
- Acetylsalicylic acid , which is used to treat and prevent vascular diseases.
- Norethindrone and Ethinyl estradiol are contraceptives for oral women.
Practical experience with
The review of the doctor, patient feedback, the analysis of the pros and cons of the drug Etoricoxib, as well as its analogues, will be useful to those people who still have doubts about this remedy.
Overview from a doctor
Etorikoksib is a new medical preparation, belongs to the last generation of NSAIDs, the action of the drug is directed to an anesthetic and anti-inflammatory effect.
The main advantage of the medication is a unique composition that does not harm the health and does no harm to the pancreatic shell.
Evgenia Larina, rheumatologist
Opinion of patients
The doctor rheumatologist complained to me about this medication after I started having problems with joints due to heavy physical work. After the first course of treatment, I felt a significant improvement, swelling and inflammation were gone.
Nikolay Polnov
I got acquainted with tablets of Arkoxia, when swelling in the knee joints and inflammatory processes began, accompanied by an increase in the pain threshold.
Referring to a doctor, he recommended me this medicine, because today it has the most effective effect on the body and least harm to health.
I was prescribed 3 courses and already at the beginning of the second I felt a great relief. To date, the course of treatment continues.
Alina Karlova
Most patients recommend not taking the medicine before driving or before doing any other activities that require attention and concentration, since the drug can cause a slight drowsiness.
Pros and Cons of
Pros: 
- natural composition;
- a small list of side effects and contraindications;
- wide range of applications.
Cons:
- individual intolerance to the formulation;
- is prohibited during pregnancy and lactation.
Purchase and storage of the preparation
Form release - tablets in a special shell with a special protective film.
The price of all analogues based on etorikoksib lies in the region of 600-800 rubles.
Store the medicine in a dark place and out of reach of children at a temperature of no higher than 20 degrees Celsius for half a year.
It is released solely by prescription.
