Any manifestation of the pain effect causes discomfort, dramatically worsening the general condition of the body.
Special spread recently, using the disease of joints and bone tissue, causing deformation of the human skeleton.
Most often, Paget's bone disease affects men, at the age of 40 years, earlier manifestations are of a very rare nature.
Contents of the article
- History of the appearance of
- Causes and symptoms of the disease
- What are the manifestations of pathology?
- Diagnosis of the disease
- Complications of exacerbation of the disease
- Supportive therapy
- Detection actions
- Preventative procedures
History of the appearance of
Bone tissue, throughout the life of a person, is subject to constant changes. Some cells destroy tissues, others repair them.
This process is of a natural nature, and is called remodeling. However, in some cases, a failure occurs, the smooth functioning of the cells is broken, and as a result, a new formation of tissues appears on some parts of the bone.
For the first time, a similar kind of deformation of bones and joints was described in the late 19th century, by a surgeon from England, James Paget.
It was he who put forward the hypothesis that the cause of the disease is a viral infection, which during the aging process can cause an inflammatory process of bone tissue.
Although the theory of a well-known surgeon of past times, to date has not been thoroughly confirmed, such violations in medical practice are commonly called Paget's disease.
Causes and symptoms of the disease
The causes of deforming osteitis( the medical name of the disease) have not been fully revealed to this day.
In most, the most common opinion about the appearance of bone formations, consider a slow infection of a viral nature.
In connection with this factor, relatives whose family is diagnosed with the disease, it is recommended to take an annual blood test every year. If necessary, once every 2 years, you should do a radiograph of the skeleton, for a complete sense of security.
What are the manifestations of pathology?
Symptoms that help determine Paget's disease in the initial stage are absent.
It happens that deforming osteitis can occur without manifestation for several years, however, as the disease develops, the symptoms begin to appear more distinctly:
- Aching permanent pain in the bones located near the joints. Especially it increases during the night sleep or rest.
- Joint pain, causing limitation of motor functions.
- Visible deformation of joints and bone tissue in the form of dense thickenings.
- Inflammation and rise in temperature in the source of the disease.
The process of the disease, weakens the bone tissue, making it more prone to fractures, even with minor injuries.
Appears stoop, joints become compacted and curvatures are formed. As a result of long-term studies, experts have found that within 1 year, 1 cm tissue is damaged.
Diagnosis of the disease
Diagnosis of the disease involves a complete radiographic examination, as well as a biochemical blood test for calcium, phosphorus and magnesium.
On the photo of MRI of bones in Paget's disease
The level of alkaline phosphatase, determined by the laboratory, in the presence of the disease is much higher than normal. Another method that determines the location of deforming osteitis is scintigraphy.
The procedure helps to ensure the visualization of the skeleton as a whole.
By means of radiography, specialists determine the presence of Paget's bone disease by the following factors:
- narrowing of the joints in the lower limbs;
- deformation of individual vertebrae, in the form of an increase in size and curvature;
- abundant thickening of the bones of the skull with a blurred outline of the outer plate;
- on the areas of bone tissue visible obvious seals.
Complications of exacerbation of the disease
The course of the disease can last for a long time, besides the main symptoms, which many people try to ignore, there is a possibility of complications.
One of the most common complications, with Paget's disease, is the jamming of nerve endings and vessels. The increase in bone takes more space around the important arteries and nerves, thus leaving them no room for full-fledged work.
In the case of a pinched nerve or blood vessel, there may be a loss of sensitivity, in the vicinity of the lesion.
Increased bone mass, requires additional blood volume, this causes the heart muscles to increase the number of cuts.
Thus, there is an overload of the heart, eventually leading to heart failure. One of the rare, but the most serious complications, doctors call - malignization, the cause of the appearance of the sarcoma. The formation of diseased tissues is rapid, causing severe pain.
In this case, seals can form metastases that affect new areas of bones, joints, and lungs.
The removal of part of the vertebra is called a laminectomy of the spine. After the operation, patients notice a significant improvement and no pain.
Among the anomalies in the structure of the spine, there is one that stands out - the lumbarization of S1.What is the essence of the anomaly and what steps should be taken when pathology is detected?
Supportive therapy
Unfortunately, a complete cure for Paget's disease is impossible. By prolonged medical treatment, it is possible to provide a significant reduction in the disease, as well as to halt the development of tumors.
Orthopedics deal with the diagnosis and treatment of this type of ailment. The treatment process is a long course, reaching, depending on the complexity of the disease, up to 6 months.
To slow down the process of joint deformation, specialists designate a group of drugs called bisphosphonates .
The administration of drugs should be done only by a narrow specialist leading the patient. A group of recommended drugs can cause a number of side effects that can lead to negative consequences.
As an anesthetic, orthopedic specialists recommend the use of nonsteroidal drugs that provide anti-inflammatory action. Also, when joint disease is prescribed, calcium and vitamin D. are prescribed.
Actions for detecting
disease. It should be noted the insidiousness of Paget's disease, the course of the disease can be completely undetectable for a long time, not to cause discomfort.
Timely solution of the problem, will help prevent negative consequences.
In the early stages of the disease, specialist intervention will relieve the patient of complications. In this case, the treatment will be successful.
The only condition, with a positive outcome, is a regular visit to the attending physician.
Do not forget about the periodic analysis of blood, for serum alkaline phosphatosis.
Preventative techniques
Paget's disease, with no special reason for occurrence, can form in every person. However, adherence to preventive measures will significantly reduce the risk of joint disease. 
The basics of measures for the prevention of deforming osteitis are as follows:
- to avoid injuries to joints and bones whenever possible;
- at the first signs of joint diseases, immediate reference to a specialist;
- complete and timely treatment of all types of viral, infectious diseases;
- adherence to all doctor's recommendations when prescribing treatment.
It should not be forgotten that excellent health and persistent immunity to various diseases can be obtained only by maintaining the right way of life.
Full nutrition, rich in vitamins, minerals, calcium and phosphorus, as well as regular walks in the fresh air, simple sports exercises, fill the body with a healthy spirit, lightness and cheerfulness.
