2 Rules for the preparation for the analysis
Amylase is released at different times and in different conditions, including its consistency varies throughout the day repeatedly. In this regard, when passing tests for amylase a person must comply with several rules:
- Analysis must be taken on an empty stomach and in the morning.
- The enzyme content in the samples is determined within the first hour after it is taken. After a while, the enzyme breaks down, and analysis is impossible.
- If the laboratory can not analyze the enzyme level in urine for 1 hour, urine freezes.
- It is forbidden to drink alcohol before taking the test, at least 24 hours before it.
- Before taking the test, do not take diuretic drugs for 2 days.
- Do not take hot and salty foods 24 hours before taking the test. Also, you should not eat foods that stain urine in an unnatural color - carrots, beets, tomato paste.
- 24 hours before the test, physical activity should be avoided.
- You can not be in a state of stress and nervous strain 24 hours before taking the test. If you do not calm down, then it is better to postpone the analysis for another day.
- The content of amylase in urine can be influenced by the presence in the body of the following drugs - pentazocine, cholinergic agents, corticosteroids, birth control pills. In this regard, for the period of the analysis, the patient being treated with these substances is canceled.
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If one or more of the requirements can not be met, then the analysis for amylase will be erroneous and, accordingly, the treatment will be assigned incorrectly. In this regard, if the conditions for submitting the analysis can not be met, you should transfer this procedure until the moment it is possible.
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Urine analysis for amylase is done at any time of the day only if the patient is taken to hospital in serious condition and there is a threat of his life, as pancreatitis is accompanied by severe pain. But even in this case the doctor knows what the norm of amylase in the urine should be at a given time and in a similar state.
In addition to pancreatitis, there are a number of other diseases identified by the violation of the norm of amylase in the urine:
- , an oncological disease that affects the pancreas;
- closure of the pancreatic duct;
- inflammation or rupture of the appendix;
- perforation of the stomach;
- ketoacidosis on a background of diabetes mellitus;
- dysfunction of salivary gland caused by any disease of this system, for example paratitis;
- operative treatment of an organ located in the abdominal cavity;
- acute inflammation of the gallbladder;
- colitis - small bowel obstruction;
- ectopic pregnancy;
- impaired kidney function;
- liver disease;
- receiving a large amount of alcohol or a small amount of low-quality alcohol made from methyl alcohol.
Amylase can be increased or decreased not only in pathological processes in the body, it is also observed in pregnant women and in people undergoing treatment with Furosemide, Ibuprofen or narcotic analgesics.
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Amylase does not increase its level when forming in the pancreas dangerous cysts and neoplasms, but only if the tumor is not joined by an infection. Usually, the data of the formation are detected and diagnosed by ultrasound examination of the pancreas or computed tomography.
1 The essence of the issue
The level of amylase in the urine is diagnosed mainly in the disease of the pancreas. In the human body, it is isolated by the pancreas, is about 40%, the remaining 60% - is an amylase, salivary glands. In this regard, to determine the acute inflammation of the pancreas by its level can be with extreme accuracy, if you know the norms of the enzyme content in the urine of a healthy person.
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However, it should be borne in mind that the content and activity of amylase in the body at different times of the day are different,time its activity is significantly reduced. This should be understood by lovers of overnight snacks. This habit can lead to pancreatitis or gastritis. After all, without sufficient amylase carbohydrates are not split, pieces of food for a long time lie in the stomach undigested, stomach acid and bile at night not quite the right consistency. All this sooner or later leads to disruption of the gastrointestinal tract, and even to the ulcer of the stomach or duodenum.
3 The need for the
study Knowing which diseases can cause a change in the level of amylase in the urine, the analysis is prescribed in cases where the patient has manifestations of such diseases. Symptoms include:
- Severe abdominal pain right under the sternum, eventually becoming a girdle. Pain covers the patient's body approximately at the level of the lower ribs.
- The patient's body temperature rises.
- Appetite completely disappears.
- Appears nausea and vomiting.
These symptoms are inherent in inflammation of the pancreas, but other manifestations are also less significant. Then the analysis is appointed at the discretion of the doctor, based on his experience.
4 What is the norm?
The content of amylase in the blood and in the urine is different, in the urine the enzyme is in a more concentrated state, because the urine in the body is much less than the blood. In it, the amylase is in a dilute state. In connection with this, amylase in the urine is called diastase and has its own norms for a healthy organism;
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- in U / l - up to 1000;
- in μcal / l is 28-100.
- in units of measurement systems is less than 650 U / l.
The doctor should remember that, despite the very specific figures of amylase in the urine, the norm is regulated in the body not only by the presence of pathology, increased or decreased level of the enzyme may be the individual state of the body.
- 1 The essence of the matter
- 2 Rules for preparing for the
- 3 analysis The need for the
- 4 study What is considered the norm?
What is urine amylase? First you need to find out what kind of enzyme it is and why it is needed. Amylase is secreted mainly by the pancreas, but recent research has shown that this enzyme is also released in the liver, kidneys, lungs, adipose tissue and the small intestine.
Amylase cleaves complex carbohydrates to simple sugars. This is done to ensure that these substances are in the blood, since initially they are too large to absorb into it. A split with the help of amylase to small molecules, the so-called mono molecules, sugar easily enters the capillaries of the villi of the intestine and from there through the large veins to the liver and other organs. Glucose is necessary for the body to generate energy, and amylase provides this process. And in the liver, almost half of the total glucose in the body falls.
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Amylase may have different activities, for example, the enzyme that is released in the pancreas can easily convert starch from raw potatoes to glucose, and the one that is secreted by the salivary gland can barely cope with a piece of bread in the mouth.
