Codelac Neo. Instructions for use of syrup, tablets, drops for children. Price, analogues, reviews

Codelac Neo - a drug for cough high efficiency. Instructions for use contains information about its bronchodilator, expectorant and relieves inflammation properties. Admission to the strict adherence to the recommended dosage to quickly facilitate the patient's condition.

Shape and composition of the drug release

The drug is available in several dosage forms:

• Tablets with sustained release of active substance, 10, 20, 30 or 50 pieces. of cellular in blisters or in plastic jars;
• Drops for internal administration, 20 ml of liquid without color with vanilla flavor in a glass bottle with a dropper pack carton;
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• syrup, thick liquid without color with vanilla odor, 100 or 200 ml glass jars dark color with a spoon for dispensing.

Tinted glass provides content protection from sunlight during the whole shelf life. The structure includes a number of active agents and auxiliary substances.

The drug substance - butamirata citrate:

• pills - 50 mg per 1 piece;
• drops - 100 mg in 20 ml;
• syrup - 7.5 mg in 5 ml.

Additional material:

• pills - Lactose 0.241 g, hypromellose 0.085 g talc 0.004 g magnesium stearate 0.004 g silicon dioxide 0.006 g, Povidone 5 mg;
• drops - Sorbitol 8.1 g, glycerol 5.8 g, 96% ethanol, 60 mg, 23 mg saccharin, benzoic acid 23 mg, 23 mg vanilla flavor, sodium hydroxide 30% solution of 10 mg of pure water to 20 ml;
• syrup - Sorbitol 2.025 g, glycerol 1.45 g 96% ethyl alcohol 12.5 mg, 3 mg saccharin, benzoic-ta 5.75 mg, 3 mg vanilla flavoring, sodium hydroxide 30% - 1.55 mg Sterile water to 5 ml.

Auxiliary components give the required properties of each dosage form and provide the completeness of absorption of the active substance. sodium butamirata represents white crystals, readily soluble in water. The substance acts by analogy with codeine, which now can be bought only in the presence of a strict prescription form number 107-1 / y.

These forms are only qualified professionals of various medical professions. For presentation to the pharmacy to buy drugs strongest form must be completed in Latin and contain the name of the product and its composition. Also necessarily required number of stamps and medical registry of medical institutions.

Earlier in the sale of relatively great popularity drug Codelac codeine-based. With the adoption of the law on seizure of drugs with codeine from a free vacation new Codelac now contains less active ingredients and different prefix in the name Neo, that is new.

pharmacological properties

Codelac Neo instruction manual recommends for eliminating coughing by direct effect on the area in the brain, which is responsible for the appearance of cough. The drug reduces the cough exhibits expectorant effect, expands the bronchi, reduces inflammation, reduces the resistance of the pulmonary system and increases the degree of blood oxygen saturation.

Cough occurs as a result of activation of the innate reflex, which is required to remove foreign particles, mucus, necrotic tissues and fragments of bronchial microorganisms. Cough signal generated in the medulla oblongata. Receptors that are affected by the signal, located mainly on the back wall of the trachea and throat, as well as in an area where the trachea is divided by 2 bronchus.

During stimulation of these sensitive areas of the signal to the brain. The cough begins as the response.

Depending on the frequency and degree of irritation attacks may be different in strength and duration of cough. The momentum sent the medulla oblongata, it reaches the diaphragm and intercostal muscles and stimulates their sharp cuts. During certain cough glottis closes. Then, after the contents of the bronchi muscle tension with a force thrown out.

Butamirata citrate blocks reciprocal phase from the medulla oblongata. Due to this it is possible to completely get rid of even heavy, deep and debilitating bouts of coughing.

Pharmacodynamics and Pharmacokinetics

Absorption: immediately after receiving the internal bumamirata kotorkogo citrate for a period of time without residue digested in the gut. Upon receiving the highest concentration of 0.15 g of the active metabolite in the blood observed after 90 minutes, reaching 6.4 mg / mL.

Distribution and biotransformation: butamirata undergoes extensive conversion to the preparation of 2-phenylbutyric acid and diethylamino-ethoxyethanol directly in blood plasma. These compounds also have an effect against coughing and up to 95% bind to plasma proteins, allowing them subsequently occurs long excretion.

On further admission accumulation does not occur. Excretion: The half-life time of about 6 hours. The main part of the display memory.

Indications

Dry cough of different origin, including appearing in whooping cough. The drug suppresses the optimum reflex before and after surgery and for the study of the bronchi.

Bronchoscopic lung special device is introduced in the form of a rod with controlled elastic bending at the end. Due to the specificity of cough is absolutely contraindicated. Therefore, it should be completely suppressed in advance.

After the operations side effect as dry hacking cough and appears as a result of the residual effect of the preparations for administration to man in the state of anesthesia.

But for the normal accretion of damaged tissue they do not have any high loads for the following reasons:

• during cough abdominal wall muscles are too tense, and do internal organs with fresh stitches experience intense shake;
• it can lead to a divergence of seams and the need for re-intervention of emergency.

Therefore, even in the absence of any manifestations of a dry or wet cough after the operation it is recommended prophylactic antitussives. Codelac Neo relates to one of the best drugs for cough of any etiology.

One of the readings - whooping cough. This disease is characterized by the free distribution and reproduction of microorganisms exclusively within the human body. It refers to dangerous diseases. A special risk is for children under the age of 2 years.

Contraindications

Codelac Neo is banned for use in the treatment of cough in children aged less than 3 years, in the I trimester of life gestation, lactation period and at a high sensitivity to substances forming part of the means. In II and III trimesters of use is possible, if the benefit to the woman above the potential harm to the fetus.

Studies on the effect of butamirata on the unborn child during the first 12 weeks of pregnancy have not been conducted, so to avoid the negative effects it is recommended to resort to drugs cough treatment with proven security. Studies in animals have not shown any adverse effects on the offspring. Therefore Codelac Neo conventionally considered safe for the fetus.

Strict limitation for use in the I trimester due to the fact that during this period, the risk of harm to the child's development is greatest. At the beginning of pregnancy is the formation of all major systems and organs of the fetus. And even insignificant exposure can lead to the formation of defects and deformities.

At what age can use the drug

Codelac Neo instruction manual recommends not to apply for the following age categories:

• drops - infant age less than 60 days;
• syrup - Children's age less than 3 years;
• pills - less than 12 years.

Butamirata citrate has an effect on the particular responsibility of the nervous system. It is composed of components that can cause extensive allergic reaction. For withdrawal symptoms in such cases requires immediate hospitalization, intravenous infusion of drug solutions and receiving powerful adsorbents.

To implement the whole scheme, in practice it is very difficult not only for children but also for the mother. Therefore it is not worth the risk and try, without a doctor's prescription to treat yourself a little kid. At this age, only mild disease can be treated at home with his mother full of confidence in their own competence in the selection of drugs.

Instructions for use for children, the dosage of the drug

Codelac Neo recommended for children, available in liquid form drops or syrup. Instructions for use of certain recommended doses and regimens depending on the age group of the patient and the dosage form of the drug. If necessary, they can be exchanged for each other in view of age of the patient and the revision recommended for single dose amounts.

Pills

Codelac Neo instructions for use restricts reception to persons under 18 years of age. Disinfection tablets should be considered individually by the attending physician depending on the severity of symptoms and indications. Tablet form taken orally without prior grinding.

The shell is designed to dissolve in the intestine provided weakly alkaline medium.

The main function of gastric juice - is digesting food, for medicine - a change in the chemical structure. The release of active substance in the stomach will lead to their breakdown and further to the absence of therapeutic action. Therefore, coated tablets, divide and crack before swallowing unacceptable.

More acidic environment in the stomach prevents premature release of the active substance, thus avoiding its destruction to the digestive tract hit. Absorption of drugs occurs in the small intestine. To facilitate the penetration process in vascular network tablets composed of compacted fine powder.

This provides a high contact area of ​​the active substance with the walls of the intestinal tract. Tablets Codelac Neo different modified release, at which the layer-dissolution and a longer therapeutic effect.

This is achieved by suction of small portions of the dose over a long time. The modified tablet structure maintains the concentration of therapeutic agent at a constant level between individual doses tablets.

Drops

Drops are used to treat children under the age of 2 months.

Regimens and dosages:

• 2-12 months - 10 pieces of 4 times a day;
• 1-3 years - 15 pieces of 4 times a day;
• 3 years - 25 pieces of 4 times a day.

Drops rapidly and completely absorbed after oral administration. This provides a rapid onset of therapeutic effect, and soon after the start of drops there is a significant relief of the patient. The half-life drops of 6 hours. exchange metabolites are mainly excreted by the kidneys.

Before using in children younger than 2 years, it is desirable to consult a pediatrician watching. If cough persists for more than 5 days, the question of further admission should be addressed to the expert. He will be able to evaluate the appropriateness of treatment with the same drug and the need for the appointment of additional drugs for a faster recovery.

Syrup

Codelac Neo instruction manual recommends taking before eating, drinking clean, cool water.

Dosage and number of administrations per day:

• 3-6 years - 5 ml 3 times;
• 6-12 years - 10 ml 3 times;
• over 12 years - 15 ml 3 times.

dimensional device included in the kit should be used for accurate dosing. You need to pour the syrup level mark achieve without excessive influx of the drug solution.

Side effects

From the central NA may have dizziness, disappearing after the completion of treatment or daily dosage correction. On the part of digestion - diarrhea, nausea, various degrees of severity.

In severe digestive functions recommended a temporary transition to solid foods containing no excessive amounts of dietary fiber. For food protein products should be chosen in boiled or stewed in combination with cereals, potatoes and other products made from flour.

Overdose

When a substantial excess of the recommended dose may cause vomiting, dizziness, nausea, feeling, drop in blood pressure and disturbance of spatial coordination.

For the treatment should take laxatives salts based on, adsorbents or additional drugs according to the symptoms.

special instructions

As Codelac Neo sweetener comprises sodium saccharin and sorbitol, therefore it is approved for treatment of patients suffering from diabetes. For the active ingredient is present the risk of drug dependence.

The drug should be used with caution in people with diseases of the liver system, prone to alcoholism, epilepsy patients and in patients with brain dysfunction.

During treatment, it is recommended to refrain from traffic control and other activities that require high reaction rates and increased attention due to the risk of intense dizziness.

drug interactions

No drug incompatibility described for preparation Codelac Neo. During treatment should avoid drinking alcohol and taking other drugs that have a depressing effect on the central nervous system - sedatives, hypnotics, neuroleptics and tranquilizers.

For the reason that butamirata actively inhibits the function of the cough center, it is prohibited to combine the reception Codelac Neo with other anti-cough, which actively stimulate mucus formation. Ignoring this condition can lead to the accumulation of liquid contents into the lungs, the development of bronchial spasm and the spread of infection in the lower parts of the lung tissue.

analogs

If necessary Codelac Neo be replaced with other drugs with the same substance. They differ manufacturers, prices, concentration and composition auxiliary components.

highlighted some of the most common:

• Sinekod - the best known analogue with a higher cost per vial. It is produced in the form of drops 20 mL, syrups 100 and 200 ml. It contains similar concentration of active ingredient. It does not tablet form.
  
• Omnitus - commercially introduced in the form of tablets of 20 mg or 50 mg of 10 pieces in a package in the form of a syrup with a content of active substance butamirata 0.8 mg in 1 ml. 1 bottle containing 200 ml of the syrup and packed in a cardboard box, together with instructions for use and the metering device. It has a more affordable price.
• Panatus - the drug is released in the form of tablets of 20 mg of 10 pieces in a package in the form of a syrup with a content of Forte 7.5 mg of active ingredient per 5 ml. 1 bottle of 200 ml with a dosing spoon and the instruction is placed in the carton.

All analogues operate with substantially equal efficiency and can easily replace each other even during the treatment.

Terms, conditions of sale and storage

Codelac Neo released from pharmacies without a prescription from a specialist. expiration dates do not depend on the form of the release of the drug and up to 5 years after the date of production. After the expiry of receiving funds is prohibited. standard storage conditions - at a temperature of ambient to 25 ° C with no direct sunlight.

Keep refrigerated undesirable since excessively low temperature will lead to an increase in density of the syrup and difficulties with accurate dosing. Pills and drops can be stored in the cold without a loss of therapeutic agents, if it is convenient to the consumer.

Price in drugstores of Moscow, St. Petersburg, regions

The minimum price in the region of 150 rubles. per 100 ml. In Moscow, prices start from 170 rubles. a bottle of similar volume. In St. Petersburg, the price is slightly lower - from 160 rubles. The maximum price you can find the major networks in the central pharmacies.

Thus, the prices are quite reasonable, when you consider what a relief to bring the drug to a human patient suffering from dry cough. And in the postoperative period, all patients should avoid any loads for a quick and complete healing of sutures.

Codelac Neo - a worthy preparation for the suppression of cough in many cases life. Use according to the instructions will quickly normalize the state without taking powerful and often dangerous drugs.

Registration of the article: Lozinski Oleg

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