Sanorin nasal drops. Price, instructions for use, where to buy for children, reviews

The drug Sanorin belongs to the category of topical vasoconstrictor drugs. Nasal drops are used for the symptomatic treatment of diseases of the ENT organs, accompanied by the secretion of mucus. The drug has an affordable price and a high safety profile.

Release form and composition of the drug

The otolaryngological solution is produced in the form of a transparent liquid of medium viscosity. The drug is supplied to pharmacies in sterile vials made of medical darkened glass.

The material is environmentally friendly, chemically neutral and has hypoallergenic properties. The volume of the bottle is 10 ml. It is equipped with a drop dispenser with 1st opening control. Each vial with a medicinal composition is packed in a solid cardboard box.

The main pharmacologically active substance of Sanorin is naphazoline nitrate. This chemical compound of a complex molecular structure provides a reduction in pathological exudation and elimination of edema of organ tissues. The concentration of the active ingredient is 0.1 or 0.05%. Naphazoline nitrate has a short biochemical action period.

Sanorin - nasal drops, the price of which is available to a wide range of potential consumers. The drug is actively used in modern otolaryngological practice.

Auxiliary components of the medicinal solution:

Chemical compound	Properties and action
Orthoboric acid	Monobasic chemical compound with weak acidic properties. Has a disinfecting effect and antiseptic properties. Binds free neutrons, deactivating chemically aggressive and toxic substances.
Ethylenediamine	An amine organic compound involved in chemical synthesis and condensation reactions. Possesses fungicidal properties, is active against fungal pathogens.
Paraben	Food additive E218. Belongs to the category of esters. Possesses preservative properties, prolongs the shelf life of medicinal formulations. It has an antiseptic and fungicidal effect.
Distilled water	A natural solvent for the pharmacologically active components of Sanorin. Gives nasal drops a liquid consistency.

The drug has a balanced chemical formula. It is effective in treating colds with characteristic symptoms. Sanorin significantly facilitates nasal breathing by reducing the volume of exudate secreted.

Pharmacological properties

The medicinal solution narrows the peripheral vessels and small capillaries of the organ, relieves pathological edema, which develops as a result of the immune response to viral-bacterial invasion.

The pharmacological properties of Sanorin are based on the ability of naphazoline nitrate to quickly stop the manifestations of the common cold, eliminate nasal congestion, remove pathological exudate from the epithelial (mucous) wall covering organ.

The drug expands the ducts of the Eustachian cavities, facilitating and accelerating the outflow of mucus. It eliminates the inflammatory process in the paranasal sinuses, which is characteristic of colds of viral and bacterial genesis.

In the area of ​​instillation, naphazoline nitrate expands the bloodstream, lowering pressure and facilitating respiratory activity. Antiseptic components of the medicinal composition suppress pathogenic microorganisms in parallel.

A tangible therapeutic effect is achieved within 5 minutes. after instillation and lasts 4-6 hours. The drug reduces blood flow to the venous sinuses, eliminates exudation of the mucous membranes in the area of ​​application.

An additional bonus is a decrease in lacrimation, which is characteristic of seasonal colds and inflammation in the nasal cavity. The drug is intended for local use and belongs to the pharmacological category of symptomimetics - agents for suppressing the clinical manifestations of diseases.

Pharmacodynamics and pharmacokinetics

Naphazoline nitrate is a short-acting alpha-adrenergic agonist. It stimulates the protective functions of the epithelial coating. The chemical compound excites the nerve processes of the walls of the nasal cavity and causes vasoconstriction (narrowing of the lumen of the bloodstream) of adrenergic receptors.

Sanorin - nasal drops, the price of which is low, in contrast to the therapeutic properties of the drug. The hormone-responsive adrenaline and norepinephrine receptors are physiological elements that perform an important function in the structure of the sympathetic nervous system.

Intranasal delivery of Sanorin in a drip method provides a pronounced, fast and long-lasting vasoconstrictor effect. The action of the pharmacologically active components of the drug is not limited to the paranasal sinuses, Eustachian tubes and the mucous membrane of the respiratory organ.

The therapeutic effect of the use of Sanorin extends to the entire nasopharyngeal cavity, affecting the visual apparatus.

Medicine:

• eliminates hyperemia;
• reduces the pathological activity of the lacrimal glands;
• increases the patency of the upper respiratory tract;
• relieves the nasopharyngeal tissue from excess exudate, and the cavity from barrier mucus that impedes respiration.

Resorption of Sanorin when applied topically is not observed. Insignificant absorption into the systemic circulation is leveled by the hepatic enzyme monoamine oxidase, which is responsible for amine catabolism.

The compound carries out oxidative deamination of the pharmacologically active components of the nasal drops. Therefore, a change in the blood formula and an increase in the concentration of naphazoline nitrate in serum are not observed.

Indications for use

Sanorin is prescribed for colds of the upper respiratory tract associated with intensive production of mucous secretions and swelling of the tissues of the nasopharyngeal cavity.

Typical indications for the use of nasal drops:

• acute sinusitis - inflammation of the epithelial covering of the paranasal sinuses, resulting from the complicated course of influenza and other acute respiratory viral infections;
• allergic rhinitis - hay fever, characterized by episodic disturbances in nasal breathing and accompanied by abundant production of mucus;
• nasopharyngitis - catarrhal damage to the mucous membrane of the tissues of the nasopharyngeal cavity, predominantly of infectious etiology, associated with the development of the inflammatory process, hyperemia and swelling of the walls of the organ;
• otitis media of the middle segment of the auricles - acute inflammation of the space between the tympanic membrane and the inner part of the auditory cavity, where the Eustachian tubes begin;
• laryngitis - infectious infection of the mucous membrane of the larynx, a typical complication of measles, whooping cough, scarlet fever, and other diseases of bacterial and viral genesis;
• eustachitis - inflammatory lesion of the auditory tubes.

Sanorin is used for physiotherapeutic procedures, surgical procedures, instrumental diagnostics of the nasal cavity. The drug can be used to quickly stop bleeding from the cavity of the respiratory organ.

Contraindications

Otolaryngological medication should not be used with increased sensitivity (hypersensitivity) to naphazoline nitrate and other components of the chemical formula of the drug.

Sanorin belongs to the category of potent drugs. Nasal drops have a number of absolute clinical contraindications and situational restrictions on their use. Affordable price and the presence of a large number of analogues compensate for the impressive list of medical bans.

Sanorin is not prescribed for:

• atrophic and chronic rhinitis - a decrease in the functions of the epithelial coating, receptors and nerve endings located in it;
• severe atherosclerosis;
• high blood pressure;
• cardiovascular dysfunctions - arrhythmias, tachycardia, others;
• angle-closure glaucoma and other severe pathologies of the optic organ;
• endocrine disorders;
• thyrotoxicosis - a significant increase in the production of thyroid hormones;
• chronic liver and kidney diseases.

The relative prohibitions on taking Sanorin include cardiac ischemia. The drug should be used with caution in case of pheochromocytoma and other hormone-dependent neoplastic neoplasms.

Nasal drops for men with severe prostatic hyperplasia are prescribed after consulting a urologist and under constant medical supervision. It is undesirable for women during pregnancy and lactation to use Sanorin. In urgent need, you should consult a gynecologist or neonatologist.

At what age can the drug be used?

Sanorin in the form of nasal drops with an active ingredient content of 0.05% is prescribed for children from 2 years of age.

Instructions for use, dosage

The medicinal solution is intended exclusively for intranasal administration. For colds and inflammations of the upper respiratory tract, patients over 15 years of age are prescribed no more than 3 drops in each nostril 3-4 times a day.

This dosage is relevant for sinusitis, exacerbated rhinitis, lesions of the Eustachian tubes. Adults and adolescents from 15 years old are prescribed Sanorin with an active ingredient concentration of 0.1%. For children, use drops of 0.05% in a similar dosage.

The frequency of application is selected depending on the severity of the pathological process. The recommended time interval between treatments is at least 4 hours. The drug is used for a short time or as a course method as prescribed by an otolaryngologist for a week for adults and 3 days for children.

With the rapid achievement of the desired therapeutic effect, the instillation is canceled earlier. After a few days, in case of the appearance of inflammatory symptoms and difficulty in breathing, the course can be repeated. To stop bleeding, a cotton swab moistened with a medicinal solution is placed in the nasal cavity.

When carrying out rhinoscopic diagnostics, to prolong surface anesthesia, 3 drops of Sanorin are introduced intranasally into each nostril together with 1 ml of anesthetic medicine. The drug is used in the complex therapy of infectious conjunctivitis.

Side effects

When taken intranasally, negative consequences are rare. Possibly upset stomach if drops are swallowed. The drug can cause migraine and increase nervous excitability in people with hypersensitivity to the components of the drug.

Sanorin - nasal drops (the price of the medicine depends on the concentration of the active substance), which can cause other side effects. Patients with cardiovascular dysfunction may experience hypertension or tachycardia.

In rare cases, allergic reactions are observed in the form of a rash on the face and hands, profuse sweating, itching. From local anaphylactic manifestations, dryness of the mucous membrane of the nasal cavity, a slight burning sensation are noted.

Swelling of organ tissues and reactive hyperemia of the epithelial covering of the sinuses were recorded. With prolonged use of Sanorin, skin irritation, atrophic state of the mucous membrane, narrowing of the nasal passages are noted.

When used in the recommended dosage, the drops are well tolerated by the vast majority of patients. Local allergic reactions develop due to the stimulation of naphazoline nitrate of adrenergic receptors of mast cells, which leads to an increase in their release of histamine.

Overdose

With intranasal administration of the drug, signs of drug intoxication are not recorded.

When the medicinal solution enters the gastrointestinal tract structure, it is theoretically possible:

• dyspepsia;
• heart palpitations;
• increased blood pressure;
• tremor;
• cyanosis - an increase in the content of carbhemoglobin in the blood;
• depression of the central nervous system, accompanied by a decrease in body temperature, general weakness, drowsiness.

To eliminate such conditions, the course of treatment with Sanorin is canceled and the means of symptomatic therapy are used.

special instructions

Long-term systematic intake of otolaryngological medication is addictive, which leads to a decrease in the anti-congestive (decongestant) action and vasoconstrictor effect.

Sanorin should be used only in the recommended dosage and the period of time calculated by the doctor. The drug can cause resorptive reactions associated with the absorption of the active substance into the systemic circulation.

Sanorin does not affect the ability to drive vehicles and work with dangerous machinery. When taken in the recommended dosage, it does not reduce concentration, does not inhibit mental activity, and does not alter natural psychomotor reactions.

There is no information on the ability of pharmacologically active components to overcome the placental barrier and penetrate into breast milk. During pregnancy and lactation, it is advisable to refrain from taking Sanorin.

When prescribing a drug for general anesthesia, when carrying out rhinoplastic manipulation, patients with hypersensitivity of the myocardium to sympathomimetics should be extremely careful.

Drug interactions

Sanorin - nasal drops (the price of the medication is lower than the cost of many analogues), which are forbidden to be combined with systemic monoamine oxidase inhibitors. This increases the risk of developing hypertension.

Such a negative effect is caused by the parallel administration of an otolaryngological drug solution and tricyclic antidepressants. Their combination accelerates the release of deposited catecholamines.

You can start taking Sanorin 2 weeks after stopping tricyclic antidepressants or monoamine oxidase inhibitors. Nasal drops affect the rate of absorption of local anesthetics by speeding up or slowing down their action, depending on the type of drug.

Analogs

In the presence of contraindications or increased sensitivity to the components of the medicinal solution Sanorin can be replaced with another vasoconstrictor drug with the same pharmacological principle. actions.

Top 5 most popular and affordable nasal drops:

• Nazol. Inexpensive drug based on oxymetazoline hydrochloride. Has a pronounced vasoconstrictor effect. The active component of the drops is characterized by adrenomimetic activity. It is prescribed for viral and bacterial infections and colds of the upper respiratory canals. Shown for children from 6 years old. Estimated price - 110 rubles.
• Lazorin. Improves nasal breathing, reduces exudation, narrows the capillaries of the mucous membrane. Used in the treatment of chronic sinusitis, hay fever, aggravated rhinitis. It is contraindicated in angle-closure glaucoma. The price of a 10 ml bottle is 450 rubles.
• Sinuforte. Nasal drops designed to suppress the inflammatory process in the paranasal sinuses. Fully plant based. The pharmacologically active substance is cyclamen extract, which causes reflex secretion in the mucous membranes of the paranasal sinuses. Price - 230 rubles.
• Galazolin. Vasoconstrictor drops, actively used in ENT practice. They have a good therapeutic effect, an affordable price and a high safety profile. The active ingredient is an imidazoline derivative. The drug reduces pathological exudation in colds and facilitates nasal breathing. Used for rhinitis of allergic, viral and bacterial genesis. It is effective in preparation for diagnostic procedures and rhinoplasty. Galazolin in pharmacies costs about 40 rubles. for a bottle of 10 ml.
• Xylometazoline. A popular vasoconstrictor medication in the form of nasal drops. Used for acute respiratory diseases, hay fever, sinusitis. Shown for children from 4 years old. They are used in case of a situational need or in a course manner as part of complex therapy. The cost of the drug is 110 rubles.

In ENT practice, Naphazin, Xilen and other nasal drops with a principle of action similar to Sanorin are actively used.

Terms, conditions of sale and storage

The drug can be purchased freely at any pharmacy. No recipe required. Sanorin is suitable for use for 4 years from the date of issue. Store the medication in a cool, dark place out of the reach of children.

Price

The otolaryngological drug Sanorin costs about 150 rubles in pharmacies. The price depends on the concentration of the active substance and the region. Nasal drops are an inexpensive, but effective tool for quickly eliminating congestion in organ cavities and relieving tissue swelling.

Video about drops Sanorin

Indications for taking Sanorin drops: