Creatinine in the blood. The norm for women, men over the age of, the table. Which means an increased, reduced, in patients with renal insufficiency. Analysis of the cause and treatment of folk remedies, Drug

Creatinine - the product of a chemical reaction in the body. Formed in muscles and released into the bloodstream. Normal levels of nonprotein compound - good indicator of the kidneys and of the whole organism.

What is creatinine and for which it is responsible

Creatinine (blood rate nonprotein compound depends on many factors) - is one of the substances in the final exchange of simple and complex proteins. When proper working body is excreted with urine. Compound creatinine is formed from creatine protein which is a basis for the activity of skeletal muscle in the body.

This complex process of chemical transformations protein creatine is stored in a new form - phosphocreatine, which is the energy for the contraction of muscle fibers in the body.

At the same time it gives its energy to the body, and itself divided on the final products of metabolism - creatinine, water and phosphates. Thus, non-proteinaceous compound is the final product, which is involved in the energy metabolism of the organism.

The norm in blood creatinine

Creatinine - participant of the energy metabolism in the body's muscles and other organs. Therefore, blood nonprotein compound content depends on the volume of muscle. Hence men in serum creatinine is in greater numbers than women - because of the amount of muscle mass.

Normally, a substance in the blood is almost always a certain amount, which is determined by the relative stability of muscle volume.

The dangerous deviation from the norm

Creatinine (blood rate - teamwork indicator organism) must have a stable value in biochemical analysis of blood and any deviations - up or down to be regarded as the pathological process in the body.

Increase in serum creatinine:

• acute renal pathologic state, in which the body is not able to fully or partially urine output;
• long progressive decline in renal function in a insufficient blood filtration, removal of metabolic products and withdrawal from the body of excess fluid;
• In chronic pathologies occurring in the myocardium and blood vessels;
• impressive size burns on the body;
• after major surgery on the muscles of the body;
• neoplasms, both benign and malignant;
• pathological process in the thyroid or pituitary gland;
• great loss of body fluids;
• nephrectomy;
• creatinine increase, as a result of medication;
• a large amount of protein in the diet food.

Reduced serum creatinine:

• long vegetable diet;
• weight loss with reduced muscle volume;
• the first 30 weeks of pregnancy;
• systemic glucocorticoid therapy;
• Stage 4 cancer;
• generating a violation vasopressin;
• swelling;
• lupus nephritis;
• psycho-emotional overload;
• ischemic stroke;
• the heat of passion;
• stress;
• chronic inflammatory processes in the liver;
• poor circulation in the hepatobiliary system;
• nephropathy;
• pyelonephritis;
• kidney stone formation.

As the effect of age on serum creatinine

Creatinine levels in the blood depends not only on gender, but also age. The older the person, the lower the level of the final non-protein compounds in the body. Associated with age-related decrease in the process of muscle volume - as body fat, because of slow metabolic processes, increases and decreases muscle.

Therefore, lower rates of creatinine in the normal state of health, are the norm.

But people in the later years of the final product the level of muscle work can be upgraded (To the normal middle-aged people) - if an elderly person leads an active life, is engaged physical exercise. In this case, the normal amount of muscle will keep the level of non-protein compound at the required level.

Table of norms for adults

Kreatinan blood (norm is defined in mmol / l) in men and women - a different value due to musculoskeletal structures.

creatinine in men over the age of:

Age men	creatinine in mmol / l	mg%
18 years to 55 years	from 0.085 mmol / l to 0.15 mmol / L	from 0.9615% up to 1.6968%
55 years to 75 years	from 0.07 mmol / L to 0.11 mmol / L	0,7918% up to 1.2443%
by 75+	from 0.06 mmol / L to 0.11 mmol / L	0,6787% up to 1.2443%

creatinine for women by age:

women age	creatinine in mmol / l	mg%
18 years to 20 years	0.05 mmol / L to 0.10 mmol /	from 0.5655% to 1,13,11%
21 years to 50 years	0.05 mmol / L to 0.11 mmol / L	from 0.5655% up to 1.2443%
51 years to 60 years	0.05 mmol / L to 1.06 mmol / L	from 0.5655% up to 0.6787%
61 years to 70 years	0.05 mmol / L to 0.98 mmol / L	from 0.5655% up to 1.1085%
by 71+	0.05 mmol / L to 0.80 mmol / L	from 0.5655% up to 0.9049%

Table of standards for children

creatinine index in children does not depend on gender. Please be aware that an increased rate of non-protein compound in the blood may be an absolute health of the child - physiological indicators that provoked exercise, overweight, increased consumption of meat products, taking medicines drugs.

Childhood	creatinine in mmol / l	mg%
to 12 months	from 0.017 mmol / l to 0.36 mmol / L	from 0.1531% up to 0.3243%
1 year 12 years	from 0.026 mmol / l up to 0.063 mmol / l	from 0.2342% up to 0.5675%
13 years to 18 years	0.045 mmol / l up to 0.089 mmol / l	from 0.4054% up to 0.8017%

Reasons creatinine abnormalities

At elevated, as well as at low creatinine levels have their own reasons. They may have pathological and physiological principle.

Pathologically elevated creatinine - the reasons:

• glomerular nephritis or glomerular nephritis;
• bacterial damage of the renal pelvis;
• malignant and benign urinary system;
• total body edema caused by renal disease;
• generalized ischemia kidney tissue;
• mochesolevoy diathesis;
• nephrolithiasis or formation of crystals in the renal tissue of various natures;
• kidney disease where, for unknown reasons, multiple cystic lesion formed bodies;
• renal dystrophy protein to form a protein-polysaccharide pathological compliment;
• lingering long flowing process of renal tissue destruction, which leads to an imbalance in the work of all internal organs and systems;
• acute pathology in the kidney associated with absorption disorder and sucking the liquid, which leads to disruption of metabolic processes in the body;
• restriction renal vascular system, owing to high blood sugar, which leads to glomerulosclerosis;
• inflammatory liver injury leading to disruption of methylation - important biochemical processes in the body;
• violation of myocardial perfusion, as a consequence of the defeat of the vascular system;
• pathological process in the organism, manifesting itself dying off of body tissues for various reasons;
• deep penetration of heat in the skin layers;
• germination malignancies in deep muscle layers of the body;
• long flowing in the thyroid pathology with reduced generation pituitary thyroid stimulating hormone;
• fluid loss of various etiology;
• the effects of radiation therapy;
• long flowing pathological increase in blood pressure;
• inflammation of skeletal muscles;
• muscular system autoimmune disease;
• deficiency of circulating blood of various etiology;
• violation pituitary work in the form of increased growth hormone and increase of body parts;
• serious infectious disease of the body;
• leptospirosis.

The reasons for non-pathological nature of the increase in serum creatinine should include such processes:

• strong physical fatigue;
• class heavy sports - powerlifting, bodybuilding, tennis, triathlon;
• unbalanced low-calorie protein diet;
• preparations of NSAIDs;
• excessive weight;
• period of organism growth.

Causes of low serum creatinine:

• extreme depletion of the body;
• myotonic muscle wasting;
• the first 30 weeks of pregnancy;
• the rejection of meat eating and the predominance of plant foods in the diet;
• systemic glucocorticosteroid therapy in autoimmune pathologies;
• hypoxia all body tissues of various etiology;
• disease, due to malfunction of the internal organs and systems;
• infectious diseases with severe leakage.

Symptoms of abnormal

Norm parameters in blood creatinine may vary and are always accompanied by certain symptoms.

Manifestations of elevated creatinine:

• palpitations and shortness of breath;
• fatigue;
• raising or lowering the blood pressure;
• incoherent thinking;
• inability to think, and to think clearly;
• great desire to drink;
• abnormal accumulation of fluid in tissues and organs;
• vomiting reflex;
• heaviness in the stomach;
• violation of water and lipid metabolism in the form of dry skin;
• pain and muscle weakness;
• conversely increased or reduced separation of urine during the day;
• Pathological changes in the total urine - the appearance of a protein and leykotsitopeniya erythropenia;
• painful, and painful sensations in the area of ​​the lumbar spine;
• hypertension.

Symptoms of low levels of creatinine in the blood serum:

• malabsorption of nutrients;
• dyspepsia;
• disorders of the digestive system of unknown etiology;
• failure of the hepatobiliary system;
• a feeling of weakness in the whole body;
• anorexia;
• motor and reduction of physical activity;
• pain in the cardiac muscle;
• asthenic condition;
• psycho-emotional instability.

Indications for use of analysis

The main indication for the purpose of analysis on the amount of creatinine in the blood - is the definition of how the urinary system works correctly.

You should know that there is pathology, the development of which can be determined by the level of non-protein compounds in the blood:

• edema syndrome;
• violation of the separation of urine - reduction or termination;
• pain and heaviness in the lumbar spine is not degenerative;
• heaviness in breathing;
• severe fatigue;
• pathological changes in the myocardium;
• autoimmune pathological processes in the body associated with visceral lesions;
• diabetes type 1 and 2;
• clinical and biochemical tests before surgery;
• gestation period of gestation;
• systemic glucocorticoid therapy;
• receiving antibacterial agents;
• in athletes, to control the correct operation of the kidneys during reception kreatinsoderzhaschih protein- and additives;
• inconstant pressure increase;
• hypertensive crises with pathological atherosclerotic vascular disease;
• painful spasm of the muscles of the body;
• postoperative period on large body surfaces.

Preparation for analysis

Prior to the analysis of creatinine in the blood should surrender to perform certain rules in order to avoid distortions in the analysis:

• necessary to exclude any kind of alcohol one day before delivery of the analysis;
• should abandon the large consumption of protein foods (if you have the habit of eating meat one), to analysis showed no artificial increase of creatinine in the blood;
• excluded from the diet per day spicy seasonings and salt-pickled foods;
• not to engage in heavy physical activities and sports for 2 days (before the blood donation);
• to delivery of the analysis should not take food for 12 hours;
• eliminate the psycho-emotional stress;
• before blood donation, except for a glass of water - you can not drink anything;
• Be sure to warn the healthcare professional about taking systemic medications - anti-bacterial anti-tuberculosis therapy, glucocorticoid medications (if any);
• if there is an opportunity (to resolve the attending physician) - terminate the use of all drugs;
• before entering into the manipulation room should relax.

Analysis

The order of delivery of the biochemical analysis of creatinine - a normal sampling of venous blood from the ulnar fold (in the absence of the opportunity to take blood in this place, it is necessary to take blood from the wrist, shoulder or legs).

But sometimes the doctor may prescribe specific tests for certain methods:

• The clearance of endogenous creatinine or Reberga sample. The method consists in the fact that the patient needs to turn venous assay creatinine, drink 0.5 L of pure water. Then you should go to the toilet and empty your bladder of accumulated urine and deliver as planned, the blood from a vein.
• Analysis using medical strips. Determination of creatinine in the blood with the help of strips is a rapid method. On special medical strip should apply a drop of blood (in this case, the blood taken from the finger). Method questionable and should be used only in emergency - intensive care cases.
• Creatinine Clearance by the method of Cockcroft and Gault. Venipuncture should take blood. But the calculation of the analysis must take into account the patient's age and body weight. Method evaluated the quality of renal excretory system.
• Jaffe reaction. When using the Jaffe reaction, in determining the amount of creatinine in the blood in the venous blood doctor - assistant adds pinkrinovuyu acid, which changes the color of the compound. In terms of the resulting color is determined by the amount of creatinine.

Methods for normalization of creatinine

In determining the level of creatinine, a doctor therapist primarily aims to see the result of the analysis. As a rule, he is interested in, whether in serum non-protein substance is enhanced.

usually followed for the normalization of low serum creatinine to adjust the physical and emotional load, give up bad habits as alcohol, tobacco, inactivity - the enemy low creatinine. To reduce the level of creatinine in the blood should be aware of the cause.

Based on the survey of physician, urologist, infectious diseases (all depends on the pathological process) will offer therapy:

• drug therapy (in the case of having the disease);
• Alternative treatment (traditional medicine);
• diet food.

How to increase the level of creatinine with medication

In order to increase the blood creatinine level should know the reason. The lack of non-protein compounds, as a rule, doctors do not bother, and this problem should be treated in the first all dietary compliance - with a high content of animal protein, the active image life.

But there are pathological states in which the drugs should be taken to help the general metabolism in the body.

Methionine drug in tablets:

• means included in the alipoficheskaya sulfur containing amino acid;
• formulation stimulates the liver normalizes lipid metabolism, stimulates the production of vitamin B4, epinephrine and nonprotein hormone substance creatinine;
• It is taken in liver lesions of different etiology, diabetes type 1 and 2;
• to increase the level of creatinine in the blood should take 2 tablets 4 times a day. The duration of therapy from 15 to 30 days with an interval of 2 weeks should be given a second course.

Tablets Ketosteril:

• combined amino acid-polypeptide preparation which contains - a hydroxyamino acid, L-tryptophan, heterocyclic amino acid, alpha-amino acid;
• the drug helps the body in replenishing for the life of the missing amino acids contributes to the development of creatinine, improves metabolic processes;
• the drug must be used when there is insufficient protein metabolism;
• means you need to drink 4 tablets 3 times a day. The duration of therapy is determined by a therapist.

Nutrizone dry preparation for oral administration:

• in a preparation containing proteins - 6 g, fat - 5.8 g, carbohydrates - 18.3 g;
• is a state of high drug mixture with a large amount of protein, vitamins, fats, and carbohydrates;
• drug should be taken during exhaustion, lack of blood creatinine;
• fine powder to be added to food or to be diluted with water and drink. Dose determined by the physician or therapist nutritionist according to the patient's needs.

Drug Modulen IBD:

• of a preparation for oral administration includes a large amount of protein, a polyunsaturated fatty acid omega-3 and omega-6, mealy corn syrup carbohydrate, sugar cane;
• a highly combined protein powder to eliminate protein deficiency, decreased creatinine levels in the blood serum, anorexia;
• drug should be added to food or drink do. Take should be strictly prescribed by a doctor and under prescribed dosages.

The preparation for intravenous administration Nutriflex lipid:

• medicament comprises a liquid solution of grape sugar, restoring emulsion of lipids, amino acid composition, the ionic salt solution;
• preparation provides energy to all cells and tissues;
• the drug to be administered intravenously, continuously, in dosages and amounts prescribed by a physician or other resuscitator and only a specialist in the hospital.

Lowering creatinine drugs

Blood creatinine (normal nonprotein compound increased in certain diseases) can have no only a reduced level (a rare event), but also increased, to which should be taken very Really.

The first step is to change your lifestyle:

• be sure to adjust the use of clean water - no tea and coffee;
• reduce and sometimes eliminate (for a while) exercise;
• eliminate Psychoemotional instigators;
• should give up bad habits - alcohol, in all kinds of tobacco.

drug therapy

Drug Therapy elevated creatinine comprises subjecting to provoking factors increasing non-protein compound.

Trinefron capsules for oral use:

• of the plant combined preparation include grass centaury, rosemary leaves medicinal root Lyubchik;
• formulation applied in urology practice for disorders of the urinary system and elevated levels of creatinine;
• the drug should be applied to 2 capsules 3 times a day with a large volume of liquid. Duration of therapy urologist determines based on the general condition of the patient and biochemical analyzes.

Pills cystitis Aurina:

• of the drug includes an extract from golden rod bush, stearic acid, magnesium, silica, natural polymer polisorb;
• extract of the shrub golden rod affects the urinary system, stimulates the removal of urine, reduces inflammation, thereby reduces the level of creatinine in the blood plasma;
• the drug must be taken for a long time, at least 2-3 months in a dose - 1 tablet 4 times a day.

Liquid detergent Lispefril:

• of the liquid agent includes a plant extract from the two-color lespedeza, ethyl alcohol, anise essential oil;
• complex of the drug improves renal filtration, discharge of urine promotes sodium selection. Thus, it contributes to lowering the level of creatinine;
• the drug should be used for at least 1 month to 1 h. l. - 1 tbsp. l. preparation (can be diluted in water) 3 times a day.

Normalization of creatinine folk remedies

Alternative Medicine widely used to normalize the levels of non-protein compounds in the blood. To do this, use herbal teas and infusions of plants, prepared at home.

1. Cinnamomum Ceylon tea. The dried bark of the tree should be brewed as a tea and drink 3 times a day before meals. It helps to improve urine output.
2. Taraxacum officinale. The plant is to be used for brewing tea, as well as add to the dishes in cheese and dried. Helps the urinary system, contributing to the overall strengthening of the body, it is a tonic.
3. Drink from the berries of wild rose. Berries should be steamed in a thermos. Infusion take the form of loosely as a beverage, can, instead of water. Enhances diuresis, it stimulates the removal of small crystals from the kidneys, thus improves circulation in the urinary system, and decreases the level of creatinine;
4. Tea made from berries and leaves of bilberry garden. A small amount of funds necessary to pour into a glass, pour boiling water. Insist. Used instead of tea 3 times a day. It helps the separation of urine.
5. A decoction of sage. It helps to improve kidney function, as well as the output of creatinine surplus. It brew 1 h. l. herb with boiling water, wait until the infusion (15-20 minutes) and have a drink before eating.

Dieting at elevated creatinine

At elevated creatinine necessarily comes to the forefront respect for the right diet, which will help lower the level of the non-protein substance in the blood. Just food diet in the treatment with drugs will quickly result in high rates of normal biochemical analyzes and help the general state of the organism.

You should know the principles of diet with high or elevated levels of non-protein substances:

• proper drinking regime. If there are no restrictions on the part of the physician, the use should be up to 2 liters of clean liquid or herbal teas a day. This is a prerequisite, which stimulates the removal of toxins from the body;
• to normalize the level of creatinine in the blood should be avoided or minimized the use of animal protein;
• diet should be enriched with vegetables, cereals, fruit, unrefined oil, milk products, bread from whole wheat;
• food must be fractional - 3 main meals and two snacks.

creatinine level - is a constant. In order to be the amount of non-protein compounds in the blood was within the normal range should lead a healthy a lifestyle that includes a balanced diet and exercise, as well as avoiding harmful habits.

Useful video of creatinine, its norm and deviation

For more information about the reasons for his creatinine and increase or decrease:

Diet to lower creatinine: