Instructions for use indicates that the cream "Komfoderm" helps to cope with many dermatological problems, has many properties. Doctors recommend to patients since it differs low cost and high efficiency.
Self medication is helping eliminate the negative symptoms of various diseases of the epidermis, so often used in dermatology. Buy medication can be in almost any pharmacy network. It is necessary to purchase a prescription. The cost of drugs varies from 250 to 500 rubles.
The content of the article:
- 1 Indications
- 2 Chemical composition
- 3 In what form is available
- 4 pharmacodynamics
- 5 Pharmacokinetics
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6 application
- 6.1 For children up to 18 years
- 6.2 adult
- 6.3 For pregnant
- 6.4 for elderly
- 7 Contraindications
- 8 Overdose
- 9 Side effects
- 10 drug interactions
- 11 Conditions and terms
- 12 analogs
- 13 Video of hormonal ointments
Indications
Cream Komfoderm, instructions for use which indicates that use it only externally, appointed by dermatologists in diseases of the epidermal inflammatory or allergic nature, with eczema development.
Doctors prescribe medication in the following cases:
- infectious diseases of the epidermis;
- dermal inflammatory disease;
- dermatitis of various etiology;
- eczema.
Komfoderm also assigned in the presence of high susceptibility to other glucocorticosteroids. The drug itself acts as a synthetic glucocorticosteroid and keratolytic agents.
Chemical composition
The cream includes a main active component - methylprednisolone atsepona in an amount of 0.1 g. Also as part of the drug is present in an amount of urea, 2 g. As auxiliary components are: demitekon, ceramides, propilengltkol, potassium dihydrogen phosphate, cetyl alcohol and others.
Young parents on the advice of doctors used medication for the treatment of diaper dermatitis in infants. According to reviews, the drug helped to cope with the problem in a short period of time.
Other consumers used drug for the therapy of allergic dermatitis in conjunction with the reception of antihistamines. The effect was observed already on the third day of treatment.
Almost all consumers say low cost drugs, its high efficiency, and the inconvenience of using the cream because the small size of the tube. When applying the cream appears peculiar smell, which eventually passes. The drug is rapidly absorbed, leaving no greasy residue. In addition, it promotes hydration of the skin.
This medication does not cure the cause of the abnormalities, but only eliminates the symptoms. For example, in the treatment of atopic dermatitis, many recommend the co-administration of antihistamines. Without their use of treatment of diseases will be incomplete.
In what form is available
Komfoderm comes to pharmaceutical market in two forms - creams and ointments. The drug has a slight aroma, its color - white. Cream in an amount of 30 grams. placed in an aluminum tube, which, together with the summary on the use placed in a cardboard box.
Available medication Russian pharmaceutical company. The cost of medications may vary slightly depending on the pharmacy network. Drug is released only by prescription of the doctor. Engage in self unacceptable.
pharmacodynamics
Methylprednisolone aceponate is the main active component of the drug. This substance - synthetic steroid. It ensures stopping of inflammation and allergic reactions in the epidermis, resulting in reduced symptoms and discomfort.
Methylprednisolone aceponate okazvaetsya effect on the pathological processes that occur in the skin, complex. He reduces the susceptibility of mucosal epithelium of the influence of the drug, it stops the development of shock. Also active substance fluid improves release from damaged tissues, and normalizes blood circulation.
Cream Komfoderm, application instruction is confirmed after application improves the activity of hormones, slows the activity of white blood cells, activates the synthesis of cells that absorb pathogenic germs.
Methylprednisolone aceponate stops delivery of leukocytes in inflammatory center, it also increases the strength of the capillaries, promotes activation of collagen synthesis. When using the drug slows the production of thyroid hormones and follicle stimulating hormone.
When using the cream at a dosage that is indicated in the summary, its local effect will manifest itself is minimal. But even with its repeated application over large areas of the epidermis, or the application of cream under the bandage will not impair the operation of the adrenal glands, as well as to change the level of cortisol.
Active substance "Komfoderm" gets into the cells and is associated there with the glucocorticoid receptors, forming a complex of steroid receptors.
He, in turn, binds to the DNA of T-lymphocytes, leading to a variety of functional and morphological changes in including an increase in the rate of synthesis macrocortin, which slows or stops the formation of mediators inflammation. All this leads to a narrowing of blood vessels and reduce blood flow in them.
Urea, which is also present in the composition of medical tools, has moisturizing effect, contributes to the destruction of excess horny layer of the epidermis. It binds water, thereby softening the horny layer of the epidermis. Thus, the skin becomes soft, moist and flexible. Urea also can change the properties of the protein.
This material serves as a conduit of drugs into the deeper layers of skin. It has antifungal and antimicrobial effect and accelerate the wound healing process.
Urea acts as a good exfoliant, it helps to exfoliate dead skin cells. This substance on the skin creates a protective film, preventing the ingress of pathogenic microbes on its surface.
Pharmacokinetics
Active substance penetrates into the deeper layers and it begins to interact with water after application of the cream for the epidermis. The therapeutic effect begins to appear for one hour. A small portion of the drug into the bloodstream.
There it reacts with the hyaluronic acid. Over 16 hours of metabolites excreted by the kidneys begin in the body, they do not accumulate. The drug is not addictive. Urea does not enter the bloodstream, so the risk of allergic reactions is minimal.
How quickly the cream will get into deeper layers of the epidermis, it depends on the condition of the skin, blood vessels, and also on the method of use of the drug (with or without a bandage it).
application
Cream Komfoderm, instructions for use which should be examined prior to starting therapy, should only be used externally. Specific instructions on the use of the cream is not.
For children up to 18 years
This medication is allowed to be used for children with four months of age. In this case, used only 1 time per day. It in a small amount is applied to the affected area. therapy is not more than four weeks. Doctor develop a treatment regimen in a particular case.
adult
Adults also need to apply the medicine once a day. Therapy may continue for up to three months. Doctor assigns the duration of treatment in each case.
In the presence of pathological skin therapy should be held no more than five days. Throughout the year can be several times to carry out the treatment.
For pregnant
The medicament may be for use during pregnancy and breast-feeding a baby, but strictly on the testimony of the doctor. Only it should in such cases, administer, and to paint a particular treatment regimen.
When using the "Komfoderma" while carrying a child must be in small quantities to put it, the course of therapy should also be short. It is not recommended to apply the cream on the mammary glands during lactation.
for elderly
In old age, the drug is also used. Special restrictions in its application no. The drug should not be used only for the treatment of acute inflammatory diseases.
Contraindications
The medication has some limitations in the use of:
- Hypersensitivity to the components of the drug.
- The manifestation of symptoms of tuberculosis or syphilis in the ground application of the cream.
- Disease viral nature, eg, papillomavirus, herpes zoster.
- The presence of ulcers and warts on the skin.
- Local reactions to vaccination.
- Children up to four months.
With care prescribe medication to those who have eye disease, as the product is not used in ophthalmology. You can not allow the drug to the organs of sight and in the mucosal epithelium.
For external use of the drug for a long time and in large quantities the risk of developing glaucoma occurs near the eye.
Overdose
In medical practice there were no cases of drug poisoning. When testing medical poisoning risk has not been identified medication for at it ingested or when used in large quantities over large areas epidermis.
If the drug is used long enough, you may receive the atrophy of the epidermis.
Among its symptoms include:
- change the color of the dermis;
- thinning of the fat;
- dry skin;
- the formation of vascular network;
- flaccidity and wrinkles;
- decreased skin elasticity.
With the development of the first signs of atrophy is recommended to cancel the use of drugs. If negative symptoms does not pass, you need to go to the clinic.
Side effects
Typically the medication is well tolerated by all patients, regardless of age.
Sometimes the side reactions may occur:
Organs and tissues | Seldom | Rarely |
Skin and subcutaneous tissue | Dermatitis, pigmentation of the skin, allergic rashes. | skin atrophy, striae. |
local reactions | Folliculitis, hypertrichosis, active hair growth. | Burning, erythema, rash. |
In the formation of atrophy may appear streamers. Typically, this occurs if the agent is applied to the face of a long period of time. It recommended to discontinue its use and consult a family doctor if you have any adverse reactions. He will appoint an appropriate treatment and prescribe the drug analogue.
Medication has no effect on psychomotor reaction, so it can be used when driving or other complex mechanisms.
drug interactions
Cream Komfoderm, instructions for use is confirmed, it is often used in conjunction with antifungal drugs and antibiotics. However, any medication should be appointed strictly doctor.
Prohibited use of drugs together with other creams or ointments, as this may harm your health. Before applying the cream you need to consult with a specialist.
Conditions and terms
The preparation is stored in a dry, dark place where the temperature does not exceed 25 ° C. Children should not have access to medicines. the shelf life of the cream is 2 years from the date of issue. After the expiration of the drug shelf-life must be disposed of, absolutely can not use it.
analogs
Drug "Komfoderm" may be replaced by an analogue of the attending physician. The most suitable in this context are drugs that have similar composition and active ingredients. The most commonly prescribed drugs include "Advantan", "Sterokort", "Metizolon", "Methylprednisolone aceponate". All these drugs have similar therapeutic effects and composition.
Also, the doctor may prescribe and such medications as "Kutiveyt", "flutsinar", "Akriderm", "Mometasone." Similar therapeutic effect, but have different compositions such drugs as "Beloderm", "Betazon", "Celestoderm".
- "Advantan" It incorporates methylprednisolone 0.1% is discharged in the form of ointments, fatty ointments, emulsions and creams. Applied medicine for the treatment of dermatitis, dermatosis, eczema and burns. It eliminates the symptoms of skin allergies, good fights with the processes of inflammation.
- "Sterokort" - antimicrobial and antiseptic, synthetic glucocorticosteroid. Is used in dermatology for liquidation on the skin inflammation processes, stops the formation of scar tissue. The main active substance acts methylprednisolone aceponate 0.1%.
- "Methylprednisolone aceponate"- preparation that has anti-allergic effect in a short time eliminates inflammatory processes. It has a "Komfodermom" similar composition and therapeutic effect.
- "Kutiveyt" It incorporates the active ingredient fluticasone propionate in an amount of 50 g. The drug has anti-inflammatory effect and is often prescribed by dermatologists for treatment of skin pathologies. Available in the form of ointments and creams.
- "Flutsinar" It is a part of fluocinolone acetonide. Produced the drug in the form of ointments and gels. Used for the treatment of dermatitis, eczema, herpes, psoriasis severe.
- "Akriderm" submitted to pharmacological market in the form of lotions and ointments, the basic active substances act betamethasone dipropionate and gentamicin sulfate. The drug was well eliminates inflammatory processes, allergies, itching and swelling has antiexudativ effect.
- "Furoate" presented in the form of a spray to be applied only on the skin. The active substance - mometasone furoate - copes well with inflammation.
- "Beloderm" assigned to the therapy of dermatitis, eczema, itch, psoriasis, urticaria, herpes. Prperarat comes in one form - the ointment. It has as part of betamethasone dipropionate.
- "Betazon" - a corticosteroid used to treat diseases epidermisa.medikament marketed pharmacy only in the form of an ointment, is an analog of prednisolone. Often used in dermatology.
- "Celestoderm" It comes on the pharmacological market in dvuhformah - creams and ointments. Assigned vredstvo medicament for the treatment of neurodermatitis, eczema, psoriasis, dermatitis and other skin diseases. It has as part of betamethasone valerate.
Any analogue cream "Komfoderm" should be appointed doctor individually, self-development can cause serious consequences.
Cream "Komfoderm" - a combined drug. Instructions for use of the drug enclosed in each package, is an effective and inexpensive means, which helps for a short time to eliminate the negative symptoms of various skin disorders character.
Buy medicine only on doctor's orders, it costs relatively inexpensive and falls in almost every pharmacy network.
Komfoderm well tolerated by patients, does not cause allergic reactions, it has many useful properties. According to the instructions for use, it moisturizes, heals, eliminates the symptoms of skin disorders, anti-inflammatory, antibacterial and antiallergic effect.
Registration of the article: Vladimir the Great
Video of hormonal ointments
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