Dermoveyt ointment. Instructions for use, price, reviews, analogues

Dermoveyt ointment - a pharmaceutical agent used in the treatment of dermatological problems. Based on the information the official instructions, use extreme caution because of the content of the active glucocorticosteroid.

Shape and composition of the drug release

Hormonal agent is made in the form of ointments and creams for external use. Liniment is contained in aluminum tubes having a nominal volume of '25

The main component - clobetasol propionate.

Additional composition:

• White soft paraffin - 100 g;
• propylene glycol;
• sorbitan sesquioleate.

Means packaged on a cardboard package. Each package - 1 tube.

pharmacological properties

Ointment topical administration. Exhibits pronounced anti-inflammatory, antipruritic properties due to members of the steroid agent components.

Crack formation copes with exudative elements, removes signs of irritation, eliminates allergic reactions on the skin. Active components and prevent the accumulation of neutrophils formation elaboration of lymphokines. It is noted decrease in the migration macrophages, suppression and prevent further spread of infiltrative cells.

Pharmacodynamics and Pharmacokinetics

Deroveyt ointment, instructions for use which indicates the activity of the main component, exhibits some pharmacokinetic and pharmacodynamic properties.

The maximum concentration of active substance is 0.63 ng / ml. The level of concentration in blood plasma is thus observed after 13 after the application of liniment. Repeated use of the drug leads to maximum concentration of the active ingredient after 8 hours.

The average concentration of the ointment after repeated use is reduced to a small extent in comparison with the use of a cream.

After application in a volume of 0.25 g in lesions of eczema or psoriasis development of maximum values ​​of the active metabolite in the blood of 2.3 and 4.6 ng / ml, respectively.

Indications

The ointment used in the treatment of various forms of dermatitis, accompanied by inflammatory reactions, itching and other symptoms characteristic. Assigned in the absence of the effectiveness of other drugs belonging to NSAIDs.

Indications:

• Psoriasis, except patchy form of the disease;
• Various kinds and types of eczema;
• lupus erythematosus (discoid);
• intractable dermatoses treatment;
• lichen planus;
• other skin diseases, not amenable to treatment less active steroid topical administration preparations.

Ointment base is suitable in the presence of dry cells at the site of injury, accompanied by desquamation, hyperkeratosis development.

Contraindications

The drug has some limitations for use. Not used when signs of components of the high sensitivity to drugs.

Contraindications:

• the existence of infectious lesions on the skin;
• rosacea;
• acne rosacea;
• Acne lesion;
• perioral dermatitis form;
• pruritic moments in the absence of inflammatory processes of integuments;
• presence of itching of the anus and genitals;
• childhood;
• breastfeeding.

Extremely cautious medication indicated for allergic reactions to the steroid component, with the development of psoriasis, as well as in children and adolescents up to 18 years.

At what age can use the drug

Dermoveyt ointment, according to the official statement, authorized for use in children aged 1 year. In this case, treatment is carried out on the testimony of a specialist and only under his supervision.

Instructions for use, the dosage of the drug

Dosage means is calculated, based on the shape of the pathological process, patient's age and the individual characteristics of the organism responsive to corticosteroids. Adults are recommended to use the preparation two times a day. At high therapeutic efficacy and dosing frequency decreases.

In exacerbations or avoid the development of repeated defeats the means used in short courses and only a professional permit.

Elderly patients and children. The composition is applied 1-2 times a day within a short period of time. In the case of the high efficiency drug dose is reduced or replaced by other medical means, not belonging to the group of local corticosteroids.

In this therapy, in both cases should not be more than 1 month. Maximum weekly dose - less than '50 it is recommended to apply an occlusive dressing in severe cases, and if there are signs of hyperkeratosis. Use at night before going to bed.

Do not apply makeup to the face area because of the occurrence of side effects or withdrawal symptoms.

Side effects

In most cases, the drug was well tolerated by patients. However, occasionally develop adverse reactions caused by the excess of the daily dosage and the individual characteristics of the organism.

Side effects:

• The immune system: the formation of a generalized rash, increased sensitivity to the components.
• Endocrine system: rarely a decrease in function of the adrenal cortex, the hypothalamus-pituitary system, the development of Cushing's syndrome. Also notes a delay in development, increase in body weight in children. Often formed glaucoma, cataract, the first signs of hyperglycemia, increased blood pressure. In more rare cases, obesity occurs, there is brittle hair or alopecia, decreased cortisol levels.
• Skin and subcutaneous tissue: pruritic symptoms, rash, urticaria, pain at the site of application composition. Infrequently formed striae, atrophic changes occur skin - thinning, pigmentation. Prolonged use, particularly the use of occlusive dressings leads to the development of hypertrichosis, worsening of symptoms of disease. Also recorded allergic reactions, the occurrence of symptoms of contact dermatitis, pustular forms of psoriasis, erythema, acne.

When the negative effect of the development is necessary to cancel the use of the drug and consult your healthcare specialist for the appointment of symptomatic therapy.

Overdose

Dermoveyt ointment, instructions for use which requires careful use of tools, in violation of rules applying provokes various adverse reactions.

Excess dermatologist prescribed dose leads to systemic reactions. The main sign of overdose is hypercortisolism.

Require symptomatic treatment. Requires a gradual withdrawal of the drug. In this case, the medication necessary to replace other less potent steroid component. The process is carried out only under the supervision of a physician in order to prevent the development of adrenal insufficiency.

Further treatment is carried out according to the clinical picture and symptoms accompanying the disease process.

special instructions

If you experience symptoms of local allergic reactions has a similar clinical picture to the underlying disease.

In rare cases of adverse reactions observed glucocorticoid insufficiency. In such a case it is necessary to replace the medicament or other corticosteroids to reduce the daily dosage. Abrupt withdrawal drugs capable of provoking glucocorticoid withdrawal or failure.

Precipitating factor in the development of pathology and adverse reactions:

• exceeding the prescribed dose;
• the use of funds for large areas;
• prolonged use of assets belonging to local hormonal drugs;
• prolonged use of the drug under occlusive gauze or other enclosed areas;
• use on the face or other parts of the body with a thin skin;
• applying to the affected area.

The degree of absorption in children older than 1 year, much higher than the absorption of the active ingredients into adulthood, due to what the risks of side effects in children is several times higher than the occurrence of local adverse reactions in adults. The process is due to immaturity of the skin barrier.

Very carefully appointed ointment in children younger than 12 years because of the high risk of systemic effects, including suppression of the functional abilities of the adrenal cortex. Treatment in these patients is conducted under the supervision of a dermatologist. Duration of therapy in this case must be no more than 5 days.

The incidence of atrophic disorders in childhood more than in more than 2 times as compared with adult patients.

Dermoveyt ointment, instructions for use which permits the use of a means of skin with lesions of psoriasis used with extreme caution because of the high risk of recurrence of the disease, develop resistance to the components facilities. When this happens destruction of the skin barrier, thereby developing both systemic and local adverse reactions.

In outbreaks secondary forms of infection must hold an appropriate antibiotic treatment means. In the propagation of an infectious lesion is necessary to cancel the use of hormonal drugs and conduct anti-bacterial treatment.

The conditions created using occlusive dressings, or of the therapy of skin folds results in a form of bacterial infection. Before applying the gauze is recommended to clean the skin.

In some cases, liniment used for lesions in dermatitis shins location ulcerative elements. When applying the wrong means to develop local adverse reactions, as well as increases the risk of secondary infection.

In extreme cases, it may be applied as liniment on the face area. In this case, the affected area should be small. The duration of the treatment - no more than 5 days.

Allowed to use the medicament of the eyelids. However, when applying the composition of the need to exercise high caution to avoid falling off the drug in the eye. Accidental application liniment mucosal region promotes the development of cataracts and glaucoma. After contact with the drug in the eyes wash with normal warm water.

Studies on the effect of the drug on the ability to drive vehicles or to conduct work requiring increased psychomotor reactions were not carried out. According to these negative actions of the drug does not affect the implementation of such activities.

drug interactions

Concomitant use of drugs and steroid ointments, leading to inhibition of isozyme CYP3A4, causing in some cases, inhibition of metabolic processes glucocorticosteroid. The process is accompanied by the development of local side effects.

Indicators and manifestation degree of reaction depends on the dosage and method of use of the drug.

analogs

Dermoveyt ointment, instructions for use which expresses the possibility of side effects can sometimes be replaced by other steroids with moderate or low activity.

analogues:

• Delors. A pharmaceutical agent for external use. It is produced in the form of liniment - an ointment or cream. The active substance is clobetasol propionate. Glucocorticosteroid shows high efficacy in the treatment of inflammatory and infectious processes on the skin. Prescribed by the attending dermatologist at the development of various forms of dermatitis, a red shingles, contact dermatitis forms including urticaria. It has antipruritic and exudative action. Used in small areas under the supervision of a physician. Composition is applied 1-2 times a day. The duration of the therapeutic effects - no more than 1 month. When used on the face - no more than 5 days. Price - from 150 rubles.
• Karizon. Pharmacological agent based on active steroid - clobetasol propionate. In the sale received two dosage forms - ointment and cream. Action components aimed at eliminating allergic and inflammatory manifestations. It helps eliminate exudation signs, if itching, skin rash caused by dermatological diseases. Assigned for dermatitis of various etiologies, lichen planus, allergic reactions, caused by the interaction of skin with an allergen. It has multiple limitations. The composition is applied 1 time a day. Duration of treatment - no more than 4 weeks. Cost of equipment - from 135 rubles.
• Pauerkort. A steroidal agent for external use of the foreign producers (India). It has 2 main forms - ointment and cream. The composition includes active corticosteroid is clobetasol. It is used in dermatology for different kinds and types of dermatitis, including contact and allergic form. It exhibits a high degree of efficiency in the presence of exudate, inflammatory phenomena. Also used in the defeat of pink lichen. Liniment is applied 1-2 times per day, based on the severity of the symptoms and pathology. It requires constant monitoring specialist. Rate - no more than 1 month. Cost - from 50 to 592 rubles. per pack.
• Kloveyt. Means a local destination. The ointment base contains an active hormone component - clobetasol. The drug used in dermatology in the development of various skin diseases. Including dermatitis and some lichen. You can use tools as part of a treatment for eczema lesions. Active components contribute to the elimination of allergy symptoms, inflammatory reactions and eliminates elements exudative lesions in places. The composition is applied no more than 1-2 times a day. Duration of treatment - no more than 4 weeks. Before distribution of the composition is necessary to ensure there are no contraindications. The cost - 276-463 rubles.
• Klobeskin. Ointment bases for external use. Active agent consists of glucocorticosteroid hormone - clobetasol. Is assigned in case of psoriasis, eczema, various forms of dermatitis. Contraindication is the presence of inflammation and itching in the genital area, and also in the development of acne, including acne. Composition is applied 1-2 times a day. Duration of treatment hormone should not be more than 4 weeks. Very carefully administered to children under 12 years old. Requires constant monitoring specialist. Cost per package - from 140 rubles.

Independent selection and replacement of the drug can lead to negative manifestations. It is necessary to consult a dermatologist for the purpose analog. Selection is made based on individual characteristics of the organism.

Terms, conditions of sale and storage

• Store in a dark place where the temperature does not rise above 30 ° C.
• Shelf life - 2 years from date of manufacture.
• Do not use after the expiration date.

Prescription.

Price in drugstores of Moscow, St. Petersburg, regions

The cost of funds depends on the nominal amount of tubes and the sale, taking into account the trade network, by tempering pharmaceuticals.

Area / Region	Packing volume	cost of
Moscow, Moscow region	tube, 25 g of	334-1024 rubles.
St. Petersburg	tube, 25 g of	389-1075 rubles.
St. Petersburg (suburbs)	tube, 25 g of	375-1036 rubles.
Leningrad region	tube, 25 g of	345-1012 rubles.
Novgorod region	tube, 25 g of	376-650 rub.

Before using medications should consult a dermatologist or pharmacist and read carefully the formal instruction.

According to responses of patients who used Dermoveyt in the form of ointments, in most cases the therapeutic effect in the treatment of various skin lesions was achieved. 84% of all patients had higher efficacy against eczema, inflammatory processes. In rare cases, non-compliance with the instructions stated on the addiction to the components of the pharmaceutical agent.

Registration of the article: Vladimir the Great

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