Cere - complex nootropics, promote metabolism in the brain. Effect of the drug increases survival of neurons during oxygen deficiency or wrong of his assimilation.
Cere effectively cope with pathologies involving the violation of the most important functions of the brain in children, in which they recognize the world, analyze and store information. This is confirmed by reviews of neurosurgeons, neurologists and pediatricians.
The content of the article:
- 1 Release form and composition of the drug Cere
- 2 pharmacological properties
- 3 Pharmacodynamics and Pharmacokinetics
- 4 Indications
- 5 Contraindications
- 6 At what age can use the drug
- 7 Instructions for use, the dosage of the drug
- 8 The causes of inflammation after the injection
- 9 How to ease the pain after the injection Cere?
- 10 Side effects
- 11 Overdose
- 12 special instructions
- 13 drug interactions
- 14 analogs of Cere
- 15 Terms, conditions of sale and storage
- 16 Price in drugstores of Moscow, St. Petersburg, regions
- 17 Advantages and disadvantages of the drug
- 18 As Cerebrolysin affect sleep?
- 19 Videos about cerebrolysin
Release form and composition of the drug Cere
Means are prepared by solvolysis water matter of brain tissue.
The list of components of the drug include:
- complex peptides derived from porcine brain (15%);
- NaOH (sodium hydroxide);
- Special water for injection.
Cerebrolysin can purchase only as an injectable solution in a vial or ampoule brown.
Depending on the volume, the product package can be purchased at these variations:
- 10 vials, each of which is a volume of 1 ml or 2;
- 5 vials, each of which volume is 5, 10 or 20 ml;
- 1 vial of 30 ml.
pharmacological properties
Falling through the bloodstream to the brain neurons, the active peptides and amino acids catalyze metabolic pathways inherent in a particular organ. The medicament prevents neuronal damage when exposed to adverse factors and normalizes metabolism.
Cere and its analogs, as instructed, promote the passage of the cleavage reactions complex compounds in the brain tissue that result in production of large amounts of energy. Furthermore, the pharmacological properties of the drug is to improve the synthesis of proteins in aging brain cells.
Cerebrolysin reduces the harmful effects of breast coma in children. The mechanism of action of the drug, in the opinion of researchers is to improve stability of the brain cells to the damaging factors such as:
- low oxygen content;
- Reduced glucose concentration;
- toxins poisoning.
Cerebrolysin inhibits the oxidative processes in the body, thereby reducing the deleterious effects of free radicals in brain cells.
If you take regular medication, the mental activity to improve, it becomes easier to memorize and reproduce information, improve concentration, and normal mood. Also regresses changes electroencephalography characteristics.
Pharmacodynamics and Pharmacokinetics
Cere for children, real scientists which mostly positive, was the subject of multiple studies.
As a result, they found out that the use of this drug, you can:
- prevent myocardial infarction;
- remove puffiness;
- cause microcirculation to normal;
- to reduce the mortality rate.
Cere for children, about which research reviews also suggest that the drug agent has an effect on brain cells, it compensates the critical lack of energy in the body person. Moreover, it stimulates the increase in the number of molecules through the glucose transporter mechanism preventing ingress of harmful substances into the brain.
The preparation ensures that the synthesis and degradation metabolites physiological needs of the organism, and also removes chronic pain by acting on brain neurons.
In the analysis, being healthy people and patients with pathophysiological relationships presence of cerebrovascular diseases with impaired mental function, it turned out that when taking medications change the following parameters:
- It increases the activity of neurons;
- improve brain function;
- patients begin to perform daily tasks without assistance.
As a result of numerous experiments also it revealed that Cerebrolysin has no negative the impact on the human immune system does not encourage the formation of antibodies and does not affect the regulation of physiological processes.
Derived from porcine brain cells, the peptide fraction comprises identical to the human body biologically active peptides, so it is impossible to carry out pharmacokinetic studies.
Data obtained in pharmacodynamic assay shows that after being formed Injection drug stimulation and maintenance of neuronal development is determined for days in the plasma blood.
Indications
Cere is assigned if the patient is found degenerative dystrophic disorders in the brain in various pathologies of psychiatric and neurological.
The main indications for its reception are:
- Alzheimer's disease;
- concussion;
- ischemic stroke;
- violation of children's intellectual development;
- brain or spinal cord trauma;
- complications arise after stroke;
- unbalanced nervous system;
- children's hyperactivity;
- senile dementia;
- poor blood circulation in the brain tissue.
Contraindications
Contraindications Cere include:
- the presence of an allergic reaction to components of the drug;
- severe renal impairment;
- the presence of epileptic seizures;
- first trimester of pregnancy,
- during breast-feeding.
At what age can use the drug
Cere for children, pediatricians and neurosurgeons reviews which indicate that the drug is approved for admission to childhood, unlike other neuroprotective agents was tested through clinical trials, even in newborns.
They confirmed that the drug is completely safe, so he was appointed as the infants and children of pre-school and school age. When using Cere necessary to comply with all the recommendations of children's neurologist.
What is the number of injections needed to be done and their dosages determined by the attending physician, based on the diagnosis carried out by them and the individual characteristics of the child.
Instructions for use, the dosage of the drug
Cerebrolysin be administered intramuscularly, or directly into the bloodstream (vein). If the assigned dose of 5 to 10 ml, the drug is administered intramuscularly without prior dilution solution. If the attending physician prescribes a dosage of 10 to 30 ml, then Cerebrolysin first diluted solution of 5% D-glucose or sodium chloride and then slowly injected into a vein with a dropper.
Keep the solution may be diluted for one day at a temperature not exceeding + 25 ° C. Often the entire period of treatment takes 10 to 20 days. In cases separately prescribed Cerebrolysin administered once a maximum permissible dose - 50 ml of solution.
| The recommended daily dose | testimony |
| from 10 to 50 ml | pathologies arising after the brain surgery, hemorrhagic and ischemic stroke, severe forms of meningitis, brain and spinal cord injuries and their consequences |
| from 5 to 50 ml | traumatic brain injury, and later during the residual stroke |
| from 5 to 30 ml | depression, metabolic disorders, Alzheimer's disease |
| 1 to 2 ml | neurological diseases |
For children up to six months is recommended dosage is 0.1 ml for each kilogram of body weight, though the maximum permissible dose for this age - 2 ml per day.
Treatment generally lasts until healing or significant improvement of the baby's condition. Introduce the drug you need from 1 to 3 times a week. Repeated therapy can be carried out in 3-4 months after the first.
The causes of inflammation after the injection
bump can be formed by properly made the injection. This is a sign of inflammatory reaction.
The reason may be:
- an allergic reaction to the drug;
- too rapid administration of the drug;
- clenched muscles;
- of infection;
- incorrect storage solution at conditions;
- damage to the blood vessel;
- a thin needle is not enough;
- trauma of the nerve ending.
How to ease the pain after the injection Cere?
After the injection pain may occur, which helps to get rid of drawn mesh or iodine attached cabbage leaf. It possesses analgesic properties due to it contains vitamins of group B. Relieves burning and itching.
It will also be effective ointment Vishnevsky and Troxevasin, but you can replace the usual children's ointment. To avoid pain, you must first make a gentle circular motion massage.
If at the injection site was formed to run up a pine cone, then it will help eliminate the aloe. Sheet need to grind, roll up in gauze and apply to the site of the abscess. For maximum effect, the procedure is repeated 2 times a day.
Less effective agent is compress. It may be made of salted cucumber, banana peel, crushed fresh cranberries, honey or raw potatoes. Hold compress need for 10 min.
Side effects
During studies Cere adverse effects were found.
The list of possible adverse reactions while taking the drug:
- chills;
- fever;
- anaphylactic shock;
- depressive personality disorder;
- detached state;
- Twilight confusion;
- disturbance of sleep patterns;
- epilepsy;
- frequent spasms and convulsions;
- pain in the head and neck;
- dizziness;
- limb tremor;
- hypertension and hypotension;
- pain in the heart;
- violation of the rhythm of heart beat;
- heart palpitations;
- dyspnea;
- pain in the chest;
- loss of appetite;
- frequent retching;
- prolonged constipation;
- heat;
- runny nose;
- cough;
- skin redness at the site of injection;
- fatigue.
Overdose
Cerebrolysin overdose cases, as well as its negative impact on the body had not been identified.
special instructions
Dizziness, fever, and sweating may occur if too quickly to introduce the drug into the bloodstream. The solution must be entered as slowly as possible.
Cere is permissible to combine the following standard solutions for injection:
- 0.9% sodium chloride solution;
- Ringer's solution;
- 5% dextrose (glucose) solution.
Cere for children, neurosurgeons reviews which show that during the passage of drug treatment can be combined with a vitamin complex, it involves the use of a medicine necessary for the normalization of the heart circulation.
However connect solutions in one syringe unacceptable. The manual says that only once, you can use the clear essence of the drug.
Requires intramuscularly or intravenously solution immediately after an ampoule or vial were dissected. Studies of the drug showed that it does not affect the ability of the transport management and use of the mechanisms.
drug interactions
Cerebrolysin can not be combined with the administration of drugs containing lipids. Allowed to use on the treatment solution together with vitamin complexes, as well as the means necessary for the treatment of heart disease and diseases of the vascular system.
The preparation enhances the effects of antidepressants and monoamine oxidase inhibitors.
analogs of Cere
Cere analogues are:
- Aminalon;
- Vazavital;
- vinpocetine;
- Kognifen;
- Cortexin;
- Lutset;
- Memozov;
- Neuro-law;
- Neyrovin;
- Neyrodar;
- Neyrokson;
- Neyronika;
- Noobut;
- Noozam;
- Noopept;
- Nootobril;
- nootropil;
- Noofen;
- Oksopotin;
- Olatropil;
- Omaron;
- Pantogamum;
- Pantokaltsin;
- pikamilon;
- piracetam;
- Piratsizin;
- Pramistar;
- semaks;
- Somazina;
- Somakson;
- Tiotsetam;
- Fezam;
- Phenibut;
- fenotropil;
- Tserakson;
- Tserebrokurin;
- Tseregin;
- Tsizam;
- Tsinatropil;
- citicoline;
- Evrizam;
- entropy;
- Encephabol.
Terms, conditions of sale and storage
Date of manufacture is indicated on one side of the original packaging of the drug.
The shelf life of the drug are:
- 5 years in ampoules;
- 3 years in bottles.
Use tool for 15-20 days prior to the end can only be under the supervision of a specialist. However, to apply Cere after ended storage time is not recommended.
After opening the vial and the vial should be used immediately Cere and its remnants disposed of. If you store the drug in the wrong conditions, the sediment at the bottom of vials appears, and therapeutic efficacy will decrease. After the appearance of the sediment and discoloration Cerebrolysin solution to the use of non-negotiable.
Store Cerebrolysin need at room temperature which does not exceed + 25 ° C. Keeping the solution in the freezer, then it can not be heated. The drug is spoiled by contact with ultraviolet rays, so it must be stored in a dark, dry and out of reach of children.
In pharmacies and medical institutions drug should be stored in their original packaging near the medium-analogues. After the expiry date, or when a defective product is removed from the sale and transferred to specialized services, waste disposal pharmacological agents. The drug is released at a pharmacy without a prescription.
Price in drugstores of Moscow, St. Petersburg, regions
The cost of the drug depends on the amount of ampoules or vials, as well as by their number in multiples.
The average price of Cere in Moscow, St. Petersburg and the surrounding regions:
- Packing 5 ampoules each of 5 ml, costs 1 000 rubles.
- Packing 10 ampoules, each 2 ml, costs 1 000 rubles.
- Packing 5 ampoules, each with 10 ml costs 1 500 rubles.
- Packing 5 ampoules, each of 20 ml, is 3 000 rub.
Advantages and disadvantages of the drug
The main advantage of Cere - efficiency. The drug improves blood circulation in the brain, eliminates insomnia, improves memory, protects neurons from oxygen starvation, and performs many other of its functions. The therapeutic effect is retained up to 6 months.
In addition, it is important that the drug is allowed and safe for the treatment of children. It stimulates the development of speech in children with developmental delays, as well as a high efficiency due to birth injury.
The disadvantages are the high cost of Cere and the risk of adverse reactions. Also, the drug is not available in tablet form, which complicates its use. For the administration of the solution will need to visit a clinic or call the employee medical facilities in the house.
As Cerebrolysin affect sleep?
Despite the fact that its characteristics Cerebrolysin has a positive effect on sleep, its main side effect is insomnia. After a few doses of the child may become too excited, which will lead to sleep disturbances.
You can restore it to start taking medication, have a soporific effect. Assign them can only physician after further diagnosis and delivery of analyzes. Refer to those skilled necessary at the first occurrence of insomnia.
Its symptoms include poor concentration, aggression, hyperactivity, early rises, as well as fatigue and drowsiness throughout the day.
Often prescribe medications such as:
- melatonin;
- antihistaminergic drugs;
- benzodiazepine hypnotics;
- trazodone;
- mirtazapine;
- imipramine;
- l-5-hydroxytryptophan;
- chloral hydrate.
Cere among peptidergic nootropic agents, real, about which clinical analyzes, prove that they are approved for the treatment of children, support and stimulate the development and activity neurons. Due to such properties, Cere able to stop or greatly slow down the damaging and destroying brain cells, processes.
Registration of the article: Mila Friedan
Videos about cerebrolysin
Elena Malysheva tell about cerebrolysin:
