Combilipen injections. For what is prescribed, instruction manual intramuscularly with cervical osteochondrosis, psoriasis, spinal hernia, anemia, hair loss, diabetes, oncology. Price 5, 10 vials, analogs, reviews

Combilipen - a drug comprising a combination of neurotropic (positively affecting the nerve structure) vitamins of group B. Injections are administered to accelerate the restoration of nerve tissue, and reduce / eliminate the sensation of pain when inflammation or injury of neural tissue or the musculoskeletal system.

The composition of the injection

1 ml injection solution contains active ingredients at the indicated doses:

• 0.05 g of thiamine hydrochloride (vitamin B1) - in conditions of deficiency of vitamin impossible to conduct adequate neyroimpulsa, no less important role in ensuring the connection of the metabolic processes (protein, fat, carbohydrate metabolism);
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• 0.05 g pyridoxine hydrochloride (vitamin B6) - It plays a role in hematopoiesis and nerve supply glucose cells needed for functioning of the liver. The substance promotes mental capacity, improves memory and mood;
• 0.0005 g of cyanocobalamin (vitamin B12) - important for the production of acetylcholine, ensuring the conduction of nerve impulses. The substance supports blood composition (improves quality and resistance to the disintegration of red blood cells - red blood cells). B12 is involved in the production of vitamin B9, and the myelin sheath of nerve cells, increases the potential for tissue growth and repair;
• 0.01 g of lidocaine hydrochloride - "suspended" active ingredient that reduces the injection pain and promotes rapid absorption of the "vitamin" components.

The composition also includes auxiliary components introduced to disinfect and stabilize the structure of the solution, and the water (to volume).

release Form

For injection of the agent must be purchased in the form of vials. One ampoule of dark glass contains 2 ml injection solution - this should be taken into account by counting how many vitamins go into the body (at the previously specified composition 1 ml).

The contents of the vials - clear liquid pinkish raspberry color with a strong odor.

Each contour pack contains 5 or 10 of sealed cells. A pack of cardboard includes 1 or 2 circuits packaging on application management.

therapeutic effect

The solution for injection comprises a combination of 3 components vitamin plays an important role in the human body. In particular, they are indispensable for the proper functioning of neyrostruktur.

The introduction of intramuscular vitamin rescues get the next range of therapeutic effects:

• maintenance of metabolic reactions, including in the central nervous system;
• improving hematopoietic function - red blood cells mature faster and better resist decay;
• normalization of the central and peripheral nervous system;
• accelerate regeneration of the myelin sheath of nerve cells and specialized neyrostruktur;
• Stabilization of neyroimpulsa (by increasing choline products - raw material for the compound control pulse transmission), and the drive and braking mechanisms in the central section nervous system;
• create conditions for the synthesis of catecholamine hormones (epinephrine, norepinephrine) without which can not be adequately organism adaptation to stress conditions, significant physical and emotional stress;
• protection of nervous structures of the toxic lesions.

Combilipen injections (which prescribers will be described later) differs from the tablet form appreciable and rapid analgesic effect (reduced srednevyrazhennye pain). In addition to its analgesic action Combilipen enhances the analgesic properties of nonsteroidal anti-inflammatory drugs (at reception in the complex).

Indications

Injections Combilipen (according to the official guide and reviews patients) administered together with other drugs in monotherapy or in pathologies.

They are as follows:

• trigeminal neurological pain - intense attacks in the region of the trigeminal nerve (one of the causes of the violation is considered to be the loss of nerve roots of the myelin sheath);
• inflammation affecting the facial nerve (neuritis) - often in combination with other drugs FarmGruppa;
• polyneuropathy - including emerging diabetes mellitus or ethanol intoxication;
• pain syndrome in diseases of various departments of the spine: torakalgii (chest pain during compression of or damage to the intercostal nerves); lumbar, cervical and cervical-brachial syndrome (nerve compression in the respective zones); radiculopathy (damaged spinal roots); degenerative (associated with the death of neurons due to injury or systemic disease) changes in the spinal column.

In addition to basic reading means is recommended in patients with:

• heel spur (plantar fascia);
• nervous exhaustion, nervousness, asthenic conditions;
• chronic stress;
• lowered immunity.

Doctors prescribe medicament for stimulating recovery after acute (stroke), severe inflammation (e.g., in gynecology) or surgical intervention.

Instructions for use

Combilipen injections (for which the drug can be administered by a doctor clarified) effective provided that the dosage, mode and localizer administration nuances. According to the instructions in the presence of appreciable pain recommended administered 2 ml (1 ampoule) intramuscularly per day. The course - 5-10 days.

After completing the course of injections, there are two options for extending therapy:

• switching to another drug in the form of release (tablets) - reception Combilipen Tubbs;
• schema change and dosage: 2-3 is required to carry out the injection in the last 7 days, the course - 2-3 weeks, after which it also follows the transition to pelleted medication.

In uncomplicated cases recommended to be administered to 2 ml 2-3 times a week for 7-10 days.

Make the process of the introduction of minimally painful and avoid compaction at the injection site will help compliance with these recommendations:

1. The solution must be stored in the refrigerator, it is permissible to warm a vial in her fingers just prior to administration.
2. Injections optimally put into the outer upper part of the gluteus maximus. However, if the patient has the skills and perform the injection itself, it is best to introduce the solution into the anterior third of the outer surface of the femur.
3. Before be treated stab the desired area of ​​the skin with an antiseptic solution - alcohol or chlorhexidine.
4. Cannulate be vertically until it stops. Deeply enter the drug will help purchase a syringe 5 ml - it comes with a long needle.
   
5. The drug should be administered slowly.
6. It is necessary to try to get between places where the injection is carried out, there was a distance - not less than 1.5 cm.

In the absence of experience or skills, it is desirable to do injections in a health institution. If by chance there was intravenous drug requires medical supervision and, if necessary, eliminate the identified symptoms.

For children

The drug is not recommended for use under the age of 18 years due to lack of data on clinical trials in this age group. Another reason not to apply the agent in children is included in the benzyl alcohol solution.

For pregnant women and during lactation

According to the official guide, a drug in an injection is contraindicated in women during gestation and breastfeeding. Thiamine hydrochloride and pyridoxine hydrochloride are able to penetrate into breast milk, while B6 is able to slow down its production.

Side effects

Combilipen injections (which prescribe the drug described above) contain large doses of vitamins and can cause a number of side effects.

Among the negative effects of these instructions:

• increased heart rate;
• labored breathing;
• rash acne type;
• allergic itchy skin and dermatitis;
• sweating;
• Angioedema;
• anaphylaxis.

According to reviews, the most often cited aknepodobnye lesions of varying severity, rarely - palpitations and sweating.

Patients who have used the drug in the form of injections, also note:

• hot flushes to the head and face;
• pain in the head;
• Blood pressure drops;
• stomach discomfort;
• disruptions in the functioning of the gastrointestinal tract (constipation);
• excitement (why injections is preferable to put in the first half of the day);
• seals and bruising at the injection site (can be linked to the introduction of a violation of the process) - for effective removal Troxevasin.

People who is assigned the first time a drug, it is desirable to perform a first injection in the outpatient settings.

A significant proportion of allergic reactions due to the presence in the composition of lidocaine, however often the problem is solved for this analog without anesthetic (e.g., Neyrobiona).

Contraindications

Combilipen injections (for which the medicament is prescribed, it is possible to read the instructions and on the Internet) include only vitamins (in high therapeutic doses) and lidocaine.

Therefore, the list of absolute contraindications to the use of this form of release is relatively small:

• acute and severe heart failure decompensation;
• during gestation and lactation;
• age of 18 years;
• hypersensitivity to primary or secondary components in the composition of the injection mold;
• Parkinson's disease (the appointment is inappropriate).

Use of the drug is possible with caution in:

• malignant processes;
• diabetes;
• inflammatory diseases of the liver;
• serious disorders of the nervous system.

special instructions

During the course of treatment is not recommended to use injection multivitamin complexes containing vitamins of group B.

Overdose

Introduction of excessive doses of drugs can provoke the increased side effects of medication.

Can develop:

• dyspepsia - nausea or vomiting;
• dizziness;
• profuse sweating;
• increased frequency of contractions of the heart muscle;
• allergies of various types (itchy rash, subcutaneous edema).

If there is a violation of dosing and the appearance of symptoms should implement the following measures:

• gastric lavage;
• reception absorbents (enterosgel, activated charcoal);
  
• elimination of symptoms (using external ointments, antiemetics, sedatives).

Interaction with other drugs

Most of the restrictions on a combination of the solution with other medicines dictated by the properties of vitamin components in the formulation.

In particular:

• Vitamin B1 is destroyed when mixed with substances having an oxidizing or reducing ability: mercury salts - hydrochloric, carbonic, acetic acid, mercury iodides; ferric ammonium citrate or iron; tannic acid;
• application can not be combined with B1: phenobarbital; Vitamin B2; sodium metabisulfite; benzylpenicillin; dextrose;
• inappropriate assignment vitamin B1 with sulfites (for injection solutions Tetracycline, Doxycycline, Monotsiklina - they all contain sodium disulfite);
• B1 is capable of being ruptured upon contact with copper, as it is inactive in a medium at pH greater than 3;
• when used in conjunction levodopa therapeutic effect of vitamin B6 reduced;
• Vitamin B12 can not be combined with salts of heavy metals and vitamin C, the damaging effects it exerts vitamin B2, particularly in the presence of bright light;
• forbidden to accept any simultaneously complexes containing vitamin B, epinephrine and norepinephrine drugs;
• the drug may interact with isoniazid, penicillamine and cyclosporin - exact figures are not presented on compatibility.

Combination of vitamins capable of enhancing the analgesic effect of NSAID (Diclofenac, Movalis, Voltaren).

Interaction with alcohol

Simultaneous use of drinks containing ethyl alcohol is highly undesirable. Ethanol can significantly decrease the absorption of vitamin B1.

Storage conditions

The ampoules should be stored in a dark place, out of reach of children. Temperature range - from 2 to 8 degrees (in a refrigerator). Subject to the drug storage conditions can be used for 24 months from date of manufacture.

The price of the drug

Injection Combilipen - a prescription drug.

The cost depends on the number of vials in the following package:

• 5 ampoules - 190 rub .;
• 10 vials - 280 rubles.

Buy medication can be in an online pharmacy or pharmacy chains. Among the "rare" does not apply medication.

analogs

Among similar in composition to the drug analogues are preparations in the form of injectable solutions or tablets. Since the pelletized form provides less pronounced analgesic effect, the table provides information about analogues in ampoules.

Table:

Name of analogue	Efficiency	Features of the application	approximate cost
milgamma	Indications for use are similar to Kombilipenom and "officially" include ganglionitis (inflammation ganglia) and cervical osteochondrosis. According to the doctors and patients, the fundamental difference between the action and Milgamma Combilipen not, although some patients still prefer milgamma. The composition and the side effects are similar to Kombilipenu.	Medication is contraindicated in children under 16 years of age, and pregnant and lactating women. We do not recommend the use of alcohol. As with Kombilipenom, there is soreness administration of injections.	5 vials - about 300 rubles. 10 vials - about 500 rubles.
Neyrobion	The same vitamin composition 1 vial readings are almost identical Combilipen. Does not contain lidocaine, therefore, say to the use of people with allergies is a pain reliever	The drug is contraindicated for children under 18 years of age, pregnant and nursing women.	3 vials - about 300 rubles.
Neyromultivit	Composition identical Neyrobion (without lidocaine).	Neyromultivit is contraindicated in children under 18 years of age, pregnant and nursing women. A number of patients report significant pain injections.	5 ampoules - 200 rubles. 10 vials - 390 rubles.
Vitakson	Composition similar Kombilipenu comprises lidocaine	The drug is contraindicated for children under 18 years of age, pregnant and nursing women.	5 ampoules - 200 rubles.

Despite the completely identical composition, efficacy and tolerability of these drugs in different people (reviews confirm this) may differ slightly.

medication has a powerful restorative effect on the body, relieve pain in traumatic and inflammatory diseases the nervous system. The drug accelerates recovery after surgery or severe inflammation.

Injections Combilipen prescribed for use in conjunction with non-steroidal anti-inflammatory agents, increasing their effect. However, large doses of vitamins and lidocaine can lead to side effects, the most common of which - acne. In some cases the problem can be solved with the help of analog drug.

Registration of the article: Lozinski Oleg

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