Pancreatic amylase, the rate of which may vary depending on what the laboratory analysis was carried out, is an indicator of pancreatic health. The difference in the resulting research data from different diagnostic centers is due to an error of the equipment by means of which the analysis of, and the method of splitting. To avoid confusion, index near each laboratory analysis indicates a rate of amylase.
Amylase: summary and performance standards
Pancreatic amylase - what it is and what its role in the body, it is possible to know if a bit familiar with how to operate human organs and systems.
For the processing of carbohydrates, including starch and glycogen needs a special enzyme, which is an amylase. Its major amount (an enzyme) is concentrated in the pancreatic juice and salivary glands. Pancreatic juice moves in 12-duodenum. There splitting process begins. As a result of its formation:
- polysaccharides;
- glucose;
- maltose.
Conclusion amylase is excreted by the kidneys is carried out, i.e., the remains of the enzyme excreted in the urine.
Is the norm when a small amount of the substance contained in the intestines, ovaries and musculature.
Depending on the purpose for which diagnosis is carried out, to obtain the most accurate information, you may need to analyze blood and pancreatic amylase enzyme in the percentage of urine.
Alpha-amylase or P-amylase (such values may be indicated in the medical record) is measured in units per liter. Index rules enzyme in the blood depends on the age of the test:
- in children under 1 year - 8 U / L;
- from 1 year to 10 years - no more than 30 U / L;
- from 11 to 18 years old - no more than 40 U / L.
The norm in adults, whose bodies are considered to be fully formed after 18 years, is 0-53 U / L. In the normal range in the urine amylase is 20-100 U / l. The norm for women and men about the same.
In more detail to find out what it means when the enzyme level is not correct, you can have your doctor individually.
increased rate
If the pancreatic amylase in the blood increased, but the content of the enzyme in the saliva is correct, it can be the assumption that the test there is a disruption in the work of the pancreas or the pathology is localized in the near arranged organs.
The causes of excessive accumulation of the enzyme in the blood may be as follows:
- Acute pancreatitis. The disease is characterized by inflammation, which has a bright symptoms. Pain syndrome localized in the prostate area and radiates to the back. In addition, symptoms of intoxication. Amylase in pancreatitis acute form is able to exceed the norm in a few times, but not always. In the case where the body is severely damaged, which is accompanied by a significant loss of cells that produce this enzyme, its rates are changing little. To ensure the correctness of the results of laboratory studies, patients with suspected pancreatitis, it is recommended to analyze the activity of lipase. The importance of this enzyme in lesions of the prostate remains always high. (Lipase - Compound of protein molecules, which catalyzes the hydrolysis of esters-insoluble lipid substrate using, enabling the body to digest fats).
- The chronic form of pancreatitis. Characterized by a gradual increase in the figures of amylase. With long-term course of the disease there is a decrease of enzyme to normal.
Lipase is within the normal range when its index in patients under the age of majority is 0-130 U / ml. For adult men and women in the blood level of enzyme can range from 0 to 190 units / ml of blood.
Lipase is not always increases under the influence of pathological processes that occur in the digestive tract. The value can be changed in patients with fractures of the tubular bones.
When pancreatic amylase increased, its accumulation in the blood due to the addition of the enzyme to the bulk proteins. The process of discharge of the substance in the ducts becomes problematic. The causes of this abnormal process may be as follows:
- pancreatic duct blockage;
- a tumor in a body sections;
- bowel obstruction;
- bundle of aortic aneurysms;
- stone formation in iron;
- diabetes;
- acute appendicitis;
- cholecystitis;
- hepatitis;
- inflammation of the peritoneum;
- abortion;
- abdominal trauma or perforation of the ulcer;
- makroamilazemiya.
Lowering index amylase
When amylase is lowered, then theoretically, this indicator should indicate that the patient has no health problems. In this state, the pancreas should be fully operational.
But the reality is somewhat different.
In most cases, against the background of a reduced amylase in the patient can be diagnosed following pathologies:
- pancreatic cancer in the late stages.
- Total pancreatic necrosis. Extensive body destruction at the destructive acute pancreatitis.
- High cholesterol.
Reduction of amylase in the blood is characteristic of patients with most of the cancer was removed. Not excluded and congenital causes abnormal processes that are caused by the body structure disorder and improper functionality. Pathology can be inherited.
conclusion
Blood amylase to pass from a vein. Appointed this analysis not only suspected the existence of pancreatitis. It can be used to confirm or deny the presence of a pathological process in the ovaries or deviation in the salivary glands.
To obtain reliable results of laboratory studies, patients need to prepare themselves properly. Some drugs, alcohol, smoking and other factors, more about which will tell a specialist, can distort the performance level of the enzyme.
To find out why the level of amylase differs from the norm, the patient will be assigned additional tests. Kind of research is chosen based on the individual patient's clinical picture.
should not give up on medical advice. Early treatment will prevent progression of the disease.
