No-spa - a drug, has antispasmodic and sedative effects. Its action is aimed at the smooth muscles of the bodies. To some extent Nospanum effect on vessel walls, facilitating their expansion.
The result is a marked hypotensive effect. But the influence of the drug on blood pressure appears to a small extent. Therefore, it is not included in the list of drugs intended for the treatment of hypertension. Nospanum at high pressure is appointed often enough, and its reception should be carried out under the supervision of a physician.
Indications for use
Nospanum used as an antispasmodic action quickly. Indications for drugs are:
- muscle and intestinal cramps;
- kidney stones;
- brain and vasospasm;
- elevated blood pressure.
Nospanum hypertension can reduce blood pressure. It dilates blood vessels and stimulates blood circulation. All this leads to a reduction in the basic symptoms. The most effective formulation exhibits, if the cause of the disease is vascular spasm.
Contraindications
Despite the high efficacy of the drug, it has a number of contraindications. Among them are:
- renal failure;
- liver disease;
- poor vascular permeability;
- intolerant individual components of the formulation;
- adenoma of the prostate gland;
- lactation in women;
- cervical incompetence during pregnancy;
- glaucoma;
- cerebral atherosclerosis;
- up to 6 years;
- some cardiovascular diseases.
The drug can normalize pressure at hypotension. Its use in such cases should be with caution.
How does
The main active ingredient is shpy drotaverine hydrochloride - isoquinoline derivative having an antispasmodic action. It extends to the smooth muscle fibers of the biliary tract, gastrointestinal tract and the uterine myometrium. The hypotensive effect of the drug is ensured suppression fermentarnoy fourth type phosphodiesterase function. On the myocardium and blood vessels, which dominates the third type enzyme, a drug affects weaker.
Drotaverine lowers blood pressure and shows high efficiency in both muscle spasms nervous and muscular nature, regardless of its autonomic innervation.
The substance has the feature of binding to serum albumin and alpha beta globulins. Moreover, its maximum concentration in plasma is approximately one hour after oral administration.
Nospanum reduced pressure and compared with papaverine, does not lead to stimulation of respiration acting as a side-effects after parenteral administration.
How to apply in different forms
Nospanum from a high pressure can be applied in two forms: tablets and solutions for injection.
For oral use of achieving the effect of the drug occurs slower than after intravenous or intramuscular administration, when the drug immediately enters the bloodstream.
Dosage doctor chosen individually in each case.
At elevated pressure Nospanum take 1 tablet 4 times a day. In the absence of treatment result can be repeated at hourly intervals between doses of the drug. Maximum daily quantity of the main active substance - 200 mg.
Exceeding this dose leads to an overdose Drotaverinum, which is fraught with the development of side effects: heart pulse conduction abnormalities, arrhythmia, bundle branch block and complete stop heart.
With moderate disease the drug is prescribed intramuscular, acute - intravenous. The dosage for adults can vary from 40 to 240 ml per day.
In the acute form of hypertension is introduced 80 ml of intravenously. Manipulation carried out in a hospital, under the supervision of a physician.
With hypertension, in addition to shpy should have on hand, and other drugs for normalizing the blood pressure. In addition, it is recommended to comply with a special diet, drinking regime and often walk in the fresh air.
