Platelets - tiny blood cells. Everyone should know where platelets are produced and what function they perform.
The role of cells in the body
These particles serve an important role in the formation of fibrin, the oxygen supply of the organism tissue, maintain immunity. The cells function as blood clotsFrom their number depends on the speed at stop bleeding wound. When a person is scratched, these particles begin to break down and attached to the injured blood vessels, restoring them and rolling the blood.
Such process is called platelet aggregation. Human organs, which are destroyed leukocytes and platelets are subject to inflammation. Blood cells activate the immune system, it eliminates the inflammatory focus.
What body produces
Platelets produced by the bone marrow. First formed in humans megakaryoblasts that creates a mesh cage. Then there is its maturation, distribution, size reduction and separation of the particles from it mature.
They do not have nuclei, but the cytoplasm is a plurality of beads with substances that promote the formation of blood coagulation factors. Their main function - the development of processes for the attachment of the erythrocytes in the formation and consolidation of a blood clot. The life cycle of these particles is from three to six days. They dissolve in the epithelium of blood vessels and spleen.
There are two stages of blood coagulation:
- The cell, which is performed platelets. They form a substance which draw red blood cells to the site of thrombus formation and isolated components necessary for clotting. After the cells perform their function, the second stage begins.
- The protein, at which appear and move to the place of rupture artery blood clotting factors and thrombus is formed. Their activity depends on the quantity, volume and the presence of chronic diseases in the body.
Aggregation of these particles is an important indicator for the assessment of the coagulation system. Rate of aggregation can be determined in the laboratory. Platelet cells are formed in order to induce processes of tissue repair and regeneration.
where are destroyed
To stop the bleeding, platelets are destroyed and die. Due to the viscosity of the blood creates a buffer that holds the blood inside the vessel. This work is carried particle data. They are in a state of readiness and can quickly fulfill their role in the event of the threat of loss of blood. Due to the large amount of accumulation of the particles occurs near the vessel walls. Inside the vessel is a shell consisting of endothelium.
If a person has no violations or damage, the particles produced by the endothelium. Due to this blood moves on branching vessels. Damage to the vessel immediately respond to such blood components.
Their activation occurs under the following conditions:
- changes in the vascular endothelium;
- atherosclerosis;
- inflammation;
- Excessive formation of clotting liver cells;
- severe diseases which are accompanied by intoxication.
Included mechanism when they not only tend to restore the damaged vessel, but also to maintain the desired viscosity and allow circulation at high viscosity. This is their primary role.
Circuit activation and generation of data cells in the body is as follows:
- adhere to the site of injury to the vessel;
- change their shape;
- on their surface occurs plurality of processes;
- they create the shape of a star;
- increases their area.
The cells accumulate at the site of vascular injury, while creating a conglomerate, which settles fibrinogen. It interacts with the cells and forms the final clot that stops blood loss. The corpuscles are mitochondria, which provide cells with energy through redox reactions.
Mitochondria need for rapid destruction. Platelet aggregation runs a chain of processes that lead to their transition in excess of the activated state. Mitochondria were collected and accumulate calcium, when its concentration becomes higher than the critical level, starts the process of destruction of platelets. Sloshing occurs calcium and oxygen from mitochondria. cell skeleton is destroyed, its volume increases. On the outer membrane of the enlarged object arises lipid which contributes to the rapid clotting.
The blood test data on the amount of particles in the body required to pass regularly to identify them and prevent the occurrence of a shortage of various diseases. platelet formation - an important process in the human body, which affects the proper functioning of many systems.
