Lowering atherogenic factor within acceptable norms among adults has no clinical significance and does not require medical intervention. This condition can be caused by physical and nervous exhaustion, wrong chosen diet or hormonal therapy. But in children decrease in this indicator leads to serious disruptions in the body and requires a mandatory correction.
The content of the article:
- 1 The essence of atherogenic
- 2 The principle of forming lipid atherogenic index
- 3 The norm in women over the age of
- 4 This analysis shows renting
- 5 How to prepare for analysis
- 6 How is the analysis of how much to wait for results
- 7 Calculation of the index (formula), deciphering
- 8 The reasons for lowering
- 9 Causes of high atherogenic
- 10 Reasons for inaccurate analysis
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11 How to reduce atherogenic factor
- 11.1 Diet
- 11.2 Modifying lifestyle
- 11.3 The use of medicines
- 12 Power at reduced level
- 13 Forecast for life
- 14 Video of atherogenic factor
The essence of atherogenic
Cholesterol is a fat-soluble alcohol, being in the body only in the bound state in the form of lipid-protein complexes called lipoproteins. In the body, 80% of the required cholesterol produced in the liver, small intestine, adrenal gland, skin and gonads. And only 20% comes from food.
The following types of lipoproteins:
- "Bad" lipoproteins and very low density capable precipitate;
- "good ones" antiatherogenic high density lipoproteins providing cleansing walls of blood vessels from cholesterol seals.
The term "atherogenicity" refers to the ability of lipoprotein intermediate, low and very low density deposited on the inner walls of blood vessels. At higher concentrations of such "bad" cholesterol is the formation of cholesterol plaques hindering normal blood circulation. Itself increase the spacecraft does not prove the presence of cholesterol deposits.
But in the long term it can cause:
- blood clots and complete blockage of blood vessels;
- coronary heart disease;
- stroke;
- myocardial infarction;
- cerebrovascular accident;
- appearance trophic ulcers on the legs, emerged as a result of severe disturbances of blood circulation in the peripheral vessels;
- stop necrosis;
- development of pathology of the internal organs to hypoxia.
The principle of forming lipid atherogenic index
To calculate the index (index) atherogenic performed laboratory investigations to determine the amount of LDL and high density. Their total amount is called total cholesterol (TC).
The higher the NA, the more disturbed the balance between useful and harmful lipid complexes. From this data, the specialist can suggest the development of atherosclerosis in a patient and prescribe additional tests.
The norm in women over the age of
With age atherogenic factor changes.
For women it is:
- from 20 to 30 years - 2.2;
- from 31 to 40 years - 1.88-4.4;
- from 40 to 60 years - to 3.5;
- more than 60 years - 3.5-4.0.
If a woman over 40 years of developing coronary heart disease, is a valid CA is reduced to 3.2. In men, this figure is higher than that of women in the 0.3-0.5 units. But at the same time representatives of the stronger sex are more prone to the formation of cholesterol plaques and atherosclerosis.
This analysis shows renting
Atherogenic factor is lowered can be professional athletes, women, sitting for a long time on low-cholesterol diet, as well as in patients undergoing hormone therapy. Most often it is a specimen collection only in depressive disorders or excessive weight loss.
Athletes atherogenic index check is performed to correct the power, graphics and strength training. In most cases, the doctor prescribes an analysis for suspected increase in this indicator.
The risk group includes persons:
- obese diabetes, physical inactivity, high blood pressure;
- standing registered a cardiologist;
- having a genetic predisposition to the development of atherosclerosis;
- abuse of alcohol;
- smoking;
- Stroke or heart attack.
Regular monitoring of indicators of atherogenic index held under long-term course of diet therapy in patients with significant obesity. This allows you to track the dynamics of reducing the amount of cholesterol "bad" and to amend the diet if necessary.
Patients with a genetic predisposition to clogged blood vessels, experts recommend to pass the first examination at the age of 9-11 years. Further, it should be repeated in 19-21 years, followed by a regular delivery of analyzes 1 every 5-6 years.
How to prepare for analysis
Atherogenic factor may be lowered due to improper preparation for delivery of analyzes. Distorted figures do not give an opportunity to quickly identify the problem and proceed to its elimination.
Therefore, you should adhere to the precise instructions of specialists:
- A week before the survey can not change the diet and sharply limit the intake of foods containing cholesterol.
- If possible, 3-4 days to abandon or significantly reduce the intensity of exercise.
- 3-4 days to stop the consumption of alcohol beverages.
- For 12 hours prior to manipulation stop food intake and liquids containing sugar and its substitutes.
- 6 hours before the test to stop smoking.
The presence of inflammation in the body distorts the content of lipoprotein parameters. Therefore, a malaise or fever should be reported to your doctor and arrange to reschedule a survey.
Also, the expert must provide a list of accepted medicines. He will decide whether the termination of their admission for a short time in order to obtain reliable results.
How is the analysis of how much to wait for results
To identify the level of blood cholesterol is carried out sampling from a vein. Manipulation is carried out on an empty stomach in the morning from 7.00 to 10.00 after a full sleep and the absence of stress. Competent experts pay special attention to this issue and do not appoint people to inspection after the night shift.
Directly to the patient in the study offer to sit down, catch your breath and heartbeat.
To investigate selected from 2 to 5 cm3 blood in a sterile tube, label it, and sent to the laboratory. The result is given within 24 hours.
Calculation of the index (formula), deciphering
atherogenic factor represents the ratio of "bad" and "good" lipoproteins.
It is expressed by the formula SV = (TC-HDL) / HDL, where:
- SC - coefficient of atherogenesis;
- TC - Total cholesterol;
- HDL - high-density lipoproteins.
The reasons for lowering
atherogenic factor is lowered in adults for the following reasons:
- exhaustion;
- significant physical exertion;
- long diet with a minimal amount of fat;
- severe emotional stress;
- Women receiving hormonal uncontrolled preparations containing estrogens;
- treatment with antifungal drugs;
- long-term use of statins and drugs on the basis of erythromycin.
Children reduction in atherogenic levels caused primarily by the consumption of inadequate amounts of lipids. But, in contrast to adults, a child's cholesterol shortage negatively affects the brain, resulting in poor digestibility of the information received and the lag in school. Girls KA provokes low delay puberty.
Lack of cholesterol in children provokes the psycho-emotional disorders and increases the risk of committing suicide. Also, a failure occurs in the gastrointestinal tract due to lack of bile acid synthesis in which cholesterol is actively involved.
Causes of high atherogenic
High atherogenic factor due to the following factors:
- lack of exercise;
- obesity;
- genetic predisposition to stroke, varicose veins, heart attack;
- resistant hypertension;
- diabetes;
- in the presence of excessive amounts of dietary fat animals;
- smoking;
- frequent consumption of large quantities of alcoholic beverages.
Men and women over 45 years are the cause of high atherogenic hormonal changes and slowing of metabolic processes in the body.
Reasons for inaccurate analysis
atherogenic factor is not constant and depends on many factors:
Factors that trigger false positive result | Factors that trigger false-negative result |
Pregnancy | Vegetarianism |
Smoke analysis before handing | Blood donation in the supine position |
A fatty meal during the day prior to the examination | Physical activity in assays delivery day |
Blood donation in a standing position | Long-term use of statins prior to the survey |
Receiving steroids | Passage of therapy involving erythromycin drugs at the time of delivery of analyzes |
How to reduce atherogenic factor
To reduce the level of atherogenic requires a comprehensive approach, including a change of diet, avoiding harmful habits and exercise. With a significant increase in performance is assigned to medical therapy.
Diet
Lowering atherogenic factor contributes to the exclusion from the menu of the following products:
- pork, lamb, bacon, meat nutria, ducks and geese;
- meat and liver pate;
- canned meats, sausages, smoked;
- canned fish;
- fat milk and dairy products;
- mayonnaise, butter;
- products containing trans fats;
- confectionery, milk chocolate, candy;
- baked goods made with white flour;
- sugar, jam, ice cream;
- hot chocolate, soft drinks, packaged juices.
Thus it is necessary to enrich the diet:
- rabbit meat, turkey, veal, chicken;
- vegetables, containing no starch;
- greens;
- savory fruits and berries;
- different varieties of rye and wholemeal bread to leaven (without yeast);
- cereals;
- bran, ground flax seed;
- sea fish;
- a small amount of nuts;
- vegetable oils (olive, sesame, pumpkin, flax);
- dairy products with a low percentage of fat.
Do not neglect the fatty fish containing omega-3 unsaturated fatty acids. They are a valuable source of "good" cholesterol, and compensate for the lack of receipt of fats in the body during the diet.
Modifying lifestyle
To accelerate the reduction of the SC and to fix the result of a combination of diet treatment to help with the elimination of bad habits such as smoking and alcohol abuse. Another important factor is the introduction of the date of exercise regime. But we should not just give heavy loads and create stress on the body.
Suffice it to regular walking, light jogging, morning exercise, swimming. yoga under the guidance of a competent instructor will help to improve blood circulation, accelerate metabolism, eliminate congestion in the body. Breathing and energy practices will make it possible to better control their emotions during stressful situations.
The use of medicines
With a significant excess of the level of atherogenic specialist appoints pharmacological agents. Their selection is performed in accordance with laboratory parameters obtained, the individual characteristics of the patient and concomitant pathologies.
Scroll:
- Lipid-lowering drugs (Statins), which include simvastatin and Rozuvostatin. These agents reduce the level of triglycerides and LDL, while increasing the amount of HDL.
- fibrates (Fenofibrate, Ciprofibrate) often prescribed in combination with a statin. Their action accelerates reduction of LDL and the risk of thrombosis, strengthens the walls of blood vessels.
- Bile acid sequestrants (Cholestyramine). They form cholesterol in the intestine insoluble compounds with bile acids, prevents the absorption and accelerate their withdrawal from the gastrointestinal tract.
- anticoagulantsPreventing formation of blood clots by decreasing blood viscosity and blocking generation of fibrin.
- antihypertensiveAssigned to patients suffering from hypertension. Their selection is carried out on an individual basis depending on the severity of the disease and the characteristics of the human body. Normalization pressure minimizes the risk of violating the integrity of the vessels that occurs when occlusion and varicose veins.
- Nicotinic acid (Vitamin B3, Niacin, Enduratsin) used only in the initial stage of atherosclerosis. They dissolve small cholesterol deposits on the walls of blood vessels and normalize blood glucose levels.
In the case where there is blockage of the blood vessels cholesterol deposits, surgical treatment is used. One is the excision of the damaged portion of the vessel.
But there is a less invasive technique:
- bypass, Which creates an additional path for the inflow and outflow of blood bypassing cholesterol plaques;
- stentingBased on the embedding into the lumen of the occluded portion of the metal carcass, which does not allow the artery to narrow the critical diameter.
Avoid surgery will help the timely diagnosis of the disease, properly chosen diet and medicines.
Power at reduced level
Atherogenic factor is lowered more often as a result of long-term unbalanced diet of nutritious substances. Therefore, patients should be encouraged to complement the menu products containing animal fats.
These include:
- fatty meats and fish;
- butter;
- dairy products with medium to high percentage of fat;
- chicken and quail eggs.
Nutritionists insist on the gradual introduction in the diet of this food. This will prevent the creation of a large load on the digestive organs and does not provoke malfunctions of the liver and pancreas. After reducing the parameters to normal, you need to adjust your diet so as to prevent them from fluctuations in the upward or downward.
Advantageously for this purpose should have recourse to the advice of professional nutritionist. Along with the change of power should adjust the intensity of physical activity. This is especially true of professional athletes working to achieve high results and experiencing immense mental and physical stress.
To preserve the health of his players, the coach must develop optimal training schedules and special diets. The only way to keep the spacecraft within acceptable physiological norms.
Forecast for life
Lowering atherogenic factor in adult patients, doctors do not carry serious diseases. This aberration is easily corrected without medication or surgery. Therefore, experts always give a favorable prognosis of treatment, subject to man all the recommendations and regulations.
Video of atherogenic factor
Blood test: bad and good cholesterol: