MCV in a blood test. What it is lowered, raised, norm and deviation in children, women, men

MSV in the blood analysis - is a physiological indicator that displays the average volume of red blood cells. The units are cubic meters. um (micrometers).

femtolitry (fl) may be used as well. According to the results of diagnostics in the laboratory report may indicate macrocytosis, or microcytosis normocytosis. The current result is dependent on the average size of the cells in the bloodstream.

Red blood cells and their function in the body

Red blood cells - a cell unit of blood, the main purpose of which is to saturate the body with all the components of inhaled air. They carry oxygen molecules from lung tissue to the internal organs, as well as other body portions.

In the opposite direction of the red corpuscles excrete carbon dioxide formed after the absorption of air. Oxygen delivery is carried out by hemoglobin proteins, which is 98% of the erythrocytes mass of protein compounds.

By reducing the concentration of hemoglobin is broken transport function of blood cells. Therefore, these indicators should always stay in control.

MCV in blood analysis - what is it?

MCV in blood test - this is the definition of quality indicators of the material. It displays the average size of red blood cells and is included in the list of indicators that are mandatory for identification during the general analysis of blood (KLA).

MCV parameters included in the list of erythrocyte indices. for MCV assay Execution it allows the physician to establish the quantitative characteristics of the state of cells, and then The comparative analysis, to define norms, lack of cellular material or excess of average volume erythrocyte units.

Normal values ​​MCV in adults

MCV in the blood analysis - is an indicator, which tend to change under the influence of age-related changes in the human body, give blood for biochemical research.

Also, the following factors may affect the results of the diagnostics:

• medication, related to the pharmacological group of antidepressants;
• a hearty breakfast before blood donation;
• prolonged alcohol abuse;
• malfunction of medical equipment.

In young men, the optimal parameters MCV is from 80 to 90 fl. For representatives of the female half of the population of normal size red blood cells - is from 80 to 95 fl. In women, the rate of MCV is slightly higher due to the physiological characteristics of the female reproductive system and the monthly blood loss.

MCV age-related changes in adults

MCV in the analysis of blood - this is the definition of quality indicators of blood cell composition, during which takes into account age-related changes in the body. Below are the indicators of erythrocyte indices, are normal for men and women who belong to a particular age group:

Age	Age-related changes in men (unit vials)	Age-related changes in women (unit vials)
From 14 to 18 years	78-94	79-99
From 19 to 45 years old	80-98	82-101
From 46 to 65 years	82-102	83-103
Over 66 years	84-103	84-104

During the execution of the research on the MCV parameters corrected for age-related changes in body tissues, take into account the factor of concomitant disease in the patient under examination, his way of life, working conditions, quality of food, addiction to addictions (alcohol, tobacco, drugs).

With aging

MCV in blood test - this is the definition of quality indicators of the material, which, throughout the life cycle of change, but is not essential. The only thing that can occur in both men and women - a slight increase in the average cell size.

This is explained by the fact that with age, increasing body weight, worsening intracellular metabolism. To ensure more tissues necessary level of oxygen, the body increases the average size of the synthesized red blood cells.

MCV normal values ​​in children by age

At all stages of a child's body there is a change of the parameters of MCV. The table below shows the best performance medium-sized units of red blood cell in children based on age group.

Age	norm level (measurement value fl)
infants	Up to 140
From 1 month. up to 1 year	71-84
From 2 to 5 years	73-85
From 5 to 10 years	75-87
From 11 years and older	80-100

MCV in the analysis of blood - this is the definition of quality indicators of the material, which play a key role in the diagnosis of diseases of the blood in children of all age groups. Therefore, if the child is appointed by the KLA, the selection standards medium-sized red blood cell units is compulsory diagnostic condition.

How is a blood test for MCV

To install the MCV level is necessary to visit a laboratory specializing in the determination of quality indicators of blood, or to hand over analyzes in the district hospital.

For the most accurate diagnostic results with minimum risk of data error, need observe the rules of preparation for the delivery of biological material, undergo blood collection process and wait for the results of the analysis.

Training

It includes the following recommendations, which allow to maintain the cellular composition of the blood at an optimal level without provoking its abrupt changes.

The patient, who will take the analysis requires the following rules:

• 3 days prior to blood sampling is not to drink alcohol;
• pass analysis in the morning of day (preferably to 10-00 hr.);
• 2 days prior to diagnosis to eliminate physical exertion, not to engage in power sports, do not lift heavy objects;
• breakfast only after blood sampling, that the stomach was empty (the best option would be eating wheat, rice, barley, barley porridge with vegetable salad).

During 8 hours. before donation is recommended not to smoke. In the evening the day before delivery of the analysis do not overeat. All food is used before the laboratory study, should be light and not to burden the work of the digestive system.

blood sampling

Prerequisite of delivery of biological material for research on the MCV level is a blood sample on an empty stomach.

This procedure is performed using two methods, namely:

• beam ring finger - automatic pen pierced with needles or a metal lancet (shown in a laboratory is about 1-2 ml of blood);
• ulnar Vienna - sampling biological material is a disposable syringe which is filled with 5-10 ml of blood.

In order to get the most accurate results of the study, it is advisable to carry out simultaneous collection of capillary and venous blood. This will allow a comparative analysis of samples, eliminating the possibility of the occurrence of inaccuracies and errors in the work of the medical equipment.

How long to wait responses

Modern medical equipment allows to receive results of laboratory research on the MCV level for 15-20 minutes.

after passing the biological material. In most cases, determining an average size of erythrocyte units - it is just one of more than 20 parameters blood cell composition which is required to establish the laboratory personnel.

If the clinic staff, where research collected blood using automatic analyzers, the diagnostic process is greatly accelerated.

The laboratories are not equipped with modern medical equipment, and use techniques of microscopic studies will be necessary to wait 1 to 2 hours. In this case, an independent laboratory performs blood analysis, setting the average volume of red blood cells with a microscope.

It is believed that the microscopic method for diagnosis carries a greater number of errors, because here there is the human factor. In order to save personal time and getting the most accurate diagnostic results, it is recommended to donate blood in the laboratories, which are equipped with automatic analyzers.

Deciphering the analysis results

Once completed the study stage biological material and specialist laboratory conclusion drawn from MCV levels display, doctor (or therapist profile hematologist), decrypt medium size options erythrocytes.

comparative study

To provide a comparative study on the simultaneous selection is performed MCV capillary (beam ring finger) and venous blood.

lab specialist puts into both sample analyzer, and verifies the received data on diagnostic results. This method of study makes it possible to eliminate the factor of incorrect operation of the medical equipment and minimize the probability of obtaining a false result.

Reasons for increasing MCV

MCV violation of rules in the direction of increasing the average size of the cells may be indicative of the occurrence of diseases of the blood or point to a pathological condition of the internal organs.

There are the following reasons for the increase in the bloodstream MCV:

• intoxication medicinal antibacterial agents or drugs belonging to the group of antidepressants;

  

• bacterial infections caused by extensive inflammation;
• uncontrolled reception steroids or contraceptives, synthetic hormones;
• severe liver disease as cirrhosis, viral hepatitis or intoxication;
• prolonged use of alcoholic beverages;
• autoimmune diseases, which are expressed in violation of the synthesis process of erythrocytes;
• prolonged contact with chemicals toxic etiology, compounds which blood is saturated;
• deficiency in the body iron and iodine deficiency caused by poor diet or other factors;
• thyroid disease associated with insufficient or excessive synthesis of hormones.

The majority of patients in excess of MCV level standards observed typical symptoms in the form of gratuitous pain in the abdomen, appearance pallor (if present hepatic pathology, the possible yellowing of the skin and whites of the eyes) becomes frequent palpitations, disturbs dyspnea.

At risk are people leading a sedentary lifestyle, as well as having a genetic predisposition.

The reasons for lowering the index

Decrease in the average size of red blood cell units is not less dangerous than the increase in blood cell parameters. The internal organs and tissues of the body begin to experience an acute shortage of nutrients, there comes oxygen starvation of cells and premature death. The man quickly grows thin, develop dysfunction of internal organs and systems.

The reasons for lowering the MCV indicator are the following factors:

• porphyria or hereditary predisposition to the synthesis of defective cells by the body;
• poisoning by heavy metals (often similar clinical picture occurs in people who had contact with the lead pair);
• presence of oncological diseases of the blood or viscera;
• strong dehydration;
• prolonged medication, adverse properties which is a decrease in mean cell volume;
• all kinds of anemia.

People who have downgraded indicator MCV, complain of constant fatigue, decline of physical forces, become distracted, can not concentrate, impaired thought processes.

The nervous system symptoms such as irritability, depression, mood swings, memory loss. When you see these signs must be like to see a doctor as soon as possible.

Classification and causes microcytic (MCV lowered) anemias

Anemia - a group of human diseases of the circulatory system, which is reflected in a decrease in hemoglobin and mean cell volume reduction.

This pathology are classified according to the causative factors that triggered its development, namely:

• allasticheskaya - the system is caused by dysfunction of the bone marrow, resulting in the process of synthesis and maturation of blood cells is disrupted;
• iron - a reduction in hemoglobin production rates, since the patient is not getting enough iron;
• thalassemia - genetic variation anemia, which arises due to the fact that the body is not able to form a sufficiently strong bond in the polypeptide compounds of hemoglobin protein;
• hemolytic - develops when the level of cell death is more than the number of new red blood cells.

Kind of microcytic anemia is taken into account by the attending physician in the diagnosis as well as during the formation of the therapeutic course. Elimination of pathological causes of the disease, is a prerequisite for successful treatment.

cell variability

Under the constant influence of a number of environmental factors, is likely to cause biochemical and physiological adaptations of blood cells.

The variability of mean cell volume is possible under the following conditions:

• prolonged alcohol abuse (alcohol dependence);
• daily contact with toxic substances;
• the use of excessive amounts of protein foods;
• food shortage containing iron and vitamin B12.

Sooner or later, physiological variability cells leads to development of diseases of the blood and tissues of internal organs, who suffered from increased or decrease MCV. Most often, a pathological condition of the cells leads to the development of blood cancer.

MCV correlation with other erythrocyte indices

At the time of determining a prerequisite MCV blood test is the establishment of other red blood cell indices.

The average volume of red blood cells correlate with the following indicators:

• SIT - indicates the average weight of hemoglobin in each red blood cell (norm metrics - from 27 to 31 pg) and a comparative analysis of the ratio is considered "the level of hemoglobin / numerical erythrocyte count";
• ICSU - shows the average level of hemoglobin in whole blood is not, but only in the red cell mass (the rate is from 320 to 360 g \ l).

Medical evidence shows that the violation of at least one of these red blood cell indices reflected in the other characteristics of the blood cell composition. All of the above indicators make it possible to determine the level of hemoglobin in a timely manner to prevent its decline and the development of blood diseases.

What to do when a deviation from the norm indicator

In the event that the common blood test results showed abnormal erythrocyte medium sized units upwards or reducing their size, do the following:

• together with your doctor to try to establish a causal factor in the change of red blood cells;
• streamline the regime of the day, a balanced diet, saturate it with products containing a sufficient amount of iron, iodine, vitamin B6, B12 (veal, meat nutria, rabbit, turkey, legumes, nuts, ocean fish, seaweed, shellfish, crustaceans);
• take drugs, to be appointed by the attending physician;
• completely abandon the use of alcohol, tobacco and drugs;
• Avoid a sedentary lifestyle, to engage in cycling, athletics and swimming.

MCV in the blood analysis - is an indicator, which tend to change under the influence of environmental factors. Therefore, to the average volume of the cells come to the optimum performance, an integrated approach using drug therapy, compliance with physician instructions and dietary standards power.

Registration of the article: Mila Friedan

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