Fibrinogen is the norm in the blood of women age. Table percentage increased, below normal. What does this mean, what to do

Fibrinogen - a protein that sformirovyvaetsya in the liver and is responsible for blood clotting. Its degree may vary, and this contributes to a number of factors. This is especially true of the female body, prone to hormonal surges. What should be the parameters, and as indicated by the deviation from the norm in women over the age shown in the table.

The role of fibrinogen protein in the body, the synthesis of

Fibrinogen - a colorless protein dissolved in the blood plasma, and participates in the constitution of the necessary blood clot formation after vessel injury, which is further processed into fiber. Whose filaments are entwined with each other and form a dense network. Which fall platelets and a strong base for the patch a temporary cessation of blood loss.

In addition to creating a protective clot the protein performs the following tasks:

• It helps to quickly restore the broken epidermis and damage to the inside.
• A positive effect on the vascular system when there is inflammation and protects against infection.
• It helps dissolve harmful blood clots.
• It contributes to the development of new capillaries.
• Participates in working blood cells from arteries.

fibrinogen norm for women of all ages

Norma fibrinogen in females:
up to 1 year	1.3-2 g / l.
2-6 years	1.7-3 g / l
6-14 years	1.7-3 g / l
15-25 years	2-4 g / l
After 35 years	1.8-4 g / l

rate of protein in female: 2-4 g / l (grams per liter), but in the critical days of performance are often inaccurate, this is due to natural changes in the body, when hormones are at a certain time and enhance the density of blood clotting to prevent large bleeding. Therefore, research is best done in 3-5 days after the menstrual period.

Reasons for the increase of fibrinogen above normal

Inflated protein indicators may occur in patients who use drugs with the content of steroid sex hormones. If its concentration is much higher than the permissible limits, it indicates inflammation or any problems in the body.

For example:

• Acute inflammatory and infectious diseases.
• Oncology.
• Complicated hypothyroidism.
• Necrosis.
• Rheumatoid arthritis.
• Autoimmune diseases.
• Peripheral artery disease.
• DIC (in the early stages of the disease).
• Amyloidosis.
• Pregnancy.
• Tuberculosis.
• Pneumonia.

Often this protein connection is temporarily above the allowed rate, it is affected by such factors:

• Critical days.
• Recent operations.
• Fresh burns and wounds.
• Cold.

During childbearing indicators rise to 6.5 g / l - this is the norm, because in this way, the body is rebuilt for a successful childbirth. If the protein concentration remains the same or goes down, it talks about serious violations.

At different stages of pregnancy are generally accepted such data:

• Up to 3 months - 2.5-5 g / l.
• 3-6 months - 2.5-5.1 g / l.
• 6-9 months - 3,7-6,1 g / l.

The reasons for lower rates of protein

Fibrinogen (at the rate of women by age, the table which is shown in the article, may vary slightly) from healthy women may increase or decrease, as the female body is very sensitive to hormonal rearrangements.

For example, during menopause because of the deceleration function of the reproductive system may experience a decrease in the protein, which is a natural phenomenon. Poor performance of the protein indicate the failure of plasma needed to produce blood clots during a fault.

This is a pretty serious violation, as too rare blood unable to clot in the required time, it can cause great harm to the body. A fibrinogen, which does not reach up to 1 g / L indicates a health problem.

The reasons for low rates:

• Liver failure.
• Diseases of the digestive system, which do not absorb vitamin K.
• Limfoblastoz benign.
• Toxemia, in which the body absorbs almost no food, because of this imbalance essential micronutrients.
• Leukemia.
• Beriberi (lack of vitamins C and B).
• Hereditary fibrinogenopenii.
• Erythremia.
• heart disease and blood vessels.
• DIC.
• Acute intoxication.
• Recently transferred to bleed heavily.
• Alcohol substance abuse.
• Vegetarianism.
• Prolonged and uncontrolled use of drugs, blood thinners, and as part of which contain aspirin.
• The use of anabolic agents and hormones.
• Polycythemia vera.
• The use of fish oil.

Symptoms danger fibrinogen deviation from the norm?

Inflated figures usually do not affect the well-being, for this reason, often the problem goes unnoticed. Which is quite dangerous, because it indicates a high protein concentration, which thickens the blood and complicate its movement through the veins.

Moreover this promotes the formation of harmful blood clots, which can move freely in the bloodstream.

This action severely in two cases: a large thrombus may occlude the artery, and then deforms it. Or vice versa, will easily move around, hitting one in the heart. Where will cause clogging of the valves, which would entail his arrest and imminent death.

Quite dangerous large concentration of protein during pregnancy, as much thick blood may be the culprit of such violations:

• Thrombosis and thrombophlebitis.
• Placental abruption and spontaneous abortions.
• Non-viable fetus.
• The birth of premature babies.
• Education gestosis.
• Thrombosis of the umbilical cord.

Low protein indicators (not reach 1 g / l) dangerous internal bleeding because any careless gesture is able to intensify the damage of large arteries that may povlekti serious problems with health.

When administered examination, blood tests especially on fibrinogen

To determine blood clotting appoint a special survey - coagulation, which is administered in the presence of such evidence:

• Before and after surgery.
• liver disease.
• Diseases of the cardiovascular system.
• Pregnancy.
• Undefined pathological changes in the body.
• Suspicion of hemophilia.
• The use of indirect anticoagulants (warfarin, acenocoumarol).
• Bleeding.
• DIC.
• Constant miscarriage, stillbirth.

Which could affect the test results?

Fibrinogen (at the rate of women by age, the table is presented in the article may vary from time to time) during pregnancy is increased to 6.5 g / l, as in this sensitive time there is a complete restructuring of the body, which is necessary for successful gestation child and childbirth.

It is forbidden to carry out a survey in the critical days, since the protein concentration is inaccurate, since this period of time is updated the blood. It is also undesirable event in the sultry season, because at this time the body is often picked up liquid. This also increases the plasma density, which could have a negative impact on results.

Because the quantity and quality of the collecting material may vary under the influence of various changes in the body, it is necessary to know in order to obtain accurate results, that contribute to a lowering of the protein and use of medications such substances:

• Androgens.
• Anabolic steroid.
• Anticoagulants.
• Antioxidants.
• Urokinase.
• Phenobarbital.
• Valproic acid.

Increase the protein concentration:

• Emotional and physical stress.
• Overweight.
• Increased sugar and blood cholesterol.
• The use of oral contraceptives.

Results of the study is not valid if the patient was sick during the manipulation of such illnesses:

• Syndrome nasal mucosa inflammation (rhinitis).
• Tonsillitis.
• ARI.
• Acute respiratory viral infection.
• Contagious disease of the respiratory tract caused by the influenza virus.

Preparation for analysis, blood donation

blood fibrinogen in women at different ages (under the table) differs from each other, for example if the figure reaches 2-4 mg after 15 years, it is considered the norm. A higher protein concentration may be indicative of the presence of infections and viruses, and reduced - of the problems in the liver, or vitamin deficiencies.

For the most accurate results of the survey need to follow these rules:

• The event should be done in the morning hour for 1-2 hours after sleep.
• The last meal should be for 9-12 hours prior to collection.
• Before analysis it is necessary to sleep well.
• It is forbidden to exercise the use of coffee and alcohol.
• It is desirable to refrain from the use of nicotine for 2-2.5 hours.
• Immediately before coagulogram need to drink 200-250 ml of purified or mineral water without gas.
• 15 minutes before the event is not desirable to be nervous and overwork, and physical activity to reduce to a minimum of 2-3 days prior to coagulation.

Survey accuracy also depends on the professionalism of the laboratory.
Patient taking medication affecting coagulation should notify the health care workers.

Decoding result

Fibrinogen (at the rate of women by age, the table is presented in the article is subject to change regardless of the physiological state) in healthy women often varies and is influenced by many factors.

For example, in the critical days of the protein unstable performance, Due to the natural course of the female body, when under the influence of hormones temporarily increases the density of the plasma and clotting systems to prevent major bleeding.

To decrypt the result, apply 2 columns with numbers: 1 patient are listed indicators in the 2 - the necessary standards. If the concentration of the protein corresponds to the set value, means of coagulation disorders were found.

Treatment of disorders of fibrinogen synthesis

It is important to know that the protein broken indicators should not be a reason for self-treatment. First you need to undergo a full examination and only then assigned therapy, the main task of which is to eliminate the culprit that causes this pathology.

Formulations for stabilizing protease level

To regulate the parameters can be assigned to these medications that affect the circulatory system:

• Antiplatelet agents - reduce blood clotting, thereby exert their prophylactic and therapeutic effect (Cardiomagnyl, Aspirin Cardio).
• anticoagulants - chemicals and drugs which suppress the activity of blood coagulation system and prevent the formation of thrombi.
• thrombolytics - aimed at the restoration of blood flow in the vessel due to a blood clot lysis within the vascular bed (Batroxobin, Biostrepta).
• Fibrinolitiki - cause the destruction of the formed strands of fibrin, they contribute mainly resorption of fresh (not yet exposed to the organization) blood clots (Tromboflyuks, Eberkinaza).

To normalize the protein mass is very helpful at increasing concentrations special meals, where there are such food:

• Onion.
• Beet.
• Tomatoes.
• Seafood.
• Cranberry.
• Raspberry.
• Green tea.
• Cocoa.
• Dark chocolate.
• Chicken and turkey.
• Veal.
• Legumes.
• Potatoes.
• Olive oil.
• Cabbage.
• Cherry.
• Bananas.
• Lemon.
• Buckwheat.
• Walnuts.
• Black currant.
• Eggs.
• Garlic.
• Dry red wine.

The use of such food helps to normalize and improve blood composition, besides they are perfectly relieve stress and have a positive effect on the entire body.

Emergency lowering fibrinogen concentration

Upon detection of a low protein therapy and reasons for such violations should be started without delay.

At the treatment of the disease intensify data violation recommended targeted pharmacotherapy for regulating parameters and prevent internal bleeding with the use of such medications:

• Aminocaproic acid.
• Transamcha.
• Etamzilat.
• Menadione sodium bisulfite.

Fibrinogen is a colorless protein mass, residing in the lymphatic system, which is formed in the liver and is updated for 4-6 days. It is called the plasma clotting factor 1 system. The norm of the protein in women over the age of different, as shown in a special table.

Author: Inessa Kalynovska

Useful video of fibrinogen and normal parameters

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