Indicator status passage metabolisticheskih processes of the human body called total protein in blood. Biochemistry and proteinogramma allow to evaluate the functioning of life support systems, to study for carbohydrate and lipid metabolism, timely detect and remove mineral and trace element deficiency, entering the cell tissue structure.
The content of the article:
- 1 What is the total protein in the blood and its significance
-
2 total protein standards Table in women by age
- 2.1 pregnant
- 2.2 when menopause
- 3 the overall rate of protein in men
- 4 Indications for study
- 5 Preparing for and conducting analysis
- 6 deciphering analysis
- 7 The reasons for the increased protein
- 8 The reasons for the reduced protein
- 9 Abnormalities during pregnancy
- 10 insecurity
- 11 How to normalize the protein level
- 12 Foods containing protein
- 13 Helpful videos about the total protein in the blood and its performance standards
What is the total protein in the blood and its significance
Total protein in the blood - is the total number of protein-protein binding (albumin-globulin part) blood supply, performing transport of fats and hormones to the cells of the body.
All protein found in the human body is made up of 3 factions with different composition of molecules and functional qualities:
- albumin - the largest group, comprising about 50-70% of all protein compounds. Directs maintaining blood osmotic pressure and composition, carries nutrients to the cells non-disintegrating in water.
- globulins - differ in the types depending on their destination: a-1 - are responsible for the generation and synthesis of hormones and fermentation of organic compounds; and 2 - the ratio is maintained in the blood copper ions, iron, calcium; beta - performing transporting functions, feeding the fabric arriving microcells; gamma-corrected state of the immune system, destroying viruses and bacteria entering the body from the outside.
- Fibrogeny - regulate the process of timely hemostasis in vascular damage.
The value obtained by proteinogram (or blood chemistry) - a set of all components with a consistency protein. protein level characterizes the functioning of the circulatory, hormonal systems, the digestive tract, for the chemical reactions of metabolism occurring in the human body.
The rate of protein metabolism depends on:
- liver conditions, kidney, pancreas and thyroid gland;
- lesion organism various toxins that cause the endogenous and exogenous intoxication;
- the amount of incoming power to the protein products;
- the state of blood clotting;
- presence of viral pathologies occurring in acute or chronic forms;
- Dysfunction of the endocrine and immune systems.
Appointment of protein fractions:
- Transport of nutrients, components of medicinal preparations to tissue cells;
- maintaining blood pressure occurring at the interface of a solution of salts or low molecular weight compounds (osmotic);
- regulating the composition of the blood, is necessary for normal human life;
- preservation plasma mineral substances and trace elements;
- participate in the process of secretion of hormones, enzymes, iron-containing protein (hemoglobin);
- activation of the protective properties of the organism;
- Backup storage of amino acids.
total protein standards Table in women by age
Total protein in the blood - is the amount of protein compounds of the female body, is directly dependent on the age, state of health, the numbers produced by the pituitary hormones. The total percentage of protein in the body (the norm) is from 17-20% of the total muscle mass.
Age | amount |
Girls younger than 1 year | 47-72,6 |
Up to 5 years of age | 61-73,9 |
From 6 to 12 years | 58-76 |
From 13 to 17 years | 57-75,7 |
After 18 years of | 65-86 |
Older than 61-year | 62,7-82,4 |
pregnant
Normal digital value LMC expectant mothers of - from 55 to 65 g / m.
The number of albumin-globulin fractions in the blood is lower, which is due to:
- increase of blood volume;
- lack of appetite, toxicity;
- increasing load on the body;
- fence kid large amount of amino acids and protein from the mother's body, necessary for the formation of the skeleton;
- changes in hormonal levels;
- the production of a particular protein, aimed at the preservation of pregnancy.
The lowest figures are seen in the 3rd trimester of pregnancy and just before birth, which is caused by increased growth of the fetus. Fall OCB values from a young mother saved the entire lactation period, as protein compounds are actively involved in the formation of breast milk
when menopause
With the emergence of menopausal estrogen production ceases and progesterone, which affects the rate of LMC. In women older than '61 in the body there is a decrease of albumin, globulin, while increasing index. The total amount of protein compounds remains in the normal range.
Fraction | Age period in years | ||
albumen | globulin | overall | |
59-62 | 38-42 | 97-104 | 22-34 |
52-58 | 32-45 | 98-103 | 34-59 |
53-55 | 43-45 | 77-103 | 60-74 |
49-55 | 46-52 | 95-107 | older than 75 |
the overall rate of protein in men
Total protein in the blood - is the flow rate of metabolism in men. LMC values vary according to age, muscle mass of the structure, the state of the cardiovascular, digestive, endocrine systems. The amount of blood protein fractions have a strong half of mankind greater percentage than that for women at 10%.
Age | Norm |
Up to 4 months. | 41-62 |
up to six months | 47-68 |
From 6 to 12 months. | 55-70 |
Up to 2 years | 57-76 |
From 2 to 14 years | 60-80 |
From 14-60 years | 64-84 |
After '61 | 62-81 |
Indications for study
The study of OCB carried out during blood biochemistry, the construction proteinogram.
Analysis assigned:
- women who are pregnant (normal figures should be reduced);
- professional athletes and people who are fond of increased physical activity;
- oncology patients;
- persons taking medications that alter blood protein content, promote blood clots (corticosteroids, androgens, thyroid hormones, progesterone and synthetic estrogen);
- the detection of iron deficiency anemia;
- in the presence of dehydration fact caused by poisoning, diarrhea, burns;
- with a strong loss of blood, provoked by injury, gastric, hemorrhoidal, menstrual bleeding pattern;
- the presence in a patient of acute or chronic renal and liver dysfunction;
- when systematic autoimmune pathologies accompanied by damage to the connective tissue;
- when detecting that entrainment of the low protein diet (diet).
Preparing for and conducting analysis
The total protein found in the blood - is the index of the state of the organism as a whole, is determined at the time of blood biochemistry and proteinogram. Analyzes provide an opportunity to detect deviations from normal performance, suggest the presence of concomitant diseases, correct previously started the healing process.
Preparatory stage:
- Two days before the analysis is necessary to give up drinking.
- For 24 hours before the procedure is required to remove from the diet of fatty, fried, saturated food proteins.
- During days before analysis (to the extent possible) do not apply any drugs. If cancellation is not possible tablet of the therapy you need to tell your doctor before starting decoding performance.
- Supper follows 8-9 hours prior to sampling biomaterial.
- After waking up, before the procedure is allowed to consume only clear water without gas content. Tea, coffee and milk are excluded.
- You should not smoke for 1-2 hours before blood withdrawal. The patient's condition should be calm and relaxed (prohibits any physical or emotional stress).
Procedure:
- A precipitate is taken from a vein.
- Before analyzing the patient must sit on a chair or couch, put his hand on the table and relax.
- The doctor puts a tourniquet 5-7 cm above the veins, asks the patient to open and close the hand for better blood flow.
- finger specialist feels venous artery cleans the surface of an alcohol requests clamp fist enters a special or butterfly needle. By the end of the device is connected to blood collection flask, harness untied.
- After taking the puncture biomaterial is washed with a disinfectant solution, imposed tight bandage.
deciphering analysis
rate of protein for adults - 65,6-84,9 g / l. In the figure is juvenile 56-75,5 g / l.
During proteinogram to establish the total amount of LMC biochemical tests conducted, showing the content of C-reactive protein (CRP), lowering which informs about the development in the patient's body:
- rheumatic diseases of the joints and muscles;
- chronic lesions of connective tissue and blood vessels, followed by the generation of autoimmune antibodies;
- myocardial infarction;
- inflammation, provoking the destruction of the heart and blood vessels.
The increase in rates is a sign of the SBC:
- acute or chronic viral pathologies;
- smoldering allergic processes;
- acute infections (meningitis, tuberculosis, sepsis figures DRR exceed 100 m / l);
- tissue damage different etymology (burns, cuts, previous surgery);
- endocrine disorders (diabetes, obesity, hormonal metabolism disorders);
- cancers;
- lipid metabolism.
Increasing rheumatoid factor indicates the development of rheumatoid arthritis.
Symptoms with small deviations in the amount of blood protein compounds are missing. In case of increase of the value of the norm by more than 50 units. swelling may occur extremities and soft tissue.
Decoding performance components protein parts OCB analysis:
Age | albumin | Alpha-1 globulin | Alpha2 Globulin | Beta-globulin | Gamma globulin |
1 week of life | 31,5-40,8 | 1,3-4,6 | 7,6-11,4 | 4,7-6,9 | 3,3-8,7 |
Before the first year | 33,8-41,7 | 1,5-4,9 | 7,6-11,4 | 4,8-7,6 | 3,3-8,7 |
Up to 5 years | 33,7-44 | 2,3-4,6 | 7,3-12,9 | 4,7-8,6 | 5,3-10,6 |
From 6 to 8 years | 38-47,1 | 2,4-4,8 | 9-11,5 | 5,3-8,7 | 5,3-12 |
8-11 years | 41-45 | 2,2-4 | 7,5-10,2 | 5,6-7 | 5,4-12,6 |
11 years-'21 | 39-49 | 3,3-5,4 | 7,2-10,3 | 5-9 | 7-13 |
Over 21 years | 40-47,5 | 2,1-3,6 | 5-8,3 | 6-9 | 8-13 |
If the SBC and the Russian Federation is in the normal range, laboratory aims to "negative."
The reasons for the increased protein
Total protein in the blood - a combination of protein fractions, which increase It is observed only in the development of dangerous pathological dysfunctions of the body:
- oncological processes involving collapse of protein compounds;
- DNA predisposition to hyperproteinemia;
- leprosy;
- strong dehydration accompanying the condensation of the blood caused by poisoning, diarrhea, vomiting, burns;
- massive destruction of soft tissue due to ischemia, toxicosis;
- tropical infections;
- diseases of infectious nature, occurring in acute or chronic phases;
- autoimmune pathologies (hepatitis, rheumatoid arthritis);
- diabetes insipidus;
- cirrhosis;
- cholera.
Temporary Hyperproteinemia cause infectious disease, a large loss of fluid in the body, intestinal obstruction, hindering the absorption of water, heavy bleeding.
The reasons for the reduced protein
Common indicators of blood protein may be reduced in case of:
- pregnancy, breast-feeding;
- fad increased physical exercise;
- increased physical activity prior to blood sampling for biochemistry;
- hobbies low-protein diet.
Reduction in the presence of OCB numbers above reasons considered relative eliminated spontaneously after the disappearance of provoking factor.
Lowering the amount of blood protein is shown:
- decreased libido;
- low working capacity;
- chronic fatigue syndrome;
- apathy;
- low resistance to infectious diseases.
By pathological processes that lead to a decrease in laboratory numbers indicating the number of blood total protein, include:
- diseases of the liver, pancreas, adrenal gland;
- malignant neoplasms;
- Iron-deficiency anemia;
- the extensive burn surface;
- hyperthyroidism;
- poison entering the body when consumed fungi, berries, a large amount of drugs;
- enterocolitis;
- Process malabsorption disorders (food intake in bowel);
- diabetes;
- infectious disease;
- severe bleeding different etymology;
- preeclampsia pregnant.
Relative hypoproteinemia (reduced amount of blood protein) there is:
- after the surgery;
- chronic administration of corticosteroids, hormonal preparations;
- subject to a vegetarian diet (low protein diet obsession).
- after a blood transfusion.
In children, low protein indicator points to:
- muscle deficiency;
- delay mental and physical development;
- decreased immunity.
Abnormalities during pregnancy
During pregnancy, the total number of proteinosoderzhaschih links in the body of the future mother is reduced to 25-30% of normal.
Decrease is due to:
- increase in body weight and blood circulation.
- poor appetite provoked by hormonal fluctuations, toxicity, depression.
- the consumption of the fruit of the parent protein and amino acids to build their own skeleton;
- the participation of the albumin-globulin fractions in the formation of protein pregnancy produced to maintain the normal development of the baby.
- Protein is spent on maintaining the hard work of the endocrine glands responsible for maintaining pregnancy.
- increasing the plasma volume, which leads to fluid retention in the blood vessels.
During a 9-month period, she rents analysis to determine biochemical parameters of at least 3 times.
The discrepancy with the standard values suggesting abnormal development of the embryo. LMC rate for pregnant 63-83 g / l. Doctors not apply drugs at lower rates and 50 g / l. In case a reduction of pathological protein young mother sent to the hospital for further diagnosis and correction condition.
Greatly reduced the number of protein fractions in the blood is dangerous for pregnant women because it can provoke:
- The lack of weight gain, which suggests a stop in the development of the baby. The signal for the occurrence of a dangerous disease may be a high level of hemoglobin (normal pregnant reduced iron content) particularly at the 2- 3rd semester.
- Edema, dropsy pregnant.
- Intrauterine growth restriction.
- Increased hepatic enzymatic properties.
- High blood pressure in the future mother, arising from blood clots.
- Preeclampsia - complication of normal current of pregnancy, manifesting deterioration of the young mother and the unborn baby.
For the normalization of biochemical indicators of a woman expecting a child must be:
- eat right, avoid fatty foods, opting for vegetable products;
- drink per day for at least 1 liter of water;
- include food vegetables, cheese, fruit, nuts, herbs;
- in the case of edema, increased blood pressure, dizziness, immediately report symptoms of a gynecologist.
insecurity
Proteinosoderzhaschih oscillation of particles in the blood is not harmful to the body and is not dangerous. In the case of increasing the protein concentration of blood occurs, resulting in reduced circulation slows oxygen supply and minerals cells.
there are:
- severe fatigue;
- reduced concentration and memory;
- offline functionality;
- there is muscle weakness.
By reducing the OCB performance cellular starvation occurs causing:
- dizziness;
- headache;
- apathy;
- fainting;
- chronic fatigue.
These conditions are dangerous for people employed in jobs requiring a high concentration (in the management of transport and work with mechanisms), the use of great physical strength. Danger is not variation in the amount of proteins, and the causes of this deviation from normal values.
Changes in analyzes provoke:
- oncologic pathology;
- severe bleeding;
- kidney and liver;
- entering the body potent poisons;
- trauma;
- burn injury;
- dysfunction of the endocrine system, provoking a violation of metabolism.
How to normalize the protein level
In identifying deviations from the normal protein level values necessary to carry out urgent diagnostics, identifying the causes of pathologies and destination timely treatment. Normalization protein level is carried out only under the supervision of a physician.
Self to self should not be. The first step is to find out the disease, which caused a jump OCB indicators and begin treatment immediately.
In addition, you must:
- adhere to proper nutrition, to give up fatty, fried foods, carbonated beverages, large amounts of sugar;
- correct nutrition, depending on the pathology;
- with a high protein level should eat large amounts of raw vegetables, fruits, vegetables;
- observe the regime of the day, be sure to get enough sleep;
- not abuse physical, athletic exercises.
- try less nervous, avoid stress;
- as far as possible to give up (lower dosage) of medicines that caused the jump indicator protein;
- eliminate smoking, abuse of alcohol-containing beverages;
- cure all the gastrointestinal tract infections.
- regularly (at least 1 times per year) take preventive medical examination.
Drugs that increase the protein component of blood, does not exist.
For the treatment of giperproteninemii appointed:
- medications that normalize the levels of dextrose in the blood;
- tablets, lowering blood pressure;
- immunomodulators.
To increase the content of protein compounds in the body help foods rich in protein. Daily protein intake for men is 100 g, for women - 70 g Athletes, persons employed in jobs that require the use of a lot of physical strength, pregnant women and nursing mothers need to increase the daily consumption rate of protein compounds by 2 times.
Foods containing protein
Body needs protein structure of animal and vegetable origin.
A large number of animal protein is contained in:
- lean meat and fish (cod, hake, rabbit, turkey, veal);
- seafood (squid, crab, clams);
- offal (liver, kidney);
- egg powder;
- hard cheese;
- low fat curd mass.
Vegetable protein is in:
- soybeans;
- peanuts;
- almonds;
- hazelnuts;
- dried apricots;
- unpolished rice;
- oatmeal;
- lentils;
- baked goods, rich bran;
- pasta made from durum wheat.
The daily nutritional diet, in addition to protein foods, need to include foods that helps increase blood component OCB:
- mushrooms;
- berries;
- roots;
- fruits.
Dietary recommendations:
- Food should be varied. Eat constantly the same products should not be.
- It is necessary to restrict the products, having a plurality of fat in the composition and the average number of proteins: pork, lamb, beef; cheese, fat content exceeding 20%; eggs.
- Should not be immediately incorporated into the daily diet of a large number of protein products. The change in diet should be gradual. Unusual foods provoke severe indigestion.
Table of products that contribute to a decrease in protein content in the blood:
Vegetables | Legumes and cereals | Fish | Fruits | berries | Greenery |
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Folk remedies to help reduce the OCB:
- decoction of birch buds and fir;
- juice from cranberries, cherries, cranberries;
- infusion of pumpkin seeds;
- honey, propolis.
The content of total protein in the blood - a measure that indicates the coordinated work of all internal body systems. Not being a distinct disease, abnormalities - a significant basis for a full examination of the body with the aim of identifying and removing serious pathological processes.
Helpful videos about the total protein in the blood and its performance standards
The necessary tests during pregnancy:
For more information about a blood test for the protein: