One type of white blood cell white blood cells - eosinophils, which are the norm in minor respects in children and in adults. Taurus are granulocyte group and performing a specific protective role.
What do the eosinophils
Eosinophils in the body responsible for the destruction of the extracellular foreign agents hostile to the human body, resulting in the following effects:
- antiparasitic increase immunity by enhancing the sensitivity of specific receptors, and thereby the probability of destruction of the membrane of cells of parasitic organisms;
- activation and the release of biologically active substances with which suppresses inflammatory processes;
- aid in the absorption and binding of inflammatory mediators, most of histamine;
- destruction of small foreign particles, their absorption method.
These cells have the ability to penetrate and deposit in blood vessels in the inflammation.
normal levels
Norm of eosinophils varies slightly in children and adults, men and pregnant women.
Category | Norm (ratio in%) |
Children from 0 to 5 years | 1-6 |
Children from 6 to 10 years | 1-5,5 |
Children from 10 to 21 years | 0,5 -5 |
Women | 0,5-5 |
Pregnant women | 0-0,5 |
men | 0,5-5 |
Thus, in the table we can see that the number of eosinophils varies up to the age of 21, and then it is the same in both sexes, excluding the state of pregnancy in women. During his life in the blood of healthy adult human percentage of eosinophilic granulocytes stable.
Among women
Norm of eosinophils in the blood of women is reduced in the period of childbearing, but returns to normal within 2-4 weeks after birth.
After 50 years of blood eosinophils normal in women over the age can be in the range of 1 to 5.5%, but in general their number is not changed due to age.
men
The normal value of eosinophils in the blood of a man (adult) does not exceed 5%, but may be reduced in connection with chronic fatigue syndrome, or in patients with Down syndrome.
The causes of variances
You should know that eosinophils figure may vary depending on the time of day, as is associated with the adrenal glands. In the morning and in the evening it will be lower than the daily average, and at night - up. Therefore, when interpreting the results must take into account the percentage of variation in different times of day.
If the content described eosinophilic cells increases in the blood, there is a condition called eosinophilia. There are three degrees of pathology:
- slight (not more than 10%);
- moderate (15%);
- expressed (over 15%).
It may indicate the presence of a number of disorders in the body:
- allergies;
- parasitic diseases;
- non-atopic skin diseases;
- diseases of the gastrointestinal tract;
- rheumatism;
- blood diseases;
- violations in the broncho-pulmonary system;
- weak immunity;
- response received by the subject patient drugs.
By increasing the index primarily arise suspected allergy or parasitic infection as the most common cause of eosinophilia.
When the targets were exceeded in childhood, conditions may be slightly different:
- up to 6 months - Rhesus conflict aureus, colitis, eosinophilic origin, serum sickness;
- from 6 months to 3 years - atopic dermatitis, allergies to medicines, angioedema;
- from 3 to 12 years - scarlet fever, chicken pox, allergic rhinitis and skin allergy.
When the number of eosinophils decreased, a condition called Eosinopenia. The indicator then may drop to 0. When the cells are reduced to a critical value, this may indicate the presence of appendicitis in the body, leukemia, diphtheria or typhoid fever, which is dangerous for the patient's life.
After the injury, surgery, sepsis or previous non-severe infections, myocardial infarction, vascular problems network mercury intoxication, diseases of the thyroid or adrenal possibly a small decrease in the level eosinophils.
Low blood levels of eosinophil cells occurs in people with Down's syndrome or chronic fatigue condition.