Eutiroks. Reviews, side effects, overdose. Instructions how to take diet pills, pregnancy, hypothyroidism

Eutiroks - hormonal agent, appointed in violation of the functioning of the thyroid gland. The dosage varies depending on the effect of the drug on the body, and also increases the number and severity of side effects. According to the feedback, when receiving funds according to the instructions, the drug's effectiveness is high.

the drug

The main element is sodium levothyroxine Eutiroksa - artificial analogue hormone produced by the thyroid gland. For the convenience of the reception preparation is produced with a content of the first dose of 25-150 mg of the active element.

To impart the required shape, extending the shelf life and improve the digestibility of the agent include additional elements:

1. Corn starch. It is necessary for thickening agents. Additionally helps to strengthen the muscles, restore nerve cells and removes waste products and toxins from the body. The unit dose contains 25 mg.
2. Gelatin. It is also used as a thickener. In addition, it restores the joints, strengthens bones and promotes weight loss. Contains 5 mg.
3. Lactose monohydrate. It gives drug sweetness. Additionally replenishes energy reserves and normalizes calcium metabolism in the body. Contained 65.98 mg.
4. Croscarmellose sodium. Accelerates the absorption of the drug. It contained 3.5 mg.
5. Magnesium stearate. Used for a firm connection of all components means. Contained 0.5 mg.

The number of additional components does not change with increasing concentration of active component in a unit dose.

Pharmacological properties, the shape of the drug release

Eutiroks produced in standard tablet form (single-sided crosspoint risk, on the other sign "EM" with an indication of the amount of active substance). The main property of the drug - a lack of replenishment of hormones produced by the thyroid gland. Tablets are packaged in blisters of 25 pieces.

The carton contains 2 or 4 plates. For the convenience of choice, depending on the course of treatment.

Pharmacodynamics and Pharmacokinetics

Eutiroks, reviews (side effects develop when non-compliance with the instructions for use) acts depending on the dosage consumed. The main purpose of the active substance - to normalize the real exchange, and to regulate the process of tissue growth and development.

Changing the effect of the drug at different dosages:

1. In smaller doses to accelerate the synthesis of proteins and fats.
2. With an average dosage of accelerating the process of formation and development of new tissue cells, thereby increasing the body's need for oxygen. Metabolism of proteins, fats and carbohydrates is also accelerating. Nervous and cardiovascular system work in active mode.
3. At high doses there is oppression of the important parts of the brain (hypothalamus and pituitary).

Independently excess doses can lead to a decrease in brain efficiency and deterioration in the operation and development of all organs. For small deviations functioning thyroid therapy efficacy is noted after 10 days. In the pathology - diffuse goiter, an improvement from the treatment occurs within 4 months.

After ingestion of the main drug absorption occurs in the small intestine. The use of food decreases the rate of drug action. The maximum number of components in the blood is detected Eutiroksa through 5 hours.

The main elements of metabolism occurs in the liver, muscle and brain. Derived metabolites in the bile, through the rectum and the urine through the kidneys. The output time can vary from 3 days to 10 days, dependent on the state of the thyroid gland.

Indications for admission

Eutiroks pills should be taken strictly on the evidence and on the appointment of specialists.

Indications for admission are:

• lack of hormones produced by the thyroid gland. It may develop due to a pathological condition of the body or as a result of hormone in the body fails. Also a deficiency can occur as a result of taking medication. Tablets fill hormone deficiency;
• enlarged thyroid (goiter euthyroid). The disease develops due to lack of hormones. organ function is not impaired. It marked increase in visual goiter. Tablets compensate deficiency and lead thyroid the normal state;
• an overabundance of thyroid hormones (diffuse toxic goiter). Developed as a result of autoimmune pathologies. As a result, the disease is hormone poisoning organism. Tablets are assigned to normalize hormone;
• after partial or complete removal of the thyroid gland. Tablets are necessary to normalize hormonal;
• after surgery on the prostate, without removing it. Tablets accelerate recovery operation body;
• as a diagnostic tool to detect thyroid gland malfunctions.

Depending on the pathology endocrinologist selects the dosage and duration of therapy. Self-adjustment of treatment is unacceptable.

Contraindications

Eutiroks (reviews of adverse effects suggest that complications develop while ignoring the patient contraindications) can not be used without the prescription of a specialist. Before initiation of therapy must be excluded existing prohibitions.

And relative contraindications to direct Eutiroksa:

direct contraindications	Contingencies (reception allowed after examination by the right people)
Intolerant elements medication.	If it affects the coronary arteries.
Incurable functioning adrenocortical insufficiency.	Violation vascular condition. Existing heart attacks in history.
Persistent increase in thyroid hormones.	Regular pressure.
Malfunction of the hypothalamus or pituitary gland.	Violation of the rhythm of heartbeats.
Recent myocardial infarction.	Elevated glucose levels in the body.
Abnormal cardiac function.	Sustained reduction in thyroid hormones without response to medical therapy.
Simultaneous treatment with analogues of the drug containing iodine.	Malabsorption of substances in the rectum.
In case of violation of the patient's psyche.

When conventional contraindications, an endocrinologist may prescribe drug treatment, but with individual selection of dosage and constant control of the patient's condition. For direct contraindications selected analogue Eutiroksa.

Instructions on the use of funds. General provisions

Eutiroks (dosage) is assigned depending on the pathology and existing contingent of contraindications. Each patient therapy is chosen individually. According to reviews, side effects occur only in case of violation of therapy designated endocrinologist. Whatever (weight loss or normalization of the functioning of the thyroid gland) there are general rules of taking the pills.

Appointed single dose taken in the morning on an empty stomach. Can not chew the tablet, generally use form, with water of at least 120 ml. If it is impossible swallowing whole tablets it is necessary to dissolve to obtain a homogeneous suspension. Required track body's response to the drug.

If a pill is accidentally omitted, it is necessary to use immediately upon detection. Sometimes you may need to consult an endocrinologist (especially if therapy is appointed in severe pathologies). The standard dose of the drug for women is 75 mcg, 100 mcg men.

In treatment of a single dose - 50 mg. This takes into account compatibility of the medication. Eutiroks should not be taken later than 4 hours before bedtime. The drug affects the nervous system and can worsen the process of falling asleep, and sleep quality.

The dosage and regimen of medication slimming

Overweight often develops due to metabolic disorders. That is often associated with impaired functioning of the thyroid gland or the aging of the organism. Receiving Eutiroksa to accelerate the exchange process (proteins, fats and carbohydrates), thereby reducing body weight. This reaction develops at an average dosage of the drug.

Additionally, the tablets have the following effects:

• decreased appetite;
• "Desire to increase physical activity" by acting on certain areas of the nervous system;
• promote rapid burning of calories;
• do not allow to form new body fat.

Weight loss can occur without the use of exercise and dieting. Body weight change over is considered to be a side effect of the drug, so experts do not recommend taking pills to reduce body weight.

Hormone action is accompanied by side effects, particularly in self-selection of dosage. Eutiroks can cause malfunction of organs (particular danger is the failure of brain, cardiovascular, and nervous systems).

To exclude the development of side effects of pills is recommended to take at the following dosage:

1. Within 7 days used 25 micrograms in the morning and evening (please note that the last reception shall be not later than 7 pm).
2. From 8-th to 21 th single day dosage is increased by 2 times (50 mcg) three times and used within one day.
3. From 22 th to 31st daily use of 75 mg 3-4 times a day.

You can not use a daily dose of one-off, it will trigger the development of serious side effects (malfunction of the heart, nervous system).

Next there is a break of at least 1 month. In normal thyroid condition, receiving active drug may initially provoke an increase in body weight. After completion of the course, you must follow a diet, or weight quickly comes back.

Eutiroksa doses for medicinal purposes

The therapeutic course of medication depends on the age, type and severity of the pathology of the disease. Therefore, most treatment is chosen individually.

Treatment of diseases in adults (55 years):

1. With a lack of thyroid hormone. The daily dose is 1.6-1.8 g per 1 kg body weight. When neglect pathology treatment begins with 12.5 micrograms per day. Every 2 weeks the dose is increased by 12.5 g. The course of treatment is carried out at intervals of 60 days. Duration of therapy is regulated by laboratory parameters hormone concentrations in the blood. Therapy may be appointed until the end of life.
2. When enlarged goiter appointed by the single dose of 75 micrograms for women and 100 micrograms for men. With the gradual increase up to 200 micrograms per day.
3. When elevated levels of thyroid hormones. To normalize the functioning of the assigned organ receiving 50 mcg, gradually increasing to 100 micrograms.
4. After complete or partial removal of the prostate. Starting dose was 50 ug with weekly increasing to 300 micrograms a day.
5. After surgery on the thyroid glandAnd as prophylaxis, it is necessary to take a one-time 75 mg, increasing to 200 micrograms.
6. To test the functioning of the glandTablets are appointed within 30 days prior to the procedure. From 1 to day 14 received 75 mg per day. From 22 th to the 30 day of 150-200 g per day.

The course and the amount of increase means an endocrinologist is selected each week.

Treatment of thyroid abnormalities in adults over 55 years:

1. With a lack of hormones. Initial single dose is 0.8-0.9 g per 1 kg body weight. Increase dosage prescribed individually.
2. When enlarged goiter initial dose of 25 ug with a gradual increase.
3. When elevated levels of hormones single dose in the first week is 25 mcg increasing to 50 micrograms.
4. After removal of the prostate assigned to take tablets with 25 mg increasing to 200 micrograms.
5. In the postoperative period is assigned to 50 mcg to 150 mcg per day.
6. In conducting the test. Dosage is appointed by the patient's condition and age. After 70 years, the procedure is rarely done.

Therapy for elderly requires more careful control, as the organism can cause deterioration of unpredictable side reactions.

Treatment of thyroid disease in childhood:

name of disease	0-6 months	6-12 months	1-5 years	6-12 years	Older than 12 years
The lack of hormones produced by the thyroid gland	25-50 mcg	50-75 mcg	75-100 mcg	100-150 mcg	100-200 mcg
Increased crop (the drug is taken with a gradual increase of the endocrinologist destination)	25	25	50	50	75
The overabundance of thyroid hormones. It requires a gradual increase in dosage.	12,5-25	12,5-25	25-50	25-50	50-100
In case of partial or complete removal of the organ. Increase dosage appointed expert.	12,5	12,5	25	25	50
After operation on iron and in the prevention of	Therapy is prescribed individually depending on the patient's general status
For the test	Held on the testimony and the control of the pediatrician and endocrinologist. The dosage is prescribed individually.

Children under 5 years old tablet is dissolved in water to a slurry. And allow to drink 30-40 minutes before feeding. In infancy it is necessary to monitor the child's reaction to the first dose of the drug and its increase.

Pregnancy and hepatitis B

Eutiroks, reviews, (side effects in the form of violations of the formation and development of the fetus, have been identified) can be taken during pregnancy and lactation. If a woman was treated with Eutiroksa before conceiving a baby, it is necessary to continue reception.

Endocrinologist should, with the help of calculations, increase the daily dose. Otherwise, a failure in the functioning of the thyroid gland could have a negative impact on a child's development.

In primary assignment specialist must take into account the compatibility of vitamins consumed by pregnant or nursing women. And also eliminate existing contraindications. Independently increase the dose and the course is dangerous to life of the mother and child. Since breast milk is transferred to a child a small part of the drug that has no effect on its development.

Side effects

Long-term use of the drug may be accompanied by the manifestation of side effects:

• allergic rashes on the skin with accompanying pruritus, conjunctivitis and also swelling of tissues;
• Hair loss due to allergies or hormonal changes;
• increase or decrease in appetite and weight;
• rarely nausea;
• sleep disorder later use of the drug;
• Changes in temperature indicators of the body;
• a small tremor of the extremities;
• violation of the periodicity of the menstrual cycle;
• increased sweating, even at rest.

In identifying the side effects of the drug is canceled up to determine the cause. Perhaps the decline in unit dosage or replacing analog. Adverse reaction stops on its own after the abolition of tablets.

Overdose

The first symptom of overdose is drastic weight loss without any reasons.

In addition, notes the following changes:

• disruption of the heart, accompanied by pain and malfunction rate;
• regular headaches that hard drugs are eliminated;
• strong tremors in the limbs;
• increased weakness due to rapid metabolism;
• enhanced blood flow to the face (because of this, the skin becomes red, and feel the heat);
• possibly fever;
• vomiting, and diarrhea, as overdose followed by intoxication of the organism;
• violation psychological balance (psychoses, nervousness, irritability);
• strong violation of the periodicity of menstruation;
• malfunction of the liver and kidneys;
• in children can impair the function of brain cells.

With strong overdosing can cause cardiac arrest. After discontinuation of the drug on their own condition is stable. In severe patient's condition necessary gastric lavage and intravenous administration of beta blockers (blocked to the drug sensitivity of receptors).

Interaction

Eutiroks (for reviews, side effects often develop non-compliance with drug interactions with other drugs) It can affect the absorption and the therapeutic effect of other drugs:

1. It enhances the effect of drugs designated to reduce blood clotting. It is necessary to change the dosage of anticoagulants.
2. It increases the effect of anti-depressants. At impossibility of their cancellation are replaced Eutiroksa.
3. Not combined with insulin products, as it reduces their effectiveness.
4. Reduces effects of medicines appointed to normalize the functioning of the heart.
5. Medicines to lower cholesterol in the blood affects the absorption in the intestine Eutiroksa.
6. Estrogensoderzhaschie Eutiroksa drugs reduce efficiency. You need to change a single dose or withdrawal of drugs is required.
7. Anabolic steroids reduce Eutiroksa action to a minimum. Necessary to replace one of the drugs.
8. Eutiroksa adjustment of dosage is required while receiving drugs against HIV infection.
9. When simultaneous administration of antiepileptic drugs and Eutiroksa decreases the effectiveness of both agents.
10. Diuretics can reduce the effect of Eutiroksa.
11. Aluminum and iron medications must be taken no earlier than 2 hours after administration Eutiroksa, as they may interact with each other and reduces the effectiveness of both agents.
12. In applying iodine preparations Eutiroksa need to change dosage.
13. Medication is not combined with the consumption of soy products, they reduce its effectiveness, it is necessary to increase the dose of the drug.

Do not always need to replace the drug in some cases it is sufficient to withstand the time interval between doses of medication. Compatibility of drugs, their dosage and the need to replace refined specialist.

Shelf life

Tablets can be used for 3 years from the date of manufacture when stored in a dark place at a temperature not higher than 25 degrees.

Terms of sale

Eutiroks can be bought in the presence of a recipe with instructions for use and an indication of a single dosage.

analogs

In hypersensitive or to replace the components of the drug, because of the duration of application, can be replaced Eutiroks analogue.

A list of recommended drugs:

• tibon.
• levothyroxine sodium.
• tireotom.
• Thyreocombum.
• tireoidin.
• L-thyroxine.
• bagotiroks.
• novotiral.

When replacing Eutiroksa necessary to consider a new drug contraindications, age restrictions and therapy.

Eutiroksa cost in pharmacies of Moscow, St. Petersburg, regions

The cost of the tablets varies from region to region, the concentration of active substance with a first dose and the number of tablets in the package. The table contains the price range for Eutiroksa with an active element in an amount of 50 g of 50 and 100 tablets per pack.

City	Cost in rubles for 50 tablets	Cost in rubles for 100 pills
minimal	maximum	minimal	maximum
Moscow	110	150	140	170
St. Petersburg	115	152	135	170
Yekaterinburg	120	155	140	175
Permian	115	150	135	165
Sochi	105	135	115	140
Vladivostok	97	130	100	125
Tyumen	110	145	120	160

Eutiroks is an effective drug, in the opinion of patients. Subject to receiving the instructions and recommendations of the doctor side effects have been observed in rare cases, allergic reactions such as rash.

Author: Svetlana Kotlyachkova

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