Aminocaproic acid. Instructions for use in children's nose, the solution inside the inhalation nebulizer. Composition, indications for use for children, during pregnancy, during SARS, adenoids, rhinitis

Medical appointment aminocaproic acid - styptic.

The instructions for use indicate that the role of the participant hemostasis it reduces the permeability of small blood vessels, eliminating these hemorrhagic bleeding; inhibit (delay) dissolving clots sealing disturbed blood artery; toksikofiltruyuschuyu increases the ability of the liver; suppresses allergic reaction.

The acid is rapidly absorbed in the tissue, the peak concentration in the bloodstream occurs within 2-3 hours, it is output via the kidneys in unchanged form in the volume of 40-60%.

Structure

Aminocaproic acid (ACC) in the pharmacological complemented prefix naming ε (epsilon), obtained as a result of hydrolysis polymerization ε-caprolactam - polyamide derivative nylon. ACC in its final form - a man-made protein that is compatible with human cells.

A 5% injection liquid ACC diluted with isotonic saline (sodium chloride, water). The powder form of the drug is present only aminocaproic acid. The tablets are added auxiliary ingredients: povidone (enterosorbent), crospovidone (amplifier solubility of the components), stearic acid (thickener), a salt thereof - as magnesium stearate stabilizer.

production form

Aminocaproic acid, instructions for use which is given later in this article, is sold in different forms and volumes:

• solution for intravenous, drip (clear, colorless) with 100 ml, 200 ml glass bottles; 100, 250 ml, half-liter, liter in hard and soft polymeric containers;
• white crystalline powder, odorless, colorless crystals or oral intake of 1 g in individual single or twin bags;
• tablets White round 500, ACC 1000 mg in a blister pack of tablets 12 to 1-2 in a carton box, in plastic jars of 50 tablets.

Such forms of selected manufacturers to meet the needs of medical institutions. Liquid preparations for intravenous injections required for acute bleeding during surgery, as well as instillation, nasal wash, gum treatment.

Tablet, powder receiving means for enteral (swallowing) claimed at the internal and external bleeding, when rotavirus disease, inhalation treatment adenoides, cough, rhinitis long, sinusitis.

testimony

Infuzivnoe and oral use of drugs aminocaproic justified in the following cases:

• surgery that causes increased activity of fibrin (brain, lung, thyroid glands, pancreas, prostate, as well as in the abdominal, urology, gynecology departments, in the oral cavity - tonsillectomy, dental manipulation);
• heavy uterine flow of blood, including the miscarriage, abortion complications, placental abruption, menorrhagia;
• vitro (artificial) circulation;
• rehabilitation after operating actions in vascular, cardiac systems;
• treatment of severe burns;
• hemorrhagic syndrome (intense internal blood effusion in the gastrointestinal region, the bladder;
• hyperfibrinolysis different nature, including the thrombolytic agents, transfusion of large amounts of conserved blood;
• bleeding due to thrombocytopenia (low clotting);
• anemia syndrome type of Diamond Black fan - inhibition of growth, maturation of blood cells, platelets;
• cirrhosis;
• blood in the urine (haematuria);
• some forms of cancer;
• spontaneous nosebleeds, and associated upper respiratory operations;
• large amount of mucous secretion, edema of the nasal mucosa overlying the passage of air;
• rhinitis, sinusitis various etiologies with severe inflammation;
• adenoiditis - inflammation of the pharyngeal tonsils;
• the need for prevention of SARS, influenza, rhinitis complications.

Contraindications

Not appointed ACC preparations at:

• organism hypersensitivity to a substance;
• thrombosis, thromboembolism;
• disorders, kidney diseases and related difficulties excretory functions;
• coagulopathy - distortion pathological clotting reaction;
• ICE syndrome - circulated through the vessels formation of clots that violates the circulation;
• pregnancy, breastfeeding;
• disorders of cerebral blood flow;
• idiopathic flow of blood (no particular reason).

Under the strict supervision of a physician aminocaproic used drugs, if there are valvular heart disease, hypotension, chronic renal failure, liver. Infants treated with extreme caution in view of features unformed body.

It is considered inappropriate to use the medication to prevent a large loss of blood during childbirth. When the reverse migration of hormone excreted in the postpartum period may have serious thromboembolic risks.

Side effects

Often the drug interacts well with human tissues and biological fluids.

However, long-term statistics accumulated data found negative precedents:

• noise in ears;

  

• floating sensation, pain in the head;
• nausea, vomiting, upset his chair;
• rashes on the skin;
• difficulty in nasal breathing;
• hypotension, including orthostatic (blood reflux from the head with a sharp rise, extension housing, long standing);
• convulsions;
• muscle weakness;
• slowing or irregular heartbeat;
• subendocardial bleeding in the inner layer of the heart attack;
• acute renal dysfunction;
• hemodilution.

Single or a combination of side effects often go away after tapering.

Instructions for use at a cold

ACC drops administered in the complex treatment of upper respiratory disease, alternating with antiviral, interferonsoderzhaschimi means. With their help relieve swelling of the mucosa, reduce inflammation, selection exudate.

Drops reduce symptoms of allergic rhinitis, pruritus by influencing the production of histamine - mediator causing inflammation as a protective response. Acid is not a vasoconstrictor, so can not quickly "break through" the breath.

As drops suitable infusion solution 5% - Ready or ordered at the pharmacy 10 ml. To treat the nose, babies laid on his back, his head turned to one side and slightly upward.

After instillation of one side of the nose have to wait for 2-3 min., Then also repeat on the other side. Older children spend sitting manipulation. If wicking of the drug into the eye was washed with running water.

Aminocaproic acid (solution) is allowed in the following dosages:

1. 1-5 years - with a cold 1 drop in each nostril 3 times. The course lasts no more than 5-7 days.
2. 5-12 years - at a cold 2-3 drops into each nostril four times by the same rate.
3. Teenagers, adults - 3-4 drops in both sides of the nose with the common cold. In the case of acute rhinitis, sinusitis with the same amount of wet turundy, inserted into the nose for 10 min. 5 times a day (every 3 hours).
4. For prevention in poor epidobstanovke influenza, SARS - 1-4 drops 4 times during the week.

To use the nasal spray treatment with ACC. Useful as an ointment with mashed into powder aminocaproic powder. It is added in the amount of 5-10% by volume of the basics - Vaseline or baby oil, oxolinic ointment.

If the nose accumulated thick isolation yellow green solution was used for washing the nasal passages. The procedure is performed in the doctor-patient conditions. Unprofessional approach to the washing can cause enhanced swelling, irritation of the mucous layer. Duration, intensity of each type of treatment is determined individually by the physician.

How to use the solution inside with SARS?

Antiviral efficacy of prophylactic and therapeutic effect in influenza ACC, respiratorno- viral lesions proved scientifically and practically. 5% solution, in a similar tablet dosage prevent the penetration of pathogens in cell nasal structure, prolonged retard or inhibit their reproduction is not allowed to develop complications.

Herpes drug inhibits also virions, which are activated in cold conditions weakened immunity. The simultaneous use of antivirals Amizon, Tamiflu creates a synergistic effect, increasing the effect of acid allows lower dosages of each drug.

Aminocaproic acid, instructions for use which is described below, is used both internally and topically. For 5% solution of 1 g of powder is stirred with 2 tablespoons sweetened warm water.

Therapeutic dosing according to body weight:

• 5 kg - 2.5 ml solution of either 0.123 g of powder;
• 10 kg - 5 ml - 0.25 g;
• 15 kg - 7.6 mL - 0.38 g;
• 20 kg - 10 mL - 0.5 g;
• 25 kg - 12.5 mL - 0.63 g;
• 30 kg - 15 ml - 0.75 g;
• 35 kg - 17.5 mL - 0.88 g;
• 40 kg - 20 ml - 1 g;
• 45 kg - 22.5 mL - 1.13 g;
• 50 kg - 25 ml - 1.25 g;
• 55 kg - 27.5 ml-1.38 g;
• 60 kg - 30 mL - 1.5 g;
• 70 kg - 35 ml - 1.75 g;
• 80 kg - 40 ml - 2 g;
• 90 kg - 42.5 mL - 2.25 g;
• 100 kg - 50 mL - 2.5 g

These unit volumes repeated 4 times a day. In severe pathogenesis dose increase on prescription. Practiced combination of oral and intravenous process-drip.

The use in a nebulizer for inhalation in adenoids

Inhalation via nebulizer make even infants. For this fit quiet electronic device, such as an ultrasound. The compressor unit is used for older children, who are not frightened by his noisy work.

Nebulizer drug from creates a fine mist. This allows for easy breathing, rapid absorption of the drug into the inflamed tissue of children and adults. ACC does not dry mucous, after it does not require additional humidification.

Aminocaproic acid (instruction manual involves exchange treatment means) diluted in equal proportions with saline or with non-hot distilled water is poured into a container for a medicament facilities.

On the face mask is worn on the device for 5-10 minutes. The day is held on 1-2 procedure. Duration defines ENT physician based on the primary and repeated examinations tonsil state.

Cautions: during pregnancy, for children

The drug is prohibited for pregnant women, nursing mothers. He allowed children of any age to perform all prescribed procedures, but under the strict supervision of a pediatrician, children's ENT.

Overdose

Do not exceed the recommended dosage, to self-medicate. Given ACC property to inhibit liquefaction of clots, thrombus formation face overdose, vascular occlusion.

Unreasonable extension rate of more than 6 days, the use of large daily doses of 24 g per day (for adults) increases the risk of hemorrhage.

Upon the occurrence of adverse reactions treatment is stopped, being symptomatic therapy.

Interaction

Aminocaproic acid, instructions for use which contains a lot of evidence, is well combined with glucose, hydrolysates, anti-shock means. When this is not permitted direct mixing aminocaproic solution with other drugs.

Reduce the effectiveness of antiplatelet therapy, ACC, the direct and indirect anticoagulants, which thin the blood, preventing the formation of fibrin plugs for the broken vessel.

Not recommended use of an acid simultaneously with the pill because of increase of blood clotting.

Storage conditions

Unopened bottles, bags, containers with aminocaproic acid are not stored for more than 3 years in a dark, dry place. Temperature range should not exceed 1-20 ° C.

After opening, the vial with solution for internal use at room temperature for 7 days pass in a refrigerator - 10 days. The opened container dropper installed in a rack immediately.

The use of the delayed liquid, as well as slurries, flakes, sludge is unacceptable!

analogs

Aminocaproic acid can replace other drugs whose instruction is similar in use.

This remedies the same hemostatic, inflammatory, antiallergic action based on aprotinin, tranexamic acid or aminomethyl - Azeptil, Gemotran, Tranexam, Tramiks, Pamba, Gumbiks, Contrycal, Polikapran.

Price in Moscow, St. Petersburg, regions

Aminocaproic acid is inexpensive, the cost of the capital cities and the periphery varies within a narrow range. Examples of price variations are shown in the table.

City	price, rub.
Moscow	58-23
SPb	32-44
Astrakhan	33-38
Barnaul	35-48
Blagoveshchensk	47-55
Volgograd	27-54
Yekaterinburg	39-48
Izhevsk	32-37
Kazan	26-56
Krasnodar	25-60
Krasnoyarsk	42-56
Permian	36-51
Rostov-on-Don	31-45
Saratov	33-45
Tolyatti	33-43
Ufa	34-50
Yaroslavl	32-38

Reviews of doctors and patients

Otolaryngologists, dentists, surgeons rely aminocaproic acid and complex treatment of lung disorders, diseases. In their review, the same opinion on the effectiveness of the drug with viral rhinitis, sinusitis, inflammation of the nasal mucous layer, oral cavity, gums and various bleedings.

Doctors believe the ACC the most secure, affordable compared to similar products.

Parents of young children, adult patients who used different forms of aminocaproic acid, indicated in their comments that the solutions, tablets, powders, transferred normally act quickly, bringing relief from the ENT diseases, during the development of a viral infection, during convalescence after surgery.

Application of ACC did not show immediate or distant negative at the end of the treatment course.

The accolades marked Protective result of the prophylactic use. It does manage to resist the flow of viruses in transport, at work from sick people. 5% of the acid solution to help extinguish the gingival inflammation arising after extraction.

It gained in the mouth to the affected area received a healing bath for a few minutes. For a week the wound safely delayed.

In pharmacies, there are no ready aminocaproic nasal drops in the respective bottle with a dropper. We have to buy a solution for intravenous lines, and it's a lot of volume, it is inconvenient to use.

Aminocaproic acid, according to the instruction, is easy to use and is considered safe means, However, the leadership in the treatment of any disease should be only the direct use of the drug doctor.

Registration of the article: Vladimir the Great

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