Choose between ceftriaxone and Tsefotaksinom does the doctor, but patients often ask what is better: ceftriaxone or cefotaxime. Very often people ask if the treatment of the same disease Cefotaxime was administered first, followed by ceftriaxone. To answer the question you need to consider the similarities and differences between drugs.
First, the similarity
Both drugs are broad-spectrum antibiotics and are used for the destruction of pathogenic bacterial flora.
General characteristics
Ceftriaxone, cefotaxime and is considered to be an analogue drugs have similar characteristics:
- refers to a preparation of several tsefalosparinovogo III generation;
- destroying microorganisms identical;
- gemoplatsentarny penetrate the barrier and are excreted in breast milk (with caution must be taken during pregnancy and lactation);
- Allowed to treat bacterial infections in the newborn;
- Injectable solutions are prepared prior to administration, and do not store more than 6 hours (reduced effectiveness of the medicament);
- prick do 1-2 times a day at a time;
- carefully administered in conjunction with other antibacterial drugs groups (between application Cefotaxime or ceftriaxone and other compatible tsefalosparinami antibiotics must be at least hours).
Ceftriaxone and cefotaxime well tolerated, rarely produce adverse reactions, but the treatment should not exceed 7-10 days.
The difference between the drugs in small price: 1 bottle worth Ceftriaxone or Cefotaxime with a single dose injection of 15-21 rubles.
Indications for use
Cefotaxime or ceftriaxone administered in the following diseases caused by bacterial microflora:
- tonsillitis;
- pharyngitis;
- otitis;
- sinusitis;
- pneumonia;
- acute or chronic renal disease;
- urethritis;
- cystitis;
- exacerbation of prostatitis in men;
- pelvic inflammatory disease (endometritis, adnexitis et al.);
- puerperal infection;
- inflammation after abortion;
- sexually transmitted diseases;
- meningitis;
- salmonellosis;
- intestinal infections;
- sepsis;
- purulent inflammation of the skin.
As cefotaxime or ceftriaxone substitute indicated for the prevention of postoperative complications.
The ban on the use of
As cefotaxime, ceftriaxone is forbidden to assign the following conditions:
- intolerance active drug component;
- renal failure (drug excreted in urine);
- acute or chronic liver disease (slowing excretion of the drug and perhaps the development of an overdose);
- krovorazzhizhayuschih reception means (antibiotics may provoke bleeding);
- first trimester of pregnancy (at later timing according to indications may use Cefotaxime Ceftriaxone or for the mother);
- hyperbilirubinemia;
- recent myocardial infarction;
- heart failure;
- alcoholism;
- epilepsy;
- irritability.
Sometimes prescribed stabbing cefotaxime and ceftriaxone mother breast feeding a baby, but pharmacological reference books indicate that the compatibility of breastfeeding and antibiotic treatment is not possible. But breast milk is allocated a small amount of active ingredients of a medicament, so doctors are allowed to feed her baby healthy during treatment of the nursing mother.
Adverse reactions
Cefotaxime and ceftriaxone have the same effect on the body, so the side effects of antibiotics are the same.
It is recommended to stop taking drugs if there were the following side effects:
- nausea and vomiting;
- violation stool (diarrhea or constipation);
- goiter;
- loss of appetite;
- stomach ache;
- itching in the perineum (the anus and the genitals);
- joining a fungal infection (stomatitis, thrush);
- anxiety and irritability;
- sleep disturbances;
- headache;
- inflammation of the conjunctiva of the eye.
The most dangerous side effect is the development of anaphylactic shock, accompanied by loss of consciousness and a sharp decrease in blood pressure. Without medical assistance shock are fatal.
Because of the risk of side effects of treatment with drugs is carried out in a hospital. Admission Cefotaxime or Ceftriaxone without a doctor's appointment invalid.
Possible complications after antibiotic therapy
Cefotaxime and ceftriaxone with blood penetrate into all tissues of the body, destroying not only the pathogenic bacteria but also beneficial micro-organisms.
The death of beneficial microflora is accompanied by digestive disorders:
- dyspepsia;
- epigastric pain;
- flatulence and bloating;
- reduce appetite.
In order to prevent disruption of the digestive tract in patients receiving antibiotics additionally prescribe drugs to restore the intestinal microflora (Bifidumbacterin, Atsipol, Hilak Forte).
In severe infectious processes, to prevent possible side effects, patients treated simultaneously administered both drugs - cefotaxime and ceftriaxone. Despite the fact that the medicaments are analogues and have similar effects on the body, they have different compositions. The combined use of cefotaxime and Ceftriaxone help suppress the inflammatory process faster.
Aware of the differences
Despite the fact that the antibacterial agents are considered to be peers, there are differences of Cefotaxime Ceftriaxone:
- Active substance. Cefotaxime contains an active component Cefotaxime, Ceftriaxone and - Ceftriaxone sodium salt. The active components are different in chemical composition;
- Diluent powder. For intravenous use, the two antibiotic diluted with 0.9% sodium chloride solution and administered slowly;
- The incidence of side effects. According to statistics, cefotaxime often produces undesirable reactions and Ceftriaxone easily tolerated by patients;
- Efficiency. Cefotaxime acts weaker, so for serious infectious processes, is best given Ceftriaxone.
After consideration of the difference of Ceftriaxone Cefotaxime can be concluded that both the drug are different only in composition. If necessary, without prejudice to the therapy, it is possible to replace ceftriaxone cefotaxime.
What is better to choose
If we compare with cefotaxime ceftriaxone for treatment effect, the difference in the choice of drug for the treatment of diseases of the middle the severity and sometimes no specialist can offer to replace Cefotaxime Ceftriaxone, if specified in the prescription drug is not pharmacy. But, despite the fact that the replacement of the drug does not affect the quality of treatment before use should consult a doctor.
The reason may be as follows for the appointment of a specific antibiotic:
- The severity of infection. Tseftiakson compared with cefotaxime is more effective in the fight against pathogenic microorganisms, and in severe inflammatory process will help overcome the disease faster;
- Portability. Some patients experience an allergic reaction to cefotaxime, ceftriaxone but it is well tolerated and is suitable for treatment. If a history of allergic reaction to one of the antibiotics, the replacement is not permitted;
It is impossible to say better than cefotaxime or ceftriaxone. Both antibiotic helping to cope successfully with infections caused by bacterial microflora.
Found a bug? Select it and press Ctrl + Enter
