Pulmicort inhalation for adults - hormonal medication. His release in the form of a suspension or a powder for nebuliser in Symbicort, but with more than children, dosage. The facility has a number of advantages, especially the use of precautionary rules.
Description Medicine
Pulmicort is made in Sweden. The preparation is intended for the preventive and base treatment of asthma of whatever type, if the disease should be treated by hormonal agents. The second indication for inhalation is a chronic obstructive pulmonary disease.
In addition to asthma and COPD Pulmicort doctors prescribe to relieve symptoms of:
- hay fever;
- allergic laryngospasm;
- emphysema;
- bronchitis with obstruction;
- other stenotic diseases of the respiratory system;
- respiratory deterioration due to spasm, dry cough.
Pulmicort inhalation via nebulizer to help cope with allergic rhinitis. In this disease as suspension may be diluted with physiological saline and instilled into the nose.
Composition of Medicine
Pulmicort belongs to inhalants. The active component is a glucocorticosteroid budesonide. The substance is introduced into a classifier ATC cipher R03BA02 «Budesonide».
As part of Pulmicort for adults contains budesonide:
- 1 ml of the suspension - 0.5 mg (recalculated equals 500 micrograms);
- 1 in a dose of powder turbuhaler - 200 micrograms.
Together with the drug substance in the suspension is citric acid, sodium chloride and citrate, disodium edetate, a preservative, a solvent, polysorbate (Tween) 80. In the inhaler Symbicort in a separate tank is also a powder dryer.
action Medicine
In budesonide revealed anti-allergic, anti-inflammatory and antiekssudativnoe property. The substance is not addictive, but the drug can be used without interruption from 3 days to 2 months. Short-term courses of inhaled are not allowed to develop systemic side effects of glucocorticoids. Stenotic disease symptoms disappear completely after 1-2 weeks of therapy completion.
Pulmicort inhalation contribute:
- expanding the airway lumen;
- allergic excretion secretion fluid and phlegm from bronchi;
- reducing the severity of asthma symptoms;
- prolongation of remission;
- decrease in the sensitivity of respiratory membranes to pollens, allergens or other irritants;
- suppression of inflammatory mediators, causing relieves swelling and pain.
Important! Pulmicort inhalation for acute bronchospastic reactions do not recommend the use of slow-motion effects of budesonide. Spastic portion relaxes after a couple of hours after the procedure.
Medicine restrictions
Pulmicort for adults, another drug with a cipher R03BA02, forbidden to appoint a high sensitivity to budesonide. Inhalation override in case of allergic reactions, glucocorticoid systemic manifestations.
Pulmicort is used with caution to patients:
- pulmonary tuberculosis;
- oropharyngeal candidiasis;
- infectious respiratory diseases of any etiology;
- glaucoma;
- cirrhosis;
- renal pathologies.
Self glucocorticoid contraindicated in lactating women, or to bear a child. During pregnancy and lactation budesonide inhalation make compliance with medical recommendations.
advantages of Medicine
In the topical treatment Pulmicort Turbuhaler or nebulized budesonide delivered directly to mucosal respiratory penetrates the membrane of the cells. Inhalation increase the ability of assimilation of substances: bioavailability is 90-100 micrograms to 250 micrograms of each (about 38-40% dose used).
Other advantages of Pulmicort:
- It does not cause addiction;
- minimal risk of systemic manifestations of budesonide;
- the combined treatment did not reduce the properties of other drugs.
Powder / Pulmicort solution for inhalation can be used at any temperature. A method for use of the drug does not affect the fluctuations in the indicator. If it is above 37.5º C, you can not only breathe over the steam or to carry out other procedures warming.
Features of treatment of pregnant women
Research on animals has confirmed embryotoxic, teratogenic effects of budesonide. Progeny born with congenital anomalies, so physicians during gestation women avoid treatment of systemic drugs.
When inhaled Pulmicort unknown effects on the body of pregnant women and fetal. Clinicians are not observed embryotoxic and teratogenic effects in patients. Controlled studies of women after conception have not been conducted.
Pregnant women with asthma or COPD, inhalation Pulmicort prescribed if other drugs do not help. To prevent a possible violation of fetal development, expectant mothers prescribed minimum dosage.
Features therapy nursing women
Studies have confirmed the ability of budesonide penetrate in human milk during the application of systemic drugs. A child at feeding swallows the medicine, which made it possible occurrence of negative effects of glucocorticoids. Clinicians have observed no such action after inhaled glucocorticosteroids Pulmicort lactating women. But As a precaution, the period of treatment is recommended to transfer the baby to artificial nutrition. In case of cancellation does not need breastfeeding dosage adjustment.
Features therapy adolescents over 12 years
When inhaled budesonide may slow down the growth of a teenager (or any other age of the child). Violation reversible. Pulmicort treatment requires periodic verification of this figure with the norms of physical development of children.
Many drugs adolescent therapy is an adult dosages. Pulmicort to such medicines does not apply. According to the standard of 18 years when used turbuhaler per day administered 100 .mu.g-800 .mu.g of budesonide / day. Adults maximum rate of 1600 mg. The suspension was administered in a dose adolescents 0.75-2 mg / 24 hours, with 18 - to 4 mg. During the day, do 1-4 inhalation.
dosing Medicine
In adults, no age limit Pulmicort dosage. The daily rate for inhalation does not need to adjust the treatment of the elderly.
Pulmicort adult per day administered during:
- treating bronchospastic reactions - 1-2 mg of suspension, 200-1600 mcg powder;
- maintenance therapy - at 0.5 mg-4 mg (up to 8 ml), 200-800 micrograms.
The daily dosage of 1 ml / 400 g or less is allowed to use a single inhalation. If the amount of Pulmicort than 1 ml or 400 ug, prescribed rate is recommended to divide for 2-4 treatments. They conducted the night, in the morning or at regular intervals: every 4 h, 6 h, or 12 hours. The course of treatment is 3-14 sessions. The duration of maintenance therapy indicated by the doctor.
Precautions and methods of use
Before the start of the application of Pulmicort women of childbearing age need to do an analysis of hCG or pregnancy test. During treatment it is necessary to use reliable contraception.
If inhalation is combined with systemic hormonal agents, glucocorticoids adjust dosages to avoid the accumulation of corticosteroids in the blood. For the failure of injections and tablets gradually reduce their number. Pulmicort norm is increased from 0.5 mg / 200 mcg administered once or large, gradually leading to the minimum effective amount of budesonide.
Pick up a combined system and the dose should be a doctor, because the matter:
- itraconazole, erythromycin - increase the effect of budesonide;
- methandrostenolone - enhances the systemic effects of corticosteroids;
- phenobarbital - Pulmicort effect worsens;
- ketoconazole - increases the toxic properties of budesonide.
Inhalation do sitting, after a half hour after eating, vigorous exercise. In the second half of the session on the need to tap the reservoir of the nebulizer medication for agitation. After the procedure is not recommended to eat, drink and talk for 30 minutes. Since the substance has time to be absorbed more easily manifest dysphonia.
After inhalation Pulmicort carefully rinse the mouth and spit water. If a procedure mask was used, as it is necessary to wash. These measures warn caution oropharyngeal candidiasis, contact dermatitis on the face.
How to use powder
Breeding Pulmicort is not necessary for inhalations Symbicort: mucous should hit a dry powder. Micronized substance is not felt in the membranes of the oropharynx or bronchus.
Instructions for Pulmicort inhalation powder:
- With the bottle cap is removed.
- Take turbuhaler vertically to the dispenser "staring" at the floor.
- Once crank dispenser until it stops against the move clockwise and immediately back until a click is heard.
- Exhaled air, hold their breath.
- Take the mouthpiece into your mouth, leading him closer to the throat.
- Holding the mouthpiece through his teeth and slightly parted lips deeply and sharply inhaled breath.
- Is delayed by 10 seconds of breath.
- Control the mouthpiece from his mouth, nose exhale away from turbuhaler.
- Close the vial with a dry cloth wipe the mouthpiece.
If Pulmicort appointed 2-4 doses per inhalation, during the procedure is repeated 2-4 times steps 2-8. The mouthpiece should not be wet! Medicine in Symbicort ended when the red band touched the lower edge of the indicator window.
Dosing suspensions
The slurry is intended for inhalation nebulizer compressor with a tank volume of 2 ml. Ultrasonic devices are not able to spray the medicine.
Adults for Pulmicort nebulizer suitable dose of 0.5 mg / ml. If for a single inhalation prescribed by 0.75 mg, 1.25 mg, and so on, it is more convenient to use the children's suspension - 0.25 mg / ml.
For normal operation of the nebulizer in the tank must be at least 2 ml of fluid. For inhalation need to purchase Pulmicort instructions allowed in the solvent at a single dose of 1 ml. During the preparation process is connected to the 1 ml of the suspension and 1 ml of saline.
Instructions for inhalation nebulizer:
- Shake containers of medicine, put them vertically: nebulium neck upwards.
- Crank axis nebulium one without squeezing the container wall.
- Extruded into a clean dry tank nebulizer desired quantity for one inhalation suspension. If necessary, add 1 ml of saline solution and stir.
- Close the tank, the device is connected compressor.
- Tightly pressed to the face mask or mouthpiece is inserted into the mouth include unit.
- Pulmicort breathe through nebulizer should be calmly, deeply, without sharp retraction of the air. Mouth inhale, hold their breath for about 10 seconds, exhale nose.
- When the liquid in the tank evaporates, inhalation stopped.
Procedure lasts about 15 minutes. After inhalation clean tank unit mask according to the operation requirements.
On a note! If a medicine remains nebula, slurry the residue kept until the next inhalation in the refrigerator and used no later than 12 hours after opening the container. Ready Pulmicort nebulizer solution fit a maximum of 30 minutes.
Important
Overdose Pulmicort appears only hypercortisolism, adrenal hypofunction and confirmatory analyzes. Rash, nausea, headache, bronchospasm and angioedema indicate hypersensitivity or intolerance to budesonide. In these cases, doctors need help, the replacement drug for inhalation.
sources:
Vidal: https://www.vidal.ru/drugs/pulmicort__1801
GRLS: https://grls.rosminzdrav.ru/Grls_View_v2.aspx? routingGuid = 298bc255-c163-4775-8082-11b258936afc & t =
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