A positive result on the CMV IgG indicates that human developed immunity to the virus, but it is its carrier. But this is not always linked to any danger. The only option that can result in serious negative consequences - negative impact on the development of the fetus during pregnancy.
The content of the article:
- 1 types of diseases
- 2 Stage and grade
- 3 symptoms
- 4 Causes of
- 5 Indications for study
- 6 How to determine the
- 7 Preparation and analysis
- 8 Decoding results
- 9 How to bring back to normal
- 10 Videos about treatment tsitomagelovirusa
types of diseases
cytomegalovirus infection It carries a mortal danger for several special groups of people:
- transplant recipients;
- HIV-infected;
- pregnant women;
- newborn babies.
As long cytomegalovirus may be present in the body and does not manifest itself in a number of cases for no apparent reason begins an unexpected increase in malignancies, carcinomas mukoepidermoidnoy and other violations of a similar degree gravity.
Currently, the disease is divided into several types and forms:
- generalized;
- congenital;
- sharp.
Each different type of symptoms, signs and course.
Stage and grade
The incubation period after the penetration of the pathogen infection in the human body is 20-60 days. In the future, begin to grow the symptoms of the acute phase, which lasts 2-6 weeks. The latent form is preserved indefinitely.
However, even a full course of treatment is not able to completely withdraw pathogen from the body had been ill man. That is why doctors do not give any guarantee against a possible relapse in the period of gestation is the woman of the future child.
symptoms
CMV IgG positive in generalized form refers to severe conditions arising on a background flow of other diseases. Diagnosis in this case is difficult because of a combination of several bacterial infections and the presence of abnormalities of functioning of the body.
Among all investigated CMV disease is most often masked the symptoms of SARS usual:
- temperature increase;
- appearance of rhinitis;
- sore throat.
But the symptoms persist for a month or even more of cytomegalovirus infection. Therefore, when such a course of the disease should consult a physician and referral for more detailed examination. It will determine the time of infection and age.
Congenital form is recorded when the infection occurred in the womb. In most cases, a woman may not be aware that she is a carrier of infection and dangerous in terms of transmitting the virus to her child.
Therefore, after the birth of approximately 1 in 10 neonates recorded following CMV infection symptoms:
- seizures;
- inflammation of the retina;
- formation of calcifications in the brain;
- hepatosplenomegaly;
- signs of microcephaly;
- prematurity and intrauterine growth retardation;
- rash on the body, arms and legs.
The acute form immediately after birth leads to the development of symptoms, which persist up to 1.5 months.
It is often observed the following symptoms:
- general deterioration of health;
- severe pain in the head;
- muscle soreness;
- hyperthermia;
- sweating;
- chills.
Thus, in the process of performing a blood test, a large number of registers abnormal cell structures. Cytomegalovirus IgG positive specific type - a latent form. In this case, leakage asymptomatic or subclinical.
Of particular importance accurate diagnosis for children, who tend to frequent infectious diseases:
- pyelonephritis;
- pneumonia;
- sinusitis;
- bronchitis;
- cystitis;
- otitis.
According to statistics, cytomegalovirus infection is found in 70% of children are constantly ill.
Causes of
Ways of transmission of cytomegalovirus very different, since it is contained in the blood, saliva, milk, urine, feces, semen, secretions from the cervix. It is also possible to transmit airborne droplets.
One of the most important values - transmission of the virus from the mother at birth and during breastfeeding. In some cases, the carrier of the virus may not be aware of their condition throughout their lives, yet remain highly infectious to people around them.
When carriers of an infection in the body starting point run aggravation may become several factors:
- seasonal weakening of immunity;
- surgery;
- promiscuous;
- prolonged hypothermia;
- malnutrition;
- disease and stress.
If insufficient power is varied reason may be due to lack of lysine - a substance that helps combat disease.
Re-recurrence can be avoided by constantly engaged in strengthening the immune system, to observe the day and night mode rest as you can spend more time in the fresh air long enough to relax and generally lead a healthy life.
Indications for study
CMV - a herpes type 5. As is known, all types of herpes is extremely contagious, and the primary contact with the pathogen results in its life to the presence in the human body. By the age of 18 years, the number of infected reached 50%, and to 50 years - already 98%.
Therefore, the appearance of any symptoms of the above are advised to contact a physician and undergo a series of necessary surveys. Upon confirmation of the diagnosis will have a chance to avoid complications in the event of a sudden activation of the infection under the influence of provoking factors. This is especially true of women who are planning in the future of children.
How to determine the
The present level of diagnosing the presence and degree of activity of cytomegalovirus infection has reached considerable heights. In order to determine and confirm the activity of the virus using several techniques.
They allow you to confirm or rule out the following facts:
- tentative dates after the penetration of the pathogen;
- the presence or absence of the virus in the human body;
- the current stage of infection.
Additional techniques especially popular following:
-
Molecular biological techniques. Polymerase chain reaction helps determine the composition of the blood in the presence of herpesvirus type 5. Among other advantages, the fact that this analysis can identify infection penetration path, the current stage of the disease and some other indicators.
- Linked immunosorbent assay. It refers to methods that assess specific antigens reacting with antibodies. Evaluation of the complex formed is performed using an enzyme as a specific mark.
- Virological Method. By seeding material selected method can determine the presence of the pathogen, even in small concentrations. Not too high popularity due to the fact that the results have to wait at least 1 week.
- Indirect immunofluorescence. By this method is obtained to determine the approximate period of carriage of cytomegalovirus infection.
Choice of techniques for the diagnosis of a doctor should do, immunologist, virologist. He will evaluate current symptoms, their severity, and associated complaints. CMV IgG positive or negative is detected by standard sampling venous blood sample. This is followed by analysis of the definition of the research results.
Preparation and analysis
As necessary training recommend a number of rules that will result in significant performance:
- blood samples to CMV produced on an empty stomach, so the interval between the last meal and the analysis of the delivery must be at least 6-8 hours;
- during this period allowed to drink water without added sugar or other sweeteners or honey type jam;
- except for sugar, it is necessary to 1 day to reduce or refuse the use of fatty foods;
- to the data may affect the menstrual cycle phase, so the question should be discussed with your doctor;
- Some drugs also can distort the results of the survey;
- high physical exertion and stress situations can lead to incorrect data;
- 1 day prior to sampling analysis is recommended to refuse the use of any alcoholic beverages.
The last and essential condition - stay in a fixed position at least 15 minutes before starting the analysis.
Decoding results
Additional indicators that can identify the analysis, detecting the presence or absence of several antibodies.
| IgM | These immunoglobulins are beginning to be developed in 5-7 days after virus infection |
| IgG | This variant is detected after 2-3 weeks and lasts for the entire life |
| IgG avidity | Indicator provides a measure of limitation of infection |
Increasing the amount of IgG indicates activation and pathogenic processes requires assignment of effective therapy. Testing is usually carried out in the event that it was reported the presence of immunoglobulin type IgM. Sometimes the analysis is assigned, even in case of a negative IgM, to confirm the absence of infection with cytomegalovirus.
Low avidity IgG indicate the period of 3-4 months after infection. After that, instead of them always found high avidity antibodies. This result is particularly important in some cases, for example, for the diagnosis of infection in pregnant women.
How to bring back to normal
Treat the person is recommended only when the disease can lead to serious consequences for the organism. Of particular need for treatment may be noted for a generalized form. Driving therapy can only be assigned to a specialist after a personal consultation, examination and investigation.
Basic medicines are recommended for treatment, are divided into several groups:
- Symptomatic drugs are cropped disease processes, inflammatory reaction vessels constrict;
- immunomodulators stimulate the activity of its own immunity in an infected person;
- immunoglobulins bind and neutralize virus particles;
- antiviral agents inhibit infection activity;
- vitamins and minerals contribute to recovery.
Ie, the treatment in this case is always multifaceted and complex. Single scheme that can be applied to any victim, no. CMV IgG in the case of a positive result of the analysis can not be derived from the body only through them.
However, traditional methods of support the immune system and promote healing:
- decoction Echinacea effectively fight germs and viruses, strengthens the defenses of the human body;
- medicinal herbs, wild rose, raspberry, violet, nettle and others contribute to the restoration;
- licorice root contains glycyrrhizic acid, which has an antiviral effect.
In the latter case, you can use ready-made syrup of licorice, which is sold in every drugstore and is quite inexpensive. Its use is recommended for coughs, but glycyrrhizin acid refers to the active substances to enhance immunity against a variety of other pathologies.
Further active agents, carefully recommended vitamins and minerals. Ascorbic acid should constantly come in sufficient quantities. Folic acid or vitamin B9, is also needed.
Its consumption contributes to the growth and development of blood vessels and strengthening the immune system. But it is recommended not to exceed the normal dose, as in this case a decrease in the activity of natural killer cells.
In extreme cases, it may be recommended hospitalization of the patient in the hospital. But it is important to remember that a person during illness is highly infectious to people around them. Therefore, any contacts should be strictly limited.
CMV IgG at a positive result after the test - it's not as scary as it may seem at first glance. But some precautions and strengthen the immune system will have to take. In this case, neither the man nor others do not suffer from the disease-causing viruses at the competent approach to the treatment and prevention of the spread of infection to other people.
Registration of the article: Vladimir the Great
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