Omeprazole: instructions for use, real prices

Omeprazole - current medications used to treat ulcers and erosions of the upper GI, including inflammatory disorders. Omeprazole has an inhibitory effect on the process of production of hydrochloric acid in the stomach.

Only once in the acidic gastric environment, the drug exerts its properties - reduces the effect of acid on wall bodies, restores the acid-alkaline balance of the gastric juice, reduces symptoms diseases. Upon receiving this drug in patients not only improves health, but also decreases the risk of contracting again. The first action is felt for an hour and continued for 24 hours.

Release form and composition

The dosage forms of omeprazole release:

• Enteric capsule (7, 10, 14 or 15 pieces. in blisters, at 1-5, 8 or 10 packs in a cardboard bundle; 14, 10 or 30 pieces. in polymeric banks Bank 1 carton pack; 20, 30, 40, 50, 100 pcs. in polymeric containers 1, 10, or 20 containers in a cardboard package).
• Capsules: gelatin solid, opaque, size 2 №; housing - white cap - red; capsules contain white spherical pellets with a cream shade or white (7 pcs. in blisters, 2-4 packing in a cardboard bundle; 10 pcs. in blisters, 1-3 packing in a cardboard bundle; 15 pcs. in blisters, for 1-4 packing in a cardboard bundle);
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The enteric capsule composition 1 includes:

• Active substance: omeprazole - 20 mg;
• Additional components: sodium carboxymethylstarch (type A), povidone K-30, sodium hydroxide, a copolymer of ethyl acrylate and methacrylic acid [1: 1], titanium dioxide (E171), nibs sugar (glucose syrup, sucrose), sodium lauryl sulfate, sodium phosphate dodecahydrate, hypromellose, triethyl citrate, talc;
• Gelatin capsule (body and cap): titanium dioxide (E171), gelatin, water.

The composition of one capsule contains:

• Active substance: omeprazole - 20 mg;
• Additional components: titanium dioxide, sodium lauryl sulfate, gelatin, Nipagin, Nipasol, glycerin, coloring agent E 129, purified water.

What is prescribed Omeprazole?

Indications for use of omeprazole Acre do not differ from the readings, which are listed in the summary Omeprazole produced by another pharmaceutical company (Sandoz, Gedeon Richter Plc., STADA CIS and etc.). The medicine is effective for:

• GERD;
• amelioration of symptoms of acid dyspeptic disorders (drug helps with heartburn, eliminates the severity of abdominal pain, belching, bloating, flatulence, nausea and the unpleasant taste);
• Prevention of aspiration of acidic gastric contents;
• ultserogennoe PZHZH adenoma;
• benign ulcers of the stomach / intestine tiperstnoj 12 (including, if the disease is associated with a NSAID);
• eradication therapy H. pylori (in combination with anti-bacterial drugs).

From what helps omeprazole (Acre, STADA, Sandoz, Richter and others.) With these diseases? A drug acting at the molecular level, inhibits the synthesis of hydrochloric acid parietal cells of the gastric mucosa and prevents increased secretion after meal. Thus, in the treatment of omeprazole has been rapid regression caused by the acidity of the infringement diseases of the stomach and / or 12-tiperstnoj intestines, symptoms of dyspepsia and pain go away, improves overall health.

Causing persistent decrease acidity drug creates optimal conditions for successful eradication N.pylory, which is the cause of 90% of gastritis and peptic ulcer.

Contraindications

Be wary appoint patients with renal or hepatic insufficiency. The instructions for use of omeprazole given absolute contraindications to treatment:

1. Pregnancy;
2. Lactation;
3. Childhood;
4. Hypersensitivity.

Side effect

The major side reactions that may occur when incorrect omeprazole, they are in the following symptoms:

1. Digestive system: the appearance of dryness in the mouth, the occurrence of diarrhea, candidal defeat of the digestive system, abdominal pain, functional impairment of normal activity liver, inflammation of the liver accompanied with jaundice, constipation, inflammation of the oral cavity organs, elevated liver enzymes, liver inflammation without concomitant jaundice;
2. hemopoietic system: rarely - leukopenia, agranulocytosis, thrombocytopenia, pantsitopepiya.
3. Musculoskeletal system: rarely develop myasthenia, arthralgia, myalgia.
4. Skin: in rare cases - itching or rash, photosensitivity, erythema multiforme, alopecia.
5. Allergic reactions: angioedema, rash, fever, bronchospasm, anaphylactic shock.
6. Central nervous system: dizziness, irritability, and various sleep disorders, the emergence of depressive states, the occurrence of hallucinations, multiple brain disorders, headaches, drowsiness, numbness in appearance limbs;
7. Other: rarely possible blurred vision, swelling of the limbs, malaise, sweating, gynecomastia, formation of benign gastric glandular cysts are reversible when long-term treatment.

Typically, the drug was well tolerated. The exception is the use of long-term - more than two months, but doctors do not prescribe medication for so long, the optimal course of treatment - 30 days. After the break, you can resume the use of a preventive measure.

Overdose

Overdose is extremely rare. It is known that increasing the dose, the patient can be alleviated, however, it should not exceed 60 mg per day. Otherwise, the possible complications of the following:

• tachycardia;
• confusion;
• Strong headache;
• slizystyh dryness of the mouth and nose;
• difficulty breathing;
• lost clarity of vision;
• drowsiness;
• increased sweating;
• the heat throughout the body.

When the above symptoms should immediately seek medical attention. He will appoint a symptomatic treatment - that is, will eliminate the consequences as they arise. Omeprazole is absorbed into the bloodstream within an hour - ie, dialysis is not effective.

Pregnancy and lactation

Pregnant women take Omeprazole is absolutely contraindicated. Nursing mothers taking omeprazole absolutely contraindicated.

Instructions for use

According to the instructions for use of a standard single dose of 20 mg of omeprazole, but it can be adjusted by the physician according to the disease and the general state of the patient weight. Omeprazole prescribed courses of no more than 2 months, then need a break for a few months.

1. When erosive and ulcerative esophagitis treatment is given similarly to gastric ulcer. As anti-treatment assigned 20 mg of omeprazole per day. The duration of treatment may be from 1 to 2 months.
2. In gastric ulcer in the acute stage Omeprazole administered 20-40 mg per day dose divided into 2 doses. The course of treatment - from 1 to 2 months.
3. When gastropathies and erosive-ulcerous lesions caused by non-steroidal anti-inflammatory drugs, assigned 1 capsule of omeprazole daily for a period of 4 to 8 weeks.
4. Ulcers duodenum 12 daily dose - 20 mg treatment - 2-4 weeks. For the prevention of recurrence of the disease on maintenance dose of omeprazole for up to 4 weeks. In this case it is necessary to use capsules containing 10 mg of the main active substance.
5. For the treatment of Helicobacter pylori infection by taking 20 mg in the morning and evening, the minimum rate - 7 days. Omeprazole in such treatment with antibacterial agents, one of the existing schemes always taken in a single unit (the triple or quadruple).
6. For the treatment of Zollinger-Ellison syndrome the dose of omeprazole is chosen strictly individually, depending on the initial level of gastric secretory activity. The minimum daily dose is 60 mg. Subsequently the dose may be increased to 120 mg / day, and the amount of the preparation is divided into 2 doses - in the morning and evening.
7. In patients with concomitant diseases liver daily dose should not exceed 20 mg.
8. For the prevention of wicking of acidic gastric content into the esophagus during long operations Omeprazole administered 40 mg before and 2-4 hours prior to surgery.
9. For relief of uncomplicated heartburn assigned omeprazole 20 mg once a day for 14 days. Repeated treatment is possible after 4 months.

In severe the patient's condition, especially if it is in the intensive care unit, omeprazole can be administered via catheter directly into the stomach, or to use sterile solutions for intravenous injections. For administration through the catheter needs 20 mg of powder from the capsule to dissolve in 30 ml of water, brew for 3-5 minutes and introduce gavage.

For intravenous drip 40 mg sterile powder omeprazole (1 vial) diluted with 100 ml of 0.9% sodium chloride or 5% glucose.

analogs

Because of its popularity and high efficiency of omeprazole has many analogues and generics (synonyms), which contain the same basic active substance, but substantially They differ in price.

The most popular analogues (synonyms) that are allowed in Russia:

• Bioprazol;
• Gastrozol;
• omez;
• Omefez;
• Ulzol;
• Omezol;
• Omeprazole Acre;
• Omeprazole-Richter;
• Losek;
• Losek CI (pellets);
• Gasek.

Also, there are other analogues of omeprazole, which are not registered in the Russian Federation:

• Gasek (Switzerland);
• Omeprazole-Astrafarm (Ukraine);
• Omeprazole-Darnitsya;
• Tserol (India).

At the pharmacy market in Europe is widely used Antra MAPS (Antra MUPS), Prilosec (Prilosec), Lokit, Proseptin, Romesek.

Omez or Omeprazole - which is better? What is the difference of omeprazole and omez?

The composition of omeprazole omez and includes the same active substance, that is the only thing that is different one drug from another, - the composition of the auxiliary components and the price (about twice as much Omez Omeprazole).

Responses indicate that both agents are equally effective in diseases of acid and equally well tolerated by the body: and Omeprazole, and analogue to quickly penetrate the gastrointestinal mucosa and is then absorbed into the blood within one hour reach maximum concentration and quickly eliminate the pain and discomfort stomach.

Reviews of omeprazole

Omeprazole tablets from the stomach - is an effective, quick and inexpensive means of an exacerbation of peptic ulcer disease, GERD, and a number of other acid-related diseases of the digestive system.

1. I have over 5 years suffer from chronic gastritis. It is not always possible to observe proper nutrition - work, children, husband, do not have time to prepare themselves individually. It turns out that from time to time intercept fatty foods, soon after which the attacks are exacerbated. I long ago my gastroenterologist advised to spend on drink a course of omeprazole - indeed, an effective tool! Before this took Ranitidine - but in order to feel relief, had to wait for a certain time, for about three days. Omeprazole acts immediately.
2. As a teenager, I had chronic gastritis. In one case, it began the terrible cramping pain in the stomach. I do not like to take medicine, but I had to. "Omeprazole" advised. Tablet drank on an empty stomach, 20 minutes after the pain is gone. Take 2 times daily 1 tablet. Propyl about four days and the symptoms do not recur. I liked very much the rapid action of the drug and a relatively very low cost.
3. I have for many years gastric ulcer, and when there is a period of exacerbation, immediately start drinking Omez. Of course, he instantly symptoms does not remove, but the situation gradually normalizes. Most importantly, drink the entire course, do not throw as soon as the symptoms go away, or not for long.

special instructions

Before the start of the drug is necessary to establish the correct diagnosis and rule out cancer.

Reducing the acidity of gastric contents from the descriptions manufacturers may provoke proliferation of pathogenic organisms. Do not exceed the dose and duration of therapy, said the doctor. Patients who suffer from severe liver disease is important to dose adjustment.

In most cases, omeprazole does not affect the ability to drive traffic. It is important to avoid such side effects as decreased vision, and confusion.

prices

The tablets of omeprazole price varies depending on the form of release, producer pricing policy, the number of capsules per box. Thus, 20 mg capsules №10 can be bought for 11-15 UAH, and the cost of packing №30 - from 27 UAH. Price omeprazole in form of a lyophilisate for the preparation of p-ra on / in the (fl. 40 mg №1) - from 103 UAH.

The price of omeprazole in Moscow and St. Petersburg - on 28 rubles. per pack №10 and 50 rubles. per pack №230. freeze-dried product price - from 235 rubles.

Conditions of supply of pharmacies

The drug is released under the prescription of the attending physician.