Content
- Release form
- Chemical composition
- Pharmacological properties
- Pharmacodynamics and pharmacokinetics
- Indications for use
- Contraindications
- At what age can the drug be used?
- Instructions for use, dosage
- For headache, toothache
- With gout
- With osteochondrosis, back pain
- During menstruation
- Side effects
- Overdose
- special instructions
- Drug interactions
- Analogs
- Aceclagin
- Aertal
- Asinak
- Terms, conditions of sale and storage
- Price
- Video about the active substance Aceclofenac
Aceclofenac (100 mg) is a drug, used in the treatment of disorders of the musculoskeletal system. The pill has a very affordable cost and numerous positive reviews.
Release form
The medicine is manufactured in Russia in the form of tablets for oral use. Description: white, round, biconvex. The product is packaged in contour cells and packed in cardboard boxes.
Chemical composition
The active ingredient is aceclofenac.
Additional composition:
- MCC;
- food additive E468;
- povidone K30;
- microgol;
- titanium dioxide;
- fall off (white);
- sodium stearyl fumarate.
Thanks to the combination of all the ingredients, the therapeutic effect of the medication is achieved.
Pharmacological properties
The drug belongs to the group of non-steroidal anti-inflammatory drugs (NSAIDs). Its action is aimed at suppressing the production of prostaglandins and cyclooxygenase, thereby achieving a pronounced anti-inflammatory and analgesic effect.
In case of joint diseases, the remedy leads to relief of pain syndrome, elimination of swelling and an increase in motor function.
Pharmacodynamics and pharmacokinetics
The suction level of the main component is high. Its maximum content in the blood is noted after 75-180 minutes. In this case, the maximum concentration of the substance in the synovial fluid occurs 2-4 hours later than in the blood. The content in the synovial fluid is 57%. The active ingredient interacts with proteins. The binding rate is 99%. The drug is partially metabolized and forms 1 major metabolite. The half-life of the drug is 4 hours. It is excreted mainly by the renal system.
Indications for use
Aceclofenac (100 mg) - tablets, the price of which is acceptable and affordable for most patients. The drug is used as a symptomatic treatment (including pain syndrome) for various diseases of the musculoskeletal and articular systems.
Indications:
- arthritis (rheumatoid form of the disease);
- pain in the lower back (lumbago);
- osteoarthritis;
- pain in the teeth;
- ankylosing spondylitis;
- rheumatism developing in the area of soft tissues;
- inflammatory processes in the tissues surrounding the joints of the shoulder or shoulder blades.
The medicine should be used only with an established diagnosis.
Contraindications
The tablets have some limitations, in the presence of which you should refuse to take them, since this can complicate existing diseases or lead to the development of additional disorders.
Contraindications:
- intolerance to the components;
- allergy to NSAIDs;
- the presence of erosions and ulcers in the stomach (exacerbated course of pathology);
- bleeding in the stomach;
- inflammation in the stomach;
- kidney failure (severe);
- kidney and liver diseases (active development of disorders);
- pathology of the thyroid gland;
- increased potassium in the blood;
- heart attack (acute form);
- chronic high or low blood pressure;
- rehabilitation after bypass surgery;
- stroke and other diseases characterized by impaired blood circulation in the brain;
- diseases of the blood and hematopoietic system;
- myasthenic syndrome;
- myopathy;
- pregnancy;
- lactation period;
- age under 18.
In these conditions, it is recommended to choose another drug.
At what age can the drug be used?
The drug is prohibited for use in children under 18 years of age.
Instructions for use, dosage
The product is used only orally. Dosage regimen: 100 mg 2 times a day (in the morning and evening). The duration of the course is no more than 1 week. For longer use, prior approval from a physician is required. In case of liver failure, the drug is taken once a day.
For headache, toothache
To relieve pain, 1 tablet is prescribed 1 time per day. Duration of treatment - once or as needed.
With gout
For gout, the medication is taken according to the general scheme. The duration of treatment is 1 week. In case of emergency, therapy can be extended. However, before that, you should first consult with a specialist.
With osteochondrosis, back pain
For these diseases, the medicine is used according to the general scheme. The duration of the course is 1 week. Treatment can only be extended with the permission of a doctor.
During menstruation
During menstruation, the medicine is taken according to the following scheme: 1 tablet 1 time per day to relieve pain. If necessary, with severe pain, the medicine is used according to the general scheme. The duration of therapy is 5-7 days.
Side effects
Aceclofenac (100 mg) - tablets, the price of which does not affect the risks of side effects. This factor depends on the physiological characteristics of the patient's body and is associated with the influence of active components. Adverse reactions are extremely rare.
Side effects:
- Lymphatic system: anemic disorders, functional disorders of the bone marrow, low content of leukocytes, neutrophils, platelets.
- Immune reaction: anaphylactic manifestations, hypersensitivity.
- Metabolic processes: increasing the concentration of potassium.
- Mind: disturbance, sleep, depression.
- Nervous system: the occurrence of dizziness, tremors in the body, paresthesia, increased drowsiness, migraines, changes in taste.
- Visual function: visual impairment.
- Hearing organs: ringing in the ears.
- Cardiovascular system: increased blood pressure, heart failure. In extremely rare cases, vasculitis, hot flashes, redness of the skin, a feeling of one's own heartbeat may occur.
- Respiratory system, chest: shortness of breath, spasms in the bronchi.
- Digestive organs: signs of dyspepsia, problems with stools, stomatitis (ulcerative form), gastritis, ulcers in the gastrointestinal tract, bleeding. In more rare cases, vomiting of blood, pancreatitis may occur, the course of ulcerative colitis and Crohn's syndrome may worsen.
- Liver and bile ducts: an increase in the activity of liver enzymes, liver pathology.
- Skin and subcutaneous tissue: signs of allergies, dermatitis, urticaria, eczema lesions, Quincke's edema, severe reactions.
- Urinary system: an increase in the concentration of urea and creatinine in the blood, nephrosis, kidney failure.
- General reactions: swelling, lethargy and weakness, muscle spasms.
- Other: increased body weight.
In the event of the development of these signs, as well as other symptoms not noted in the instructions, it is recommended to stop further taking the drug and seek the advice of a specialist.
Overdose
At the moment, no cases of drug overdose have been registered.
If the dosages prescribed by a specialist are exceeded, the following symptoms may develop:
- nausea and vomiting;
- dizziness;
- convulsive state;
- pain in the abdomen;
- headaches.
With the development of such symptoms, further use of the medication should be canceled and a doctor should be consulted for symptomatic therapy.
Treatment: intake of sorbents, gastric lavage.
special instructions
Aceclofenac (100 mg) should only be taken under the strict supervision of a physician, especially in certain patient groups. Tablets (the price of the medicine does not affect the risks of adverse or allergic reactions) must be used with caution and with the development of any negative manifestations from their reception, you must refuse and consult a doctor for consultation. After a series of examinations, therapy can be continued.
Be extremely careful when prescribing medication in the following cases:
- diseases of the kidneys, liver and stomach;
- ischemic heart disease;
- stomach ulcer;
- high blood pressure;
- bronchial asthma;
- hilicobacter;
- cerebrovascular disorders;
- low or high blood lipids;
- diabetes;
- smoking;
- damage to peripheral arteries;
- elderly people;
- somatic disorders;
- alcohol abuse;
- long-term use of non-steroidal anti-inflammatory drugs.
The drug requires careful administration to patients with renal and heart failure, individuals the elderly, using diuretics, as well as patients with increased volume circulating blood. When using the drug in this category of patients, it is necessary to periodically conduct studies of the functions of the kidneys, liver, blood. In some cases, the drug can lead to the development of dizziness, and therefore, it is necessary refuse to drive a car or carry out other work requiring the speed of psychomotor reactions.
Drug interactions
The medication can react with other drugs.
Medicines and action:
- Digoxin, phenytoin and agents containing lithium - an increase in the level of active components of the listed drugs.
- Diuretics and drugs that lower blood pressure - it is possible to reduce their therapeutic effect.
- Potassium-sparing diuretics - increasing the concentration of glucose in the blood. Blood sugar control is required.
- NSAIDs, glucocorticosteroids (oral forms) - an increase in the risk of side effects from the gastrointestinal tract.
- SSRIs increase the risk of bleeding in the stomach.
- Cyclosporine, tacrolimus - increased nephrotoxicity.
- Drugs that lower the concentration of glucose in the blood - a decrease or increase in the concentration of sugar. The glucose concentration must be monitored.
- Methotrexate - an increase in the level of the drug and its toxic effect.
- Aspirin - lowering the level of the main drug.
- Antiplatelet agents and anticoagulants - an increased risk of bleeding. A systematic study of blood functions is required.
- Mifepristone - a decrease in the effect of the drug (when taking the main agent less than 8-12 days before the start of therapy).
- Fluoroquinolones - an increased risk of seizures.
- Zidovudine - an increase in the risk of bleeding, bruising.
When using other drugs during the period of prescribing tablets, you should inform the treating person about this in advance. doctor, which will avoid drug incompatibility and, as a result, prevent the development of negative reactions.
Analogs
Aceclofenac (100 mg) - tablets, the price of which is not taken into account when choosing a similar drug. The cost of most substitutes is approximately in the same price range. It should be borne in mind that in some cases, the drug can lead to the development of intolerance reactions. If such effects occur, it is recommended to replace the agent with another drug similar in indications and action.
The selection of generics should be carried out by the attending physician, taking into account the severity of the course of the disease, the condition and other physiological characteristics of the patient. It is not recommended to prescribe and use substitutes on your own, since an incorrectly selected drug can worsen the condition and cause the development of additional complications.
Aceclagin
This tool is manufactured in Israel in the form of tablets for oral use, the active ingredient of which is aceclofenac. The medication belongs to the group of NSAIDs and is prescribed in the treatment of various diseases of the musculoskeletal system, as well as to eliminate pain.
Indications:
- headaches or toothaches;
- lumbago;
- rheumatism;
- inflammation of the soft tissues;
- arthritis;
- painful menstruation;
- osteochondrosis;
- spondylitis.
Dosage regimen: 1 tablet (0.2 g) 1 time per day. The duration of the course is 1 week or as recommended by a doctor. If you need a longer use, you should first consult with a specialist.
It is recommended to take the tablets in short courses. This will reduce the risks of adverse reactions. The drug has numerous contraindications for admission, including pregnancy and lactation. Therefore, it is recommended that you familiarize yourself with them in advance. Age restrictions - for patients over 18 years old. Terms of sale - prescription. The price of a medicine in public and private pharmacies in Russia is 130-380 rubles.
Aertal
Aceclofenac (100 mg) - tablets, the price of which may differ significantly from the price of similar drugs. At the same time, the cost of generics can be either higher or lower. This substitute is available in Spain in the form of oral tablets. The active ingredient is aceclofenac. The drug belongs to the group of non-steroidal anti-inflammatory drugs and is prescribed for pain and inflammation of the articular system.
Recommendations:
- arthritis;
- spondylitis;
- pain in the teeth;
- headaches;
- dysmenorrhea.
Dosing rules: 1 capsule 2 times a day (preferably in the morning and evening). Can be consumed with meals. The maximum daily dosage is 0.2 g.
The duration of the course without consulting a doctor is no more than 1 week. If you need a longer use, you must first consult with a specialist.
The drug has multiple contraindications, therefore, before taking it, you need to familiarize yourself with them in advance. In this case, you should consult your doctor. However, it is recommended to take the medicine in short courses, which will reduce the risks of developing side effects. The medicine is prohibited for use during pregnancy and breastfeeding. Age restrictions - for patients over 18 years old. Dispensing conditions - prescription. The cost of the drug in regional and regional pharmacies in Russia varies between 340-400 rubles.
Asinak
This generic is produced in India as an oral tablet. The active ingredient is aceclofenac. The agent is a representative of a non-steroidal anti-inflammatory group of drugs and is used for various disorders of the musculoskeletal system, which are accompanied by pain.
Indications:
- osteoarthritis;
- spondylitis;
- rheumatoid arthritis;
- gout;
- lumbago;
- periartitis affecting the shoulder and shoulder joints;
- rheumatism of soft tissues.
Dosing regimen: 100 mg (1 capsule) 2 times a day - in the morning and in the evening. The duration of treatment is no more than 1 week. If you need a longer intake of funds, you should first consult with a specialist. The medicine has numerous contraindications, which should be consulted in advance. Age restrictions - for patients over 18 years old. The medicine is prohibited for use during pregnancy and breastfeeding. The way of implementation is prescription. The cost of a medicine in commercial and state pharmacies in Russia starts from 130 rubles.
Terms, conditions of sale and storage
- The drug should be stored in a dark and dry place at temperatures up to 25 0C.
- Shelf life is 3 years from the date of issue.
- Do not use after the expiration date stated on the package.
- Dispensing method - prescription.
Price
Drug prices may vary slightly depending on the region and area of sale.
Region / region | Dosage form / dosage | Price |
Moscow, Moscow region | Tablets, 100 mg | RUB 230-430 |
St. Petersburg | Tablets, 100 mg | RUB 260-450 |
Saint Petersburg (suburbs) | Tablets, 100 mg | RUB 280-400 |
Leningrad region | Tablets, 100 mg | RUB 320-390 |
Novgorod region | Tablets, 100 mg | RUB 300-395 |
Before using Aceclofenac (100 mg), you should consult with a specialist and carefully study the instructions for using the tablets. You can find out the exact cost and purchase a medicine at any commercial or state pharmacy located in your place of residence.
Video about the active substance Aceclofenac
Instructions for using Aertal: