Ipidacrine tabl 20 mg. Price, instruction

Ipidacrine is the active ingredient in the preparations used to normalize the transmission of nerve impulses. Medicines are produced in the form of a solution for injection and tablets, but tabletki 20 mg is more popular. This form is more convenient to use and dispense. Since the component is expensive, the price of the product with its composition is high.

Composition and form of release

On the basis of ipidacrine, preparations can be purchased in the form of a solution for injection (for subcutaneous and intramuscular administration), as well as in the form of tablets (for oral administration). Depending on the manufacturer, the composition of the auxiliary elements changes, as well as the appearance of the medicines.

Pharmacological properties

Medicines with ipidacrine in the composition belong to the group of agents that restore the transmission of a nerve impulse.

Pharmacodynamics and pharmacokinetics

Ipidacrine tabl 20 mg, the price of which depends on the place of purchase, has an effect on a cholinesterase inhibitor. The substance is responsible for improving the conduction of nerve impulses in the neuromuscular and central nervous system. Changes in impulse transmission are noted due to blocking of potassium channels.

In addition to normalizing the transmission of nerve impulses, ipidacrine has the following effects on the body:

• activates memory;
• improves memorization of new information;
• slows down the development of dementia in dementia;
• activates the contraction of smooth muscles (can cause the development of bronchospasm);
• increases the amount of saliva production;
• enhances the contraction of the uterus (during pregnancy, it is dangerous to miscarry, and during menstruation, profuse bleeding);
• activates the tone and motility of the digestive tract and bladder;
• constricts the pupils, and also reduces their sensitivity to external changes (may be manifested by "fading" of the gaze ");
• improves mood;
• increases the likelihood of developing allergies, due to an increase in the susceptibility of cells to histamine;
• reduces the number of heartbeats.

After ipidacrine is introduced into the body (oral or injection), it is easily and quickly absorbed. The effect of the substance is noted approximately 1 hour after taking the pills, and 1/2 hour after the injection. After application, about 50% of ipidacrine binds to the plasma protein, due to which the drug enters all organs and tissues of the body within about 40 minutes.

The substance is excreted both in the urine and in the feces approximately 2-3 hours after using the drug. Ipidacrine has no effect on vascular tone.

Indications for use

Doctors prescribe medications with ipidacrine for the following deviations:

• neuropathy. Pathology is expressed by a violation of the state and functioning of one or more nerves of the peripheral system;
• neuritis. Deterioration in the activity of the nervous system, due to the development of inflammatory processes in them. Is accompanied by severe pain;
• polyneuritis. Numerous damage to nerve cells, develops more often after a toxic damage to the body or a severe infectious disease;
• myelopolyradiculoneuritis, manifested by the development of an inflammatory process in the spinal cord;
• myasthenia gravis. Pathologically fast muscle fatigue;
• dementia (dementia). It is manifested by a decrease in memory and forgetting of acquired knowledge;
• multiple sclerosis. Disruption of the activity of nerve cells in the brain and spinal cord;
• bulbar paralysis. Lesion near the lingual and hypoglossal nerves;
• damage to the central nervous system, which are accompanied by impaired motor functions. Preparations with ipidacrine are used in complex therapy;
• memory impairment;
• decreased concentration of attention;
• emotional instability;
• violation of clarity and clarity of thoughts;
• Alzheimer's disease. It is manifested by a decrease in intelligence, memory and personality changes;
• encephalopathy. Pathology is expressed by a deterioration in the activity of nerve cells in the brain, as a result of metabolic disorders;
• deterioration of cerebral circulation;
• recovery period after traumatic brain injury;
• cerebral dysfunction. It manifests itself in children with learning disabilities, speech and inappropriate behavior, due to insufficient activity of the central nervous system;
• low labor activity;
• deterioration of the contractile activity of the intestines, leading to the development of constipation;
• poisoning of the body with toxins or potent medications, accompanied by a deterioration in the functioning of the nervous system.

It is strictly forbidden to use drugs with ipidacrine without a doctor's prescription, even with the aim of increasing memory and attention.

Contraindications

Ipidacrine tabl 20 mg (the price of drugs with this substance depends on the manufacturer) should not be used if the patient has the following prohibitions:

• increased susceptibility to the composition of medicines;
• epilepsy;
• diseases accompanied by seizures;
• regular pain in the heart area;
• severe heart disease;
• kidney or liver disease;
• an underestimated number of heartbeats;
• violation of gait;
• period of bearing the child;
• intestinal obstruction;
• deterioration of urine output due to diseases of the urinary system
• bronchial asthma, even in a mild form;
• the patient has infectious pathologies affecting the respiratory system;
• the patient's age is up to 18 years.

During lactation, the drug is also not used, since ipidacrine passes into breast milk and may harm the baby.

In the presence of peptic ulcer disease in the gastrointestinal tract, increased production of thyroid hormones and diseases of the cardiovascular system, you can use medicines with ipidacrine only under medical supervision.

Method of administration and dosage

Medicines in tablet form containing ipidacrine in an amount of 20 mg should be used taking into account the type and severity of the disease, as well as the general condition of the patient. The dosage of medicines in most cases is selected individually by the doctor.

In cases where there are no restrictions on taking the drug, then it is allowed to use the drugs according to the classical scheme according to the type of disease.

Rules for dosing and using medicines with ipidacrine at a dosage of 20 mg:

Type of disease	Single and daily dosage	Well
Neuropathy	Take 1 tablet every 8 hours.	Use drugs until the pathology is eliminated, but not more than 12 months.
Neuritis, polyneuritis, myelopolyradiculoneuritis	Prescribe 1-2 tablets 3-5 times every 24 hours.	Apply funds for 6-8 months.
Myasthenia gravis, impaired motor functions	Use 1-2 tablets 5 to 6 times during the day. The daily dosage should not exceed 10 tablets.	The course can last from 1 to 2 months. Repeat the course in 30-60 days, with the permission of the doctor.
Myasthenic crisis	Take ¼ or ¾ tablets 1-2 times in 24 hours.	Medicines are used for up to 3 months.
Dementia, multiple sclerosis, bulbar palsy	Take 2 tablets, 4 to 5 tablets per day.	The course is from 4 to 6 months. Extension up to a year is possible.
Poor memory, decreased concentration, emotional instability	Prescribe 0.5 tablets 1-2 times a day. A single dosage can be increased to a whole tablet.	The duration of treatment can be from 1 to 3 months. Longer therapy is possible with the permission of the doctor.
Alzheimer's disease	A single dosage is selected individually, while the daily dose should not exceed 200 mg.	Take medication for up to 12 months. Next, a break is required, the duration of which is determined by the doctor.
Encephalopathy, TBI, deterioration of blood circulation in the brain	Use 1-2 tablets 3-4 times in 24 hours, it is allowed to increase up to 6 times.	The duration of the course is set individually by the attending physician.
Poor labor	Take 1 tablet every hour, no more than 3 tablets.	—
Disruption of bowel function	Take ¾-1 tablets 2 to 3 times a day.	Use funds from 7 to 14 days.
Poisoning the body with toxins or "heavy" medicines	Prescribe 1-2 tablets from 3 to 6 times every 24 hours. But no more than 10 tablets per day.	The course of treatment is determined by the doctor according to the dynamics of therapy.

Repetition of the prescribed courses is possible after consultation with the attending specialist. And also in severe forms of illness, the doctor can increase both a single and daily dosage. In this case, the patient must be constantly under the supervision of a doctor.

Side effects

Ipidacrine tabl 20 mg should be taken strictly according to the instructions, with indications and no contraindications. In addition, a consultation with a treating specialist is required to get acquainted with the peculiarities of the reception, as well as the average price per package of the product.

The use of drugs with this substance may have the following side effects:

• decreased appetite, accompanied by a decrease in body weight;
• increased production of saliva;
• nausea after taking the pill;
• vomit. The negative reaction is more severe immediately after using the medication;
• increased stool frequency due to increased peristalsis in the intestines;
• yellowness of the skin and white of the eyes, due to an increase in the amount of bilirubin. Pathology develops as a result of impaired liver activity;
• severe dizziness;
• stomach ache;
• inconsistent muscle contraction;
• allergy in the form of itching, swelling of the respiratory tract, rash;
• development of severe bronchospasm;
• increased sweating;
• decrease in body temperature;
• increased sleepiness;
• convulsions and tremors of the limbs;
• constriction of the pupil, as a result, vision deteriorates;
• feeling of heartbeat;
• increased production of mucus in the bronchi;
• chest pain;
• exacerbation of diseases of the digestive tract;
• violation of urination and kidney function;
• increased cough in infectious diseases of the pulmonary system;
• miscarriage, when using drugs during pregnancy or severe uterine bleeding, when using drugs during menstruation;
• decrease in the number of heartbeats.

During the tests, it was recorded that the likelihood of developing side effects from the use of drugs with ipidacrine is no more than 7%. Moreover, the abolition of the drug in use is not required for all side effects.

Overdose

When using drugs with ipidacrine, it is important to strictly observe the single and daily dosage, as well as adhere to the specified course.

In cases of exceeding a single dosage, or with a very long course, patients have the following signs of an overdose:

• severe bronchospasm leading to the development of severe suffocation;
• uncontrolled movements of the pupils;
• profuse vomiting;
• lack of appetite;
• increased salivation and lacrimation;
• increased sweating;
• fecal incontinence;
• severe gait disturbance;
• involuntary urination;
• a sharp decrease in heart rate;
• pronounced violation of the rhythm of heart contractions;
• lowering the blood pressure indicator;
• causeless anxiety, fear and excitement;
• severe weakness;
• severe abdominal pain;
• severe cramps;
• deterioration in speech;
• a rapid drop in body temperature;
• severe impairment of the activity of the kidneys, heart and liver;
• in severe cases, a coma may develop.

With the development of poisoning with drugs containing ipidacrine, gastric lavage with the intake of sorbents is necessary. Further, symptomatic therapy is performed. Anticholinergics (Atropine, Cyclodol) can also be prescribed.

special instructions

Ipidacrine tabl 20 mg, the price of which is discussed below, is recommended for use in compliance with the following nuances:

• taking ipidacrine tablets may cause vomiting. If vomiting occurs immediately after using the drug, then you do not need to repeat taking the pill, it must be taken at the next time according to the instructions;
• to increase the number of heart contractions and reduce salivation, you can take Atropine or Metacin;
• if it is necessary to drive vehicles and perform hazardous work, special care should be taken;
• if the patient has chronic diseases (especially in the acute stage), drugs with ipidacrine can be used only after the permission of the doctor.

It is strictly forbidden to consume alcohol and alcohol-containing medicines during the course of the course.

Drug interactions

Medicines with ipidacrine cannot be combined with the following drugs:

• reduces the effect of local anesthetics and antibiotics;
• increases the sedative effect of sleeping pills;
• beta-blockers increase the severity of bradycardia;
• Atropine, Metacin and Cyclodol reduce the severity of side effects;
• together with alcohol-containing medicines increases the load on the liver.

Simultaneous administration of medicines with ipidacrine with analogues can lead to suffocation and cardiac arrest.

Analogues and prices

Ipidacrine tabl 20 mg (the price of the product is quite high) is contained in the following medicines (in addition, analogs are presented in the table):

List of drugs with ipidacrine and analogues	Release form	Features of the drug	Prices in rubles.
Ubretid	Solution for injection and tablets, with the active ingredient distigmine bromide.	The drug has a long-term effect from 8 hours to 2 days. Other characteristics are similar to the original.	Average price 4000 rubles. You need a prescription to buy.
Proserin	It is produced in the form of a solution for injection with the active ingredient proserin. The package contains 10 ampoules.	The remedy begins to act in 30 minutes and retains the healing effect for up to 24 hours. The rest of the data is identical to the original.	The average cost is about 100 rubles. Prescription drug.
Kalimin 60N	Produced in the form of tablets with the main component pyridostigmania bromide. The package contains 100 tablets.	The main component does not bind to plasma proteins; therefore, the drug has low bioavailability. The therapeutic effect lasts about 3 hours.	The average price is about 700 rubles. a prescription is required to purchase.
Neuromidine	Produced in the form of a solution for injection and tablets with the active ingredient ipidacrine.	The main characteristics of the drug are similar to those described in this publication.	The average cost is 1200 rubles. prescription medication.
Amiridin	Tablets with the active ingredient ipidacrine. Number of tablets, 10 and 50 pcs. packaged.	The drug is currently not released due to the lack of extension of the review.	No price specified. Prescription agent.
Neuromidine	Solution and tablets with the main component ipidacrine.	All characteristics of the drug are similar to those discussed in the article.	The approximate cost is 1200. Dispensed by prescription.
Axamon	Tablets based on ipidacrine. The package contains 50 pcs.	The description of the medication is identical to that presented in this material.	The approximate price is 1200 rubles. Prescription remedy.
Ipigrix	A solution with the main component ipidacrine.	Instructions for the drug are similar to those presented in the publication.	The approximate cost is 1400 rubles. available by prescription.

The choice of drugs with ipidacrine or analogs is made by the doctor. Analogues are used only if the patient has an intolerance to the main component.

Terms of sale, storage

You can buy drugs with ipidacrine only with a prescription from a doctor. The shelf life of medications depends on the additional composition. It should be borne in mind that drugs can cause serious harm to the body if poisoned, so they should be kept away from children.

Ipidacrine tabl 20 mg is popular among patients due to its high efficacy and low likelihood of side effects. Additionally, the product is convenient to dose and take on the road. If the patient has severe gastrointestinal pathologies, then the medication is prescribed in the form of a solution for injection. The disadvantage of drugs, and their analogues, is the high price.

Author: Kotlyachkova Svetlana

Video about the drug Ipidacrine

Ipigrix 20 mg: