Opatanol (Opatanol) eye drops. Price, instructions for use, analogues, reviews

Opatanol are affordable eye drops that are widely used for elimination of symptoms of an allergic reaction. The drug has a pronounced antihistamine effect on the mucous tissues of the eyes and eyelids. Conducted clinical studies have not revealed any dangerous consequences of their use for human health.

Form of release and composition of the drug Opatanol

Opatanol eye drops are sold in convenient 5 ml medical plastic bottles. For extra safety, they are equipped with a standard tamper-evident ring. The price of drops is made up of many factors, including the safe composition of the drug.

The active ingredient is olopatadin. The concentration is strictly standardized and is at around 0.1%, which corresponds to 1.11 mg of olopatadine hydrochloride. The content of a verified amount ensures high efficiency and minimizes the likelihood of undesirable side effects.

Auxiliary components:

• disodium phosphate dodecadecate;
• benzalkonium chloride;
• sodium chloride;
• HCl or NaOH;
• pure water.

Acid or alkali is added to the solution to achieve and consistently maintain the required ph level.

Pharmacological properties

Olopatadine blocks or reduces the sensitivity of receptors to the action of histamine. The last substance is an organic compound - a biogenic amine, which provokes the development of immediate allergic reactions. In addition, it belongs to the regulators of other physiological processes in the human body.

Pharmacodynamics and pharmacokinetics

Histamine is formed by decarboxylation of the amino acid histidine, the production of which depends on histidine decarboxylase. The produced substance is concentrated in mast cells and basophils together with heparin.

Histamine that has not undergone biochemical transformation is quickly neutralized by oxidation by histaminase. The end products of this process are imidazolylacetic acid and N-methylhistamine, which are eliminated from the body through renal filtration of the blood.

Indications for use

Opatanol - eye drops, the price of which will be fully justified by the achieved effect.

They are recommended for correcting the following conditions:

• allergic conjunctivitis;
• pollinous conjunctivitis;
• allergic dermatitis;
• keratoconjunctivitis;
• allergy to cold.

With allergic conjunctivitis and dermatitis, the provocateur of the onset of unpleasant symptoms often becomes the use of medications for the treatment of eye diseases and the use of insufficient quality cosmetics. Common symptoms include redness of the mucous membranes, severe swelling of the eyelids, small rashes, and increased tear production.

Pollinous conjunctivitis is the result of the influence of pollen from shrubs and trees during the period of active flowering. This form of chronic disease is characterized by seasonal activity. Therefore, with an already recorded tendency to develop allergies, prophylactic instillation of drugs against the possible appearance of acute symptoms is recommended.

Keratoconjunctivitis, or vernal catarrh, is also a seasonal illness. But in this case, the reason is the increase in air temperature outside, combined with the effects of solar cure, ultraviolet radiation.

In addition, aromas released by flowering plants are also a risk factor. Men are at greater risk. Signs of pathology - the appearance of small papillae on the conjunctiva or in the extreme zone of the cornea in combination with lacrimation, itching, burning of the skin and eyeballs.

Cold allergy refers to pseudological conditions in which a reaction occurs in response to exposure to low air temperatures. There are no immunological changes. Pathology is associated with disturbances in the exchange of histamine and its perception by cells.

Contraindications

Opatanol - eye drops, the price of which is relatively low. They should not be used in case of identified intolerance to the active or auxiliary components. For the treatment of allergies, it is recommended to consult an ophthalmologist to choose a milder drug or to focus on a systemic approach to therapy to suppress symptoms.

At what age can eye drops be used?

There is no sufficient experience in using the product in babies under 3 years old. Therefore, the drug is recommended for the treatment of children over 3 years old in the same dosages and frequency as for other patients.

Instructions for use, dosage

Drops should be instilled into the conjunctiva, slightly pulling the lower eyelid. In this case, the access will become more extensive, and the drug will be evenly distributed over the entire area of ​​the lesion.

Dosage:

• 1 drop in each bag of conjunctiva;
• instillation mode - 2 times a day.

It is recommended to shake the bottle thoroughly before use to evenly distribute the constituent components. The duration of the course of treatment can be up to 4 months of continuous use of drops.

Detailed instructions for instilling the drug in the eyes:

1. it is not recommended to use makeup during the treatment period, otherwise it is advisable to remove all makeup with a mild agent, not allowing it to get into the eyes;
2. before performing the procedure, be sure to wash your hands with warm water and antibacterial soap;
3. in the case of wearing contact lenses, it is recommended to remove them, you can put them on again half an hour after using the drug;
4. it is necessary to dose the medicinal solution, throwing your head back and opening your eyes wide, preferably lying in bed;
5. the bottle should be turned upside down, without squeezing its lateral parts and without touching the nose to the surface of the mucous membrane of the eye;
6. after that, you need to pull back the lower eyelid, while the patient must bring the pupils up;
7. you need to dose the solution carefully, gently squeezing the bottle with the product;
8. after separating the drop and getting it into the space behind the eyelid, you need to close the eye and gently massage its inner corner for 2-3 minutes;
9. at the same time, it is recommended to rotate the eye in all directions.

After the completion of the procedure, if the secretion of tear fluid has begun, it should be blotted with a clean napkin, avoiding reuse. The drug must be tightly closed immediately after instillation and sent for further storage.

Side effects

Opatanol - eye drops, the price of which is justified by their effectiveness. But they can cause side effects.

Among undesirable actions, local reactions are rare, but local reactions occur:

• lacrimal fluid formation;
• redness of the conjunctiva;
• feeling of a foreign body;
• blurred vision;
• burning pain in the eyes;
• swelling of the eyelids;
• keratitis;
• iritis.

In addition to local, systemic reactions may develop with a frequency of up to 1% among the total number of patients:

• violations of the vestibular apparatus;
• changes in taste perception;
• exacerbation of nasal pathologies;
• pain in the head.

If any of the symptoms listed above appears, it is recommended to consult an observing specialist.

Overdose

When applied topically, overdose is unlikely.

special instructions

Due to the possibility of a short-term deterioration in vision immediately after using the drug, it is forbidden to start working with moving mechanisms immediately after the installation of the solution. In chronic dry eye syndrome, therapy cannot be continued for a long period of time.

It is recommended to put on contact lenses after instillation at least 25-30 minutes after using the drug. In case of any damage to the corneal layer, the possibility of further treatment should be discussed with an ophthalmologist.

Drug interactions

When combining several drugs, a time interval of at least 5-8 minutes should be maintained. Opatanol enhances the pharmaceutical activity of drugs from the group of corticosteroid hormones.

Storage conditions, shelf life and dispensing from pharmacies

The expiration date affects the effectiveness of the medication. It is unacceptable to use an expired drug.

Storage conditions and periods:

• minimum shelf life, subject to tightness - 3 years from the date of production;
• after the first opening, the drug is approved for use for no more than 1 month;
• the ambient temperature should not exceed 30 ° С;
• freezing the solution can lead to the loss of its medicinal properties;
• the drug should be stored in an area closed for children.

After the end of the period indicated on the bottle, the solution must be disposed of with household waste.

Analogs

Opatanol - eye drops, the price of which may differ in different pharmacies. In addition to the described remedy, you can use other effective drugs. The need for replacement sometimes arises in the absence of drops in pharmacies or in case of intolerance of various degrees of severity.

Visin Allergy

The drug helps to quickly relieve redness, itching and swelling of tissues in the eye area.

As an active ingredient, the preparation contains:

• levocabastine hydrochloride - 0.54 mg / ml;
• in terms of levocabastine - 0.5 mg / ml.

The standard concentration is 0.05%.

Among the excipients are propylene glycol, sodium hydrogen phosphate monohydrate, hypromelose, polysorbate 80, benzalkonium Cl, edetate Na, purified water in the amounts required to stabilize the active ingredient and achieve optimal rheological properties solution.

Levocabastine is a long-acting selective histamine receptor blocker. The initial effect occurs already 5 minutes after application. The result is the elimination of itching, hyperemia, edema of the conjunctival sac, the cessation of tear production.

Application and dosage:

• the solution is applied topically 1 drop 2 times a day;
• with severe symptoms, it is allowed to use the remedy up to 4 times a day.

These recommendations are for adults and children over 12 years of age. The duration of treatment depends on the initial intensity of the symptoms, so the total duration of the course of therapy should be determined by the effect achieved. With the disappearance of all manifestations of allergies, treatment can be stopped without any special action. Withdrawal syndrome was not observed when using the drug.

During the treatment, you should follow the rules of hygiene and, in addition to cleaning the hands and eyes, do not touch the tip of the bottle and, after completing the next procedure, carefully screw the cap.

Allergodil

The drug contains azelastine g / x - 500 mcg in 1 ml. 1 package includes a 6 ml drug vial complete with medical instructions. For the most convenient dosing of the drug, the bottle is equipped with a drip tip.

Additional components:

• hydroxypropyl methylcellulose;
• disodium edetate;
• benzalkonium Cl;
• sorbitol 70%;
• Na hydroxide;
• purified water.

The medicinal solution produces an intense and long-term therapeutic effect in the development of any forms of allergic reactions. Additional effects include the removal of inflammation and the stabilization of membrane septa in cells.

Azelastine has the ability to stop the production and free release of mediators of the initial and late-stage manifestations of allergies, including leukotriene, histamine, platelet activating factor and serotonin. Additionally, the active substance reduces the number of cells at the level of molecular attachment and eosinophils.

On the part of the pharmacokinetic features of the active substance molecule, the use of azelastine in the form of eye drops the levels of reaching the highest level in the body were extremely low and were below the possibility detection.

Recommendations for medical use:

• with seasonal conjunctivitis by the type of allergy, patients aged 4 years and older should use 1 drop of the solution in both eyes 2 times a day with the same interval of time;
• non-seasonal conjunctivitis - adults and children from 12 years old are recommended to use the drug 1 drop in both eyes up to 2 times a day with a 12-hour interval;
• in the case of a strong severity of painful symptoms, the frequency can be increased up to 4 times a day.

In the presence of contact with allergic agents, prophylaxis is recommended - the use of a solution with a lesser, but without specific indications, frequency.

Dexamethasone

The drug is one of the most effective medicines for allergies. As an active ingredient, the solution for instillation into the eyes contains dexamethasone sodium phosphate in an amount of 1 mg per 1 ml.

Pharmachologic effect:

• dexamethasone has a quick and pronounced effect against inflammation and allergic reactions;
• the substance suppresses the production and release of inflammatory mediators by eosinophils;
• inhibits the migration of mast cells and reduces the permeability of the capillary walls.

When applied topically, dexamethasone quickly and almost completely penetrates the cornea and the adjacent conjunctiva. In liquids, the substance reaches therapeutic concentrations and immediately begins to block the activity of the produced histamines.

Recommendations for medical use:

• in case of acute inflammation or allergic reaction, the drug should be used 1 drop every 1-2 hours;
• after the onset of improvement in the condition of the eyes, the frequency should be reduced to 1 drop every 4-6 hours;
• the maximum duration of treatment is no more than 14 days.

In some cases, it is possible to extend it up to 5 weeks, taking into account the clinical picture, causes and effects of less active drugs.

Terms, conditions of sale and storage

Opatanol - eye drops, the price and effectiveness of which will be commensurate if the recommended storage parameters are observed. When buying a drug, you do not need to present a prescription from a doctor.

Price in pharmacies in Moscow, St. Petersburg, regions

The average cost of a medicine in most online pharmacies is about 460 rubles. In ordinary pharmacy points, the price can vary within a fairly wide range.

Opatanol is a good and affordable remedy for eliminating allergic reactions on the most sensitive organ in humans. Eye drops not only do a good job in case of developed symptoms, but also prevent any manifestations in case of accidental contact with an allergen.

Their mild action, effectiveness, combined with a reasonable price, brought them to the level of the most popular drugs with a similar action.

Article design: Vladimir the Great

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