Bronchobos (Bronchobos) syrup for children. Instructions for use, analogues, composition, price, reviews

Treatment of cough with syrup for children Bronchobos should be started at the first symptoms of the disease. This remedy is an effective medication with expectorant and mucolytic action. The advantage of the suspension is the minimum of side effects and the possibility of using it in patients of different ages.

Forms of release and composition of the drug

The cough medicine is manufactured by Bosnalek, a Bosnian pharmaceutical company. Suspension is not the only form of drug release: gelatin capsules have the same composition and principle of action.

The syrup has a pleasant raspberry aroma, sweetish aftertaste, viscous consistency and pink tint. The release form Bronchobos contributes to the psychologically comfortable treatment of cough in preschool children.

The suspension is presented on the pharmaceutical market in dosages of 2.5% and 5%. The drug is packaged in 200 ml dark glass bottles equipped with a special lid with a protective function. For easy and simple dispensing, in the carton, in addition to the bottle with the drug and instructions, there is a 5 ml measuring spoon.

The active ingredient in Bronchobos is carbocisteine, a mucolytic that reduces the viscosity and increases the elasticity of sputum in the respiratory tract. 5 ml of medication with a dosage of 2.5% contains 125 mg of carbocisteine, respectively, in 5 ml of suspension - 250 mg.

In addition to the main active ingredient, the syrup contains:

• purified water;
• glycerol;
• glycerol;
• citrates;
• flavors;
• food colorings;
• saccharinates.

In addition, ethanol is present in Bronchobos baby syrup. This is important to consider before starting treatment. No ethyl alcohol is added during capsule production.

Pharmacological properties

Cough suspension Bronchobos is one of the popular mucolytic and expectorant drugs. The therapeutic effect of the drug is achieved through the activation of sialic transferase, an enzyme present in the structure of the goblet cells of the mucous membranes of the upper respiratory tract.

Due to the systematic flow of carbocisteine ​​into the bloodstream, the level of acidic and neutral particles of mucous secretion produced by the trachea, bronchi, maxillary sinuses is restored.

The phlegm formed by the bronchi and nasal cavity becomes less viscous, as a result of which the discharge is easier to cough up, the patient's condition is stabilized. The course of syrup treatment accelerates the healing process of the mucous membrane of the respiratory tract and nasal cavity, restores the texture of the ciliated epithelium.

In addition to the above, Bronchobos triggers the production of lgA immunoglobulins, which are responsible for the performance of local immunity.

Pharmacodynamics and pharmacokinetics

Due to the activation of sialic transferase when using the drug, the enzymatic activity of bronchial cells is normalized, the susceptibility of cough receptors decreases.

Despite the high rate of absorption of the active component, its bioavailability is below average - when used orally, less than 10 of the total amount of carbocisteine ​​consumed is delivered to the respiratory organs %.

The maximum concentration of this component in the blood serum and epithelial mucosa is noted 1.5-2 hours after ingestion of the syrup. It takes twice as long for carbocisteine ​​from capsules to enter the bloodstream. Regardless of the form of the drug used, it remains in the body for the next 8 hours.

Bronchobos is a syrup for children that goes through a metabolic cycle in the liver. The active substance also reaches the tissues of the middle ear. When using the drug in the maximum allowable dosage, carbocisteine ​​accumulates in the bronchial secretions.

Active compounds leave the body through the excretory system along with urine (up to 90% of the substances remain in their original form, 10% are excreted as metabolites). After 2 hours after taking the syrup, carbocisteine ​​enters the kidneys, and 3 days after the last use of Bronchobos, excretion ends.

Indications for use

Bronchobosom can be treated for both adults and children. The use of the medication is allowed from the age of 3. Before using the drug, it is important to consult a doctor and make sure there are no contraindications.

Cough syrup with carbocisteine ​​is prescribed for diseases such as:

• bronchitis, including a chronic disease;
• otitis media of the middle and outer ear;
• bronchial asthma;
• tracheitis;
• sinusitis;
• rhinitis, including allergic.

It is possible to use Bronchobos syrup for other pathologies of the respiratory system, accompanied by the formation of a thick secretion that is difficult to separate. In infectious and inflammatory respiratory diseases, syrup can be prescribed as a symptomatic agent.

In some cases, the drug is recommended to be taken not for therapeutic purposes, but as an auxiliary funds in preparation for the diagnostic procedures of the respiratory organs (bronchoscopy, radiography).

Contraindications

Children's suspension Bronchobos does not belong to the category of hazardous drugs with toxic components. According to reviews, the syrup is tolerated without complications at any age. But this drug has strict restrictions on its use due to the presence of carbocisteine ​​in its composition.

Also, you can not use Bronchobos syrup with individual intolerance to the main or auxiliary substances. If the patient has previously experienced a negative reaction to other drugs with carbocisteine, the suspension should not be used.

In addition to an allergic reaction to the drug, relative contraindications to the use of Bronchobos are:

• urinary tract infections;
• chronic kidney disease (glomerulonephritis, pyelonephritis);
• period of exacerbation of gastric ulcer or 12 duodenal ulcer.

An absolute ban on the use of Bronchobos in any dosage occurs with hepatosis, liver fibrosis, neurological disorders accompanied by epileptic seizures, as well as with craniocerebral injuries.

In the annotation to Bronchobos syrup, it is recommended not to use the drug during pregnancy (especially in the first trimester) and lactation. With regard to capsules, the manufacturer is less categorical: if the expected benefit for the woman prevails over the potential risk to the fetus, the medication can be taken in the II and III trimesters.

At what age can the drug be used?

Carbocysteine ​​medications cannot be used to treat coughs in children under 3 years of age. This prohibition is directly related to the anatomical inability of children at an early age to fully cough up their throat, and mucolytic and expectorant syrups can cause impaired respiratory function.

Bronchobos in capsules and 5% syrup is contraindicated in patients under 15 years of age. A suspension with a dosage of 2.5% carbocisteine ​​can be given to children from 3 years of age.

Instructions for use, dosage

Bronchobos is a syrup for children, which is important to take strictly according to the instructions. For patients under 15 years of age, doctors prescribe a 2.5% concentration of the suspension.

At the same time, there is no universal dosage of the drug and the frequency of daily intake: the treatment regimen for a disease accompanied by a cough is established by the attending physician in private. The dosage depends largely on the severity of the disease and the age of the patient.

Concentration of carbocisteine	Child's age	Single dose	Daily dose	Maximum number of appointments, day
2,5 %	3-6 years old	5 ml	10-20 ml	2-4
2,5 %	6-15 years old	5-10 ml	20-30 ml	2-4
5 %	Adults and adolescents over 15 years old	15 ml	45 ml	3

Thus, the maximum daily dose for a child is 20-30 ml of syrup. For cough, which is a symptom of acute respiratory infections, a minimum amount of the drug is usually prescribed. For more complex diseases (for example, with acute bronchitis or tracheitis), the doctor may decide to prescribe the maximum possible dose, taking into account the patient's condition and the severity of the symptoms.

Adolescents and adult patients have to take 3 scoops of syrup 3 times a day. This form of therapy brings a lot of inconvenience, therefore capsules are a simpler form of treatment at this age. The duration of treatment is on average 1-1.5 weeks.

Side effects

Syrup for children Bronchobos rarely provokes negative reactions of the body. Side effects most often occur due to a violation of the recommended dosage regimen of the medication or its unsystematic use. The reason for the appearance of specific symptoms against the background of treatment with Bronchobos can also be an individual intolerance to any of the components in the composition of the drug.

Among the studied adverse reactions to this syrup, it is worth noting:

• disorders of the immune system in the form of urticaria, itching, skin rashes, allergic vasculitis (in isolated cases, patients developed an anaphylactic reaction);
• deterioration in the performance of the thyroid gland and other elements of the endocrine system, manifested by a change in hormonal levels, hypoglycemia;
• hemolytic anemia, inhibition of hematopoietic function, leukopenia;
• dyspeptic disorders (periodic nausea, changes in stool, pain in the epigastric region, bile stasis, medicinal jaundice);
• temporary impairment of visual acuity;
• rapid fatigue, frequent headaches, muscle paresis, weakness, numbness of the extremities;
• lowering blood pressure.

Bronchobos syrup is suitable for the treatment of bronchial asthma in children. However, with this disease, the medication must be used with extreme caution, since carbocisteine ​​in high doses can provoke airway obstruction.

Side effects may not develop immediately, but as the active substance accumulates in the body. In this regard, for patients whose professional activities require increased concentration of attention and speed of reaction, it is better to replace Bronchobos with an analogue.

Overdose

Even a slight excess of the syrup dosage is accompanied by characteristic signs in children.

Most often, the following symptoms occur:

• nausea;
• diarrhea;
• stomach ache.

There is no specific antidote to carbocisteine. In case of an overdose, the patient is prescribed gastric lavage, the intake of adsorbents and bed rest.

special instructions

Additional recommendations for taking the drug Bronchobos are presented in the annotation for patients with gastric ulcer. The syrup is not prohibited for use, subject to mandatory dosage adjustment.

The daily volume of the suspension should be kept to a minimum. If the prescribed amount of the drug is not enough for positive dynamics, it is recommended to combine taking the syrup with physiotherapy methods of treatment. Complex therapy should be supervised by specialists.

The effect of the active components of the syrup on psychomotor activity has not yet been fully studied, therefore, during the period of treatment, it is advisable to refrain from controlling complex mechanisms.

In addition, the presence of ethyl alcohol in the composition of this drug automatically entails the inability to drive a car during treatment. 1 scoop of syrup contains 125 mg of ethanol. This fact should be taken into account when planning trips and important matters.

Drug interactions

Bronchobos is a syrup for children that cannot be combined with all medicines, without exception. It should be borne in mind that the combination of carbocisteine ​​with hormonal agents leads to a mutual enhancement of the action of the drugs.

When using syrup together with Theophylline, which is usually prescribed for the treatment of obstructive pulmonary diseases, the likelihood of an increase in the activity of a bronchodilator must be taken into account. Atropine-containing medicines, on the contrary, inhibit the action of Bronchobos.

Another important nuance is the presence of ethyl alcohol.

This component in the cough syrup makes it impossible to concurrently take other medicines belonging to the groups:

• antibacterial;
• antineoplastic (cytostatic);
• antimycotic;
• antidiabetic;
• antiallergic;
• antipsychotics;
• tranquilizers;
• analgesics;
• antipyretic;
• anticonvulsants.

The use of these types of drugs together with alcohol is not allowed.

Analogs

Bronchobos is a syrup for children that can be replaced with medicines that have:

• similar composition;
• the same form of release;
• a similar principle of action.

The most popular analogues of a cough suspension, which are also available in a pharmacy without a prescription, are considered to be Fluifort, Libeksin Muko and Fluiditek.

Fluifort

This is a drug from an Italian manufacturer with an identical set of active ingredients. This product has 2 forms of release - suspensions and granules for syrup preparation. Unlike Bronchobos, Fluicort can be given to children over 12 months of age.

The syrup is also contraindicated in women in early pregnancy. The possibility of treatment with Fluicort in the II and III trimesters is not excluded, however, in this case, the drug should be used with extreme caution. During the period of therapy, lactation will also have to be interrupted. The price of the medicine is in the range of 375-497 rubles.

Libeksin Muko

The main active ingredient in this cough suppressant is carbocisteine. This mucolytic completely duplicates the composition of Bronchobos. Libexin Muco is a drug from a French pharmaceutical company. The cost of packaging is on average 460-622 rubles.

If Bronchobos is suitable for the treatment of cough in children over 3 years old, then Libeksin Muko is allowed to be used after 2 years. This medication is not forbidden to use by nursing mothers without interrupting lactation, but pregnant women are not prescribed it.

Fluditek

Carbocysteine ​​cough syrup comes in the form of a syrup and oral solution. The drug has contraindications similar to those of Bronchobos, with the only exception - this remedy can be used in the treatment of cough from 2 years of age. The cost of the bottle is 373-504 rubles.

Elmucin

Mucolytic and expectorant, which comes in the form of gelatin capsules, belongs to the same pharmacological group as Bronchobos. The active ingredient of Emulcin is erdosteine. This drug is not suitable for the treatment of cough in children and adolescents. In case of impaired liver function, the medication is contraindicated. The average price in Russian pharmacies is 360-483 rubles.

Ambrohexal

Inexpensive German cough remedy, which has various forms of release. On sale there is Ambrohexal in syrup, solution for inhalation, tablets and capsules with an active substance called "bromhexine".

The manufacturer does not establish any age restrictions on the use of this product. It is possible to treat cough with Ambrohexal syrup even in newborns. The drug is often prescribed to pregnant women. The cost of 1 bottle of syrup is 77-115 rubles.

Lazolvan

The active ingredient in the syrup is ambroxol. Indications for the use of the drug are respiratory diseases associated with difficult sputum discharge. Treatment with Lazolvan is not possible for people with fructose intolerance. This remedy is also not suitable for children under 6 years of age. The average price in pharmacies is 190-280 rubles.

Althea syrup

Bronchobos is a cough syrup with carbocisteine, which is a chemical. Althea syrup is a natural remedy based on herbal ingredients. The preparation is based on marshmallow root, rich in plant mucus, asparagine, betaine, pectin substances, starch.

The remedy is used not only in the treatment of cough. Althea syrup is prescribed for patients with gastritis, gastric ulcer and duodenal ulcer, as it produces an enveloping, softening, expectorant, anti-inflammatory effect.

The syrup seems to cover the mucous membranes with a thin protective film, protecting them from irritants. The drug can be given to children over 12 years of age. Its approximate cost is 100-150 rubles.

The presented list of analogues that can replace Bronchobos cough syrup is not final.

Among the drugs with mucolytic properties, it is also worth noting:

• Ascoril;
• Mukobene;
• ACC;
• Bronchorus;
• Fluimucil.

Since most of these funds have a completely different composition and a different form of release, the possibility of replacing Bronchobos with one of them should first be discussed with your doctor.

Terms, conditions of sale and storage

The syrup should be kept away from children at room temperature not higher than +25 ° C. The drug should not be exposed to low temperatures. Otherwise, it will lose all of its healing properties.

Subject to the storage conditions, the shelf life from the date of manufacture is 36 months. The cough suspension is available in an over-the-counter form.

Price

In different regions, the cost of the same drug may differ by 1.5-2 times. Bronchobos is no exception: the average price of a syrup with a dosage of 2.5% is at the level of 220–440 rubles, and a bottle of suspension with a 5% concentration of carbocisteine ​​can be purchased for 330–500 rubles. Bronchobos in capsules costs about the same (250-370 rubles. per pack of 30 capsules).

Judging by user reviews, Bronchobos cough syrup for children and adults effectively copes with the task, normalizing the functioning of the respiratory system. The drug rarely causes allergic reactions and is easily taken by children.

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