Euphyllin solution for electrophoresis, injections, inhalations. Instructions for use, dosage, price, reviews

Since Euphyllin's solution is used for various diseases, for the treatment of adults and children, it belongs to drugs with a wide spectrum of action.

Often, the tool is used not only according to the standard scheme, but also for inhalation, electrophoresis with respiratory tract damage. It is not recommended to use the medication on your own, as the risk of developing severe complications increases.

Composition, form of release, where to buy and price

The medicine is available in 2 dosage forms - tablets and solution for parenteral administration and other methods of administration. The tablets are small and white in color, round in shape. They are packaged in blisters of 10 pieces. In a cardboard box there can be 1 or 3 blisters, as well as instructions for the correct use of the medication.

The solution has no color, it is transparent, packaged in ampoules of 5 or 10 ml. An individual carton can contain 5 or 10 ampoules. They are always accompanied by instructions for using the medicine. The solution and tablets contain aminophylline as the main active ingredient.

The tablets contain talc, starch and other active ingredients. The solution contains additional water for injection. You can buy the product at the pharmacy with a doctor's prescription. Its cost ranges from 50-120 rubles. depending on the number of tablets or ampoules in the package.

Mechanism of action

Euphyllin's solution (for electrophoresis and other procedures, the agent is used only as directed by a doctor) has several pharmacological properties. Its mechanism of action is based on the ability to block purine receptors of bronchial smooth muscle fibers.

In addition, the drug reduces the contractility of the muscles of the organ, which leads to a decrease in the risk of developing an attack in chronic obstructive pathologies of the respiratory system.

As a result, the patient's condition improves and the progression of the pathological condition slows down. Additionally, the active substance of the agent stimulates the kidneys, which increases the daily urine output. The antispasmodic properties of the drug can reduce bronchospasm, and also facilitate breathing in patients with obstructive disorders.

The drug also has a stimulating effect on the diaphragm, the respiratory center, which improves the patient's breathing, makes it deeper and lighter by facilitating the functioning of the intercostal muscles.

The medicine improves alveolar ventilation, which leads to an improved oxygen supply to the tissues of the whole body. By improving the nutrition of myocardial tissues, the risk of developing a heart attack, as well as coronary artery disease and angina pectoris, is reduced.

Additionally, the medication expands the peripheral vessels, which improves the flow of blood to the internal organs.

When using the drug, there is a slight decrease in blood in the pulmonary circulation, which facilitates breathing in asthma and other pathologies of the bronchi and lungs. The diuretic effect of the drug is explained by the ability of the drug to increase blood circulation in the kidneys.

There is a moderate effect of the drug on the bile ducts. Contributing to their expansion. The drug also reduces the contractility of the myometrium, which is positively reflected in various diseases of the female reproductive system.

When using a solution, the active ingredient spreads rather quickly through the systemic circulation and has a therapeutic effect. It is worth noting that when using tablets, absorption is also fast, absorption occurs in the digestive tract, namely in the small intestine.

Aminophylline binds approximately 60% to blood plasma proteins. This indicator of bioavailability is not considered high, but the agent is highly effective, despite it. After spreading through the systemic circulation, most of the active substance is concentrated in the lung tissue, which explains the high efficiency.

Experts note that in patients with liver cirrhosis, the bioavailability of the active ingredient does not exceed 35%. Despite this, the medication is well absorbed, but the effectiveness is somewhat reduced.

After processing of the active substance in the liver, it is excreted. The evacuation period takes up to 2 days, depending on the characteristics of the patient's body. In patients with mild liver lesions, excretion is somewhat prolonged. The main amount of the active substance is evacuated with the help of the kidneys, a small part is excreted with feces.

It is noted that absorption and excretion depends on the dose taken and the duration of the drug. When using the drug for electrophoresis or inhalation, absorption into the systemic circulation is negligible. This complicates the study of pharmacokinetic properties.

Indications for use

Euphyllin's solution (for electrophoresis, the agent is used after examination) is indicated for many diseases in adults and children.

The main indications for use are the following:

• Cerebrovascular insufficiency with brain damage and severe symptoms.
• Increased blood pressure in the pulmonary circulation.
• Bronchial asthma at various stages.
• Obstructive forms of bronchitis, which aggravate the condition of the bronchi.
• Chronic bronchitis with frequent relapses.
• Migraine with regular exacerbations of the condition.
• Left ventricular failure in patients with chronic diseases of the cardiovascular system.
• Bronchospasm against the background of inflammatory pathologies of the bronchi and lungs.
• Emphysema of the lungs. In this case, the medication can be used for acute and subacute pathology, which occurs as an independent disorder or against the background of other diseases.
• Chronic obstructive pulmonary disease in patients whose professional activity is associated with regular contact with dust or harmful substances.
• Joint and bone pathologies, for example, osteochondrosis, arthrosis.

As part of the complex treatment of other diseases, the solution can also be used, but according to the doctor's prescription.

Why can Euphyllin be prescribed during pregnancy?

During pregnancy, the drug is used quite often, especially with a severe course of this period. Such treatment is prescribed for toxicosis, as well as an increase in blood pressure.

With placental insufficiency, severe edema of the extremities, the remedy is also prescribed. This is due to the ability of the solution to stimulate blood circulation in the myometrium, as well as improve blood circulation in the kidneys, which increases daily urine output and helps eliminate edema.

There is no specific scheme for using the product during the gestation period, since the official instruction is considered a contraindication. However, the experience of many specialists proves that with the right choice of dose and adherence to all the rules, the remedy can bring benefits to the pregnant woman and alleviate the condition.

Contraindications and side effects

Euphyllin's solution and tablets are not used for inhalation, electrophoresis and other methods when allergies to the components of its composition are detected.

There are other contraindications for therapy:

• A severe form of renal failure, in which the functioning of the organ is severely impaired.
• Acute myocardial infarction and severe angina.
• Atherosclerotic vascular changes.
• Pulmonary edema on the background of cardiac pathologies.
• Acute peptic ulcer of the duodenum and stomach.
• Epilepsy with regular seizures.
• Hemorrhagic stroke.
• Uncontrolled arterial hypertension or hypotension. The drug is not contraindicated in mild cases of such diseases, but with frequent relapses and attacks, it should not be used.
• Hemorrhage in the retinal tissue of the visual apparatus.
• Disorders of the thyroid gland, manifested in the form of thyrotoxicosis or hypothyroidism.
• Sepsis in acute or subacute form.
• Acute bleeding, the presence of such disorders in the patient's history.
• Convulsions of unspecified origin or arising on the background of neurological pathologies.
• Paroxysmal tachycardia and extrasystole.
• Acute heart failure.

The agent is used with caution in severe gastritis, pancreatitis and cholecystitis.

If the instructions are violated, negative reactions from the internal organs and systems may develop. Complications can occur if all recommendations are followed.

Organs and systems	Most common complications
Nervous system	Headaches, dizziness when using the drug are quite common. Sometimes patients report severe weakness, sleep disturbance and fatigue. The patient's performance decreases, he spends most of his time in a horizontal position.
Vessels and heart	Tachycardia and arrhythmia during treatment occurs in most cases in adults. The condition can be aggravated by a decrease or excessive increase in blood pressure indicators, as well as disorders of the hematopoietic system.
Digestive tract	When treating with a solution, heartburn may occur, the symptom does not depend on food intake. In addition, nausea, pain in the stomach and intestines may appear, and appetite worsens. Some people report intense thirst, dry mouth and gas, diarrhea, or persistent constipation.
urinary system	Frequent urination when using the solution may be accompanied by the appearance of blood impurities in the urine, as well as pain in the kidney area. As a rule, the urge to empty the bladder appears in patients at night, even when drinking a small amount of liquid.
Skin	Allergy to the remedy manifests itself quite often, accompanied by a rash, severe itching and burning. When scratching, areas of irritation and peeling appear on the skin. When you stop using the drug, the symptoms may disappear or worsen.

The severity of negative reactions depends on the organism of a particular patient. In some patients, the manifestations disappear immediately after the termination of the course, but in many they are aggravated. With the development of complications, it is important to visit a doctor who will prescribe symptomatic therapy to normalize the condition.

Electrophoresis with Euphyllin

Euphyllin solution for electrophoresis is used to treat various pathologies of the respiratory system, as well as the musculoskeletal system. The treatment regimen for children and adults is different, so it is important to consult a doctor beforehand.

It is worth remembering that in acute diseases of the skin, the use of electrophoresis can provoke complications.

Baby

Babies older than 1 month are prescribed electrophoresis procedures for muscle hypertonia associated with various neurological disorders. Due to the point effect on the affected tissues, systemic negative reactions develop quite rarely.

The procedure takes up to 10 minutes. The specialist moistens a gauze napkin, folded several times, in Euphyllin's solution, and then applies it to the affected area. Electrodes are applied to the napkin, which, using electrical impulses, deliver drug particles to the affected tissues.

As a result, their regeneration occurs, spasm and pain are eliminated. Such procedures contribute to a speedy recovery. The course consists of 10 sessions with a frequency of 2-3 days.

To kid

For children, the procedure is performed for muscle damage, neurological disorders and other pathologies. The procedure is carried out according to the standard scheme once every 3 days for a month. The result is tissue restoration and improved blood circulation in the area of ​​exposure to electrical impulses.

Gauze wipes with a solution are applied to the affected area, electrodes are applied on top. The procedure for children from 3 years old lasts 15 minutes. it is allowed to repeat the course 1 time in 6 months.

Adult

For adults, procedures are prescribed for osteochondrosis, arthrosis, during the recovery period after injuries of the extremities and damage to muscles and ligaments.

The course of treatment involves the passage of 15-20 procedures with a frequency of 1 every 3 days. The session lasts 20 minutes. It is carried out according to the standard scheme, that is, electrodes are applied to the affected area, under which gauze wipes soaked in a medicinal solution are previously placed.

During the session, low-frequency electrical impulses deliver medication particles to the area lesions, which leads to rapid tissue repair and prevents further progression states.

Inhalation with Euphyllin

Euphyllin's solution for electrophoresis is often used. However, the appropriateness of using the drug for inhalation should be determined by the doctor.

As a rule, experts have a negative attitude to this method, since when the vapor of the agent settles on the mucous membranes, it does not enter the systemic circulation. But it is precisely when the components enter the blood that the therapeutic effect is carried out.

Despite the prohibitions of doctors, many adults treat themselves this way and even treat their children. As a rule, a nebulizer is used, into which 2 ml of Euphyllin's solution and 3 ml of saline 0.9% are poured. After that, the procedure is carried out for 7 minutes.

The course consists of 5-10 sessions, which are repeated daily. Pediatricians strongly discourage this method of treatment for children.

Injections

The most effective method of therapy is intravenous infusion of the solution. First, it should be diluted in 0.9% saline solution. A single dosage of the product for an adult is 3 ml. One syringe is filled with 3 ml of solution and 7 ml of sodium chloride.

Intravenous infusion is carried out slowly, it can be repeated no more than 2 times a day. For pregnant women, the dosage is selected individually in each case, due to the lack of data on the use of the drug during this period.

Since this period is considered a contraindication in the official instructions, it does not describe the rules for using the solution for women during gestation. This means that in each case, the doctor independently decides on the duration of the course and the prescribed dose.

Children under 3 months are allowed to enter no more than 60 mg of the drug per day. It is worth knowing that 1 ml of solution contains 240 mg of aminophylline. Children older than 3 months may increase the dose, but this is done only by a pediatrician based on examination data.

Patients from 1 year to 9 years old are administered 5 mg of the drug per 1 kg of body weight per day. Patients over 9 years old and up to 12 years old are prescribed 6 mg of the drug per 1 kg of weight. Children over 12 years old are taken from 4 to 7 mg of the drug per 1 kg of body weight per day. In each case, the dose may vary depending on the disease. The drug is administered intramuscularly very rarely.

Frequency of application and duration of the course

With electrophoresis, the course consists of 5-20 sessions with a frequency of 2-3 days. The maximum duration of treatment by inhalation should not exceed 10 days of regular use.

Injection therapy lasts from 10 to 20 days, depending on the patient's condition. Injections are done intravenously 1-2 times a day. In each individual case, the duration of the course may increase, but the decision is made only by the doctor.

special instructions

When using a solution for inhalation, it is important to first consult with a specialist. As a rule, doctors prescribe other drugs that are highly effective. With electrophoresis, it is important to follow all the rules, especially in the case of treating a baby or a preschool child.

The specialist from time to time asks the patient about his health, if negative reactions appear, it is important to immediately stop the procedure. With prolonged use of the solution and its intravenous infusion, the doctor monitors blood pressure indicators, and also examines the blood, urine in order to identify complications from the kidneys.

It is strictly forbidden to inject the agent intravenously without preliminary dilution with saline, since complications from the vessels may develop. With intramuscular injection, a lump or even an abscess may form in the area of ​​injection.

Drug interactions

The use of Euphyllin in combination with anticoagulants and some antibiotics is not recommended. You should not use the medication at the same time as solutions that contain fructose or glucose, since the development of negative reactions is noted.

It is not recommended to carry out treatment with Euphyllin and to administer local anesthetics to the patient.. This combination can lead to complications. In each case, the doctor decides on the combination of one or another medication. If the patient is taking any medication on an ongoing basis, it is worth informing the doctor about this.

It is forbidden to draw Euphyllin and any other medicinal solution into the syringe. Saline is considered an exception.

Shelf life of the drug

Store the medicine in a dark, cool and dry place. It is important to limit access to children and direct sunlight.

The maximum shelf life of the product is 2 years. It is forbidden to use the medication after this period has expired.

Such a popular medication as Euphyllin's solution is used to treat children and adults. The use of an injection agent, electrophoresis and other procedures is shown. But only as prescribed by a doctor and in the absence of contraindications.

Video about Euphyllin solution

Ampoules of Euphyllin - overview and indications: