Lugol solution with glycerin. Instructions for use for children, adults, price, reviews

Lugol - liquid iodine preparation, dissolved in glycerin, intended for the treatment of infectious lesions and inflammation of the oropharynx, ENT organs, skin.

Most often, the agent is used to sanitize the tonsils, cleanse the lacunae from purulent contents and plugs with tonsillitis, chronic or recurrent tonsillitis. Lugol has remained one of the safest and most effective medicines for its group for decades.

Indications for use

The drug Lugol belongs to the category of local and external antiseptics. A solution of glycerin is a viscous, but quite fluid brown liquid with a specific smell and taste of iodine.

Due to the absence of alcohol in the composition, it is permissible for use in pediatrics, does not burn mucous membranes, and is able to remain on the treated surfaces for a long time. The glycerin-based solution disinfects well, but does not dry out tissues, which speeds up the process of subsequent regeneration.

Indications for Lugol's use in various ways:

Outwardly	Locally	Inside
Wounds, Injuries Any damage to the skin Myalgia (muscle pain) Burns (including chemical burns) Secondary infection	Tonsillitis (acute, recurrent, chronic), Atrophic rhinitis Burns of mucous membranes, Purulent otitis media Non-healing (trophic) ulcers	Tertiary (chronic) syphilis, Epidemic goiter Atherosclerosis (as part of therapy and as prevention)

Lugol with glycerin, due to the presence of iodine, has a moderate local irritating, strong antiseptic and antifungal effect. A distinctive feature of the tool is that sensitive pathogens are not able to develop resistance to it.

Compound

The active ingredient in Lugol's composition is Iodine (iodine), present in an amount of no more than 1%, the rest of the volume is made up of additional substances. Molecular Iodine is dissolved in a small amount of purified water and diluted with a glycerin base.

Lugol's excipients:

• glycerin (94% of the total mass) - softens the effect of iodine;
• water (3%) - as a neutral solvent;
• potassium iodide (2%) - improves the solubility of iodine.

Lugol (solution with glycerin) is active against most gram-negative, gram-positive pathogens and fungi. The drug is considered a universal antiseptic that is not addictive and rarely leads to side effects.

In what form is it produced

To date, a glycerin iodine preparation is produced in one pharmaceutical form - a liquid solution. The only difference is the way of packaging Lugol and the device for application. The glass bottle may come with a dropper dispenser or spray nozzle. The composition of the preparation for topical application and the spray are completely identical.

Lugol is packaged in bottles (25, 30, 50, 100 or 200 ml) with a tight stopper and a screw cap. The containers are placed in cardboard boxes with the mandatory enclosure of instructions. The spray preparation is provided with a spray nozzle. The price of Lugol's solution for local use (25 g bottle) varies from 30 to 94 rubles. The cost of the spray does not exceed 150 rubles.

Pharmacodynamics

Elemental iodine after entering the blood reveals its effect mainly in the thyroid gland. With a lack of iodine in the body and the environment, the substance from the drug is quickly absorbed and maintains the production of thyroid hormones, with sufficient concentration - blocks the sensitivity of the thyroid gland to TSH pituitary gland.

Influence of Lugol, as an iodine preparation, on metabolism:

• stimulates the process of decomposition of complex organic compounds into simple ones;
• reduces the concentration of lipids and cholesterol in the blood;
• accelerates the dissolution of blood clots;
• slows down blood clotting.

Excreted through the excretory glands, iodine enhances their secretion, exerting an expectorant effect, increasing salivation. At small doses it stimulates lactation, at large doses it inhibits.

The external action of Lugol is due to the ability of iodine to destroy pathogenic microorganisms: gram-positive, gram-negative bacteria, fungi (including candida), yeast, with prolonged use - staphylococci.

The drug does not work on Pseudomonas aeruginosa. Iodine is also irritating and, when applied to large areas, is absorbed into tissues and absorbed into the bloodstream (resorptive effect).

Pharmacokinetics

When Lugol comes into contact with the body, elemental iodine is partially absorbed, carried through the body with the bloodstream, but is accumulated mainly by the thyroid gland. Excretion occurs through the skin with sweat, through the intestines or kidneys. A small proportion of iodides are found in breast milk.

Spraying Lugol on the mucous membranes of the throat, nose, skin is safe in correctly calculated doses. The drug is low-toxic, its resorption with local and external application is negligible. High absorption is noted when the solution is swallowed.

Application

When applied externally, Lugol is applied only to inflamed areas or areas affected by infection. In surgical practice, gauze napkins are impregnated with a solution to be applied to wounds or burns up to 3 times a day.

Topical application includes spraying, instillation, rinsing of the mouth, pharynx, ear and nasal passages. Internal administration is dosed individually as prescribed by the attending physician in accordance with the disease and age.

After applying Lugol to the mucous membranes of the oropharynx, do not drink or eat for at least 30 minutes. The drug must remain on the treated surface for a therapeutic effect. For external treatment, the solution is left on the skin for up to 15 minutes, after which a bandage is applied or the surface is left open.

For children under 18

Lugol (a solution with glycerin) is considered a gentle antiseptic, therefore, local application to mucous membranes and skin is used in pediatrics almost from birth. Internal admission is allowed only under strict indications for children over 5 years of age. The first application is carried out in a minimum amount, tracking the child's individual reaction to iodine.

Long-term use for patients of all ages has proven the effectiveness and safety of the product. Lugol is not addictive, microorganisms do not develop resistance to it, so the agent can used for therapy for all types of infections and does not show adverse reactions characteristic of antibiotics.

Most often, Lugol is prescribed for children with pharyngitis or sore throat for mechanical cleaning of the tonsils and throat treatment. The medicine in the form of a spray is irrigated with inflamed areas several times a day, or the lacunae are washed once a day. For the treatment of children under 3 years old, it is more advisable to apply Lugol with a special brush, spatula or cotton swab, since the spray can enter the bronchi when inhaling.

To exclude a mucosal burn, which sometimes occurs in children when treated with Lugol, for patients under 4 years of age, the drug is recommended to be diluted with saline twice. Such a solution is approved for use for gargling in older children.

For adults

Local use of Lugol for adults involves the following procedures:

• washing lacunae for tonsillitis - daily for up to 5 days at intervals of 2 days;
• spraying the throat for inflammations and infections - up to 6 times a day until the condition is relieved;
• irrigation of the nasopharynx - 3 times a week for 2-3 months;
• instillation of ears - a few drops per day for no more than 4 weeks in a row.

External treatment of wounds, ulcers, infected burns, erysipelas is carried out on the recommendation of a doctor, depending on the extent of the lesion. Small damages can be sprayed or lubricated up to 6 times a day. Large areas are processed 2-3 times a day. Lotions on wounds are changed as needed.

For pregnant

Among the official contraindications to the use of Lugol, pregnancy is indicated at any time and during lactation. In practice, the doctor may allow local or external use of the drug if other types of therapy are more dangerous for the mother and fetus. Internal reception in these conditions is completely excluded.

For the elderly

Lugol solution with glycerin can be used according to indications in adulthood. In this case, all contraindications to the use of the drug, the presence of chronic kidney or liver damage, and the functioning of the thyroid gland must be taken into account. Age-related changes in themselves are not grounds for canceling iodine-containing drugs, but their dosage should be very careful.

Contraindications

Do not appoint Lugol with a known sensitivity to iodine and hyperfunction of the thyroid gland.

In addition to pregnancy and infancy, there are such contraindications to the internal intake of the drug and abundant external application:

• tuberculosis;
• boils, acne;
• thyrotoxicosis;
• purulent skin lesions;
• diathesis with a tendency to bleeding;
• hives.

Lugol is prohibited for use in the presence of adenomas of any localization, decompensated liver or kidney pathologies, nephritis, nephrosis.

Overdose

Lugol, with prolonged use or a single dose in an increased dose, can provoke iodism.

The state of excessive accumulation of iodine in the body is accompanied by the following symptoms:

• increased salivation;
• constant thirst;
• runny nose, cough;
• itching, burning;
• rash, dry skin;
• metallic taste in the mouth;
• swelling;
• bronchospasm;
• nausea, vomiting.

When such symptoms appear, sorbents should be drunk: potato starch, activated carbon. As an antidote, you can take soda diluted in water, milk, jelly. If you experience tachycardia, seizures, a drop in blood pressure, a threadlike pulse, you should immediately consult a doctor.

Side effects

When applied externally, undesirable side effects are extremely rare and are expressed by slight irritation at the site of application. Treating large areas of the body for a long time can lead to iodism.

Local application, especially the treatment of mucous membranes, can provoke more serious reactions: burning, swelling, up to Quincke's edema, fever, headache. Reactions to Lugol most often subside on their own or are stopped by antihistamines.

In patients over 45 years of age, the use of iodine-containing drugs (in particular, Lugol) may be accompanied by sleep disturbances, anxiety, increased sweating, salivation, and diarrhea.

Drug interactions

Lugol (solution with glycerin) is incompatible with compositions containing natural aromatic oils, white mercury, metal salts, ammonia. The agent weakens the effect of lithium preparations. The presence of blood, as well as pus or fat on the treated surfaces reduces the antiseptic effect of the solution. An acidic or alkaline environment adversely affects the work of the drug.

External application of Lugol at the same time as other disinfectants (for example, hydrogen peroxide) is not recommended, as this greatly dries up tissues and increases side effects. Especially carefully, you should alternate the solution with alcohol-containing agents.

Storage conditions and periods

Molecular iodine in the composition of the drug requires its storage in a cool, dark place, otherwise the substance is destroyed. The optimum temperature for storing "Lugol" is from +18 to +25 ° C. The shelf life with proper storage of the solution is 3 years.

The solution should be kept in its original packaging, tightening the cap tightly after each use. It is advisable to place vials with Lugol in a box and store in places where children or pets cannot get it.

Conditions of dispensing from pharmacies

Glycerine iodine solution (Lugol) is available at any pharmacy without a prescription.

Analogs

Lugol, in the form of an antiseptic glycerin solution, according to the principle of action and purpose, can be replaced by one of the following medicines.

Malavit

The drug is a liquid solution intended for topical use. Malavit is produced in darkened glass containers with a volume of 30 and 50 ml. Based on glycerin and ionized water, a complex elixir with the addition of the following ingredients:

• Siberian cedar extract;
• copper preparations;
• stone oil;
• organic acids;
• extracts of many medicinal plants (including chaga, birch, oak).

Rich balanced composition of Malavit has such an effect on the body:

• anti-inflammatory, decongestant, analgesic;
• regenerating, restoring tissue function;
• regulating effect on the glands (sweat and fatty);
• normalizing metabolic processes;
• increasing local immunity.

For treatment, the solution is diluted or used in pure form. The whole preparation is applied to intact skin (without wound surfaces). For wounds, scratches, infected areas, the drug is diluted with clean water in proportions from 1: 5 to 1:20 according to indications. The duration of the course is determined by the severity of the condition and is prescribed by the doctor.

Locally used for seasonal infections, acute respiratory infections, acute respiratory infections, Malavit is diluted with 5-10 drops in half a glass of water and applied to the mucous membranes. Use a solution for rinsing, rinsing the lacunae. The drug in its pure form is rubbed on the back and chest, and the nasal passages are treated.

Children under 5 years old Malavit are bred, counting the number of drops by the number of years. The cost of the drug in the pharmacy does not exceed 150 rubles per bottle.

Orasept

The product is created on the basis of phenol (active substance) with the addition of water, glycerin, sweetener, flavor and color. The drug is released in the form of a spray, each milliliter of which contains 14 mg of phenol. Orasept can be called a syrup: it is a sweet liquid with a cherry flavor. The product is packaged in 177 ml vials with the attachment of a spray bottle.

The drug exhibits the following properties:

• fungicidal (antifungal);
• emollient for mucous membranes;
• anti-inflammatory;
• eliminating inflammation and edema.

The active substances of Orasept do not penetrate into the bloodstream, but only act locally.

The spray is used only orally for the following indications:

• pharyngitis, tonsillitis, tonsillitis;
• for anesthesia of various ENT pathologies;
• gingivitis, periodontitis, stomatitis;
• post-surgical treatment in dentistry;
• prevention of inflammation of the oral cavity in the presence of prostheses, braces, and other devices.

There are several strict contraindications for the use of Orasept: age up to 2 years, individual intolerance to ingredients, severe kidney pathologies.

Instructions for the use of Orasept:

• children from 2 to 12 years old are prescribed 3 injections no more often than every 3 hours;
• during pregnancy, Orasept can be used according to strict indications, during lactation it is prohibited;
• adults are prescribed up to 6 injections every hour until the condition improves, then - 4-6 doses up to 6 times in 24 hours.
• the duration of treatment and the exact dosage is determined by the doctor.

The drug accumulating in the mouth is allowed to be swallowed. Apply the spray only to irrigate the mouth and throat. The price of Orasept in the pharmacy network varies from 250 to 400 rubles per bottle.

Stopangin

The drug is based on hexetidine with the addition of essential oils (eucalyptus, mint, anise, orange, and other plants), and also contains ethanol, saccharin and methyl salicylate. Stopangin is released in the form of a spray or solution that has an antiseptic effect.

The main properties of Stopangin:

• antiviral;
• antibacterial;
• fungicidal;
• enveloping;
• locally irritating;
• anti-inflammatory;
• moderate anesthetic.

All ingredients of the complex preparation are excreted with saliva, without penetrating into the systemic circulation. The effect of a single use of the product lasts more than 10 hours.

Indications for the appointment of Stopangin:

• infections of various origins localized in the oropharynx;
• treatment of burns or injuries to the skin and mucous membranes;
• prevention in dental practice;
• prevention of superinfections in tumor processes in the oral cavity, larynx.

Contraindications to the use of Stopangin are atrophic pharyngitis, allergy to drug components and age up to 8 years. The drug is applied with a swab or sprayed on the affected areas no more than 2 times a day. To enhance the effectiveness, use the remedy after meals, avoiding drinking or snacking for several hours.

The price of Stopangin in the form of a spray does not exceed 200 rubles. The cost of the solution ranges from 120 to 140 rubles.

Yodovidone

Lugol (solution with glycerin) has several iodine-containing analogs, one of the most popular among them is Iodovidone. A balanced complex of polyvinylpyrrolidone-iodine that reliably binds molecular iodine and promotes its gradual release upon contact with mucous membranes or skin.

The tool is released in the form of a spray. At the site of application of Iodovidone, a colored layer is observed, which becomes thinner, becoming transparent as the composition is absorbed. Discoloration signals the end of the drug action.

Iodovidone is effective against bacteria (including tuberculosis pathogens), protozoa, viruses, fungi.

Indications for use in surgery are any invasive procedures, operations, studies in violation of the integrity of the skin, sterilization of instruments, handling of the hands of personnel and surgeons.

Indications for topical application:

• infections of the oral cavity, nose, pharynx;
• prevention of secondary infection, burn surfaces, wounds, purulent lesions;
• trichomoniasis, nonspecific vaginitis.

Dosing is individual and depends on the specificity of the disease, the severity of the condition, age, and the presence of contraindications.

The use of Iodovidone is not allowed in such conditions:

• impaired renal function, renal failure;
• pregnancy and breastfeeding;
• infancy;
• allergy to iodine;
• hyperthyroidism.

The drug has a lot of restrictions on its use with other medicines. Its use should be definitely discussed with your doctor.

The cost of Iodovidone (0.5%) in the form of a spray is about 110 rubles per bottle of 30 ml.

Lugol is a reliable and safe means for disinfecting mucous membranes and skin. The drug remains one of the most prescribed for lacunar tonsillitis in adults and in pediatrics. A solution of molecular iodine with glycerin due to its simple composition has few side effects and restrictions on intake, but requires attention to the dosage due to its direct effect on the thyroid gland.

Video about Lugol's solution

Overview of Lugol's drug solution with glycerin: