Reamberin. Indications for use, instructions, analogs, what they are prescribed for, price, reviews

Reamberin is a drug used to treat toxic damage to the body. The drug is used only when indicated and under the guidance of a treating specialist.

Forms of release and composition of the drug

This medicine is produced by a Russian pharmaceutical company in the form of an infusion solution. Its main substance is sodium meglumine succinate.

Additional composition:

• 6 g sodium hydrochloric acid;
• 0.3 g of potassium chloride;
• 0.12 g magnesium chloride;
• 1,788 g of caustic soda;
• up to 1 liter of water for injection.

The medicine is contained in glass ampoules and packed in a cardboard container.

Pharmacological properties

The solution belongs to the group of detoxification medicines.

Pharmacodynamics and pharmacokinetics

The drug exhibits high antihypoxic and antioxidant properties. the therapeutic efficacy of the agent is achieved due to the influence of its components on anaerobic processes in cells. At the same time, the suppression of the production of free radicals and the restoration of the energetic properties of cells are noted.

The active substance enhances enzymatic processes by removing fatty acids and glucose from the body. The medicine restores the pH level in the body and saturates the blood with useful gases. The agent also exhibits low diuretic properties. The components of the solution are quickly excreted from the body and do not accumulate.

Indications for use

Reamberin (indications for use are the main factor in prescribing the drug) should be prescribed only by the attending specialist after all the studies have been carried out.

The drug is used in the treatment of adults and children with hypoxic and intoxication lesions. The tool is highly effective against intoxication lesions of various origins.

Contraindications

The solution has some restrictions on the use associated with the action of the active components or the physiological characteristics of the patient.

Contraindications:

• hypersensitivity to the composition of the product;
• TBI (traumatic brain injury), which are accompanied by the formation of swelling in the area of ​​the brain;
• functional disorders of the kidneys;
• the period of pregnancy and breastfeeding.

Extremely carefully and only with the permission of the attending specialist, the medication can be used in case of violations of the acid-base balance in the body (alcolosis).

At what age can the drug be used?

The drug is approved for use starting from 1 year. However, therapy in this case should be carried out only under the supervision of a pediatric specialist.

Instructions for use, dosage

Reamberin (indications for the use of the drug must be strictly observed when using it) is the main method of therapy for intoxication. The product is intended for intravenous administration.

Adult patients are prescribed a drip injection of the drug no more than 10 μg / ml per day. In this case, the rate of inflow of the solution should be no more than 90 drops per minute.

If necessary or in severe cases, the rate of administration of the solution can be changed according to the indications of the attending physician.

In childhood, starting from 1 year, the dosage is calculated according to the child's body weight - from 6 to 10 ml per 1 kg of body weight. Use once a day. The rate of drug intake should be no more than 3-4 ml per 1 minute. The duration of therapy in both cases is no more than 11 days.

Data on the use of the drug in elderly patients are not provided. Therefore, in this case, treatment begins with lower dosages - from 30 to 40 drops of solution per minute. It is necessary to use the medicine with extreme caution in patients with renal insufficiency.

In the presence of alcolosis, therapy is carried out until the level of acid-base balance is normalized. In this case, the daily dosage is calculated on an individual basis.

Side effects

If the solution is used incorrectly or the daily dosage is violated, negative reactions may develop.

Side effects:

• Local reactions in the area of ​​administration of the drug: weakness of the body, increased sweating (hyperhidrosis), the formation of edema, chills, the development of hyperthermia. The formation of irritation and redness at the injection sites, the development of phlebitis and painful sensations are also noted.
• Immune system disorders: various allergic manifestations, angioedema, anaphylaxis.
• Disturbances from the skin of the subcutaneous tissue: rash, itching, urticaria.
• Changes in respiratory functions: the development of shortness of breath and dry cough.
• Disruptions from the cardiovascular system: development of shortness of breath, palpitations, increased heart rate, pain in the heart or chest area.
• Violations of the vascular system: a decrease or increase in blood pressure, the development of redness and irritation in the upper body. These reactions go away on their own.
• Disruptions on the part of the digestive system: the development of vomiting and nausea, soreness in the epigastric region, a metal taste in the mouth, diarrheal syndrome.
• Disorders from the central nervous system: the occurrence of dizziness and migraines, tremors in the body (tremor), convulsive states, paresthesias, increased excitability, restless feeling.

With the development of a negative effect, it is required to reduce the rate of entry of the solution into the body. In case of the formation of undesirable manifestations that are not noted in the annotation, it is necessary to consult with the attending specialist.

Overdose

Reamberin, if the prescribed dosage is exceeded, can lead to the development of arterial hypotension..In this case, it is required to abandon the further use of the solution and seek medical help for the appointment of symptomatic therapy. When carrying out symptomatic treatment, the use of various drugs is indicated. Gastric lavage, diuresis and sorbing agents are not effective.

If necessary, hypertensive drugs, polyglucin or calcium chloride can be prescribed to eliminate the signs of an overdose.

special instructions

When prescribing a medication, it is necessary to take into account that its active substance can lead to a decrease in the level of glucose in the blood, as well as contribute to an increase in the content of alkali in the blood and urine. This action is due to the influence of the main substance on the anaerobic processes in the body.

It should also be borne in mind that the solution contains sodium. In this connection, patients who are on a diet that excludes sodium intake should use the drug with extreme caution.

The solution contains potassium. This should be taken into account when prescribing the drug to patients with reduced renal function or on a diet that excludes potassium intake.

Patients suffering from diabetes mellitus or patients with glucose intolerance during the period of use solution, it is necessary to systematically undergo studies to determine the glucose level in blood.

Before using the medicine, you must make sure that there is no sediment or foreign impurities in the vial (ampoule). In the presence of such elements, it is necessary to abandon the use of such a solution.

During the period of using the solution, it is recommended to refrain from driving a car or carrying out work requiring high psychomotor reactions.

Drug interactions

The drug can be administered in conjunction with antibiotics, glucose and water-soluble vitamin complexes. In some cases, such a combination is necessary.

When using other medications during the period of administration of the solution, it is recommended to inform the attending specialist about this in advance. Such measures will help to avoid possible drug interactions.

The joint use of the drug with calcium succinate should be avoided, since with such an interaction, a precipitate of the second medication may form.

Analogs

Reamberin (indications for the use of the drug indicate the possibility of using the drug in childhood) can lead to the development of allergic reactions, especially in children. In this connection, in the event of such reactions, the solution should be replaced with another similar agent.

Analogs:

• Xylate. This medicine is produced in the form of an infusion solution for drip administration. The drug is a multicomponent drug based on sodium acetate, magnesium chloride, potassium chloride, calcium chloride and magnesium chloride. The medication is used for intoxications of various origins, to restore microcirculation, as well as to replenish the deficiency of carbohydrates. The solution is also used in the pre- and postoperative period, various infectious diseases and the toxic form of hepatitis. The medication is forbidden to use in case of dehydration of the body, violation of the water-electrolyte balance. Other contraindications: the formation of edema, hemorrhagic processes, cardiovascular pathologies in the stage of decompensation, thromboembolic syndrome. Adults are prescribed 40-60 drops of solution per minute. (the rate of administration may vary depending on the tolerance of the agent). In this case, the daily dosage should not exceed 2100 ml. The duration of therapy depends on the identified disorder. Conditions for the sale of funds - by prescription. The cost of the solution in public and private pharmacies is from 230 to 330 rubles.
• Zorex. This pharmacological agent is produced by a Russian pharmaceutical manufacturer. The active component of the drug is dimercaprol. The medicine belongs to the category of complexing agents and is produced in the form of capsules for oral administration. The drug has high detoxification, antioxidant, hepatoprotective properties. A medication is used for toxic lesions caused by the use of alcohol, heavy metals, arsenic, as well as drugs belonging to the class of glycosides. In case of metal poisoning, 300-1000 mg is prescribed, divided into 2-3 equal doses. The duration of the course is no more than 1-1.5 weeks. Contraindications to the appointment of capsules are the following violations and conditions: functional decompensated kidney or liver disorders, juvenile age, reactions hypersensitivity. Capsules can be used with extreme caution with high blood pressure. The terms of the sale of the tablets are by prescription. Prices for the product in regional and regional pharmacies vary between 400-520 rubles. per packing.
• Neohemodesis. This medication is a multicomponent medication that comes in the form of an infusion solution. The medicine belongs to the category of detoxification drugs and is used in the following cases: toxic damage gastrointestinal tract, septic lesion, intestinal obstruction, burn conditions, exogenous forms poisoning. The solution is injected intravenously at 40-80 drops per minute. A single dosage is determined by the treating specialist based on the severity of the disease and the age of the patient. For children, the drug is also prescribed intravenously. However, the dosage is calculated taking into account the child's body weight. The maximum duration of therapy is 1.5 weeks. The minimum treatment period is 1 day. Contraindications: intracranial pressure, intolerance to the composition, trauma and damage in the head area, hemorrhagic stroke, heart failure (in chronic form). The medication is also forbidden to use in case of a depressed state of the respiratory system, thromboembolic syndrome, acute nephritis, insufficient amount of urine flow, with bronchial asthma, phlebothrombosis, and also during feeding child. The conditions for dispensing the solution from pharmacies are prescription. The cost of a medicine at regional pharmacies in Russia is from 30 to 200 rubles.
• Meglumine sodium succinate. This medication is made in the form of an infusion solution for oral administration. Its active ingredient is the eponymous component of meglumine sodium succinate. The drug exhibits high detoxification and antihypoxic properties. Indications for the administration of the solution: exogenous and endogenous forms of intoxication. The agent is administered using a dropper. The injection rate should be no more than 90 drops per minute. The maximum daily dose should not exceed 400 ml. The duration of treatment can vary from 7 to 11 days. In childhood, the daily dosage is calculated according to the identified violation and the child's body weight. The duration of the course is from 1 to 1.5 weeks. Restrictions on the use of the medication are intolerance reactions, the presence of injuries and injuries in head area, chronic kidney failure, and the period of gestation or feeding child. The terms of sale of the medicine are according to the doctor's prescription. The cost of the solution in Moscow pharmacies ranges from 80 to 5000 rubles. depending on dosage and volume.
• Reambisar. This medication is made on the basis of sodium succinate meglumine in the form of a solution for intradroplet administration. The tool belongs to the class of detoxification drugs and is used for exogenous and endogenous intoxications. It is approved for use in children from the age of 1 year. In this case, the treatment of children should be carried out only in a hospital setting. Contraindications: the period after traumatic brain injury, intolerance to the composition, the period of gestation or breastfeeding, as well as kidney or liver failure, proceeding in a chronic form. No more than 400 ml of solution is prescribed per day. In this case, the rate of drug administration should not exceed 90 drops per minute. The therapy is carried out for 1-1.5 weeks under the supervision of a stationary doctor. The conditions for the sale of the medication are according to the doctor's prescription. The cost of ampoules (vials) in Moscow pharmacies ranges from 350 to 2340 rubles.

Reamberin (indications for the use of the solution should be established by the attending specialist) should be replaced with other similar drugs only after prior consultation with a doctor. It is forbidden to independently select analogues, since such use of medicines can cause the development of severe allergic reactions.

Terms, conditions of sale and storage

• The infusion solution must be stored in a dry and clean place at temperatures up to 25⁰ C.
• The shelf life is 3 years from the date of manufacture. After opening, it is recommended to use the medication for the next month.
• Do not use the product after the expiration date indicated on the package.
• Ampoules are dispensed with a doctor's prescription.

Price

The cost of the solution depends on the dosage produced, as well as the retail pharmacy chain that dispenses and sells medicines. You can clarify the availability of the drug, as well as its cost, at any pharmacy located in the patient's place of residence.

Sales area / region	Dosage form / dosage	Price
Moscow, Moscow region	Solution, 1.5%, 200 ml	RUB 75-768
St. Petersburg	Solution, 1.5%, 250 ml	RUB 125-4900
Saint Petersburg (suburbs)	Solution, 1.5%, 400 ml	RUB 164-3330
Leningrad region	Solution, 1.5%, 500 ml	RUB 160-3301
Novgorod region	Solution, 1.5%, 200 ml	80-590 rub.

Before using Reamberin, you must consult with a specialist and familiarize yourself with the indications for the use of the solution. Additionally, it is recommended to study the reviews of patients who used the remedy for intoxication.

Video about droppers from intoxication

Good hangover drip: