Undevit vitamins. Reviews of doctors, instructions for use, what they take, composition, price

For replenishing the lack of vitamins, activating physiological processes and enhancing cellular regeneration, take Undevit. The well-known and popular drug has received a large number of reviews. They note the effectiveness and safety of the multivitamin complex.

Release form and composition of the drug

Therapeutic and prophylactic medication is produced in the form of a yellowish dragee with a pleasant sour taste. The drug is delivered to pharmacies in cylindrical plastic containers with a flat screw cap.

Each package is accompanied by instructions with the composition, brief characteristics and rules for the use of the medicinal product. The medication is produced by the domestic pharmaceutical company Pharmstandard OJSC.

Undevit - vitamins, reviews of which are mostly favorable. Each container contains 50 units of the drug. The drug has a rich and balanced composition. It is able to satisfy the daily requirement of the body for vitamins established by the WHO.

Composition of the preparation:

Component	Content in 1 tablet, mg	Daily requirement,%
Retinol (vitamin A)	3,33	100
Thiamine hydrochloride (B1)	2	200
Riboflavin (B2)	2	100
Nicotinamide (RR)	2	100
Calcium pantothenate (B5)	3	60
Pyridoxine (B6)	3	250
Folic acid (B9)	0,07	35
Cyanocobalamin (B12)	0,02	83
Ascorbic acid (vitamin C)	75	83
Tocopherol (vitamin E)	10	83
Rutin (vitamin P)	10	100

The following excipients are included in the chemical formula of the medication, ensuring homogeneity, the desired consistency and taste of the multivitamin complex:

• beeswax, which has anti-inflammatory and antibacterial properties;
• wheat flour - accelerates metabolic processes, stimulates brain functions and reduces the risk of developing gallstone disease;
• liquid paraffin - softens the contents of the intestines and facilitates bowel movements;
• molasses - a derivative of partial acid hydrolysis of starch with emulsifying and thickening qualities;
• sucrose - gives the drug a pleasant taste;
• volatile mint oil - a component with high fungicidal activity;
• natural flavors.

Undevit does not contain minerals and amino acid compounds. This is an exclusively vitamin preparation. It does not have a pronounced therapeutic effect, but its components are necessary for the flow of "background" physiological processes.

Pharmacological properties

The positive effect of the drug on the body is due to the biochemical properties of its constituent components. Retinol stimulates the development and proliferation of epithelial cells, promotes the synthesis of rhodopsin, the main light-sensitive pigment of the visual apparatus.

Vitamin A is needed in the body for the growth of cartilage and bone fibers. Thiamine hydrochloride serves as a natural catalyst for carbohydrate metabolism and improves the functions of the nervous system. Vitamin B1 and its metabolic derivatives are involved in the oxidative decarboxylation of alpha-ketaglutaric and pyruvic acids.

It is involved in the production of lipid compounds and belongs to water-soluble vitamins that do not accumulate in tissues and do not have toxicity. The pharmacological properties of pyridoxine are based on the stimulation of amino acid metabolism.

Undevit - vitamins (reviews note that the drug does not give a pronounced clinical effect) with a multidisciplinary physiological effect on the body. It contains pyridoxine stimulates the production of neurotransmitters and increases histamine activity.

Riboflavin contributes to the saturation of tissues of internal organs with oxygen and improves cellular respiration. Cyanocobalamin is involved in physiological processes in the hemostatic system. Vitamin B12 intensifies the synthesis of myelin, a special protein that forms the electrically insulating sheath of nerve fibers.

Nicotinamide is involved in tissue respiration, carbohydrate and lipid metabolism. It carries protons during redox reactions.

Ascorbic acid:

• participates in the synthesis of hemoglobin;
• enhances the production of corticosteroid hormones;
• promotes collagen maturation;
• improves the secretion of dentin - hard dental tissue;
• responsible for the multiplication of red blood cells;
• increases blood clotting.

Vitamin C enhances the body's nonspecific immune resistance and, together with rutin, reduces the permeability of the vascular walls. Folic acid, which is part of Undevit, ensures the normal passage of nucleic, amino acid and choline metabolisms.

Tocopherol activates protein synthesis and has antioxidant properties. It prevents the oxidation and breakdown of physiologically active substances in the body, including the components of the multivitamin complex. Calcium pantothenate creates favorable conditions for the synthesis of coenzymes - important cellular coenzymes.

Pharmacodynamics and pharmacokinetics

The multidisciplinary multivitamin complex improves the course of basic processes and reactions in the body, increases the overall resistance to bacterial and viral infections. The active substances of Undevit stimulate the production of enzymes, hormones and essential biochemical compounds.

The drug increases vitality in the elderly and patients weakened by prolonged pathological processes. It improves the metabolism of glycoproteins, which play an important role in the formation of epithelial tissues and the development of their barrier properties.

B vitamins are especially useful for inflammation of nerve tissues and degenerative diseases of the vestibular apparatus. These physiologically active components of the drug increase blood circulation, regulate the acid-base balance and intensify the elimination of toxins.

Folic acid, which is part of Undevit, has weak pharmacodynamic properties. It serves as a precursor to numerous coenzymes involved in oxygen transport and carbon evacuation. Cyanocobalamin methylates homocestine and methionine, amino acids necessary for the synthesis of nucleotides.

The pharmacokinetic properties of the drug are determined by the biochemical characteristics of its components. The ability of retinol to be deposited in the liver and, in an ether-bound modification, is known to penetrate into Culfer's cells - special macrophages that serve as part of the reticuloendothelial mechanism.

Vitamin A is released in small portions into the blood plasma. It is carried by specific globulins that interfere with the globular filtration of a physiologically active element. Retinol is metabolized into carbon dioxide and lipid compounds.

Vitamin A is not found in uric acid. Thiamine is absorbed primarily into the small intestine. It is evenly distributed in soft tissues. About 1 mg of Vitamin B1 is metabolized daily in the body.

The phosphorylation process is carried out in:

• liver;
• a heart;
• cerebral organ;
• kidneys;
• spleen.

Systemic clearance of transformed thiamine occurs in liver cells. Vitamin B1 and its metabolic derivatives are excreted by the urinary tract. The half-life is 9-18 days.

After oral administration, riboflavin easily overcomes the enterological barrier of the small intestine, penetrating into the systemic circulation. Vitamin B2 is deposited in the hepatic and renal organs.

No more than 9% of the dose taken is found in uric acid. Nicotinamide is rapidly absorbed into the gastrointestinal tract and is evenly distributed in the tissues of the digestive system.

It is metabolized in the kidneys and excreted through the urinary ducts. Pyridoxine hydrochloride, which is part of the therapeutic and prophylactic drug, has similar pharmacokinetic characteristics.

Undevit contains ascorbic acid, which circulates in the hematological fluid and concentrates in the glandular tissues. Vitamins of groups B and C are found in lymphocytes and platelets. The responses of the host states that the regular use of the medication reduces the susceptibility to seasonal diseases.

The bioavailability of cyanocobalamin is 90%. When taken in high doses, it is absorbed into the mucous membrane of the gastrointestinal tract by diffusion. The main organ of vitamin B12 deposition is the liver.

A certain amount of the substance accumulates in the spleen, kidneys, and muscle fibers. Cyanocobalamin is characterized by an extremely slow metabolism. In the liver, it is found even 12 months after the completion of the course.

No more than 0.3% of the total volume of cyanocobalamin in the body is excreted in the gallbladder. In the digestive system, the bulk of vitamin B12 circulates according to the enterohepatic principle.

The maximum concentration of Rutin, which is part of the drug, is reached after 9 hours. after oral administration. Eliminated unchanged mostly through the biliary tract, to a lesser extent through the urinary canals.

Tocopherol is absorbed into the upper gastrointestinal tract, penetrating into the bloodstream and lymphatic structures. Enters into biochemical interaction with beta-lipoprotein compounds. About 80% of an oral dose taken within a week is eliminated in feces, the rest in urine.

Indications for use

The drug is taken with hypovitaminosis, after suffering a serious illness to support the body and accelerate the recovery process.

Among the indications for use are:

• vitamin deficiency;
• normalization of metabolism;
• neurological disorders;
• the period of the formation of the body in children;
• intensive development in adolescence.

Undevit is prescribed for elderly patients to improve sleep function, relieve irritability and anxiety. The drug is part of the complex therapy of various pathologies of a chronic nature and infectious genesis.

The multivitamin complex does not provide a quick and tangible therapeutic effect, but enhances the action of others medicines, since it creates optimal biochemical and physiological conditions in the body for treatment.

With the help of vitamins, the harmful effects of antibiotics are neutralized. A multifunctional medication is prescribed to speed up postoperative rehabilitation. Undevit increases stress resistance. It makes sense to take it after severe injuries, fractures and sprains of the tendons.

The medicine improves the appetite in children and the digestive function in the elderly. It is advisable to take the medication during pregnancy (starting from the 2nd trimester) and breastfeeding, but only after prior consultation with a gynecologist or pediatrician.

Undevit - vitamins, reviews of which demonstrate the confidence of most patients in this inexpensive but useful drug. The drug is often taken as a preventive measure, with excessive mental and physical exertion, an unbalanced or inadequate diet.

Contraindications

The multivitamin complex is not prescribed in case of increased sensitivity to its constituent components.

Of the absolute clinical restrictions on use, the following stand out:

• hypervitaminosis;
• acute inflammation of the skin;
• nephritis;
• heart failure II and III degrees;
• I trimester of pregnancy;
• chronic liver dysfunction;
• infectious lesions of the urinary tract.

Thiamine should not be taken for nephrolithiasis - a urological disease associated with the deposition of calculi in the kidneys.

It is undesirable to use neurological B vitamins for:

• thromboembolism - acute blockage of blood vessels;
• erythremia - chronic leukemia;
• erythrocytosis - a pathological condition associated with an increased concentration of red blood cells and hemoglobin in the blood;
• malignant hyperplasia.

Nicotinamide is not prescribed for patients with high blood pressure and active internal bleeding.

At what age can the drug be used?

Undevit is prescribed for adolescents from the age of 14. The duration of the course and the frequency of the appointment are calculated individually by the doctor.

Instructions for use, dosage

Undevit is taken orally after meals. To replenish the vitamin reserve, the recommended dose is 1 tablet a day. With heavy physical exertion, emotional and intellectual overstrain, after a cold, the daily rate can be increased by 2-3 times.

To speed up postoperative rehabilitation, to support the body during a seasonal epidemic and in old age, it is recommended to take Undevit by the course method for 20-30 days.

The break between courses should be at least 4-12 weeks. The recommended dose and frequency of use is valid for both adults and adolescents. During pregnancy, Undevit is taken from the 2nd trimester, 1 tablet per day. With intensive therapy and as part of complex treatment, it is allowed to take 2 pills per 1 dose 2-3 times a day.

Side effects

Undevit - vitamins, reviews of which say that they are capable of provoking anaphylactic reactions of an immediate type. In patients with biological hypersensitivity and congenital tendency to allergic manifestations, angioedema, urticaria, bronchospasm are possible.

Vitamins of groups A, B and C are capable of causing:

• dyspeptic disorders;
• nausea;
• pain in the epigastric cavity;
• belching;
• vomiting;
• diarrhea.

Such side symptoms are rarely recorded. In some patients, increased synthesis of gastric juice was observed after taking Undevit. The nervous system can react to the components of the medicinal composition with migraine, dizziness, decreased muscle tone. Occasionally there is increased sweating.

Elderly patients have had:

• short-term visual impairment;
• an increase in platelet cells in the blood;
• hyperprothrombinemia;
• neutrophilic leukocytosis.

If side effects appear, the drug should be discontinued and a biocompatible analogue should be selected together with a doctor.

Overdose

When using Undevit in the recommended amounts, signs of drug intoxication are not observed.

Uncontrolled use of the drug can lead to the development of hypervitaminosis, which is characterized by the following symptoms:

• pathological drowsiness;
• periodic muscle cramps;
• general lethargy and apathy;
• nausea;
• hyperemia of the face;
• unreasonable irritability;
• vestibular disorders;
• joint pain;
• aching legs;

With such signs of an overdose, symptomatic therapy is performed, the stomach is washed, or an absorbent drug is taken.

special instructions

With the course use of Undevit, it is possible to change the color of urine, which is explained by the presence of Riboflavin in the multivitamin complex. During the entire period of treatment with medication, it is necessary to adhere to a protein diet.

This will ensure proper assimilation and exchange of vitamin components, especially water-soluble ones. The drug should be taken with extreme caution and under medical supervision in patients with peptic ulcers and toxic liver damage, including alcoholic ones.

In acute chronic nephritis, perforation of the duodenum and decompensated heart failure, it is advisable to stop taking vitamins.

In a reduced dosage, Undevit should be taken in patients with:

• impaired rheological properties of blood;
• thrombophlebitis;
• atherosclerosis;
• insulin-dependent diabetes mellitus;
• pathological conditions associated with a high concentration of glucose in the blood.

Before taking shock therapeutic doses, consultation with a specialized specialist is required. Undevit does not affect the reaction rate, psychomotor skills and the ability to drive vehicles.

Drug interactions

Retinol and tocopherol enhance each other's pharmacological properties, since they are synergistic. Vitamin A reduces the anti-inflammatory activity of glucocorticosteroid hormones.

Undevit cannot be combined with other similar drugs. Prohibited the parallel use of a multivitamin complex with cholestyramine and nitrate-containing drugs, which suspend the absorption of retinol.

Iron-saturated drugs suppress the pharmacodynamic characteristics of tocopherol. You can not combine Undevit with medicines, which include silver ions and alkaline components - trisamine, sodium bicarbonate.

The multivitamin complex should not be combined with indirect anticoagulants. Ascorbic acid enhances the action and increases the toxic properties of sulfonamides, as well as penicillin antibiotics.

It reduces the effectiveness of Heparin and accelerates the absorption of iron into the systemic circulation. It is forbidden to take Undevit in parallel with the use of oral contraceptives, the effect of which is slowed down by vitamin C.

Pyridoxine weakens the pharmacological properties of drugs for Parkinson's disease based on carbidopa and levodopa. Thiamine affects the polarization response of the nerve-muscle synapses and reduces the effectiveness of other drugs with similar activity.

Analogs

In case of biological incompatibility, Undevit can be replaced by a variety of multivitamin complexes with a similar component composition and identical therapeutic properties.

The most popular and closest analogs in price:

• Kvadevit. In addition to vitamins of all groups, it contains trace elements and amino acids.
• Revit. Enriched with retinol, thiamine, riboflavin, ascorbic acid. In terms of composition, it is slightly inferior to Undevit.
• Complivit. In addition to vitamins, it contains iron and mineral compounds.
• Elevit. The most complete complex of vitamins, micro- and macroelements, amino acids and minerals in the domestic pharmaceutical market.
• Prenatal. Multivitamin complex for pregnant and lactating mothers.

All presented medicines have different therapeutic dosages, frequency of application and duration of the course. Consult your doctor before use.

Terms, conditions of sale and storage

No prescription is required to purchase Undevit. The shelf life of the multivitamin complex is 12 months. The drug should be stored in a dry place, out of reach of children and the sun's ultraviolet radiation, at temperatures up to + 25 ° C.

Price

The therapeutic and prophylactic drug Undevit costs about 60 rubles in the capital's pharmacies. In the regions, vitamins can be bought a little cheaper. Reviews of the medication emphasize the safety of its use, but they note that one should not expect a noticeable clinical effect from the pills.

Video about the drug

Indications and overview of UndeVita: