Drotaverin during pregnancy 1-2-3 trimester, in the early, late stages. What are injections prescribed for?

Drotaverine is a drug, used during the 3rd trimester of pregnancy as a treatment for various pathologies associated with spasmodic disorders.

Forms of release and composition of the drug

This drug is produced in Russia in the form of a solution for intramuscular or intravenous injections. Drotaverine hydrochloride acts as the main substance.

Additional composition:

• sodium disulfite;
• ethanol;
• injection water.

The medicine is poured into ampoules, packaged in cardboard containers.

Pharmacological properties

The tool belongs to the group of antispasmodic drugs with a myotropic effect. The main component is similar to another substance - papaverine. However, it has a higher therapeutic efficacy and duration of action.

The active substance has a positive effect on spasms, which have a different nature of origin - muscle or neurogenic.

The action of the drug is aimed at relaxing the smooth muscle tissue located in the area of ​​the bile ducts, urinary system, as well as in the area of ​​the gastrointestinal tract. Thanks to this action, microcirculation is restored and improved, which leads to the supply of blood to the organs.

Indications for the use of Drotaverin injections during pregnancy

Drotaverin during pregnancy (3 trimester requires careful preliminary diagnosis before use injections) is prescribed for spasms of smooth muscles, the development of which is due to various pathologies.

Indications:

• cholecystitis, including complications of the disease;
• headaches;
• risks of miscarriage or premature birth;
• bowel irritation, including flatulence;
• colitis;
• pain in the lower abdomen;
• dyskinesia of the biliary system;
• dysmenorrhea;
• spasms in the cervical region;
• decreased uterine tone or hypertonicity of the uterus.

The drug during childbearing can also be used as a preparation before carrying out diagnostic procedures.

Contraindications for pregnant women

The drug has some limitations associated with the course of pregnancy or the influence of active ingredients.

Contraindications:

• intolerance to the composition;
• failure of the kidneys, liver and heart;
• 2nd and 3rd degree AV block;
• period of breastfeeding;
• prenatal condition.

With extreme caution, the medication is used for severe atherosclerosis, glaucoma, and also with reduced pressure.

Does the medicine harm the fetus in the 1-3 trimester of pregnancy?

The injection solution does not have a teratogenic or other negative effect on the course of pregnancy and the formation of the fetus, therefore it can be used at any period of gestation. However, the prescribing of the drug in this period of time should be dealt with by the attending specialist, taking into account the possible risks and expected benefits.

Instructions for use, dosage in the early and late stages

The dosage is calculated according to the established violation and the gestational age.

Thus, in the early stages, 40-80 mg of the drug is prescribed intravenously. The solution is injected slowly over 30 seconds.

In the later stages, the dosage is 40 to 240 mg intravenously. In this case, it is necessary to divide the dose into 2-3 equal doses. The drug is administered intravenously.

The duration of the course is set individually and is usually 7-14 days.

Side effects of injections

Drotaverine is usually well tolerated. However, the development of negative reactions associated with the course of pregnancy is occasionally possible, especially in the 3rd trimester.

Side effects:

• Disorders from the central nervous system: migraines; the development of dizziness; sleep disturbance (insomnia).
• Cardiovascular disorders: lowering blood pressure; feeling of palpitations; violation of heart rhythms; tachycardia; collapse.
• Digestive disorders: nausea; constipation.
• Local manifestations: reactions in the area of ​​administration of the agent.
• Allergic signs: rashes; itching; hives; angioedema; anaphylactic reactions.

If side effects occur, including signs not specified, it is necessary to cancel the further use of the medication and consult a specialist for advice.

Overdose

If the indicated dosages are exceeded, a negative effect may develop.

Overdose:

• disruptions in the conduction of the heart (ventricular and atrial);
• decrease in myocardial excitability;
• heart failure;
• respiratory depression. Including paralysis.

If signs of an overdose develop, you should immediately contact your doctor for the appointment of symptomatic therapy.

Special instructions for pregnant women

When the drug is injected, the patient should be in a horizontal position, which will avoid the development of collapse.

In the 1st trimester, the drug is prescribed for hypertonicity of the walls of the uterus. In the absence of timely treatment, the violation can lead to spontaneous miscarriage. In the early stages, the drug is recommended to be taken in pill form. Starting from the 2nd trimester, injection is used.

It is recommended to refuse to drive a car or carry out other work requiring high psychomotor reactions.

Analogs

Drotaverin during pregnancy (the 3rd trimester requires careful use of the drug) is used only if the components are well tolerated. With the development of hypersensitivity reactions, the solution should be replaced with another similar drug.

Analogs:

• No-Shpa. This drug is manufactured in Hungary as an oral tablet or injectable solution. The active substance of the agent is drotaverine hydrochloride. Indications: spasms of smooth muscles in the gastrointestinal tract, urinary system and biliary tract; headaches; pain during menstruation. Also, the drug can be used when carrying a child in order to avoid spontaneous abortion and a decrease in the tone of the uterus. Dosing regimen: 1-2 capsules from 2 to 3 times a day. The daily dosage should not exceed 6 tablets. The duration of therapy is determined individually. Contraindications: failure of the kidneys, liver and heart; breastfeeding; intolerance to the composition; children under 6 years of age; lack of lactase, galactose intolerance, glucose-galactose malabsorption syndrome. Terms of sale - no prescription. The cost of packaging in regional and regional pharmacies in Russia ranges from 50 to 480 rubles.
• Papaverine. This medication is produced in Russia in the form of tablets for oral use, rectal suppositories or an injection solution. The active substance is papaverine hydrochloride. The drug belongs to the class of antihypertensive and antispasmodic drugs. List of indications: spasms developing in the area of ​​smooth muscles of the abdominal cavity, brain, heart; auxiliary therapy for premedication. The remedy is also used during the carrying of a child with hypertonicity of the uterus and to reduce the risks of spontaneous abortion. Contraindications: AV block; intolerance to the components; elderly patients; children under 6 years of age; liver failure. Dosing regimen (for solution): 10-20 mg once. The number of applications per day is determined by the attending specialist. The duration of the course is individual. The method of sale is without a prescription. The cost of a medicine in pharmacies in Moscow and the Moscow region ranges from 40 to 250 rubles.
• Duspatalin. This medicine is produced in France as an oral tablet. Mebeverine hydrochloride acts as the main substance. The drug has a myotropic and antispasmodic effect. Indications: spasms in the gastrointestinal tract; colic in the intestines or gallbladder; irritable bowel syndrome; disorders in the gastrointestinal tract, which are accompanied by pain. The tablets can also be used during pregnancy with the development of pain in the lower abdomen and the development of spasms in smooth muscle muscles. However, treatment should only take place under the supervision of a treating specialist. Dosage regimen: taken half an hour before meals, 0.2 g 2 times a day. The duration of the course is individual. A contraindication to the appointment of capsules is intolerance to the components that make up them. The way of implementation is without a prescription. The cost of the drug in state and commercial pharmacies in Russia ranges from 460 to 615 rubles.

Drotaverine during pregnancy (the 3rd trimester requires careful observation by a specialist when taking the drug) should be replaced similar medicines only by the attending physician, taking into account the condition of the pregnant woman and the degree of tolerance of the drug funds.

Terms, conditions of sale and storage

• Store ampoules in a dry and clean place at a temperature not exceeding 25 ⁰C.
• The shelf life of the solution is 3 years from the date of manufacture.

  

• Do not use the medication after the expiry date expired on the package.
• The way of implementation is without a prescription.

Price

The drug has a different cost, which depends on the area of ​​its sale. The price is also influenced by the retail pharmacy chain that sells the drug.

You can find out the exact price of a medicine at any pharmacy located in your place of residence.

Region, region	Dosage form / dosage	Price
Moscow, Moscow region	Solution, 20 ml / 2 ml	RUB 27-140
St. Petersburg	Solution, 20 ml / 2 ml	RUB 42-84
Saint Petersburg (suburbs)	Tablets, 40 mg	12-132 rub.
Leningrad region	Tablets, 80 mg	RUB 48-127
Novgorod region	Solution, 20 ml / 2 ml	55-90 rubles

Before using the injection solution during pregnancy, including the 3rd trimester, you should consult your doctor and carefully study the instructions for use of Drotaverin. Additionally, it is recommended to read the reviews of patients who used this tool.

Video about the drug

Instructions for Drotaverinum for pain and during pregnancy: