Cyanocobalamin (Cyanocobalamin) in ampoules. Price, instructions for use, reviews

Cyanocobalamin is one from representatives of B vitamins, namely vitamin B₁₂.

The product is available in ampoules and is considered one of the most important components for maintaining normal metabolism, improving the functioning of the hematopoietic system and stimulating recovery nerve tissues. The price of the medicine is affordable and each person, if necessary, can undergo a full-fledged therapeutic course.

Forms of release and composition of the drug

The drug is available to patients in the form of a solution for parenteral administration, namely intramuscular infusion. The solution is transparent, has a bright pink-red color. There is no sediment or foreign inclusions at the bottom of the ampoules. The solution is packaged in transparent 1 ml ampoules, which are placed in special cardboard boxes of 10 pieces.

Detailed instructions are attached to the ampoules. Which describes all the rules for using the medicine and possible complications if the instructions are violated. The product contains cyanocobalamin as the main active substance.

An additional component is sodium chloride and water for injection. There are no other substances in the composition, which makes the one-component medication relatively safe for patients. Sodium chloride and water for injection do not have medicinal properties, but are present in the composition to preserve the chemical formula.

Pharmacological properties

Cyanocobalamin in ampoules (the price of the drug is affordable for each patient) has pronounced angioprotective and metabolic properties, which makes it possible to use it to improve the condition in case of metabolic disorders and blood systems.

The drug also has stimulating and regenerating properties, helps to improve the functioning of the nervous system, and prevents brain disorders. The medicine also promotes the formation of red blood cells, therefore it has an anti-anemic effect on the body.

The complex effect on internal organs and systems helps to improve the condition in case of neurological pathologies, disorders of the blood system, as well as other disorders.

Pharmacodynamics and pharmacokinetics

After the introduction of the drug intramuscularly, its active component spreads through the systemic circulation and has a therapeutic effect. Cyanocobalamin improves the formation of red blood cells, which contributes to the normal supply of oxygen and nutrients to the tissues.

Against the background of the use of the agent, there is an improvement in the process of gluing platelets, which has a beneficial effect on the condition of patients with a tendency to bleeding. As a result, a clot forms in the area of ​​vascular damage, which prevents the re-development of bleeding.

The drug also has other properties:

• The medication has a beneficial effect on the vascular wall, makes it elastic, and prevents damage as a result of thinning of the muscle layer.
• It activates metabolic processes, promotes better digestion and distribution of proteins, fats and carbohydrates in the body. Against the background of this process, tissue nutrition and the absorption of nutrients in the digestive tract are improved.
• Stimulates the accumulation of hemoglobin in red blood cells, which helps to increase its level in the blood and improves overall health.
• When used in high doses, it increases the activity of prothrombin, which has a beneficial effect on the condition of patients suffering from anemia and other blood diseases.
• Improves the functioning of the red bone marrow, which is responsible for the formation of blood cells. Against the background of stimulating the formation of cells, it improves the composition of the blood.
• Promotes liver cell renewal. As a result, it improves digestion, accelerates the process of removing toxins and harmful compounds from the body.
• Reduces the level of harmful cholesterol in the blood, which has a positive effect on the condition of patients with atherosclerotic vascular changes.

After intramuscular administration, the active component of the drug rapidly spreads through the systemic circulation and has a therapeutic effect. It accumulates in small amounts in tissues, but large doses are found in the liver after a long course.

Ingredients are absorbed in the small intestine, the drug is rapidly processed in the body and excreted by the kidneys within 1 day. Pharmacokinetic characteristics may differ from patient to patient.

In case of damage to the digestive tract, a slowdown in the processing of the ingredient is observed, in the case of diagnosing pathologies of the urinary system, there is a slowdown in the excretion of components from organism. In severe kidney disease, there is an accumulation of substances in the tissues.

Indications for use

Cyanocobalamin is used for a variety of disorders.

The drug in ampoules has an affordable price, as well as a long list of indications:

• Lack of cyanocobalamin in the body.
• Anemia of various forms and degrees of neglect. In severe cases, the drug is prescribed in combination with other drugs. Most often, the solution is indicated when diagnosing iron deficiency and folate deficiency anemia, as well as a condition provoked by a lack of certain vitamins.
• Cerebral palsy in patients of different ages, especially in children.
• Damage to motor neurons with the development of disorders of the musculoskeletal system.
• Neuralgia and neuritis. At the same time, the remedy effectively fights diseases of the trigeminal and facial nerve.
• Acute sciatica. In this case, the medicine is always combined with other B vitamins to increase its effectiveness.
• Diagnosis of multiple sclerosis at the initial and progressive stages.
• Dystrophy in patients of different ages.
• Pathologies of the red bone marrow, characterized by a violation of the formation of blood cells.
• Lesion of peripheral vessels against the background of endarteritis, diabetes mellitus.
• Revealing Down syndrome in a child.
• Liver pathologies of inflammatory and other origin. With cirrhosis of the liver, hepatitis, the drug is included in the course of therapy, which helps to increase its effectiveness.
• Dermatological pathologies of a chronic form with regular exacerbations. The remedy is effective for eczema and psoriasis, but only as an auxiliary method of treatment.

As part of complex therapy, the drug can be used for certain diseases of the heart, pancreas and blood vessels, as well as in the case of diagnosing cerebral disorders.

Contraindications

The tool is contraindicated in patients with individual intolerance to the components of the composition or a tendency to allergic manifestations. If in the past the patient has taken similar medications and has developed negative reactions, you should not use the medication without a preliminary examination.

There are other obstacles to prescribing a medicinal solution:

• Erythremia of various forms.
• Thromboembolism with severe vascular disorders. With a tendency to thrombosis, the drug is not used, as the risk of complications increases.
• Severe angina pectoris with severe manifestations and frequent attacks.
• Acute pathologies of the stomach and intestines. After the elimination of severe symptoms, it is allowed to use the medication.
• Diagnosis of erythrocytosis, that is, an increased level of red blood cells in the blood.
• Varicose veins, accompanied by thrombophlebitis. In this case, the aggravation of the condition and the intensive formation of blood clots in the vessels of the lower extremities are possible.
• Thrombosis of the coronary vessels.
• Aneurysm of large vessels.
• Severe form of renal failure, when the functioning of the organ is significantly impaired.

During lactation, the remedy is not contraindicated, but during pregnancy you should not use it without a doctor's prescription. Usually, when carrying, patients are shown funds that contain several vitamins, and their amount does not exceed the permissible daily rate.

At what age can the drug be used?

Cyanocobalamin in ampoules (the price of the product may differ in different regions) is usually used for children over 2 years old. However, the official instruction indicates that there is no age limit.

When used for children under 2 years of age, prior consultation with a pediatrician and examination is required to make sure that there are no contraindications.

Instructions for use, dosage

Depending on the specific disease, the drug use regimen and dosage differ. That is why it is impossible to use the product at home without examination.

The solution is usually administered intramuscularly, but subcutaneous and intravenous administration is sometimes allowed. 1 ml of the product contains 0.2 or 0.5 mg of the active substance, therefore, when separating the required dose, you should pay attention to this indicator.

Disease	Dosage and duration of the course
Anemia of various forms in adults	With such violations, the patient is injected with 100 μg of the drug 3 times a week. Therapy lasts from 3 to 6 weeks, depending on the severity of the pathology.
Diagnosing anemia in children	Children receive 40 mcg of the drug daily for 2 weeks. If necessary, the course can be repeated in 2-3 months.
Liver abnormalities such as cirrhosis or hepatitis	For such diseases, the daily dosage of the drug is 100 mcg, and the treatment lasts 30 days. The introduction of the medication is carried out daily.
Neurological Disorders in Adults with Central or Peripheral Nervous System Disorders	The daily dosage of the drug is determined individually and can be 200-400 mcg. The introduction is carried out every other day within a month. In the absence of a therapeutic effect, it is allowed to repeat the course after 8 weeks.
Nervous system pathologies in children	A single dosage for the patient is 30 μg, while the treatment is carried out for 4 weeks with daily administration of the drug.
Multiple sclerosis of various forms and severity	The course of therapy lasts 30 days. In this case, the patient receives 200 mcg in the first few days, after which the dosage is increased to 500 mcg.
Angiopathy on the background of diabetes mellitus, endarteritis	Such patients receive 100 mcg daily for a month. The courses are repeated 2 to 4 times a year, depending on the severity of the condition.

During treatment, it is important not to exceed the recommended dosage, and also not to prolong the course. For pathologies of the spinal column with nerve damage, the agent can be injected directly into the affected area. Moreover, it is combined with hormonal and pain relieving medications. Such a blockade is indicated for adults with severe pain and impaired mobility.

Side effects

Cyanocobalamin in ampoules (the price of the product depends on the number of ampoules in the package) can provoke complications if the instructions are violated.

Most often, they affect internal organs and systems:

• From the side of the nervous system, headache and dizziness may occur. The condition is aggravated by weakness, fatigue and sleep disturbance. Sometimes side reactions are manifested in the form of apathy, depressive disorders.
• Severe violations are manifested from the digestive tract. Patients report poor appetite, upset stools, and nausea. Some people report repeated vomiting and pain in the stomach, which occurs on an empty stomach or after eating.
• From the side of the heart, tachycardia is observed, a change in blood pressure indicators is possible, an aggravation of the course of chronic diseases.
• An allergic reaction with intolerance to the component of the composition manifests itself acutely, accompanied by severe itching, burning and peeling of the skin, the appearance of a rash on the limbs and trunk. Sometimes the rash spreads to the face.

If complications occur, it is important to immediately stop using the product and visit a doctor. In each case, the degree of their severity may differ depending on the duration of treatment and the organism of a particular patient.

Overdose

In case of an overdose, an aggravation of allergic manifestations is usually observed, but other complications may develop.

In some patients, peripheral vascular thrombosis develops, which leads to impaired circulation in the affected area and a deterioration in tissue nutrition. With prolonged persistence of symptoms, trophic changes are noted on the part of the skin of the limbs.

One of the dangerous manifestations of an overdose is pulmonary edema, which leads to suffocation, can provoke death in the absence of therapy. Often, an overdose is accompanied by the development of urticaria or Quincke's edema.

These conditions also threaten the patient's life, accompanied by severe allergic manifestations and swelling of the mucous membranes of the throat. As a result, the risk of death increases, therefore, when the first signs of an overdose appear, it is important to immediately stop using the medication and call a doctor.

There is no specific antidote to the remedy, so the treatment regimen depends on the specific manifestations. Usually, the patient receives help in a hospital setting, where his condition returns to normal within a few days.

special instructions

Cyanocobalamin in ampoules (the price of the medication may differ depending on the dosage of the main component in 1 ml of solution) can be used in combination with other B vitamins. During treatment, specialists insist on constant monitoring of blood counts. If there is an increase in platelet levels and a critical increase in red blood cells, therapy should be discontinued.

Within a few days, the indicators should normalize, for this a repeated blood test is prescribed. Use during pregnancy requires constant monitoring by a specialist, since B vitamins can have a teratogenic effect on the fetus if used in large quantities.

With intramuscular injection, pain is almost always present at the injection site. With constant injection in one place, there is a risk of a painful lump or even an abscess, so it is important to inject into different areas and constantly monitor the state of soft fabrics.

Drug interactions

You should not combine the medicine with the use of medicines containing the same active ingredient in the composition. It is impossible to combine the agent with thiamine, pyridoxine and riboflavin in the same syringe, since there is a risk of complications in the injection area.

When used in combination with antibiotics, there is a deterioration in the absorption of cyanocobalamin in the body. Do not use the solution at the same time as drugs that affect blood clotting.

Allowed to use with nootropic, sedatives, tranquilizers, as well as medicines that improve cerebral circulation.

Analogs

There are no one-component substitutes for the product that contain the same component.

However, on pharmacy shelves you can find combination medicines that contain not only cyanocobalamin, but also some other vitamins:

• Neurobion - a product based on pyridoxine, thiamine and cyanocobalamin, which is available in tablet and injectable form. It has pronounced properties, it is prescribed for neurological disorders and in order to prevent the deficiency of components in the body. Tablets are taken orally, 1 piece per day, the solution is administered intramuscularly, 1 ampoule per day. The course of therapy lasts up to 2 weeks, if necessary, it is extended or repeated after a break.
• Neurovitan - oral tablets that contain several B vitamins, including cyanocobalamin. The remedy is prescribed for vitamin deficiency and as part of the complex treatment of neurological diseases. The drug is considered effective, is used in short and long courses, depending on the purpose of the intake.

Analogues cannot be considered full-fledged substitutes, since they also contain other components, the use of which is not always required. That is why only a doctor should prescribe treatment.

Terms, conditions of sale and storage

The drug is dispensed in pharmacies with a prescription from a doctor. The maximum storage time is 2 years.

During storage, it is important to exclude direct sunlight from the solution, and also to monitor the temperature in the room, which should not exceed 20⁰WITH. The date of manufacture of the drug is indicated on the package, use after the expiration date is categorically contraindicated.

Price

The medication costs about 30-60 rubles. The price may differ in different pharmacies and regions.

Cyanocobalamin is a popular and effective ampoule that is considered very effective and helps to eliminate the symptoms of many diseases. The price of the medication is affordable, it is prescribed for neurological pathologies, liver damage and disorders of the blood system. When used correctly, the risk of adverse reactions is minimized.

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