Trialgin. Indications for use, instructions, price, reviews

Trialgin - anesthetic drug, which is actively used in the treatment of various types of pain and other symptoms that develop against the background of pathologies of internal organs. Indications for the use of a medicinal product are determined only by a doctor on the basis of the patient's diagnosis. Despite its high efficiency, the medication can provoke complications.

Release form and composition of the drug

The medication is sold in the form of tablets for oral use. They are small, white, cream or almost white in color, round in shape. The medicine is packaged in plastic plates or polymer bottles.

The plate may contain 10 tablets, in a small cardboard box there are 2 or 3 blisters and a description that indicates the nuances of use, possible contraindications for the patient. There are also packs of 100 tablets. The bottle contains 20 tablets. It is also placed in a cardboard box in which the instructions can be found.

The product contains 3 active substances with therapeutic properties:

• metamizole sodium;
• caffeine;
• phenobarbital.

Due to the combination of components, a complex effect on the body is carried out.

Tablet medication contains auxiliary ingredients:

• Talc.
• Starch.
• Magnesium stearate.
• Lactose.

Additional substances have no medicinal properties. The amount of metamizole per 1 tablet is 300 mg, caffeine - 50 mg, phenobarbital - 10 mg.

On pharmacy shelves, you can find a powder in the form of a powder, which is used to obtain a solution for ingestion.. It has an orange aroma and taste and is packaged in single-use bags of 5 g each. The bags are placed in cardboard boxes of 5 or 10 pieces. The composition of the powder does not differ from the composition of the tablet.

Pharmacological properties

Trialgin (indications for the use of the medication suggest the identification of the cause of pain and other symptoms) has analgesic properties, but also helps to reduce body temperature and improves general condition in various pathologies.

The remedy weakens the symptoms of colds, prevents the development of complications, normalizes body temperature in case of fever. Additionally, the drug has mild sedative properties due to the content of phenobarbital, despite the presence of caffeine in the composition.

The complex effect on the body leads to an improvement in the condition, especially in combination with other drugs used to treat a particular disorder.

Pharmacodynamics and pharmacokinetics

After the drug enters the digestive tract, its active components are absorbed in the small intestine, enter the bloodstream and spread throughout the body, providing a therapeutic effect.

Metamizole sodium belongs to the group of non-steroidal anti-inflammatory components, that is, it has pronounced analgesic and antipyretic properties. An additional property of the substance is the ability to block components that provoke the inflammatory process. As a result, there is a significant improvement after the first intake of a single therapeutic dose.

The properties of the product are enhanced by the presence of other components:

• Caffeine possesses psychostimulating properties, despite the presence of phenobarbital in the composition. After taking the drug, it stimulates the nervous system, and after a while, a slight sedative effect is observed. Caffeine promotes vasodilation, improves microcirculation in tissues. The substance also stimulates the work of the myocardium, kidneys, eliminates weakness and fatigue, which is often present in diseases of inflammatory origin.
• Small dosescaffeine in the composition do not have a significant effect on the central nervous system, do not provoke increased excitability and concomitant deviations.
• Phenobarbital activates the work of the respiratory center, at the same time suppresses the activity of some parts of the central nervous system. This provides a light sedative effect that helps to normalize sleep disturbed by colds and other pathologies. There is a slight suppression of the activity of the cardiovascular system, a decrease in heart rate, which reduces the load on the organs.

The presence of phenobarbital in the composition provides relaxation of the smooth muscles of the digestive tract, which somewhat weakens the negative reactions from the intestines and stomach. The low content of the component provides moderate sedation.

After oral administration, the active ingredients are rapidly absorbed into the bloodstream. Their maximum concentration is reached 1 hour after taking a single therapeutic dosage.

The bioavailability of the drug is approximately 90%, which is considered a high indicator. The distribution of components throughout the body occurs quickly, but the substances almost do not accumulate in the blood and tissues, which somewhat reduces the risk of overdose.

Ingredients are processed in the liver where they are broken down into metabolites. Metamizole crosses the placental barrier and passes into breast milk. The binding of each component to plasma proteins is different. Metamizole and caffeine bind well to proteins, phenobarbital only by 50%.

After the processing of substances, their excretion is carried out with the help of the kidneys. The period of cleansing the body differs depending on the characteristics of the organism of each patient. On average, 1-2 days are enough for the complete elimination of the ingredients. In elderly patients, pharmacokinetic processes slow down, the residual concentration of components in the blood and tissues slightly increases.

Indications for use

Trialgin is prescribed for various disorders accompanied by inflammation, pain, fever.

The main indications for the use of the drug:

• An increase in body temperature of unspecified origin. The drug is used in short courses until the cause of the symptom is identified.
• Colds and viral diseases, accompanied by fever, pain and inflammation.
• Discomfort in the lower abdomen during menstruation. In such disorders, the drug is rarely used.
• Toothache of varying intensity. The medicine is also prescribed in short courses, since prolonged use can provoke an aggravation of symptoms.
• Headache due to stress, colds, neurological disorders.
• Osteochondrosis in the acute stage, accompanied by severe pain in the spinal column.
• Arthritis and arthrosis in the acute stage. With such diseases, the patient develops severe pain in the area of ​​the affected joints, therefore, in combination with complex therapy, agents with a combined composition are shown.
• Acute sciatica.
• Neuralgia and neuritis on the background of chronic neurological pathologies. The primary onset of symptoms also involves the administration of drugs with analgesic properties.
• Pain in muscles, joints against the background of colds, viral pathologies.

The drug can be used during the recovery period after suffering injuries to the joints, bone tissue. Sometimes the medicine is indicated as part of the complex treatment of arterial hypertension in order to reduce indicators with a critical increase.

Contraindications

The medicine is not used when detecting intolerance to any of its components, a tendency to such reactions.

There is a long list of other contraindications:

• The period of childbearing and breastfeeding. Since some components of the composition pass into breast milk, the drug should not be used during these periods.
• Acute viral liver damage, liver failure, liver cirrhosis and other severe organ pathologies.
• Disruption of the red bone marrow, accompanied by a disorder of the process of hematopoiesis.
• Renal failure, acute glomerulonephritis or severe chronic course of a similar disease.
• Rehabilitation of a patient after undergoing surgery on the abdominal organs.
• Acute myocardial infarction.
• Violation of cerebral circulation in the acute stage.
• Alcohol or drug addiction. In case of alcohol intoxication, the drug is also not recommended for use.
• Myasthenia gravis of various forms and severity.
• Exacerbation of peptic ulcer of the digestive tract. The drug is allowed to be taken after the elimination of acute manifestations.
• Gastritis with increased acidity of gastric juice, frequent heartburn.
• Repeated vomiting during the day, arising from various reasons. The medicine in this case will not help eliminate the symptoms, which is due to the inability to absorb the components in the digestive tract.

For elderly patients suffering from cardiovascular pathologies, the drug is prescribed with caution. With glaucoma, epilepsy, pills are taken only after consulting a doctor.

At what age can the drug be used?

Trialgin (indications for use are indicated in the instructions for the drug) can only be taken by patients over 18 years of age. At an earlier age, use is not allowed, even if symptoms are detected that require treatment with similar drugs.

Instructions for use, dosage

The drug is intended only for oral administration in a dosage determined by a doctor. The standard regimen assumes taking 1 tablet at a time for 5 days. Moreover, during the day, the norm for an adult should not exceed 4 tablets.

Patients with any diseases of the digestive tract, liver or kidneys are not recommended to take more than 3 tablets per day. Between the doses, approximately equal intervals of time should be done, which will ensure a constant concentration of substances in the blood throughout the entire period of treatment.

Longer courses are not recommended due to the increased risk of developing complications from the digestive system. The powder is also used according to the standard scheme, that is, within 5 days and no more than 3 bags per day. For various violations, the scheme can be changed according to individual indications.

For headaches, migraines

In the case of a diagnosis of migraine, headache, the remedy can be used according to the standard scheme. However, in most cases, experts recommend taking the drug only when symptoms appear.

Most patients confirm that 2 tablets per day are enough to eliminate pain and normalize the condition. The treatment also lasts no more than 5 consecutive days. If the drug is used only when pain appears, it is allowed to take the medicine from 2 to 8 days a month, but not in a row, but at intervals of 3-7 days.

Doctors do not recommend using the drug on an ongoing basis. It is important to first identify the cause of the pain, eliminate it.

For toothache

When diagnosing toothache, the drug can be taken no longer than 2 days in a row. This is associated with an increased risk of complications from

With a cold

Viral diseases and colds usually occur with an increase in body temperature, pain throughout the body. To eliminate symptoms, it is recommended to use a powder to obtain a solution.

The daily dosage does not exceed 3 packets, but they are taken at approximately equal time intervals, previously pouring 120-150 ml of hot water. It is allowed to add sugar or honey to the solution to improve the taste. Therapy with the remedy lasts no more than 5 days.

If there is no effect, it is not prolonged. Other drugs with more pronounced properties are selected for the patient.

For stomach pain

Trialgin (indications for use suggest a preliminary examination to identify the cause disorders) for abdominal pain is used only when it is associated with the progression pancreatitis. If the cause of the pain is not identified, and the patient's condition is rapidly deteriorating, immediate medical attention is required.

It is strictly forbidden to take any antispasmodic pain relievers on your own.

They can blur the clinical picture, which will complicate the diagnosis and lead to the development of severe complications that threaten the patient's life. In case of pain against the background of exacerbation of pancreatitis, tablets are taken no longer than 5 days in a row and in a dosage not exceeding 4 pieces per day. Treatment must be approved by a specialist.

At high pressure

Despite the fact that the remedy dilates blood vessels somewhat, it does not help to significantly reduce blood pressure indicators. It can be used only as an auxiliary method of therapy in case of a critical increase in blood pressure.

In this case, the doctor prescribes antihypertensive drugs, and in case of severe headache, he can prescribe short courses of 2-3 days with a daily intake of 1 tablet in the morning and evening.

For pain during menstruation

Painful periods can bother women of all ages. To eliminate the manifestations, it is allowed to take 2-3 tablets per day at regular intervals.

Usually it takes no more than 3 days of application.

As with other disorders, the maximum duration of a therapeutic course does not exceed 5 days. It is better to agree on the use of tablets with a doctor in advance and make sure that there are no contraindications.

Side effects

During therapy, patients may experience negative reactions, even if all recommendations are followed. Complications affect the work of internal organs and systems, can manifest themselves in an acute or subacute form.

Damage area	Most common reactions
Digestive tract	The drug often leads to pain in the stomach and intestines, upset stools and impaired digestion of food. Patients report nausea, bouts of vomiting, and impaired appetite. Against the background of diarrhea and frequent vomiting, dehydration develops, which can provoke other complications and requires immediate specialist assistance.
Nervous system	From the side of the nervous system, complications also occur quite often. They are accompanied by weakness, drowsiness and depression. Often, the use of tablets leads to excessive anxiety, increased reflexes, convulsions, especially in patients with a tendency to such disorders.
Heart and blood vessels	Tachycardia and arrhythmia occur frequently during treatment. In most cases, this is due to the presence in the patient's history of chronic diseases of this system. The manifestations disappear after refusal of therapy.
Genitourinary system	Increased urination, pain in the bladder area and some other disorders are observed with the use of pills. In some patients, there is a decrease or increase in libido, depending on the individual characteristics of the body.
Respiratory system	Respiratory organs rarely suffer during treatment, mainly in patients who have a history of pathologies of this system. Sometimes shortness of breath occurs, especially with exertion, a feeling of shortness of breath.
Skin and mucous membranes	An allergic reaction to pills manifests itself in the form of a skin rash, burning sensation and irritation. Patients are worried about swelling of the mucous membranes of the eyes, nasal passages, oral cavity. Lacrimation, spread of the rash to large areas of the skin, increased itching is possible. When scratching the affected areas, the outer layer of the skin is damaged, which can lead to infection.

If negative reactions appear, you should stop using the medication and visit a doctor. You can not take other drugs for therapy on your own or ignore the symptoms.

Overdose

Trialgin (indications for the use of the drug are not a reason for taking it without consulting a doctor) provoke an overdose with prolonged use of high doses or a single use of a large amount tablets.

In this case, the general condition deteriorates significantly, there is nausea and repeated vomiting during the day, diarrhea. Experts note that an overdose develops quite rarely, since the medicine is used in short courses.

Despite this, when symptoms of an overdose appear, you should immediately stop using the drug and visit a doctor. In a hospital setting, the patient's stomach is washed, after which therapy is prescribed depending on the symptoms.

special instructions

If after 2 days of therapy with the drug there is no therapeutic effect, you should stop using it and consult a doctor.. In this case, the doctor selects another remedy that suits the patient.

When using the powder, it is important not to exceed the one-time rate and duration of the course, especially in the case of a history of chronic pathologies of the digestive tract. Taking pills also requires adherence to all recommendations. It is strictly forbidden to adjust the dose or duration of the course yourself.

Drug interactions

The drug is not used simultaneously with medicines that contain the same active substances in the composition.

Do not prescribe medication in combination with the following:

• Sedatives.
• Barbiturates.
• Caffeine-based products.
• Non-steroidal anti-inflammatory drugs.
• Cytostatics.
• Some antihistamines.
• Antiepileptic drugs.
• Muscle relaxants.

If the simultaneous use of funds from one of the groups is required, the doctor individually selects the scheme and duration of treatment, as well as dosages.

Analogs

The tool has analogues that can be used if it is not available in pharmacies or if it is impossible to prescribe for various reasons.

Most popular substitutes:

• Pentalgin also belongs to combined agents and has analgesic, antipyretic, analgesic properties. The product contains caffeine and other components, among which drotaverine can be distinguished, which has an antispasmodic effect. The drug is prescribed quite often and in short courses, the dosage is selected individually.
• Tempalgin possesses analgesic properties and can be used for pain of varying severity arising against the background of various disorders. The medicine is considered effective, contains metamizole sodium as the main substance, and is available in tablet form.

There are many more analogs with similar properties, but the doctor selects them individually in each case.

Terms, conditions of sale and storage

Dispensing of medication from pharmacies is carried out without presenting a prescription from a doctor. When storing it, it is worth preventing the ingress of sunlight and moisture. The maximum storage time is 3 years. The date of manufacture is indicated on the packaging.

Price

You can buy a tablet preparation for 120-300 rubles. depending on its quantity in the package.

Trialgin is an effective anti-inflammatory and analgesic drug that is actively used for various diseasesaccompanied by pain and fever. Indications for use require preliminary examination to identify the specific cause of pain.

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