Suprax Solutab is a quality drug that is used in therapy pathologies of inflammatory origin. 400 mg tablets are considered a good way to stop the progression of the inflammatory process. The price of the medication is high, it may differ in different pharmacies and regions. Despite this, the medication is often prescribed because of its effectiveness.
Record content:
- 1 Forms of release and composition of the drug
- 2 Pharmacological properties
- 3 Pharmacodynamics and pharmacokinetics
- 4 Indications for use
- 5 Contraindications
- 6 At what age can the drug be used?
- 7 Instructions for use, dosage
- 8 Side effects
- 9 Overdose
- 10 special instructions
- 11 Drug interactions
- 12 Analogs
- 13 Terms, conditions of sale and storage
- 14 Price in pharmacies in Moscow, St. Petersburg, regions
- 15 Video about the drug Suprax Solutab
Forms of release and composition of the drug
The medication can be purchased at the pharmacy in the form of dispersible, that is, water-soluble tablets for oral administration. The medicine is packaged in blisters of 7 pieces. The platinum is in a cardboard box with instructions for use.
The tablets are small and oblong in shape, as well as a light orange color. When dissolved, you can clearly smell the strawberry. As the main active component in the drug, there is a substance cefixime, which belongs to the group of 3 generation cephalosporins, has several pharmacological properties.
In addition, the composition contains auxiliary ingredients:
- silica;
- povidone;
- cellulose;
- hyprolosis;
- flavoring and dye.
Each tablet contains 400 mg of the active ingredient. The product is manufactured by an Italian pharmaceutical company.
Pharmacological properties
Suprax Solutab 400 mg - tablets, the price of which is quite high. They have several pronounced pharmacological properties. Since the active ingredient belongs to the group of 3 generation cephalosporins, the agent has a wide spectrum of antimicrobial activity.
Cefixime helps to destroy the most common microorganisms that provoke inflammatory diseases of the internal organs. A feature of the component is the ability to droop through the blood-brain barrier, which allows the use of Suprax Solutab in the treatment of pathologies of the central and peripheral nervous system.
The substance acts on pathogenic microorganisms, leads to a stop of their growth and reproduction. Gradually, the number of bacteria decreases, the focus of inflammation is completely cleared. As a result, not only the progression of the disease is stopped, but also the prevention of the development of complications as a result of the spread of microorganisms to healthy tissues.
Additionally, the agent helps to destroy microbes not only in the area of inflammation, but also in other organs and tissues. Pathogenic bacteria are not able to quickly develop resistance to the active ingredient of the drug, which allows it to be reused if necessary.
Pharmacodynamics and pharmacokinetics
After the penetration of the main active substance into the digestive tract, its active absorption into the systemic circulation begins. The active substance spreads throughout the body and is concentrated in the nervous tissue, organs of the respiratory system. In addition, a large amount of the drug is found in the area of the ear apparatus, as well as the genitourinary system.
The active substance quickly destroys pathogenic bacteria by suppressing their vital activity when exposed to membranes. As a result, there is a decrease in their number, up to complete destruction.
The condition of the tissues improves, the local temperature decreases, which leads to the elimination of severe symptoms. As a result, the progression of the disease stops.
It is worth noting that the active substance of the drug belongs to semi-synthetic components, but quite well and quickly absorbed in the digestive tract, reducing the negative effect on the intestines, namely the amount of beneficial bacteria. The risk of dysbiosis is reduced several times, which is also considered an advantage.
The active ingredient accumulates in small amounts in tissues and binds well to blood plasma proteins. The bioavailability of cefixime is quite high, its maximum concentration in the blood is detected within 2 hours.
The product is removed within 1-2 days. Its main amount is almost not processed in the internal organs, excretion is carried out through the kidneys and unchanged.
In patients who suffer from mild liver and kidney pathologies, the period of processing and evacuation of the active ingredient is somewhat prolonged. Food intake slows down the absorption of the components of the drug, but does not weaken its effectiveness.
Indications for use
Suprax Solutab is used for various pathologies of internal organs. The 400 mg tablets are considered the most popular among patients, despite the fact that their price is high.
The main indications for the appointment:
- Diseases of the upper respiratory tract, such as laryngitis, pharyngitis, and acute tonsillitis. In this case, the drug is used not only in the acute, but also in the chronic stage, when the patient has regular relapses.
- Acute and obstructive bronchitis of varying severity.
- Focal, unilateral and bilateral pneumonia.
- Otitis media of varying severity.
- Sinusitis in acute and chronic form.
- Infectious and acute inflammatory pathologies of the urinary tract, for example, pyelonephritis, cystitis, urethritis.
- An easy course of gonorrhea in women and men.
- Shigellosis of a complicated and uncomplicated form.
In addition, the agent can be used for inflammation of the bile ducts, as well as the intestinal walls.
Contraindications
The drug is considered potent, therefore its use is not recommended in case of a tendency to allergic manifestations or intolerance to the components of the composition. Do not prescribe a remedy for severe hepatic and renal failure.
When diagnosing intestinal dysbiosis, the drug is contraindicated, since it can provoke severe complications. During pregnancy and lactation, the medication is also contraindicated, but it is sometimes used if the benefit to the mother outweighs the potential risk to the fetus.
Exacerbation of gastric ulcer and duodenal ulcer is considered a reason for refusing to use the drug.
For elderly patients, the medicine is prescribed with caution, since its absorption in the body slows down, and the concentration in the blood increases. It is categorically contraindicated to use the medicine for internal bleeding or suspicion of a similar condition, as well as when diagnosing acute colitis, enteritis.
At what age can the drug be used?
Suprax Solutab 400 mg - tablets (the price of the product differs in different pharmacies), which is allowed to be used to treat patients over 16 years old.
For children, the remedy is not recommended, since it has a rather pronounced effect, which can provoke complications. Only in some cases is the medicine indicated for children, but their body weight should not be less than 25 kg, and the daily dose should not be more than 200 mg.
Instructions for use, dosage
The daily dosage for patients over 16 years old is 400 mg. In this case, it is important that the patient's weight is at least 50 kg. It is recommended to take the medicine after preliminary dissolution in 150-200 ml of water. However, it is allowed to take the tablet inside, followed by the use of 100-200 ml of water to accelerate the dissolution.
It is allowed to take the medicine once a day, since it has pronounced therapeutic properties and does not require use every 12 hours. However, experts allow dividing the daily intake into 2 doses in order to reduce the negative effect on the digestive tract.
Reception is carried out only after meals, which also eliminates the risk of complications from the stomach and intestines. The duration of the therapeutic course depends on the disease and the degree of its neglect. With gonorrhea, it is enough to use a single dose of the drug once.For urinary tract infections, 40 mg of the drug is prescribed daily for 1 week, only in some cases a three-day course is sufficient to relieve symptoms.
With angina, therapy lasts up to 2 weeks, especially in chronic course with regular relapses. When using a medicine for the treatment of angina in children, the daily dosage may be reduced to 100 mg, but the appointment is made by the doctor after the examination.
As a rule, the course of pill therapy does not exceed 2 weeks. If there is no effect from the use, a second diagnosis is carried out and another medication is prescribed.
Side effects
Side effects when using the drug can develop if the instructions are followed or violated. Usually complications affect internal organs and systems.
Organs and systems | Most common reactions |
Hematopoietic system | Most often, disorders of the hematopoietic system develop as a result of prolonged use of the drug without a doctor's prescription. Patients can develop thrombocytopenia, which leads to bleeding even with minimal skin damage. In addition, in the study of blood, a sharp decrease in the level of granulocytes is noted. |
Nervous system | Headache and dizziness are the most common side effects when taking the pill. Patients may experience insomnia, severe weakness, and apathy. In some patients, therapy can provoke a depressive state, the symptoms of which disappear only a few days after the end of the course of therapy. |
Digestive tract | From the side of the digestive system, complications develop most often. As a rule, patients are worried about nausea, as well as constipation. But some develop frequent loose stools, pain in the abdomen, cramps, and flatulence. Sometimes taking an antibiotic is accompanied by a deterioration or complete lack of appetite, weight loss, subject to long-term treatment. |
urinary system | Usually, the symptoms from the organs of the urinary system are mild, but in some cases, pain during urination may occur, as well as discomfort in the lower abdomen. Only sometimes, against the background of antibiotic therapy, acute nephritis develops. |
Skin | An allergic reaction occurs quite often, since the active ingredient is semi-synthetic. The reaction manifests itself almost immediately after taking the drug, characterized by a small rash that spreads to the body, limbs, and sometimes the face. Itching of the skin joins the rash, but it is mild if the patient does not exceed the recommended dosage. |
Typically, the patient is dominated by systemic symptoms. All side reactions rarely occur at the same time.
Overdose
Suprax Solutab 400 mg - tablets (the price may differ depending on the region of distribution), which rarely provoke an overdose if the patient strictly follows the instructions. However, with the uncontrolled intake of a large dose of the medication, there is an aggravation of all adverse reactions, as well as the addition of new symptoms.
Nausea accompanies the patient constantly, provokes frequent vomiting, as well as the inability to eat food and liquids. In this case, it is possible to add signs of dehydration in the form of dry mouth, weakness and impaired consciousness. Quite often, vomiting is supplemented by loose stools, which only aggravates the patient's condition.
Overdose headaches resemble migraines, are not relieved by analgesics and significantly worsen the patient's condition. In addition, the development of severe drowsiness, weakness is possible. The patient adheres to bed rest. If such symptoms appear, you should immediately stop taking the drug and visit a doctor.
As a rule, in the hospital, the patient is prescribed antihistamines, glucocorticoids, but the gastric lavage procedure is performed first.
special instructions
The product should not be taken on its own. It is recommended to pre-visit a doctor and undergo an examination in order to clarify the diagnosis. Usually, the doctor prescribes a clinical blood test, as a result of which abnormalities indicating the development of an inflammatory process can be detected.
In most cases, with sinusitis, the remedy brings a good result, but it is not prescribed so often. With frequent relapses of pathologies of the middle and inner ear, but you should not use it every time, since the risk of developing resistance to this type of cephalosporins in microorganisms increases.
Reviews of patients and specialists about the action of the drug are predominantly positive, which proves its effectiveness. In the case of use for the treatment of cystitis, a positive result is observed after a few days, and relapses are rare. Experts draw the attention of patients to the fact that the combination of an antibiotic with alcohol can lead to negative reactions.
Drug interactions
Suprax Solutab 400 mg - tablets, the price of which is justified. They should not be combined with other medicines belonging to the cephalosporin group. This can lead to complications and also increase the likelihood of microbes developing resistance.It is allowed to take an antibiotic in combination with non-steroidal anti-inflammatory, analgesic and antispasmodic drugs. Simultaneous administration with antihistamines and hormonal drugs is allowed.
If the agent is prescribed in combination with diuretic medicines, it is worth considering a slowdown in the elimination of cefixime from the body, which does not affect the therapeutic effect. Experts strongly discourage the use of an antibiotic with antacids, which slow down absorption from the digestive tract.
Analogs
In some cases, the use of the original medication is impossible for various reasons.
There are substitutes for drugs that have similar therapeutic properties:
- Panzef - a drug from the group of 3 generation cephalosporins, which contains the same active ingredient as Suprax. The medicine is available on pharmacy shelves in the form of tablets and granules for the preparation of oral suspension. The scheme of therapy with the agent is determined individually. Usually tablets are prescribed to adults, and granules are used to treat children.
- Ceforal Solutab is an absolute analogue of Suprax in composition and therapeutic properties. The medicine is also available in the form of water-soluble tablets for oral administration, applied according to the scheme, which involves the use of 400 mg per day for 5-14 days, depending on the severity of the condition sick. The drug is not recommended to be used on its own, it is better to consult a doctor first.
- Cefix - one of the most popular analogs, which is used to treat adults and children of different ages. The drug is available in the form of capsules of various dosages and granules for the preparation of a suspension. The second form of release is usually used to treat children under 12 years of age. The tool is highly effective and is prescribed in courses of 3-9 days, depending on the degree of neglect of the disease.
Any of the analogs helps to eliminate the symptoms of the disease, but it is allowed to use it only after examination.
Terms, conditions of sale and storage
The medication can be purchased at the pharmacy after presenting a prescription from a doctor. It must be stored in a cool, dark place, it is important to protect it from children and sunlight. The maximum shelf life is 3 years.
Price in pharmacies in Moscow, St. Petersburg, regions
The cost of a medicine in pharmacies in St. Petersburg and Moscow is approximately 750-800 rubles. In the regions, you can buy a medicine for 680-700 rubles.
Suprax Solutab - popular and very effective tablets, the price of which corresponds to the quality. Usually, patients are prescribed a dose of 400 mg, which allows them to improve the condition in a few days and prevent complications. The appointment is made by the doctor after the examination.
Video about the drug Suprax Solutab
Review of the antibiotic Suprax Solutab: