Azithromycin children. Instructions for use of the tablet, suspension, capsule. Price, analogues, reviews

Azithromycin - a semisynthetic antibiotic, featuring a wide range of antibacterial action. The drug used in the treatment of childhood infectious diseases. According to the instructions for use of low toxicity, well absorbed by the body and has a short course of treatment.

The chemical composition and trade names of the drug

Azithromycin is a domestic antibiotic erythromycin derivatives, and relates to the third generation of bactericidal drugs. The main element - azithromycin monohydrate.

Depending on the form in his release drug added additional components:

• Refined saccharose or in powder form;
• Anhydrous trisodium phosphate;
• colloidal silica (anhydrous);
• calcium hydrogenphosphate;
• corn starch;
• gelatin;
• magnesium stearate;
• E951 sweetener;
• flavors (mint, strawberry, apple);
• stabilizers (E415, E463, E171).

The drug is known as a main component, as the substance is an active component of the drug analogs, these include:

• Azivok.
• Azimitsin.
• AzitRus.
• Zitrolid.
• Zimaks.
• GI factor.
• Suitroks.
• Sumamed.
• Sumazid.
• Hemomitsin.

These drugs belong to a common group of azithromycin and are easily interchanged.

When you select should pay attention to the constituent components, as they can cause an allergic reaction.

release Form

Azithromycin is sold in pharmacies in various forms, so it is possible to select, based on the age and condition of the child.

Types of release of the drug:

dosage form	Characteristic	The amount of active substance (mg) 1st dose
Pills	In the shell or lozenge.	125 250 500 1000
Powder	The granules were yellow-creamy. Sold in bottles. To use is necessary to add the right amount of water. Included with the powder are measuring syringe or spoon. The suspension has a sweet taste and a pleasant aroma.	100 200
capsules	One half of orange and one white capsule. Inside gelatinous mass with the active substance.	250 500
lyophilisate	Frozen powder for injection.	500

The injections are used to treat seriously ill patients. In childhood, the lyophilisate is not used. Pediatrician chosen a suitable form of the antibiotic, and is assigned to a single dose of treatment. Self increase or decrease the amount of preparation will not give the desired effect of the treatment.

Operating principle

Azithromycin child (using instruction contains information about the action of the drug on the body), is fast for treating an infection which reduces healing time. After the use of the means the maximum quantity of active material is noted after 120-180 min.

Complete excretion occurs within 6 days after receiving (In the faeces and 5% in the urine). The last dose of the drug is in the body of another 6-7 days. And all this time retained a therapeutic effect means. Therefore, the treatment is sufficient, a single administration of the drug per day, and the course of treatment is 3-5 days.

The acidic environment of the stomach does not affect the efficacy of the drug, but the food can slow down the action. Azithromycin is localized in the inflammatory locus (tissue, lung, skin), drug concentration in the blood is minimal. Therefore, the antibiotic does not cause severe harm to the body, and acts only on the infection.

Due to the direct effects, a means is highly effective. The active element does not allow bacteria to grow and multiply, and violates their viability. The antibiotic has no effect on fungi and viruses.

Indications

Azithromycin is indicated for infectious diseases caused by bacteria which are sensitive to the basic component.

The drug used in the treatment of:

1. ENT disease (sinusitis, otitis media, tonsillitis).

   

2. Inflammatory processes in the lung (bronchitis, pneumonia).
3. Infections in the digestive tract (stomach and intestinal ulcers).
4. bacterial skin lesions (impetigo, erysipelas, acne).
5. Diseases of the genitourinary system (urethritis, cervicitis).

The pediatrician may prescribe an antibiotic, the development of complications of colds if penicillin funds were powerless to infection. The drug used in the treatment. Often assigned in general treatment of complications of viral diseases, for avoiding adherence of a bacterial infection.

At what age is allowed to take

Depending on the form of preparation varies the patient's age. The suspension of powder is allowed to receive from 6 months. Capsules and tablets 3 years. Since children under can suppress drug. Injections with azithromycin can be placed after 16 years. For young children (under 3 years), a single dose is calculated from the weight of the child's pediatrician.

Contraindications

Azithromycin children (instruction manual contains a clause - contraindications, which is required for the inspection) are not always allowed to use. At the age of 6 months, the drug is not administered.

And it can not be used in diseases:

• severe liver disease and kidney. If the functioning of the slightly broken, the dosage calculation is calculated pediatrician;
• intolerant elements are part of the drug;
• diseases of the cardiovascular system followed by an arrhythmia;
• diabetes and other endocrine disorders.

When the drug is contraindicated in the child, the pediatrician selected analogue. Self-replacement drug is prohibited.

Side effects

When using the drug in a child may experience side effects that are listed below in descending order of probability of their occurrence.

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1. Disruption of the functioning of the digestive tract (diarrhea, abdominal pain, nausea).
2. Headaches with dizziness.
   
3. The deterioration of hearing health and vision (tinnitus, conjunctivitis).
4. Skin rash, accompanied by itching.
5. worsening of sleep.
6. Increase in heart rate and pain in the chest area.
7. Reduced hepatic and renal function, with probability of pathology.
8. Changing the composition of the blood.
9. Stomatitis and candidiasis due to changes in the microflora.
10. Inadequate behavior.

In bright manifestation of these symptoms it is recommended to choose an analogue of azithromycin. Violation of the chair, flatulence, and abdominal pain are present when taking any antibiotic, so it is a symptom not a cause of the replacement drug.

Instructions for use

Azithromycin children need to give your child based not only on the instructions for use. Pediatrician selects the dosage and rate according to the severity and type of disease, and also takes into account the weight of the child and medicines used together. Usually used for day one single dose, the treatment duration is from 3 to 5 days.

The drug can be given over 1 hour before a meal or after 2 hours after meals, but not on an empty stomach.

Otherwise, the absorption of azithromycin will be longer. Taking the medicine must be washed down with warm water. Moreover, if the child is given suspension, the powder is recommended to dilute in boiled water at room temperature. The prepared solution should be shaken before each use.

If you accidentally pass the drug, it should be taken at once, and the next batch of the drug taken within 24 hours. When receiving the capsules and tablets for better efficacy of the drug, they are not recommended to chew and crack.

The dosage tablets

Tablets produced with different contents of active substance, for ease of use. Pediatrician calculated single dose per 1 kg of weight 10 mg drug is taken. From the result obtained for tablets appointed 125,250,500 or 1000 mg of active substance.

Next the drug can be assigned depending on the disease the child:

1. Colds or upper respiratory tract disease. A single dose is used 1 time per day for 3 days.
   
2. Skin diseases. The first day is given the second dose, the next day of the 4-D for the first dose. The course is 5-five days.
3. Inflammations of the urogenital system. Child is given 2 nd dose 1 times. 1 day course of treatment.
4. In diseases of the tick bite treatment uses a similar skin diseases.
5. In the treatment of ulcer formation caused by infection, the child is given 2 nd dose over 3 days.

When the child is assigned single dosage of 500 mg, the parents can give a tablet of 500 mg or 2 tablets at 250 mg. But it is not recommended to divide the tablet of 1000 mg. Similarly appointed and at a dosage of 250 mg.

When side effects can not reduce the dosage of the drug. Then the treatment has no effect, and the health of the child harm. Pediatrician picks antibiotics having a similar effect, and azithromycin canceled.

Dosage suspension 125 mg, 250 mg, 500 mg

Azithromycin children (instruction on the suspension contains information on the preparation of solutions different concentrations of active substance) for children under 3 years recommended to use in the form of powder. The convenience of this form of the drug can be accurately metered and the child it easier to use.

For this purpose the measuring spoon or syringe. To wash away the remnants of the drug from the oral suspension after the child should be given a little water or juice.

Can be prepared from powder 2 kinds of solutions contained 100 or 200 mg of active substance. When cooking in a vial is added the right amount of water (the amount specified in the instructions, as well as the marked line on the vial). It should be borne in mind that in calculating the dosage is now taken not 10 mg, and 0.5 ml per 1 kg of weight of the child.

The finished suspension was stored in a refrigerator for 5 days. Then the drug is considered unsuitable for treatment. In therapy suspension major diseases considered to tablet form, the reception unit dosage remains the same.

It is important that the baby is completely swallowed a means, not spit or burp him. If this happens, it is necessary to give the child an antibiotic again. With the resumption of regurgitation or spitting drug is given again. Please refer to the pediatrician and replace analogue means.

Overdose

Accidental overdosing the drug urgently needed gastric lavage, child fed activated carbon or polisorb. If the poisoning is not strong, then these procedures is sufficient. When a large overdose, you must call the emergency care.

As a result, increased doses of the drug at the child may occur temporary deafness. Simultaneously, may be present with diarrhea and nausea vomitus. Failure in the digestive tract can lead to dehydration, so it is necessary to give the baby more liquid if necessary, saline.

Interaction with other drugs

Antibiotics are often prescribed in conjunction with other medications. Therefore, the azithromycin may designate pediatrician only if it does not potentiate the side effects of drugs and reduces their effectiveness.

Medicines that can not be taken together:

1. Co-administration of drugs alter the acidity of the stomach reduces the digestibility of the antibiotic. This reduces its effectiveness. Upon receiving these drugs it is recommended to wait 2 hours before taking the antibiotic.
2. Not recommended simultaneous reception at once 2 or more types of antibiotics. This increases the side effects of the drugs.
3. At the same time prohibited from taking azithromycin with blood thinners.
4. Vasodilators may increase the likelihood of side effects.
5. You can not use an antibiotic treatment when combined with infusions of alcohol-based. These children are rarely appointed, but in some cases the therapy used.
6. When using both the azithromycin and immunosuppressants (used in organ transplantation), amplified by 2 nd drug that could harm the organism.
7. The combined use of antifungal agents reduces the effectiveness of the antibiotic.

If the disease is only detected and other drugs have not been taken, as well as the appointment of azithromycin is important. That other medicaments are selected in combination with an antibiotic.

When the treatment has already passed, and the antibiotic is needed to eliminate the complications of the disease, there is to inform the pediatrician on the admission of all drugs, even if the reception has stopped for 1-2 days ago. Not all drugs at once removed from the body.

Terms of sale and storage

Azithromycin in any form can be purchased in pharmacies by prescription only pediatric dose specified rate and reception. When you purchase is necessary to pay attention to the expiration date. Depending on the type of drug and the manufacturer, the expiration date can be changed.

On average, preparations are stored for 2-3 years. Suspensions after opening or preparations suitable for 5 days.

Medicines should be stored away from the baby in a dark and cool place (temperature not higher than 25 degrees). Failure to comply with the conditions, the shelf life of the drug is reduced. Desirably, this tool is not used for the treatment.

analogs

Azithromycin children (instruction manual discussed above, refers only to the drug) has a large number analogues that are similar in action, but have different compositions (for extra components), contraindications and side effects.

If necessary, the azithromycin may be replaced by the following medications:

1. azivok. It is sold in the form of gelatin capsules. Approved for the treatment of children after 12 years of age and weighing over 45 kg. Medication contraindicated with tackle liver function, kidney failure and lactose.
2. Azimitsin. Appointed in tablets and solutions for medicine droppers. Approved for use after 12 years and with a weight of over 45 kg. Side effects and contraindications similar to azithromycin.
3. AzitRus. It is a powder to prepare a slurry (6 months), the capsule (3 years) and the tablet (12 years old). At reception there is a violation in the digestive tract and the cardiovascular system. Should not be taken together with food consumption.
4. vilprafen. You can buy in the form of coated tablets for sucking (with the taste and aroma of strawberries). Used for the treatment after 14 years. Reception can cause disruption of the digestive tract, itching, and hearing loss. With poor functioning of liver and kidney, the drug is taken under the supervision of a pediatrician.
   
5. Zitrolid. This capsule (yellow-white color) and the solution for injection. Application is permitted from 12 years. The reception can cause problems with blood composition, the change in behavior and a failure of breathing. When the liver and kidney pathologies reception prohibited.
6. Zimaks. Sold in a variety of forms: tablets, capsules (with 2 x s) and suspension (6 months). In the treatment of single dose can be divided into 3 doses over the same time interval. The drug affects the liver and kidneys, can cause impaired vision and hearing.
7. GI factor. Capsules and tablets are allowed to receive a 1-year. The drug affects the kidneys, liver and heart. And also disrupts the functioning of the digestive tract (bloating, diarrhea, abdominal pain)
8. clarithromycin. This pill, which are allowed to accept after 12 years. The drug may cause malfunction of the gastrointestinal tract, the cardiovascular and nervous system.
9. macrofoams. Can be bought in the form of powder, tablets, which are approved for use with a 6-months. The course of treatment may be up to 14 days. Application can cause rashes and nausea. In case of violation of the liver and kidney taken with caution.
10. Rovamycinum. Tablets are approved for treatment after 6 years. When you receive a possible disruption of the digestive tract. When liver pathologies take supervised pediatrician.
11. roxithromycin. This pill is to be appointed after 12 years. The drug can cause a malfunction in the digestive tract, cause dizziness and allergic reactions. When the renal and hepatic pathologies there are limitations in reception.
12. Suitroks. Powder for suspension can be given to children after 6 months. Reception can cause vomiting, diarrhea, headache. In liver and kidney diseases need to control pediatrician.
13. sumamed. The suspension is allowed to 6 months, a tablet with a 3-years. The drug can cause goiter, headaches and disruption of the heart. When the renal and hepatic pathologies reception means is not recommended.
14. Sumazid. Can be bought in the form of tablets, capsules and powder for suspension. Age restrictions similar as that of azithromycin. The medicine can cause diarrhea, vomiting and itching.
15. Hemomitsin. This capsules, tablets (12 years old) and suspension (6 months). The drug can cause goiter, urticaria and dizziness.
16. erythromycin. Means are rarely assigned to 12 months, as it has many side effects. Available in syrups, suspensions, tablets. For young children, you can buy medicine in the form of candles.

These preparations can be assigned pediatrician if the side effect is not due to the primary component. Otherwise, funds are needed other kinds of antibiotics.

Price in drugstores of Moscow, St. Petersburg, regions

Azithromycin cost varies depending on the form of the drug and the amount of active substance in it. As well as the price changes from producer.

Average prices of drugs (in rubles):

Regions	Pills	capsules	Powder
Moscow	40-320	120	200
SPB	30-280	110	180
Yekaterinburg	35-310	110	190
Volgograd	30-300	105	185
Permian	32-270	110	190

The cost of the tablets are presented with a large range, as a function of concentration of active substance and the amount of tablets in the package, the price varies considerably.

Azithromycin is effective in children and low drug with a short course of therapy. In the treatment of children must be observed not only the instructions for use, but also recommendations pediatrician. Depending on weight, type of disease and the severity of the disease, the prescribed treatment can be different from that specified in the instructions.

Author of the article: Svetlana Kotlyachkova

Registration of the article: Lozinski Oleg

Video of azithromycin children

Reviewed by a doctor of azithromycin, the effectiveness and side effects: