Unidox Solutab. Analogues are cheaper, instructions for use, where to buy, price, reviews

Unidox Solutab - popular antibacterial agent, which is often prescribed to patients with inflammatory pathologies of bacterial origin. The price of the drug is quite high, so many patients are looking for cheaper analogues. However, the effectiveness of the drug fully justifies its cost, so it is better to use the original drug.

Forms of release and composition of the drug

The pharmacological agent can be purchased at pharmacies in tablet form. The tablets are small, biconvex, round, white or yellowish in color. They are packaged in special plastic blisters of 10 pieces.

Each blister is placed in individual cardboard boxes, where detailed instructions for correct use can also be found. Dispersible tablets, that is, they are used after preliminary dissolution in water, which significantly accelerates the absorption of active substances.

The drug contains doxycycline and as the main active ingredient. Due to it, the main therapeutic effect is carried out.

The tablets also contain auxiliary ingredients:

• Hyprolosis.
• Microcrystalline cellulose.
• Lactose monohydrate.
• Silicon dioxide.
• Magnesium stearate.
• Hypromellose.

Additional ingredients have no medicinal properties. The product is not available in other dosage forms.

Pharmacological properties

Unidox Solutab (analogues may contain other components in the composition cheaper) has pronounced antibacterial properties due to the content of the main active component in the composition. The tool is effective against many microbes that provoke pathologies of internal organs and systems.

It should be noted that the drug in small doses has bacteriostatic properties, in higher doses it has a bactericidal effect. The drug also helps to eliminate signs of inflammation, which often occur against the background of bacterial tissue damage.

The tool helps to reduce body temperature, an increase in which is observed as a result of the progression of the inflammatory process. As a result, a significant improvement in the condition is observed and the involvement of healthy tissues that are closely located in the pathological process is prevented.

Pharmacodynamics and pharmacokinetics

After penetration of the agent into the digestive tract, the active components are distributed through the systemic circulation. Doxycycline belongs to the antibacterial components from the tetracyclines group. It has pronounced bacteriostatic properties, helps to stop the multiplication of bacteria and disrupts metabolic processes in their membranes.

As a result of metabolic disorders in membranes, microbes die and tissues are cleansed of their waste products, which significantly improves the condition. However, it should be noted that the weakening of symptoms occurs somewhat later than when using drugs with pronounced bactericidal properties.

The activity of the active substance against gram-positive and gram-negative microorganisms is noted, which most often provoke inflammatory and purulent pathologies of internal organs.

Experts also point to the effectiveness of the drug against pathologies provoked by mycoplasmas, chlamydia and spirochetes. This is considered to be an advantage of the drug in comparison with other antibacterial drugs.

The greatest efficiency is observed in therapy with a means of pathologies provoked by streptococci and staphylococci of various types. When using the drug, there is an improvement in the condition for 5 days.

The active substance is quite well absorbed in the digestive tract, which explains the high efficiency and rapid onset of therapeutic action. The bioavailability of the drug reaches 90%, which is considered a high indicator. The drug binds well to plasma proteins.

After oral use, the ingredient is rapidly distributed throughout the body. After 2 hours, doxycycline can be detected in all fluids and tissues. The only exception is the cerebrospinal fluid, into which the agent does not penetrate.

It is due to the rapid penetration through all tissues that the drug has a pronounced effect. The active ingredient is able to penetrate the placental barrier and also passes into breast milk.

Absorption in the digestive tract is rapid. Only with disorders of the digestive system is there a slight slowdown in the absorption of substances in the small intestine. The processing of the active ingredient is carried out in the liver, and excretion in equal amounts occurs with the help of the kidneys and the large intestine.

With a single use, it is possible to detect the active substance in the blood after 19 hours. If the patient goes through the full course, doxycycline is retained in the tissues; it can be detected 2 days after taking the last dose.

The period of evacuation of the decay products of the active ingredient takes up to 3 days, depending on the state of the urinary system. With kidney damage, a slowdown in the excretion of metabolites of the active substance is observed. Despite this, the medication is considered effective, it is used for a mild course of the disorder.

Indications for use

Unidox Solutab is used for pathologies that are provoked by microbes that are sensitive to the active component of the composition. Cheap analogues can have a narrow spectrum of antimicrobial activity, therefore, they have a smaller list of indications.

The main conditions requiring the appointment of dispersible tablets:

• Hearing system pathologies, accompanied by a pronounced inflammatory process as a result of the multiplication of pathogens.
• Diseases of the mucous membranes of the goral, for example, tonsillitis, chronic and acute tonsillitis, laryngitis and pharyngitis.
• Diseases of the lower respiratory tract: acute and chronic bronchitis, tracheobronchitis, pneumonia at various stages of development. The tool helps not only to quickly eliminate the manifestations of diseases, but also prevents the development of severe complications.
• Pathologies of the urinary system in acute and chronic form. The tool effectively fights the signs of pyelonephritis, glomerulonephritis, cystitis, urethritis, prostatitis.
• Inflammatory disorders from the organs of the reproductive system, for example, endometritis of varying degrees of neglect.
• Sexually transmitted diseases are also treated with medication. With ureaplasmosis, gonorrhea, syphilis and chlamydia, it can be prescribed as the main medicine or as part of complex therapy.
• Diseases of the blood of inflammatory origin against the background of bacterial infection. With sepsis, the agent is highly effective.
• Abdominal abnormalities, such as peritonitis. The tool is not used as an independent method of therapy, but it can significantly enhance the effect of other medicines.
• Bone pathologies, accompanied by the development of a purulent process. The drug is actively used for mild and severe osteomyelitis, since a large amount of doxycycline is concentrated in the bone tissue.
• Whooping cough at various stages of development.
• Brucellosis in patients of different ages.
• Purulent lesions of soft tissues, infected trophic ulcers that occur against the background of vascular lesions, as well as advanced diabetes mellitus.

The tool can also be used during the recovery period after surgery, preventing complications that often occur when immunity is weakened.

Contraindications

The drug is contraindicated in case of intolerance to its components or detection of allergy to the main substance in the patient's history. Do not prescribe medication for severe hepatic and renal impairment.

Contraindications include the period of pregnancy and breastfeeding, since the drug penetrates into breast milk and through the placental barrier. Do not prescribe a medicine for internal bleeding that occurs against the background of ulcerative lesions of the digestive tract.

It is also worth remembering that the medication is contraindicated in patients who suffer from porphyria, since pills can significantly worsen the condition and provoke complications.

Do not prescribe a pharmaceutical agent when a severe form of angina pectoris, coronary heart disease is detected, as well as during the recovery period after myocardial infarction and ischemic stroke. The medicine can provoke complications, as well as aggravation of the course of the pathological condition.

Relative contraindications include the period of rehabilitation after fractures of the spine, extremities. It is strictly contraindicated to use it without a preliminary examination and consultation with a doctor.

 At what age can the drug be used?

Unidox Solutab (analogues may be cheaper, may be less effective) is allowed for use in the therapy of patients from 8 years of age. It should be noted that the dosage for children is selected individually and taking into account the weight.

It is forbidden to use the product for children under 8 years old, even in the absence of indications for the appointment.

Instructions for use, dosage

The agent is taken only orally at the prescribed dosage. Before use, the tablet should be crushed into powder and mixed with 100 ml of pure water. Depending on age, the dosage and duration of use is determined by a specialist.

Adults usually take 2 tablets of the medication per day. It is allowed to take the daily rate at a time or divide it into 2 doses during the day at regular intervals. The duration of the therapeutic course depends on the degree of neglect of the disease. Usually, treatment lasts 5 days, sometimes an extension of the course up to 10 days is required.

In the first 2-3 days of therapy, patients always take 2 tablets, but during the next days the specialist may reduce the dosage to 1 tablet if the patient's condition improves and a maintenance intake is required dose.

When diagnosing syphilis, gonorrhea and some other disorders, the daily dosage rises to 3 tablets. In this case, it should not be taken at once, it is better to divide it into 3 parts and consume it during the day. The treatment lasts 5 to 10 days.

For children from 8 years old with a body weight of up to 50 kg, the dosage is calculated depending on the weight. For 1 kg of body weight, there are 0.004 g of the product. A preliminary examination by a doctor and determination of the degree of neglect of the disease is required. Children also use the remedy for 5-10 days. The duration of therapy depends on the condition and the presence of concomitant complications.

Side effects

Unidox Solutab (cheaper analogs may have a less pronounced therapeutic effect) often provokes complications, even if the instructions are followed. Disorders can manifest themselves on the part of internal organs and systems.

Organs and systems	Most common disorders
Nervous system	Headache when using the medication is observed quite often. In addition, patients may be worried about weakness, fatigue and depression. Sleep disturbances with prolonged use are often observed, while patients feel tired, performance is significantly reduced.
Digestive organs	From the side of the digestive tract, complications occur most often. They manifest as nausea, bouts of vomiting, and impaired digestion. The condition is almost always accompanied by upset stools, abdominal pain, flatulence, and bloating. Therapy can provoke an exacerbation of gastric ulcer, gastritis, colitis and enteritis.
Hematopoietic system	The use of tablets can provoke disorders of the hematopoietic system. They are characterized by a change in the number of platelets and erythrocytes, as well as a deterioration in the supply of oxygen to tissues.
Genitourinary system	Disorders from the genitourinary system often occur with prolonged use of the drug in high dosages. Disorders are accompanied by pain in the kidney area, increased urination, exacerbation of chronic kidney pathologies.
Skin	An allergic reaction when using the drug can affect the skin of the body and limbs, accompanied by a rash and severe itching, in which there is irritation and peeling. The condition of patients is aggravated by constant scratching of the affected areas, and the risk of infection increases.

The severity of negative reactions depends on the body of a particular patient, as well as the duration of the drug in high doses.

Overdose

The drug can provoke an overdose, which is accompanied by severe acute disorders. Patients report severe headache, dizziness, and nausea. The condition is aggravated by repeated vomiting, dehydration, and intense thirst.

With prolonged persistence of symptoms, dryness of the mucous membranes of the oral cavity, indigestion and persistent diarrhea are observed. If the patient does not see a doctor, dehydration can provoke seizures and other disorders.

An overdose is accompanied by weakness, fatigue and a deterioration in concentration. If such disorders appear, you should immediately stop using the medication and visit a doctor.

In a hospital setting, the patient is provided with assistance, which consists in carrying out gastric lavage. After that, patients are prescribed enterosorbents and some other drugs, depending on the symptoms.

special instructions

Unidox Solutab (cheaper analogs may not be as effective in some cases) is allowed to be consumed without preliminary dissolution in water if the patient is not able to use the solution.

In some cases, the agent is used to treat acne, which is caused by the activity of microorganisms that are sensitive to the agent. Feedback from patients confirms the effectiveness and speed of action in the treatment of acne of varying degrees of neglect. In addition, the medicine can be used in conjunction with a special diet to help reduce the risk of the rash recurring.

When using an antibiotic, the simultaneous administration of lactobacilli, for example, Linex or Bifidumbacterin, is required. This will reduce the risk of developing negative bowel reactions. It is especially important to observe this rule when treating children.

Drug interactions

An antibacterial medication is not prescribed in combination with agents that contain the same or similar active ingredients. In addition, it is forbidden to use the drug simultaneously with hormonal contraceptives, as well as enterosorbents, antacids. This is due to a decrease in the effectiveness of the antibiotic.

If you need to use magnesium-containing medicines, diuretics, calcium and iron preparations, you should take a break of at least 3 hours so as not to reduce the effectiveness of the antibiotic. In each case, prior consultation with a doctor is required in order to prevent complications.

There is no development of negative reactions when the drug is combined with anti-inflammatory, antipyretic, vascular drugs.

Analogs

The tool has several analogues that can be used as a substitute and in most cases have a more affordable cost.

The most effective analogues:

• Doxycycline - the most popular analogue, which contains the same active ingredient in the composition and has the same therapeutic properties. The remedy is prescribed for various inflammatory pathologies of bacterial origin, it is indicated for adults and children from 8 years old. The dosage and duration of use is always determined individually, depending on the disease.

  

• Vibramycin Is a doxycycline-based product that is available in capsule form for oral administration. The drug has a pronounced therapeutic effect, helps to destroy most gram-positive and gram-negative bacteria, significantly improves the condition in the severe course of the pathological process. It is prescribed for adults and children from 8 years of age if indicated, the dose and duration of treatment in each case is different.

Analogs of the remedy are used only as directed by a doctor. Any of them is not prescribed for pregnant and lactating women, as it provokes severe complications. Substitutes are much cheaper, so they are often used in consultation with a specialist.

Terms, conditions of sale and storage

The drug is dispensed in different pharmacies on prescription from a doctor, which significantly complicates the acquisition, but reduces the risk of complications with uncontrolled self-administration.

The maximum storage time is 5 years. During storage, it is important to limit access to the product for children and direct sunlight. The production date is indicated on the package, use after the expiration date is not allowed.

Price

The cost of tablets starts from 350 rubles. per packing. The price may vary in different regions and pharmacies.

Unidox Solutab - effective and efficient tablets, which are often prescribed for the defeat of internal organs and systems by pathogens.

The drug has a high price, so patients often look for analogues that will be cheaper, but have the same therapeutic effect. Despite this, it is recommended to use the original medication, which will ensure maximum effectiveness.

Video about the drug

Doctor about Unidox Solutab: