Dancil is a drug used for ear pathologies. The cost of drops is in the budget segment and is affordable for most patients.
Record content:
- 1 Forms of release and composition of the drug
- 2 Pharmacological properties
- 3 Pharmacodynamics and pharmacokinetics
- 4 Indications for use
- 5 Contraindications
- 6 At what age can the drug be used?
- 7 Instructions for use, dosage
- 8 Side effects
- 9 Overdose
- 10 special instructions
- 11 Drug interactions
- 12 Analogues for children and adults
- 13 Terms, conditions of sale and storage
- 14 Price
- 15 Video about the analogue of Danzil
Forms of release and composition of the drug
It is manufactured in India as an ear-instillation solution. The active substance of the drug is ofloxacin.
Additional composition:
- benzalkonium chloride;
- disodium salt of ethylenediaminetetraacetic acid;
- hypromellose;
- caustic soda;
- sodium chloride;
- hydrochloric acid;
- injection water.
The medicine is contained in plastic dropper bottles and packed in a cardboard container.
Pharmacological properties
The drug belongs to the category of fluoroquinolones with antimicrobial and bactericidal action.
Pharmacodynamics and pharmacokinetics
The solution exhibits broad antimicrobial activity. Its bactericidal effect is due to the influence of the active component against the DNA gyrase of the pathogenic microorganism.
The drug is effective against most gram-negative microflora. In this case, the drug is also active against some gram-positive pathogens, including streptococcus and staphylococcus.
Resistance to the active component is shown by anaerobic types of bacteria.
When administered orally, the components of the agent are rapidly absorbed from the gastrointestinal tract. Eating food may slightly slow down the absorption of the drug.
The maximum concentration of drug components occurs after 2 hours. In this case, the level of protein binding is 25%.
The active substance penetrates into tissues and body fluids.
The components of the medication are excreted in an unchanged form during the day. About 4% of the drug leaves the body along with the feces. The half-life of the components is 6 hours. In elderly patients, the elimination time can be doubled.
Indications for use
Dancil - ear drops (the price of the product is available for most patients), which should be used only if there is an established diagnosis. The drip solution is used in the treatment of infectious and inflammatory diseases of the ENT organs caused by the action of pathogenic microflora.
Indications:
- otitis externa;
- chronic course of otitis media, accompanied by the formation of pus, including pathology in which there is a lesion of the tympanic membrane (perforation);
- acute course of otitis media with a previous bypass of the tympanic membrane.
The drug is used only as directed by the treating specialist.
Contraindications
The drug has some restrictions on its use associated with the patient's condition or the effect of the active substance.
Contraindications:
- hypersensitivity to the composition of drops;
- non-bacterial otitis media;
- the period of bearing and feeding the child;
- childhood.
With extreme caution, the medication can be prescribed to patients with functional impairment of the kidneys or liver.
At what age can the drug be used?
The drug is approved for use in adolescence, starting at the age of 15. In this case, therapy should be carried out under the supervision of a specialist (otolaryngologist).
Instructions for use, dosage
Dancil - ear drops (the price of the solution is not a factor affecting its therapeutic effect), which are intended only for external use.
It should be borne in mind that a cold drug can lead to the formation of dizziness. To avoid such symptoms, it is recommended to preheat the vial in your hands for 1-2 minutes.
When using the medication, it is recommended to lie on your side. After installation, it is required to maintain this position for several minutes. This is necessary for even distribution of the drug.
The dosage and course of therapy is calculated based on the established form of the disease.
With the development of otitis externa, 10 drops of the drug are prescribed in the affected ear. Instillation is carried out once a day. The duration of therapy is 1.5 weeks.
In case of acute course of otitis media with previous bypass surgery, 5 drops of the drug are prescribed 2 times a day. In this case, the duration of treatment is no more than 1.5 weeks.
With the formation of otitis media, accompanied by purulent discharge and perforation of the tympanic membrane, the dosage is 10 drops 2 times a day. The duration of the course is 2 weeks.
Side effects
In most cases, the medication is well tolerated. However, occasionally, against the background of taking the drug, it is possible to develop negative symptoms associated with the action of active ingredients or the physiological characteristics of the patient.
Side effects:
- nausea and vomiting;
- the occurrence of dizziness;
- allergic symptoms;
- mild to moderate local pain;
- redness in the area of the tympanic membrane;
- tinnitus;
- short-term hearing loss;
- development of external or otitis media.
If these symptoms occur, including unregistered symptoms, it is recommended to refuse further medication and consult a specialist for advice.
Overdose
There are no data on drug overdose. However, if the prescribed daily norms are exceeded and any negative manifestations occur, it is recommended to stop further therapy and consult with the attending specialist.
special instructions
Dancil for the treatment of ear pathologies is forbidden to be taken orally. The drip solution should only be used as directed by your healthcare professional. At the same time, the cost of the drug does not affect its pharmacological properties.
When using the drug throughout the entire period of therapy, it is necessary to undergo systematic studies of blood glucose levels. With prolonged use of the medication, it is required to undergo systematic studies of the state of the functions of the kidneys, liver and blood.
Adequate fluid intake must be observed when using the solution. It is recommended to avoid prolonged exposure to the open rays of the sun.
Drops are prohibited for use while carrying or feeding a child. Based on laboratory tests carried out on rats, the solution has no effect on human fertility.
According to research, the agent does not have a mutagenic effect. The carcinogenic properties of the drug have not been studied. According to laboratory tests on animals, the active substance of the drug led to the development of arthropathy and osteochondrosis.
There are no data on the use of the drug in childhood.
The drug can have a negative effect on the psychomotor and visual functions of a person. Therefore, during the period of application of the drip solution, it is recommended to be very careful when driving or performing work that requires high psychomotor reactions.
Drug interactions
The drip solution may react with other medications.
The effectiveness of the drug may decrease with the simultaneous use of the following drugs:
- antacids;
- sucralfate;
- products that include aluminum, magnesium or calcium;
- medicines based on 2- or 3-valet cations;
- vitamin complexes containing zinc.
It is recommended to maintain the interval before taking the funds 2 hours before or 2 hours after applying the solution.
The combination of the main drug and medicines belonging to the group of non-steroidal anti-inflammatory drugs drugs (NSAIDs), may lead to an increased risk of seizures or overstimulation of the central nervous systems.
The simultaneous administration of ear drops and theophylline can provoke an increase in the level of the second drug in the blood. At the same time, an extension of the half-life of theophylline is also noted, which leads to the risk of developing adverse drug reactions.
An additive interaction of drugs can develop against the background of the use of a solution and the following medicines:
- aminoglycosides;
- metronidazole;
- antibacterial agents belonging to the class of beta-lactam compounds.
When using other medicines, including for external treatment of ear diseases, it is recommended to inform the attending otolaryngologist about this in advance.
Analogues for children and adults
Dancil - ear drops (the price of the main product may differ significantly from substitutes), which in some cases can lead to hypersensitivity reactions. In the event of the formation of such effects, the solution should be replaced with other medicines that are similar in action and indication.
Analogs:
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Floxal. The manufacturer of this medical device is Russia. The preparation is made in the form of a solution for external use. The main ingredient in the drops is ofloxacin, an antibacterial substance that is active against most gram-negative pathogens. Also, the agent shows moderate activity against some gram-positive pathogens. A medicine is prescribed in the treatment of chronic otitis media, including the rehabilitation period associated with the treatment of the disease. Contraindications to the use of the medication are the following conditions: intolerance to the active substance (allergy to the composition), the period of gestation or feeding of the child. In pediatric practice, the solution can be used only in consultation with the attending specialist. The dosage and duration of use of drops is determined by the attending otolaryngologist, based on the established form of the disease, as well as the degree of damage. The method of sale is by prescription. The cost of a medicine in commercial and state pharmacies in Russia is from 170 rubles. for the bottle.
Floxal eye drops - Uniflox. This medication is produced in the Slovak Republic in the form of drops for external use. The active component of the agent is ofloxacin, a broad-spectrum antibiotic that exhibits high activity against most gram-negative pathogens, as well as some gram-positive bacteria. List of indications for medication: otitis externa, chronic otitis media, including pathology with perforation of the tympanic membrane. The solution can also be used in pediatric practice for acute otitis externa and otitis media with a previous bypass of the tympanic membrane. 10 drops of the drug are prescribed per day in the affected ear. Installations are carried out 2 times a day. The duration of treatment is 1.5 weeks. Contraindications: non-bacterial form of otitis media, period of gestation and feeding of the child, hypersensitivity to the composition of the drug, children under 12 months of age. Terms of sale - according to the recipe. The cost of a medicine in Moscow and regional pharmacies is from 125 rubles. per packing.
- Ofloxacin. This product is manufactured at a Russian pharmaceutical plant in the form of drops for external use. The active ingredient of the solution is ofloxacin, an antimicrobial substance belonging to the class of fluoroquinolones. The remedy is effective against most gram-negative pathogens and is used in the treatment of the following pathologies: otitis media with tympanopuction, otitis media with perforation of the tympanic membrane, prevention before or after surgery, chronic and acute otitis externa and otitis media caused by the action of bacteria. List of restrictions: intolerance to the composition, epileptic seizures, central nervous system disorders, minor age, chronic non-bacterial otitis media. The dosage is determined by the attending specialist and on average ranges from 0.2 to 0.8 g per day, depending on the pathology. The duration of the course is individual, depending on the severity of the disease. The way of selling the drug is by prescription. The cost of a bottle in Russian pharmacies starts from 150 rubles. per bottle.
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Oflo. This medicine is manufactured in India as an infusion solution. The active ingredient of the drug is ofloxacin.
It belongs to the category of antibacterial medicines with a wide spectrum of activity. The drug has high activity against most gram-negative pathogenic pathogens. Indications for the use of medication in otolaryngology: otitis media, sinusitis, tonsillitis, pharyngitis. With the development of an infectious lesion of the ENT organs, 0.2 g of solution is prescribed 2 times a day. If necessary, the dosage can be increased to 0.4 g. The duration of therapy is set by the doctor individually. List of contraindications: minor age, allergy to components, period of gestation and feeding of the child, lack of glucose in the body, disorders of the central nervous system with a low seizure threshold. Method of implementation by prescription. The cost of the solution in regional and regional pharmacies in Russia ranges from 135 to 247 rubles.
Dancil - ear drops (the price of the solution is not a criterion for choosing a similar medication), which should be replaced by other means only after prior agreement with the attending physician.
Terms, conditions of sale and storage
It is not recommended to select analogs on your own, since an incorrectly chosen remedy can lead to a worsening of the condition or cause the development of allergic reactions.
- The drug should be out of the reach of children at a temperature not exceeding 250C.
- The shelf life of the funds is 24 months from the date of manufacture. In this case, after opening the bottle, it is allowed to use drops for 1 month.
- Do not use the medicine after the expiry date of the expiry date on the package.
- Terms of sale - according to the recipe.
Price
The drip solution has a different cost depending on the area of sale and the retail pharmacy network.
| Region / region | Dosage form / volume | Price |
| Moscow, Moscow region | Drops, 0.3%, 5 ml | RUB 112-199 |
| St. Petersburg | Drops, 0.3%, 5 ml | RUB 138-234 |
| Saint Petersburg (suburbs) | Drops, 0.3%, 5 ml | 124-205 rub. |
| Novgorod region | Drops, 0.3%, 5 ml | RUB 133-214 |
| Leningrad region | Drops, 0.3%, 5 ml | RUB 142-187 |
Before using Dancil, you should carefully read the annotation for the use of ear drops. Additionally, it is recommended to consult with a pharmacist or specialist, as well as study patient reviews. You can clarify the cost, as well as purchase the drug at any commercial or state pharmacy located at the place of residence.
Video about the analogue of Danzil
Floxal drops:
