Analogue of Doxycycline (Doxycycline) in tablets, capsules, cheap, imported without prescription. Price

Doxycycline is a semi-synthetic antibacterial means in the form of tablets belonging to the pharmacological group of tetracyclines. The drug has a wide spectrum of antimicrobial action, allows for effective treatment diseases that are provoked by infectious agents resistant to antibiotics of penicillin row.

A distinctive feature of this drug is that its active substance is capable of penetrating into the infected cell of the body and destroying pathogens leading to intracellular parasitism. Analogs of the product can be purchased at retail pharmacy chains.

Form of release, composition and properties of Doxycycline

Doxycycline is produced in the form of capsules and tablets covered with a protective film. The medicine is packaged in contour blisters made of polymeric materials. Each cassette of this drug contains 10 tablets.

The main packaging of the antibiotic Doxycycline is a cardboard box, inside which there is 1 or 2 cassettes with an antibacterial agent, as well as detailed instructions for its practical use. The active component of this drug is the chemical substance doxycycline hydrochloride at a dosage of 100 mg in 1 tablet. There are analogues of this medication with an identical composition.

The antibacterial agent Doxycycline has the following pharmacological properties:

• has a pronounced bacteriostatic effect;
• penetrates into the structure of the infected cell, which allows for an effective fight against intracellular microbes and parasites;
• disrupts the cell division of most gram-positive and gram-negative bacteria, which inevitably leads to their gradual death and early recovery of the patient;
• allows you to achieve a rapid decrease in the level of pathogens;
• the therapeutic efficiency is superior to antibiotics of the tetracycline series, which have a natural etiology;
• improves the protective function of local immunity;
• promotes a more rapid reduction in the acute inflammatory process, which is caused by infectious microorganisms.

At the same time, Doxycycline tablets do not have a therapeutic effect in the treatment of diseases caused by mycoses, Pseudomonas aeruginosa, and Proteus. A distinctive feature of this antibiotic is that it does not have such a negative effect on intestinal microflora, much less often causes dysbiosis and other negative reactions from the organs Gastrointestinal tract.

Indications for use

Doxycycline analogue tablets can be purchased only on the basis of a doctor's prescription. This drug has a wide range of practical applications.

Doxycycline is used to treat the following types of diseases:

• inflammatory lesion of the pleural sheets;
• acute bronchitis of bacterial etiology;
• lobar pneumonia;
• chronic tracheitis, accompanied by periodic exacerbations of the disease;
• purulent abscess of the lung;
• kidney inflammation;
• chronic cystitis;
• infectious damage to the tissues of the prostate gland in men;
• urethritis;
• chronic tonsillitis;
• inflammation of the inner ear with signs of decreased hearing acuity, or without manifestation of this kind of symptomatology;
• dysentery of bacterial origin;
• endocervicitis;
• gonorrhea, as well as other infections of the genitourinary system, the causative agents of which are sensitive to the active component of Doxycycline;
• sinusitis and sinusitis;
• cholecystitis;
• infectious abscesses of the skin surface of the body;
• chlamydia;
• initial stage of Lyme disease;
• leptospirosis, ehrlichiosis of the granulocytic type, as well as other diseases transmitted by blood-sucking parasites;
• bacterial endocarditis;
• peritonitis;
• blood poisoning;
• cholera;
• tularemia;
• infection of thermal, chemical, electrical burns;
• osteomyelitis of bone tissue, regardless of the localization of the infectious and inflammatory process;
• chlamydial arthritis.

Doxycycline can be used in patients who have undergone surgery, and in the period of their rehabilitation remains a high risk of infection of the wound surface with bacterial microorganisms. For elderly men, this antibiotic is indicated for use in the treatment of acute prostatitis, as well as severe infections of the genitourinary organs.

Before using Doxycycline for therapeutic purposes, it is necessary to undergo a comprehensive examination, to be tested for microflora. Only after the fact of the sensitivity of infectious agents to the constituent components of the drug has been established, therapy with this antibiotic is allowed.

Contraindications

An analogue of Doxycycline in tablets is found in pharmacies in most cities in Russia.

The drug is categorically contraindicated for practical use in the presence of the following circumstances:

• porphyria;
• liver failure with severe course;
• individual lactose intolerance;
• a tendency to manifest an allergic reaction to the constituent substances of this medication;
• children's age up to 12 years (taking this antibacterial agent by younger patients can lead to a violation of the structure of the bone tissue of their musculoskeletal system);
• leukopenia and other types of diseases associated with a violation of the cellular balance in the general composition of the bloodstream;
• malignant neoplasms in the liver tissues;
• the state of pregnancy, regardless of the trimester of fetal formation (the constituent components of the antibiotic are able to penetrate the placental barrier and disrupt the development of the child's skeleton);
• breastfeeding the baby.

Doxycycline is contraindicated in children over 12 years of age who have a body weight below 45 kg. In this case, the risk of developing side effects and other negative reactions of the body increases.

Doxycycline is prescribed with extreme caution to patients who have concomitant liver tissue diseases. Taking this antibiotic can aggravate the condition of this organ, as well as provoke the development of its fatty infiltration.

Instructions for use, dosage

An analogue of Doxycycline in tablets can be prescribed by the attending physician if there is a direct medical indication.

• Adults and children over 12 years old with a body weight of more than 45 kg should take at least 200 mg of this antibiotic on the first day of therapy. The indicated dose is divided into 2 doses, observing the time interval from 8 to 10 hours. In the future, the daily dosage of Doxycycline is 100 mg of the active ingredient of the drug.
• Children and patients of the adult age group who are being treated for infectious organ diseases the genitourinary sphere, should take 200 mg of antibiotic throughout the entire period of the course therapy.
• In the treatment of syphilis and a complicated form of gonorrhea, Doxycycline tablets are taken at a dosage of 300 mg of the main substance for the next 10 days.
• Patients with signs of an infectious lesion of the mucous membrane of the rectum, cervix, inner layer of the genital organ, the urethra without signs of complications, should drink 100 mg of this medication 2 times a day at the same time. In this case, the course of treatment is at least 7 days.
• Therapy of chronic or acute prostatitis, as well as other infectious diseases of the male reproductive system, requires a daily intake of 100 mg of the drug 2 times a day for 4 weeks.
• For effective treatment of leptospirosis, you should drink 100 mg of Doxycycline 2 times a day with a course of therapy for at least 7 days. Then you will need to pass a second analysis to determine the presence or complete cleansing of the body from a pathogenic infection.
• Prevention of leptospirosis requires taking 200 mg of an antibiotic once a week for the entire period of time in an epidemiologically unfavorable region.
• Treatment of acne with signs of bacterial infection is carried out by taking 100 mg of Doxycycline 1 time per day with a course of therapy from 6 to 12 weeks, depending on the clinical picture of the disease and the dynamics of the restoration of epithelial fabrics.
• Prevention of infectious infection of the organs of the female reproductive system after an abortion requires a single dose of 100 mg of an antibiotic 1 hour before getting rid of the child, as well as 20 mg of Doxycycline after 30 min. upon completion of gynecological manipulations. Adults and children who have chronic liver diseases, severe functional disorders in the work of this organ, an individual adjustment of the therapeutic dosage is required.

The active substance of Doxycycline has the property of accumulating in the patient's body, which increases the risk of developing hepatotoxic effects with an aggravation of the patient's general condition.

Precautionary measures

To completely eliminate the factor of local irritation of the mucous membrane of the stomach and intestines, which may appear during contact with the active substance of the tablets, it is recommended to take Doxycycline directly during a meal or immediately after meal.

When taking this antibiotic, you must drink as much liquid as possible. In conditions of prolonged therapy with Doxycycline, regular monitoring of the functional state of the liver tissues is required. This will minimize the risk of developing toxic effects with the further occurrence of liver failure.

Due to its pronounced antibacterial effect, Doxycycline can temporarily mask the symptoms of syphilis. Patients suffering from this disease observe the complete disappearance of painful symptoms, but at the same time, a small amount of pathogenic infection still persists in individual tissues organism.

To comply with precautions, it is recommended not to stop the course of antibacterial treatment, as well as for 4 months. donate venous blood every 30 days for a serological test for the causative agent of syphilis. This will avoid the transition of a venereal disease into a latent form with a chronic course.

Doxycycline is a semi-synthetic antibiotic of the tetracycline series, which means that it has the property of creating stable mineral complexes with calcium molecules in the composition of human bone tissue organism.

In this regard, prolonged use of this drug can lead to staining of the surface of the teeth in yellow, brown, and gray. The manifestation of enamel hypoplasia is not excluded.

This property of Doxycycline is especially pronounced in children over 12 years of age, whose jaw apparatus continues to form. After the complete cessation of taking this antibacterial drug, the restoration of the natural color of the teeth occurs over a long period of time, but in each case, this process is individual character.

Throughout the entire period of treatment with Doxycycline, it is strictly forbidden to carry out the simultaneous administration medicines that have pharmacological properties of inhibition of natural peristalsis intestines.

During therapy with this antibiotic, it is strongly recommended to temporarily refrain from administering vehicles, as well as performing work requiring increased attention and concentration thought process.

After a sudden interruption of a long course of Doxycycline therapy, signs of diarrhea may occur, which indicates a mild degree of dysbiosis and the need to take medications based on living bacterial cultures.

Side effects and overdose

An analogue of Doxycycline in tablets is used in case of individual intolerance to this medication.

While taking this drug, the development of the following side effects is not excluded:

• increased intracranial pressure;
• nausea;
• constipation or fluid diarrhea;
• stomach ulcer;
• dizziness;
• violation of coordination of movements;
• swelling of the optic nerve;
• cramping pain inside the abdominal cavity;
• enterocolitis;
• Strong headache;
• noise in ears;
• complete lack of appetite;
• various kinds of allergic reactions;
• drop in blood pressure;
• arrhythmia;
• thrombocytopenia;
• anaphylactic shock;
• changes in the cellular composition of the blood;
• pericarditis;
• functional disorders of liver tissue;
• an increase in the concentration of urea, as well as residual nitrogen compounds;
• darkening of the enamel.

The occurrence of the above side effects of Doxycycline requires a complete cancellation of further administration of this medication. Violation of the dosing rules with this antibiotic can lead to the development of an overdose, which manifests itself the following symptoms of general intoxication of the body:

• cramps of the lower extremities;
• dizziness;
• migraine;
• nausea;
• vomit;
• toxic effects on the central nervous system;
• severe liver dysfunctions;
• diarrhea;
• lack of appetite;
• intracranial pressure.

Treatment of an overdose with Doxycycline requires multiple lavage of the stomach cavity using activated charcoal. If the drug was taken within the last 2 hours, then the patient is prescribed therapy with antacids, as well as drugs based on magnesium sulfate.

These medicines help prevent further absorption of Doxycycline into the general bloodstream. Hemodialysis is ineffective.

Domestic and imported analogues of the drug in tablets

On the pharmaceutical market, there is a wide selection of drugs in tablet form of release, which are analogs of the antibiotic Doxycycline, produced by Russian and foreign pharmacological companies.

Doxycycline hydrochloride

Doxycycline hydrochloride is a domestically produced medicinal product manufactured by the Erecton Scientific and Production Center. The active substance of this medication is doxycycline at a dosage of 100 mg.

This drug is indicated for use in the treatment of infectious diseases of the upper and lower respiratory pathways, skin surface, organs of the genitourinary system, the fight against intracellular parasitic microorganisms. Doxycycline hydrochloride comes in the form of capsules that are made from edible gelatin.

This drug has a pronounced antibacterial activity against most strains:

• Staphylococcus aureus;
• streptococcal infection;
• clostridium.

Xedocin

Xedocin is a tablet analogue of the drug Doxycycline, which is produced by the German pharmaceutical company Rottendorf Pharma. The therapeutic dosage of this medication is 100 mg. Xedocin tablets are covered with a protective film, which has a light brown color with a slight grayish tinge.

Also, this medication is available with a concentration of the active substance of 200 mg, depending on the individual needs of each patient. Xedocin is a synthetic tetracycline antibiotic used to treat infectious diseases caused by microorganisms susceptible to doxycycline. Dispensing of the medication is carried out by prescription.

Doxycycline-Ferein

Doxycycline-Ferein is an analogue of the drug Doxycycline, which is produced by the Russian pharmaceutical company PJSC Bryntsalov-A. This antibacterial agent is produced in the form of capsules, the shell of which is made of gelatin. Inside the medication there is a white powder with a dosage of the active substance of at least 200 mg.

The main package of the drug is a cardboard box, inside which there are 10 or 20 capsules. Doxycycline-Ferein is indicated for use in infectious lesions of the digestive tract, excretory and reproductive systems, blood, and lower respiratory tract. This drug is contraindicated in case of individual intolerance to tetracycline antibiotics.

Unidox Solutab

Unidox Solutab is an antibacterial agent based on doxycycline, which is produced by the domestic company ZiO-Health. The therapeutic concentration of the active substance in the composition of this medication is 100 mg.

This drug is indicated for use for the treatment of infectious diseases of the lungs, bronchi, prostate gland, uterus, kidneys, urinary canals, rectum, hematopoietic organs.

Unidox Solutab is contraindicated in patients suffering from lactose intolerance, antibiotics tetracycline series, in a state of pregnancy, as well as having functional disorders in liver function. The dispensing of this medication is carried out exclusively by prescription.

Doxycycline-Velpharm

Doxycycline-Velpharm is an analogue of domestic production, the production of which is carried out by OOO Velpharm, which specializes in the production of various kinds of medical products. This drug is a rich yellow capsule made of a gelatinous shell. The dosage of the drug Doxycycline-Velpharm is 100 mg.

This drug is effective against most gram-positive and gram-negative microorganisms, but at the same time does not show therapeutic efficacy in interactions with fungi. Doxycycline-Velpharm is contraindicated in persons prone to an allergic reaction to tetracycline, in pregnant women and with hepatitis B, in patients with severe liver disease.

Comparison of the cost of Doxycycline and its analogues

Below is a comparative table showing the average prices of the antibacterial agent Doxycycline of domestic and foreign production.

Drug name	Price
Doxycycline hydrochloride	340 RUB
Doxycycline-Velpharm	335 RUB
Xedocin	RUB 485
Unidox Solutab	342 r
Doxycycline-Ferein	650 RUB

Doxycycline is an effective broad-spectrum drug, the main form of release of which is tablets covered with a protective film. Analogs of this drug are also produced in the form of cylindrical capsules made of edible gelatin. Doxycycline belongs to the pharmacological group of semi-synthetic antibiotics of the tetracycline series.

The use of this tool allows for successful therapy of syphilis, Lyme disease, ehrlichiosis, tularemia, gonorrhea, chlamydia, infectious diseases provoked by strains of Staphylococcus aureus, streptococcus, clostridia. The release of this medication is carried out only on the basis of a doctor's prescription.

Video about Doxycycline

Doctor's opinion about the drug Doxycycline: