Kipferon candles for children. Reviews, instructions for use, analogues, price

In infancy, the protective functions of the body are imperfect, and the consequences of viral diseases are often dangerous. For help the drug Kipferon comes. According to parental reviews, candles for children help to cope with diseases, protect from complications, and increase immune defenses.

Form of release and composition of the drug Kipferon

The balanced composition of the drug allows it to be used for the treatment of both infants and adults.

Kipferon - candles for children, reviews of many parents about which are mostly positive.

The antiviral agent contains:

• KIP, complex immunoglobulin preparation, 60 mg;
• recombinant bacterial strains capable of producing interferon with a biological activity of 500 thous. IU;
• additional substances that promote the release of the active ingredient and its uniform distribution: emulsifier, fat, paraffin, sodium salts, water.

Suppositories are white, cylindrical in shape, firm to the touch. Candles, 5 pcs., Packed in special plates. The cardboard box contains instructions, as well as 1 or 2 blisters.

Pharmacological properties

Immunity of a newborn, before forming into a full-fledged immune system, undergoes several stages. During the first month, the mother's antibodies provide protection to the baby.

The next 6 months are considered the most dangerous for the baby, when the body is not able to provide full protection against infections. It is during this period that frequent relapses of diseases occur, since contacts with others increase.

And only after 7 years, the child's lymphocyte count decreases, and the levels of immunoglobulins approach the level of adults. This means that the immune system is able to protect the baby from infections. But at the same time, the level of immunoglobulin A remains low, which reduces the protective function of the mucous membrane, through which viruses penetrate.

Respiratory and intestinal infections in infancy account for 90% of all diseases. Therefore, it is considered promising to use additional funds in which immunoglobulin is involved in conjunction with ready-made human recombinant interferon.

The human body in response for the penetration of foreign agents, it produces a specific protein, interferon. It suppresses viruses, their reproduction, activates immune factors. There are two types of drugs for suppressing viral infections.

Some contain ready-made interferon, while others are its inducer. The second group of drugs is not prescribed to infants, since they are immunomodulators that can affect the fragile immune system of the child. At this age, the process of producing their own interferon in babies is poorly established.

For this reason, children at this age are offered a ready-made interferon preparation. These funds begin to fight viruses as soon as they get inside. Drops and sprays work locally, without affecting the state of the whole organism. Suppositories are more effective because the active substance enters the bloodstream faster.

Rectal administration is child-friendly:

• One candle contains the required single dose. The small shape of the candle promotes rapid absorption into the general bloodstream by the system of hemorrhoidal veins.
• The medicine enters the body immediately, bypassing the intestinal tract, therefore it acts quickly and efficiently. The rectal route of administration does not irritate the digestive tract. The main active ingredient of the drug is not exposed to hydrochloric acid, enzymes, thereby increasing the effectiveness of the action.
• The drug has no adverse reactions.

Pharmacodynamics and pharmacokinetics

Kipferon - candles for children, reviews of scientists, doctors and parents about which are positive in 95% of cases. They are classified as immunotropic drugs.

What functions are performed by the substances included in the preparation:

• Antiviral. The components of the drug affect enzymes that inhibit the growth and reproduction of viruses.
• Immunomodulatory. They activate the activity of cells that suppress pathogens.
• Anti-inflammatory. Reduces the process of inflammation.
• Antimicrobial. Capable of destroying intracellular microbes.

The drug, acting at the intracellular level, penetrates the lymph, blood, pleural, articular and intercellular fluids.

The composition of the immunoglobulin contains nonspecific and specific immunoglobulins of class A, G, M, which are still insufficient in the baby's body. They stick together, neutralize and remove cells containing various viruses into the sediment. Interferon alfa-2b is obtained from donors' whole blood tested for HIV and hepatitis.

Interferon, or a protein molecule, does not have selective antiviral activity, but acts on all viruses. Interferon, getting into the blood, binds to the receptors of antigen cells, attaching to them, triggering a certain reaction.

As a result, specific proteins are formed that protect the cell surface. It becomes impenetrable and inaccessible to viruses. Thus, interferon suppresses intracellular processes, preventing the development of viruses, chlamydia, intracellular parasites. With the help of interferon, antibacterial, antiviral protection is activated.

Pharmacokinetic studies of the drug were carried out in pregnant women with infectious inflammatory diseases. The patients received suppositories containing 500,00 IU of alpha 2b interferon. Within 4 hours, the serum concentration decreased after dosing.

In the next 4 hours, the concentration in the blood increased, which indicates the stimulation of the body's own interferon production under the influence of the drug. The total average time of the presence of interferon in the body is 7.5, and the half-life is about 5 hours. The effective effect of the drug on the body is 12 hours.

Indications for the use of candles for children

Kipferon is used in combination with other drugs to eliminate symptoms of acute or chronic inflammatory processes.

Diseases for which the drug is recommended:

• bronchitis, laryngitis, pneumonia;
• thrush;
• intestinal dysbiosis of various etiologies;
• viral hepatitis in a child;
• infection that has arisen in the postoperative period;
• bacterial infections of the genitals;
• chlamydial infections.

Contraindications

It is not used in children with intolerance to the structural components of the drug, as well as younger than 6 months.

At what age can the drug be used?

The use of Kipferon in children under 6 months of age is not recommended by doctors.

Instructions for use, dosage

Kipferon contains fat in its composition. It is designed for a more convenient introduction of children's candles, which is positively noted in parental reviews.

Drug injection procedure:

• Empty the intestines.
• Warm up the candle in your hand for 2-3 sec.
• Lay the child on one side with one leg bent.
• Insert the candle, then lightly press and hold the buttocks to prevent the candle from coming back out.

  

Drug therapy implies certain doses, which are calculated by the formula: for 1 kg of baby's weight, 50 thousand. IU. If a child has 10 kg, he needs to enter 1 candle per day.

There are restrictions:

• up to 7 years, no more than 2 doses (1,000,000 IU) are permissible;
• from 7 years to 12 - no more than 3 doses or suppositories (1,500,000 IU);
• children from 12 years old are injected with 4 candles per day.

Large doses are divided into 2 doses - morning and evening. The default course of treatment is no more than 5-10 days. Additional administration of the drug is agreed with the doctor.

Doctors identify individual treatment regimens for each disease.

In the case of pneumonia, rotaviruses, acute respiratory infections, inflammation of the nasopharynx with bacterial, viral etiology, therapy is carried out within 5 days.

• For an infant in the first year of life, 1 dose per day is recommended.
• Age period from 1 to 3 years - 2 times a day, 1 candle.

After that, suppositories are administered 2 times a week, once in the morning and once in the evening, the general course is 3 weeks. Therapy also includes the use of antibiotics.

With frequent repeated bronchitis, respiratory diseases, pneumonia, children use the drug 2 times a day during the first 4-5 days, and then treatment continues for up to 20 days, while the interval is observed every 3 day. In addition to Kipferon, antibiotics are used in the treatment.

Inflammation of the gastrointestinal tract caused by infections is recommended to be treated with the drug after a cleansing procedure with an enema.

• The dosage for children under 12 years of age is calculated based on body weight. So, 50,000 IU is taken for 1 kg, but not more than 2 candles per day. The course of treatment depends on the severity of the disorder and ranges from 5 days to 2 weeks. It is advisable to start therapy no later than the second day after the onset of the disease.

Kipfern is used as monotherapy, or, in case of severe dehydration, in conjunction with the administration of an infusion solution. For severe diarrhea, antibiotics are additionally used.

Hepatitis caused by viruses:

• Children under 7 years old are assigned 50 thousand. IU per 1 kg of weight. The entire dose is divided into two doses. The duration of the course is at least 14 days. The first week the drug is injected daily, the next - with a three-day interval. The general course of treatment can be extended to 3-4 weeks for chronic, sluggish hepatitis.

Chlamydia therapy:

• If girls find latent forms of chlamydial vulvovaginitis without inflammatory processes in the reproductive organs, treatment is prescribed for 1 suppository per day. The entire course of treatment can take up to 10 days. In this case, probiotics are additionally prescribed.

Kipferon - candles for children (positive reviews in most cases), which are used from infancy in the treatment of genital herpes. The disease is treated within 10 days, the course is 1 candle per day. In some cases, repeated therapy is possible.

Side effects

Like many other drugs, Kipferon has its drawbacks. These are allergic reactions caused by the active substance, but more often by additional components. They manifest themselves as mild itching, redness, swelling or a rash that appears in the mucous membranes. In this case, you should stop using the drug and consult a doctor.

Overdose

No cases of excess doses of the drug have been identified.

special instructions

Kipferon - candles for children, reviews of which should be studied before starting their use. The drug belongs to the class of immunomodulatory drugs. For this reason, it should not be used more than once every six months.

The body must learn to independently reflect the "attacks" of bacteria and microorganisms, regulate the immune system. Frequent use of the drug leads to a violation of protective functions, weak resistance of the body, which contributes to the frequent relapse of diseases.

Drug interactions

According to the results of clinical studies, Kipferon can be used in combination with antibiotics, probiotics, but only under the strict prescription of a doctor.

Doctors do not allow some groups of drugs to be used together:

• Amphotericin B. Combination with this antibiotic contributes to the risk of kidney damage.
• Dicarbazine. An immunosuppressive drug and Kipferon taken together increase the risk of liver damage.
• Doxorubicin, Pegaspargase. The combination of interferon and antineoplastic agents enhances the toxic effects of drugs.

Analogs

Drugs similar to Kipferon in action, but differing in active and additional substances:

Name	Compound	Action	From what age
Genferon	Recombinant interferon, taurine, benzocaine	Systemic and local immunomodulatory drug, antioxidant, antiviral action.	From 7 years old
Genferon Light	The main substance: interferon alpha; auxiliary: taurine, macrogol, polysorbate.	Combined agent with antiviral, antioxidant effect.	Children under 7 years old are prescribed 125 thousand. IU
Viferon	In addition to interferon, the drug contains ascorbic acid, alpha-tocopherol, sodium ascorbate, cocoa butter and confectionery fat. The antiviral activity of interferon increases when combined with alpha-tocopherol acetate and ascorbic acid.	Suppositories are effective in combating colds, their complications: ARI; flu; pneumonia.	In the complex therapy of ARVI, children under 7 years of age, including newborns, are prescribed 1 suppository per day, an interval of 12 hours, a course of 5 days, with complex therapy of infectious inflammatory diseases is prescribed for children under 7 years old, including newborns, 1 dose 2 times a day, with a 12-hour interval.
Laferobion	Immunomodulatory drug	Acts as an antiviral agent	Children are prescribed as part of the complex therapy of acute respiratory viral infections, pneumonia, 1 suppository every 12 hours, the course of treatment is 5 days.

It is undesirable to start using Kipferon, as well as its analogs, without the consent of the attending physician. The drugs belong to the group of additional agents, they are not able to replace antibiotics, antiviral drugs.

Terms, conditions of sale and storage

Rectal suppositories are best kept in a cool place, protected from light and moisture. Available without a prescription, stored for no more than 1 year.

Price in pharmacies in Moscow, St. Petersburg, regions

Suppositories can be purchased at many regional pharmacy stores or ordered from an online pharmacy.

Region	Pharmacy	Price	Qty.
Moscow	Doctor Stoletov	190-418 rubles.	5 pieces.
Mosapteka	389-418 rubles.	5 pieces.
Zdravcity	RUB 629	10 pieces.
Samson Pharma	389-430 rubles.	5 pieces.
St. Petersburg	Planet Health	346 r	5 pieces.
Pharmadom	464 r	5 pieces.
Ozerki	RUB 371-392	5 pieces.
Doctor Stoletov	397-405 rubles. RUB 605–679	5 pieces. 10 pieces.
Planet Health	475-530 rubles.	10 pieces.
Permian	Permpharmacy	RUB 549-699	5 pieces.
Permpharmacy	RUB 859-939	10 pieces.
Khabarovsk	DFC	448-800 rubles.	5 pieces.
Yaroslavl	Leader-Farm	349–659 rubles.	5 pieces.
Planet Health	RUB 530	5 pieces.
Grozny	Hamal-Trading	422 r	5 pieces.
Grozfarm	659 r	5 pieces.
Ulyanovsk	Aliya	RUB 557-569	10 pieces.
Aliya	350-370 rubles.	5 pieces.
Tomsk	Pharmacy from warehouse	310 RUB	5 pieces.
KSP Mokrushina	RUB 419	5 pieces.
KSP Mokrushina	RUB 627	10 pieces.
Smolensk	Nadezhda Pharm	RUB 338–433	5 pieces.
Medea Farm	707-736 rubles.	10 pieces.
Zdravcity	RUB 631	10 pieces.
Saratov	Pharmacy number 1	494 r	5 pieces.
Ozerki	RUB 499-589	5 pieces.
Doctor Stoletov	RUB 542-579	5 pieces.
Nadezhda Pharm	RUB 611	10 pieces.
Zdravcity	RUB 631	10 pieces.
Ozerki	RUB 663–781	10 pieces.
Pharmacy number 1	RUB 741-912	10 pieces.
Doctor Stoletov	RUB 912	10 pieces.

The remoteness of the region from the center affects the cost of the drug. Often the price depends on the transport logistics.

The infant's body is weak and unable to resist disease. Kipferon for children is designed to help independently cope with viral infections, to prevent the risk of complications. The form of the drug in the form of suppositories, according to the parents, is convenient and effective.

Video about Kipferon candles

Review of the doctor about the drug Kipferon: