Singulair for children. Reviews, instructions for use, analogues, price

Singular is a drug that is used to treat children and adults with various pathologies with sides of the respiratory system. It has pronounced therapeutic properties, it helps to cope even with advanced diseases. Parents' feedback on the action of the drug is predominantly positive, which proves its safety and effectiveness.

Forms of release and composition of the drug

A pharmacological agent can be found on the shelves of almost every pharmacy. It is produced by many pharmaceutical companies in the form of chewable tablets. The tablets themselves are packaged in blisters of 8 pieces. An individual cardboard box can contain 2 such plates, as well as detailed instructions explaining the rules for using the medication.

Montelukast is present as the main active ingredient in the preparation.

There are also auxiliary ingredients in the composition:

• Microcrystalline cellulose.
• Aspartame.
• Beckons.
• Iron oxide.
• Titanium dioxide.
• Magnesium stearate.
• Dye.
• Flavoring agent.

The amount of the main substance in the tablets may differ. The most popular are tablets with a dosage of 4 and 5 mg, but a drug with a dose of 10 mg is available, which in most cases is used for therapy in adults.

Pharmacological properties

Singular for children (reviews of the remedy are mostly positive) can be used in the treatment of pathologies of the respiratory tract due to the content of montelukast. The substance has several pharmacological properties.

The most important is the ability to block the production and activity of leukotriene receptors in bronchial epithelial tissue. Additionally, the medication is able to relieve bronchospam and prevent its re-development. At the same time, the condition of the patients improves significantly, even if they suffer from any chronic pathologies of the respiratory system.

In addition, the remedy is fast-acting, since a therapeutic effect is noted within 2 hours. Additionally, the drug somewhat reduces the viscosity of mucus produced by the bronchi, and also stimulates its formation, which allows with greater efficiency to evacuate pathogenic microorganisms that worsen the condition of the inner walls bronchi.

Thanks to the complex action, the patient's condition improves and the progression of the pathology slows down, followed by the acceleration of tissue regeneration. When used correctly, the effect is observed within a few days.

Pharmacodynamics and pharmacokinetics

After ingestion, the drug is actively absorbed and begins to act, concentrating in the tissues of the bronchi. Montelukast acts on the interleukin receptors of the epithelial tissue of the bronchi, which leads to the elimination of organ spasm and respiratory failure.

Thanks to this, the patient's condition improves not only in acute inflammatory pathologies, but also in the advanced course of bronchial asthma. When a large amount of mucus is produced, pathogens are quickly removed from the bronchi and the process of restoring the affected areas is started.

Additionally, mucus envelops the walls of the organ, which reduces the negative effects of bacteria on them, as well as negative environmental factors. If a patient has a viscous secretion in the bronchi, recovery slows down, since there is a difficulty in removing it. However, montelukast leads to a significant dilution of the secretion, so the process is accelerated.

When the tablet is chewed, the active components after a while enter the systemic circulation and bind to blood proteins. The maximum plasma concentration is observed 2 hours after consumption. At the same time, the most pronounced therapeutic effect can be noted, which lasts for 12-18 hours, depending on the characteristics of the patient's body.

The bioavailability of the active substance of the composition is close to 75%. It should be noted that taking with food reduces the bioavailability index by about 10%, but does not weaken the effectiveness of the drug. Metabolism of montelukast occurs in the liver, where the component is broken down into several substances.

It should be noted that in patients with liver pathologies, there is a slowdown in the processing of the ingredient, as well as a slight weakening of the therapeutic effect. The period of evacuation of metabolites from the body is approximately 2 days. In patients with diseases of the gallbladder and duct, this time is extended by several hours.

The main amount of the decay products of the active component is excreted in the bile, a small part in the urine.

Indications for use

Singular is used not only for the treatment of children. Patient reviews confirm the effectiveness of the drug in adult therapy.

The main indications for the appointment:

• Treatment of bronchial asthma in patients suffering from hypersensitivity to medicines based on acetylsalicylic acid.
• The need for long-term therapy of bronchial asthma in its severe course. In this case, not all medications are allowed to be used, but Singular can alleviate the patient's condition.
• Obstructive forms of bronchitis of varying severity.
• Lack of a sufficient amount of bronchial secretions, which makes it difficult for the excretion of microbes.
• Severe allergic rhinitis, which manifests itself not only in the form of seasonal exacerbation, but also in various disorders of unspecified origin.
• Prevention of bronchospasm in children and adults with regular and heavy physical exertion.

In addition, the medication is often prescribed to prevent the development of bronchial asthma in patients preschool age as a result of serious physical exertion, for example, during professional activities sports.

Contraindications

The drug is not used in case of intolerance to its components, as it can cause serious complications. With caution, the remedy is prescribed to elderly patients suffering from heart failure, coronary heart disease, and also having a tendency to thrombosis.

During the recovery period after myocardial infarction. Ischemic stroke and severe injuries of the extremities, spine, the medication is also not used. It is contraindicated during pregnancy and breastfeeding, since the effect on the fetus and the mother's body is not fully understood.

With extreme caution, a medication is prescribed to patients who regularly undergo a course of therapy with glucocorticosteroids, as well as drugs that affect the narrowing and expansion of the bronchi.

At what age can the drug be used

Singular for children (it is better to study reviews of the drug before using it) is used from 2 years old. A child under 2 years of age is almost never prescribed a remedy.

Despite this, the pediatrician makes a decision on an individual case-by-case basis. The tablets have a pleasant taste and aroma, so children do not have problems with chewing.

Instructions for use, dosage

The tablets are intended to be chewed. The dosage in each case is selected individually. A child from 2 to 6 years old is prescribed a 4 mg tablet in the evening.

In this case, the use should be carried out under the supervision of adults. The duration of treatment is approximately 2-4 weeks, depending on the severity of the symptoms. Longer use is possible if symptoms persist.

Children from 6 to 14 years old are prescribed 5 mg of the drug in the evening for 3-6 weeks. With a mild course of asthma, when attacks are rare, it is possible to stop using the medication. If the patient had attacks of bronchial asthma a few days before the start of treatment with Singular, he took corticosteroids, the appointment of the drug is postponed for 5-7 days.

Adults and patients over 15 years of age are prescribed a single dose of a 10 mg tablet. Be sure to take the reception in the evening or before bedtime. The healing effect lasts throughout the night and almost all day.

Even with the onset of severe remission, it is recommended to use the medication for a week in order to prevent complications. The duration of the course of treatment for adults is determined individually, taking into account the condition and the presence of complications.

It is recommended to use the product separately from food, which will increase the rate of absorption of the components, as well as maintain the normal level of bioavailability of the active substance.

Side effects

Adverse reactions when using the drug do not occur so often, but affect all organs and systems. However, they can appear in case of compliance with the instructions or its violation.

Organs and systems	Most common reactions
Nervous system	Headache and drowsiness when taking the medication is quite common. In addition, in adult patients, the development of a depressive state, impaired coordination of movements, and dizziness are possible. Sometimes in patients there is not drowsiness, but insomnia, memory impairment, the inability to concentrate on ordinary household manipulations.
Digestive organs	When taking the drug, most often patients are worried about nausea. However, complications from the liver may develop in the form of hepatitis, organ enlargement, yellowing of the skin and pain in the area of ​​the liver projection. In addition, a stool disorder is possible, which manifests itself in patients in the form of constipation or frequent loose stools, depending on the characteristics of the body. In some cases, abdominal pain appears, flatulence is noted.
Musculoskeletal system	Pain in the joints and muscles is observed most often in adult patients. Sometimes adolescents have similar disorders.
Hematopoietic system	Violation of the integrity of blood vessels and a decrease in the number of platelets in the blood lead to a deterioration in clotting. In this case, any minor injury provokes the appearance of hemorrhage under the skin. It should be noted that many patients develop bruising even in the absence of bruises or other injuries.
Skin	An allergic reaction to the drug manifests itself in the form of a skin rash and itching, as well as hives. Symptoms in each case are manifested in different ways, but significantly worsens the patient's condition.

In addition, there may be an increase in heart rate, as well as the appearance of edema of the extremities. In some patients, the body temperature rises, in children, a febrile state may develop.

In the event of negative reactions from the internal organs, it is worth stopping the medication and visiting a doctor.

Overdose

Singular for children (patient reviews may be negative due to intolerance to the components of the composition) rarely leads to an overdose, provided it is used correctly. However, prolonged use of an increased dose of the medication will certainly lead to the development of severe symptoms.

At the initial stage, all adverse reactions are aggravated. Nausea provokes vomiting, headache worsens, and discomfort in muscles and joints leads to limited mobility. In addition, in adults with an overdose, hallucinations may appear, there is a clouding of consciousness and an inability to navigate in space.

The allergic reaction is also exacerbated. Children may develop acute urticaria or Quincke's edema. In the first case, large red spots appear on the skin, they provoke severe itching, forcing the child to scratch the affected area. These scratching worsen the condition of the skin, disrupt the surface layer and can lead to tissue infection.

Urticaria is often accompanied by lacrimation and sourness of the eyes, which occurs with the development of an allergic form of conjunctivitis. Allergic rhinitis is possible, in which a large amount of clear liquid mucus is secreted from the nose.

With Quincke's edema, edema of the mucous membranes of the upper palate and pharynx is usually observed, which leads to respiratory failure and, in the absence of therapy, can provoke death.

The appearance of signs of an overdose is considered a reason for refusing to use the drug and contacting a doctor in order to obtain symptomatic treatment.

special instructions

If the drug is used to treat chronic obstructive bronchitis, it is worth increasing the amount of fluid consumed per day. Better to give preference to warm tea, fruit drink or herbal infusions. This will increase the amount of phlegm and make it less viscous in order to facilitate excretion.

When treating children from 2 to 5 years old, a thorough examination is carried out, which makes it possible to exclude the presence of contraindications for use.

In addition, with a long course, it is recommended to regularly visit a pediatrician in order to monitor the effectiveness of therapy, as well as add any additional medications. If the patient suffers from chronic liver pathologies, the doctor recommends regularly donating blood for biochemical research in the laboratory.

As a rule, in case of any negative changes, another remedy with similar therapeutic properties is selected. When combining the drug with other medicines, the doctor takes into account the body's reaction to the combination, as well as the peculiarities of the course of the disease.

Drug interactions

Singular for children (reviews of the tool help to assess its effectiveness before using it) and adults are quite often used in combination with other medicines aimed at eliminating symptoms of bronchial asthma.

The drug is often prescribed in combination with corticosteroids in the form of tablets or solution for inhalation. In this case, the dose of corticosteroids can be reduced when improvement occurs. In addition, the medication can be used simultaneously with drugs aimed at expanding the bronchi. They enhance its effectiveness.

Quite often, the patient is first prescribed bronchodilators, after which Singular is added to the therapy in order to increase the therapeutic effect and shorten the treatment period. Usually, chewable tablets are not prescribed concurrently with immunostimulants, hepatoprotectors, and antacid medications.

Analogs

In some cases, the use of Singular is not possible. Its high cost is not suitable for many, so they try to find a substitute with similar properties.

The most popular analogues:

• Singlon - a product based on montelukast, produced in the form of tablets for oral administration and chewable tablets. Possesses pronounced anti-inflammatory, bronchodilatory properties. It is prescribed for the treatment and prevention of various forms of asthma in adults and children.
• Montelukast - a tablet medication based on the active ingredient of the same name. Tablets are intended for oral administration and for chewing, available in different dosages. The drug is aimed at treating and preventing pathologies of the respiratory system, has pronounced properties and rarely provokes complications.

There are other analogues of the drug, but these drugs have a low cost and have the same effect, therefore they are used most often.

Terms, conditions of sale and storage

You can buy the medication with a doctor's prescription. It is allowed to store it for 2 years, it is forbidden to use it after the expiration date.

The drug is best kept out of the reach of children in a dark place, protected from moisture.

Price in pharmacies in Moscow, St. Petersburg, regions

In pharmacies in St. Petersburg and Moscow, the product can be purchased for 900-1100 rubles. In the regions, the price is slightly lower and is about 800 rubles.

Singular is a popular medicine that is often used for children and adults in order to eliminate the symptoms of pathologies of the respiratory system. Reviews of the drug are mostly positive, which proves its high quality and effectiveness.

Video about the drug Singulair

Doctor's review of Singulair: