Depressive disorders of the psyche, stress and nervous tension are registered in modern society more often. To help solve the problems associated with psychomotor disorders and depressions in different degrees of manifestation called Fluvoxamine.
The drug belongs to the group of modern antidepressants of selective inhibitors of serotonin reuptake in the brain.
The preparation Fluvoxamine is available in the form of tablets, each of which has a special coating - a film membrane. The main active substance is fluvoxamine maleate. In pharmacies, you can buy packs of tablets that contain 50 or 100 mg of active ingredient.
The active ingredient is a white powder, odorless. It dissolves in alcohol( ethyl) and chloroform, in water the processes are worse. In diethyl ether, the substance does not dissolve at all.
Contents
- Pharmacological profile
- Mechanism of action
- Indications and contraindications for use
- Instruction for use
- Overdose and adverse reactions
- Unconcerned opinion
- Purchase of medication and its analogues
Pharmacological profile
Fluvoxamine is a drug with mild effects on psychomotor activity. The substance selectively inhibits serotonin reuptake, partially inhibiting the re-uptake of substances such as dopamine and norepinephrine.
Formula fluvoxamine maleate
There is medical information about the successful use of the drug for the treatment of children and adolescents aged 8 to 17 years.
The drug should be taken orally. It is well and quickly absorbed, hitting the digestive tract. The medicine can be used, both before meals and after - the effectiveness of the absorption process does not change from this.
Bioavailability, according to studies, is more than 50%.The connection with proteins contained in the blood( albumin) is 80%.
Substances that make up the drug easily penetrate into breast milk, so the drug is prohibited for pregnant and lactating.
Relief is noted after 3-8 hours( depending on the severity of the disease).The positive effect of taking the drug is observed for an average of 14 hours, with a long( multiple) admission - up to 22 hours.
Metabolic processes are performed in the liver. They involve a special isoenzyme, and the result of the processes is the formation of active and inactive metabolites. They are excreted in the urine after 71 hours. Up to 3% of the substance remains unchanged.
Mechanism of action
The drug begins to work immediately, only getting into the body. The main amount of active substance is absorbed through the mucosa in the digestive tract. The load on the kidneys and liver is negligible, so the drug is permitted, but under strict doctor's supervision. If there are liver disorders, tests must be submitted. In case of renal insufficiency, the taking of the remedy is prohibited.
Taking the drug helps to increase the transmission of serotonin and simultaneously reduce its turnover. Also, the active substance blocks the inverse capture of it, occurring in platelets. It does not affect the receptors.
Indications and contraindications for use
The main indications for the use of the drug Fluvoxamine:
- of depression of varying severity;
- anxiety, panic attacks;
- obsessive-compulsive disorder.
The doctor may also recommend the use of medication in the therapy of other mental disorders.
Because of its specificity, the drug has a number of contraindications to use. The main ones are:
- kidney failure;
- liver disease( including cirrhosis);
- pregnancy;
- lactation period;
- diabetes;
- allergic reactions and intolerance of substances that make up the composition;
- age( to 8 years and after 60).
Also use with caution if the patient has the following health problems:
- epilepsy;
- drug dependence;
- mania, hypomania;
- convulsive conditions;
- myocardial infarction.
In order to exclude all possible complications, it is recommended that a specialist be examined so that he can make a program of treatment. Including, the doctor will determine the necessary dosage, taking into account the disease( basic), age, state of health.
Instruction for use
The dosage and application regimen during the main treatment or prevention of relapses is calculated exclusively by a specialist. The main diagnosis, the severity of the disease and the general health of the patient are taken into account. For this, a survey is conducted-tests and computer studies are submitted.
If there are no specific instructions, then at the first stages of treatment, no more than 100 mg of funds per day are prescribed. After, according to the results of primary therapy, it can be increased to 150-200 mg( daily dose).Tablets are taken orally whole. It should be washed down with a lot of still water. Doses for children can be reduced.
The maximum daily dosage should not be more than 300 mg. Large doses should be taken fractionally - for 2-3 hours during the day.
The course of treatment lasts a different amount of time - it depends on the severity of the disease at the beginning of therapy, the rate of response of the body to the drug. If there is an improvement, the dosage may be reduced.
Prophylaxis with the use of the drug continues for the next six months after recovery. Dosage in this case is also chosen by the doctor, based on the results of therapy.
Overdose and Adverse Reactions
In case of exceeding the dose indicated by the doctor or when taking more than 300 mg of medication a day, an overdose occurs, which is expressed by:
- by dizziness;
- with nausea;
- drowsiness;
- disorder in the gastrointestinal tract;
- pain.
Side effects of the drug are expressed: 
- from the nervous system - headache( sometimes migraine), dizziness, asthenia, insomnia, or drowsiness, anxiety;
- from the digestive tract - nausea, anorexia, dry mouth( strongest most often), dyspepsia, vomiting, diarrhea, abdominal pain;
- cardiovascular system and blood react so - palpitation, arterial hypertension;
- respiratory system responds to the medication in a number of cases by the occurrence of upper respiratory tract infections, yawning;
- also side effects can arise from of the genitourinary system , they are expressed in violation of ejaculation, a decrease in libido and impotence.
- Delayed urination, chills, and sweating - Other side effects of .
It is not recommended to use the drug in combination with alcoholic beverages. If a person takes other medications in parallel( not necessarily related to the treatment of the nervous system or depression), consultation with the doctor is required, since side reactions may occur due to the incompatibility of the drug components.
Admission by children is possible, it is recommended to start using when the child is 8 years old. In most cases, a person can drive a vehicle, but experience drowsiness at the same time.
Unconcerned opinion of
Reviews of people who drank Fluvoxamine are mixed.
The drug was administered for 14 days, but after the first 4 days I began to notice specific problems associated with the genitourinary system. It was necessary to refuse further treatment, despite the good results for the underlying disease.
Michael
The action is positive, the joy and desire to do something appeared, but I really wanted to sleep.
Anastasia
The drug shows itself well, just started taking, literally 2 days have passed. Anxiety disappeared, gloomy thoughts became not so intrusive. While satisfied.
Peter
As a doctor I want to warn that the drug can not be used for self-treatment. The attending physician prescribes an accurate dosage that is compatible with the existing disease.
Stepan
Purchase of medicine and its analogs
The drug is available in tablets of 50 and 100 mg. The price of Fluvoxamine averages from 930 rubles, and its analogs are also available for purchase: Fevarin, Deprivoks.
The package should be stored in a dry place and protected from children's access. Temperature indicators - not above 25 degrees.
From pharmacies is released only on presentation of a prescription.
