Chondroguard refers to preparations of a group of chondroprotectors that have a retarding effect on degeneration processes localized in the joint tissue and protect the cartilage from destruction.
Due to the presence of the active substance( chondroitin sodium sulfate), which is part of the drug, the agent stimulates the processes of restoring the tissues of the joint apparatus and performs a function of a kind of lubrication between the joint surfaces.
Contents of the article
- Pharmacological action
- Pharmacokinetics of the preparation
- Drug components
- Mechanism of action of the preparation
- Indications for use
- When is the use of the drug unsafe?
- Usage and Dosage Rules
- Cases of overdose
- Special instructions
- Interaction with alcohol
- What doctors think about medicine
- Direct speech of doctor
- Patients share their impressions
- Purchase and storage of medication
- Worthy replacement is
Pharmacological action
Chondroguard influences the exchange processesin the hyaline cartilage and at the same time reducing the degenerative changes in articular cartilaginous tissue, contributes to the process of its recovery through stimulisynthesis of proteoglycans.
As a result of the use of the drug, soreness decreases and the mobility of the damaged joint increases.
In the treatment of degenerative changes in the joint tissue, noticeable improvements can be diagnosed after 2 weeks after taking the drug: the mobility of the affected joint is markedly increased, with the pain significantly reduced, the clinical signs of the impairment are smoothed or almost completely disappear.
At the end of the course of treatment, the therapeutic effect of the use of the remedy remains for a long time.
Pharmacokinetics of the preparation
With intramuscular injection of the drug, half an hour after injection, chondroitin sulfate of sodium is rapidly penetrated into the blood, the maximum concentration of which is reached after an hour.
For 2 days the concentration of the drug in the blood decreases.
The accumulation of chondroitin sodium sulfate occurs mainly in the cartilage of the articular apparatus and the synovial membrane does not prevent the penetration of the drug into the joint.
Drug Components
The drug is presented in the form of ampoules with a clear or yellowish tint content, when opened, the liquid has a distinct smell of benzyl alcohol.
One ampoule of the drug, in a volume of 1 ml or 2 ml, includes:
- chondroitin sodium sulfate( ratio: in 1 ml / 100 mg, in 2 ml / 200 mg), which is the active substance of the drug;
- excipients: water for injection, sodium disulphite, benzyl alcohol, sodium hydroxide.
Mechanism of action of the drug
The effectiveness of the drug is due to the action of the active substance( chondroitin sodium sulfate) on the articular and cartilaginous tissue.
As a result of the use of the drug, processes of degeneration and dystrophic changes in the cartilaginous tissues are suspended, and the motor activity of the joint is preserved.
Excipients included in the preparation have an analgesic and anti-inflammatory effect of the synovium, contribute to reducing edema of the inflamed joint.
Reception Chondroguard provides a normalization of the process of calcium-phosphorus metabolism, which contributes to the strengthening of bone and cartilaginous tissue of the body.
Indications for use
Indications for the use of Hondroguard are diseases of the spine and joints associated with degenerative-dystrophic changes:
- spondylarthrosis;
- osteochondrosis;
- deforming arthrosis of small and large joints;
- osteoporosis;
- osteoarthrosis of peripheral joints and spine;
- is a rehabilitation period associated with the provision of therapeutic treatment for the rapid healing of bone tissue as a result of cracks, bruises and fractures of bones.
When is the application of the tool unsafe?
Contraindications for chondroguard injection:
- thrombophlebitis;
- susceptibility to thrombosis;
- open bleeding, low blood coagulation index;
- pregnancy and lactation period( the safety of the drug for intrauterine fetal development and breast milk is not currently proven);
- child's age;
- hypersensitivity to individual components of the drug.
Usage and Dosage Rules
Chondroguard is a medicinal preparation in the form of a solution for intramuscular injection. Presented in the form of sealed ampoules, each volume of 1 ml or 2 ml.
According to the instructions for use, begin taking Chondroguard with a starting dose of 100 mg, which is administered once every two days.
After 4-5 injections, an assessment should be made of the tolerability of the drug and the availability of therapeutic effects on the patient.
The full course of treatment consists of 25 to 30 intramuscular injections.
If necessary or for medical reasons, treatment can be resumed after 6 months.
Cases of overdose
Until now, medicine has not known cases of drug overdose.
At the time of taking the medication, there may be side effects expressed by allergic reactions( dermatitis, itching, urticaria, burning) and hemorrhages localized at the injection site.
Special instructions
If you experience any of the signs of an allergic reaction, you should cancel the drug.
It is prohibited to administer the drug near an open wound, since the action of chondroitin sodium sulfate may provoke increased bleeding.
The use of the drug does not adversely affect the ability to drive a vehicle, it is not a contraindication to work with the use of potentially hazardous production mechanisms.
With the simultaneous use of drugs and antiaggregants, anticoagulants, fibriolitics, the effect of the latter can be intensified. As a result of this, requires constant monitoring of blood coagulation indicators and.
Due to the lack of data on the safety of the use and the effect of the drug on the fetal development of the fetus and breast milk, the use of chondrohard during pregnancy and during breastfeeding is prohibited.
Interactions with alcohol
When combined with alcohol and alcohol, dizziness may occur. The level of risk of allergic reactions increases.
Drinking alcohol and medication at one and the same time can adversely affect the health status in general.
In addition, alcoholic beverages contribute to rapid removal of the drug from the body, thereby weakening the therapeutic effect.
What Do Medics Think About Doctors and Patients
Chondroguard is a popular means for the treatment of joint diseases, doctors of Russian clinics rather actively assign it to their patients.
Based on the opinions of doctors, it can be concluded that the effectiveness of Chondroguard depends on the individual characteristics of the patient's body and the severity of the disease.
The number of patients who, after the use of the drug, there has been a significant improvement in the condition, is much more than those that the medication did not help.
According to most experts, this drug does not cure the disease, but it can have a persistent therapeutic effect.
Direct speech of the doctor
Very often in diseases of the musculoskeletal system, patients are assigned chondroprotectors, these drugs have the same effect on the diseased joint, but significantly differ in cost.
I advise my patients to take Chondroguard, which is an effective medicine and is affordable.
In the second week of taking the drug, patients notice significant improvement, the pain subsides, inflammation and edema decreases.
In my practice, there was not a single case of allergic reaction as a result of taking the medicine. Another undeniable plus of the drug is the way of administration into the body through intramuscular injections, which accordingly does not have a negative impact on the patient's gastrointestinal tract.
Margarita Anatolyevna, specialist of the highest category
Patients share their impressions
I have suffered pain in the knee joint for several years already. During this time, I went around a lot of doctors and clinics, where I was prescribed various drugs: pills, ointments, injections, but there was no positive effect - the pain continued and it seemed that it was getting worse.
I accidentally learned about Hondroguard and decided to try, there was still nothing to lose. And after 10 procedures, he noticed that the pain became much less. By the end of the course of treatment, I understood the meaning of the phrase "joy of movement", now I can live without painful sensations when walking. I will definitely repeat the course of admission in another six months.
Andrey Romanov
I read about the preparation on the Internet, the reviews are just wonderful, people are happy and practically get up on their feet after the course of treatment. When Hondrogaard tried it herself, she realized that these producers praise their drug right and left. He did not help me at all.
Completed the full course of treatment - 30 injections, the result was zero. The pain remained and, in parallel, I had to take painkillers, because sometimes I could not even stand up.
Olga Vasilevna
With strong knee pains, especially at night, on the recommendation of the doctor, she pierced 10 injections of 1 ml of Hondroguard and 10 more injections of 2 ml each. Thanks God the pain let go.
Now I will definitely undergo such a course of treatment 3 times a year. Before that I pierced 10 injections of Aflutop - absolutely no result.
The effect of treatment will be better if at least 10 physiotherapy procedures are added to Hondroguard. I wish everyone good health and life without pain!
Olga Pakhomenko
Purchase and storage of medicament
The drug Chondrogard is available as a solution for injection. Ampoule volume can be 1 ml or 2 ml.
The agent is placed into 5 ampoules per contour cell package. Along with the instruction for use, one or two contoured cells with ampoules of 1 ml or 2 ml are placed in a pack of cardboard, it is possible to put 5 contour packs with ampoules of 2 ml into a pack of cardboard.
Depending on the manufacturer and place of sale, the price of Hondroguard can differ and is on average:
- 10 ampoules of the preparation in the volume of 1 ml can be bought for 650 r;
- for 10 ampoules with a volume of 2 ml, it is necessary to pay about 1,230 rubles.
Store the drug in a dark place protected from direct sunlight, at a temperature not exceeding 25 ° C.
A prerequisite for storage is the restriction of children's access to medicines.
Shelf life - 24 months.
Do not use after 2 years from the date of manufacture.
The drug is dispensed from a pharmacy by prescription.
Decent replacement is
Chondroguard analogues are divided into two groups, differing in the composition of the components.
The first group - chondroprotectors, have in their composition the same active substance, they include the following drugs:
- Mukosat;
- Artradol;
- Structum;
- Chondroxide;
- Chondrolon.
The therapeutic effect of chondroprotectors is the same, but their cost is an order of magnitude higher than that of Hondroguard.
The second group is a medicinal product consisting of natural( natural) components consisting of marine fish cartilage or young calves.
These include: a drug in the form of tablets Rumalon, solution for injections Aflutop. The cost of natural drugs is much higher, and the impact is controversial, depending on the individual characteristics of the organism and the severity of the disease.