Pros and cons of carbamazepine can be learned by studying the instructions for use, reviews of doctors and the advantages of analogues

Carbamazepine is a drug against epilepsy.

Used for severe convulsive seizures, as an anticonvulsant drug.

This product has a positive effect on the organism:

• anticonvulsant action;
• has antidepressant properties;
• has a positive effect on patients with personality disorder;
• improves their mental state and promotes prompt rehabilitation and adaptation in society;
• prevents the onset of epileptic seizures and reduces the incidence of their occurrence;
• is very effective in the application for adolescents, helps to remove the symptoms of anxiety, depressiveness, suppresses aggression;
• is fully digested, although it takes a lot of time for this. Food does not affect the process of "absorption" of the drug.

Pharmacokinetics

What happens afteringestion of the drug in the organism:

1. As mentioned earlier, the drug needs some time to assimilate. The key chemical substance of the drug reaches its highest concentration in the blood plasma 4-24 hours after ingestion.
2. The substance is released within the next several days.
3. The drug should be used especially gently in pregnancy and lactation, as it has the ability to penetrate into breast milk.
4. It is also necessary to take the drug under supervision for children and the elderly.
5. Especially neatly it should be used with other anticonvulsants.

Indications for use

Instructions for use on the drug Carbamazepine indicates that a good reason for prescribing the drug can serve:

• epilepsy;
• is an abstinence syndrome;
• defeat of the trigeminal and glossopharyngeal nerves;
• prophylaxis for bipolar affective disorder.

Usage of preparation:

1. For adults, the pill is taken on the floor( inside) 2-3 r. / Day. Step by step increasing the dose to 4-6 r / day.
2. For children it is recommended to take a medicine of 20 mg per kilogram per body weight per day. Very effective in the application for adolescents, helps to remove the symptoms of anxiety, depression, suppresses aggression.

The use of carbamazepine allows the use of other antiepileptic drugs in parallel with the use of this product .

The transition to the use of carbamazepine should not be a surprise to the body, that is, it must be gradual.

It is worth to reduce the dose of another drug.

As with the beginning of use, cessation should be done slowly, gradually.

Contraindications

The drug is not recommended for use with:

• the presence of hypersensitivity to individual constituents of the drug;
• varieties of heart block, in which partial or complete termination of the impulse from the atria to the ventricles;
• for serious violations of kidney and liver, with prostatitis, etc.

Use of the drug for violations of kidney and liver

For violations of kidney and liver, the drug should be used with caution and periodically examined by a doctor.

Mechanism of action

Instructions for use, which complete tablets Carbamazepine indicates that the mechanism of action of the product has not been thoroughly studied. Carbamazepine promotes to stabilize the work of overexcited nerve fibers , prevents the appearance of repeated neuronal discharges.

The main task of the key chemical Carbamazepine - finlepsin, is to eliminate the possible reappearance of sodium-dependent potentials with the help of sodium channels.

Instructions for Use

We will study in more detail the instructions for use with carbamazepine.

How to use

It should be remembered that

1. is for adults .Orally, regardless of the time of ingestion. It is recommended to drink plenty of water, the frequency of reception: 2-3 times a day. During the course, the frequency of use increases. If your work involves concentration of attention, try to take the drug immediately before lunch break, so that the peak of the action is due to non-working time. The second method is recommended before bedtime. Combines with other antiepileptic drugs.
2. People of mature and advanced age should start taking the drug with smaller doses. This is explained by the sedative effect of the drug. It is also recommended to take the drug under the supervision of a doctor.
3. For children. According to doctors, it is not advisable to use infants, as in the case of older people, treatment starts with small doses of the drug. Dosage depends on the age and body weight of the patient. Recommended use after school day in school, becausein some cases, the drug may have a retarding effect and weakness.

Forms of release

The product is available in tablets of 10 pcs.in the outline cell pack.

500, 600, 1000 or 1200 pieces.in a can of polymer packed in a cardboard box.

Dosage Medications

For epilepsy:

1. Children under five years of age are recommended to take a medication of 20 mg per kilogram per body weight per day, increasing the dose by 20-50 mg daily.
2. For children from the age of five, the recommended dose is 100 mg / day, followed by a rise of 100 mg / week. Dose / day.is divided into several receptions.
3. Drug consumption( inside) for adults is to take a pill at the floor of 2-3 r. / Day. Step by step increasing the dose to 4-6 r / day.
4. For patients in old age, the initial dose is 100 mg 2 times / day.

With , the nervous system due to diabetes mellitus - 0.2 g 2-3 times / day

With , the trigeminal nerve lesion is 150-400 mg, followed by an increase of 200 mg every day until pain ceases completely( usually up to 800mg), then the dose is again reduced to a min dose, with the effect remaining.

Non-diabetes - 0.2 g 2-3 times a day.

And bystientnyj an alcoholic syndrome - 0,2 g 3 times a day.

Overdose and special instructions

Symptoms that occur after using too large a dose of drug:

• dizziness;
• drowsiness;
• urinary retention;
• inability to navigate in space.

Treatment for overdose: rinse the stomach and conduct a course of symptomatic treatment.

Additional instructions

In case of malfunctioning of the kidneys and liver, the drug should be used with caution and periodically examined by a doctor.

The course of treatment with carbamazepine should be started with minimal doses, gradually increasing the dose until the required therapeutic dosage level is achieved.

Side effects of

Among the main:

• dizziness;
• hallucinations;
• depressiveness;
• aggression;
• rash;
• malaise;
• abnormal involuntary movements;
• nausea, vomiting;
• headache, etc.

Special instructions

Before you start using the drug, the patient needs to take blood tests, urines, determine the level of iron. Analyzes require weekly monitoring in the first month of use, and then monthly.

Drug and alcohol

The indications for use indicate that the drug can be used in the treatment of alcohol withdrawal syndrome.

You might think that alcohol can be consumed in treatment, because the use of the medicine can "annul" the effect of alcohol. But, the use of alcohol is contraindicated during the treatment period.

Combination with other

medications Application in parallel with other medications:

1. The drug promotes the metabolism of cyclosporine and warfarin, resulting in a reduction in the duration of these drugs.
2. Danazol and verapamil inhibit the absorption of the drug, resulting in side effects of carbamazepine.
3. Cisplatin and doxorubicin reduce the time required to assimilate carbamazepine and reduce its plasma performance.
4. In some patients diltiazem worsens the absorption of carbamazepine, which leads to an increase in its concentration in the blood plasma.

In pregnancy and lactation

The use of the drug during pregnancy can lead to a violation of embryonic development, so the drug should be administered under by a physician.

Side effects of , which can occur in a child during breastfeeding: and a decrease in appetite and extremely rare lethargy.

Admission of children

Children under five years of age are recommended to take a medication of 20 mg per kilogram per body weight per day, increasing the dose by 20-50 mg daily.

For children from age five, the recommended dose is 100 mg / day, followed by a rise of 100 mg / week. Dose / day.is divided into several receptions.

Reviews of Doctors and Patients

Reviews of doctors and patients about the drug Carbamazepine are positive.

Reviews of doctors

Here are some of them:

1. The drug is effective for various types of diseases. It does not cause dependence, and also reduces the incidence of attacks ( Semenchenko SS).
2. I prescribe Carbamazepine to my patients without anxiety for their health. Yes, there are side effects, but in general the drug is effective ( Rovensky MT).

Patient Reviews

Reviews of patients about carbamazepine are not so bright, but also positive:

1. I have been using Carbamazepine for two years under the prescription of a doctor. Now he has completely got rid of seizures, although they used to happen periodically at night ( Constantine) .
2. The level of cholesterol jumped very much during the application. When stopped taking, then from 9.6 fell to 4.4 ( Eugene).
3. I constantly feel malaise and mood swings ( Timothy) .
4. Just started taking until everything is fine. Thank God, the side effects have not yet manifested ( Alexandra ).

Forms and value in rubles

The product is available in tablets of 10 pcs.in the outline cell pack.

500, 600, 1000 or 1200 pieces.in a can of polymer packed in a cardboard box.

On average, the price of carbamazepine lies in the area of ​​ 40-50 rubles.

. Conditions and storage times.

. Store in a place protected from children's access at a temperature not exceeding the room temperature( 250).Shelf life - 3 years.

Leave at pharmacy

In pharmacies Carbamazepine is sold only with a prescription!

Analogs of the drug available in Russia

It should be noted that the analogues of carbamazepine have both pros and cons.

Tegretol

Pros and Cons:

• availability for children;
• the choice of the form of the preparation, in the presence of tablets both for 200 and 400 mg;
• is the highest price compared to other analogues.

Stasepin

Pros and Cons:

• Convenient packaging;
• high price;
• there is no specially designed dosage for children.

Corbalepsin

Pros and Cons:

• Affordable Price;
• availability of a daily form of release;
• no dosage for children.

Mazepin

Pros and Cons:

• Convenient packaging:
• Affordable price;
• bioavailability;
• there is no infant dosage;
• release form is only 200 mg.