Compare Cortexin and its analogues: what is more effective, safer and cheaper?

For the treatment of circulatory disorders in the brain in adults and children from the day of birth, as well as to support the emotional state of pregnant and lactating mothers, a nootropic drug Cortexin is prescribed.

Cortexin has a complex of low molecular weight polypeptide fractions that penetrate the GEB to the nerve cells. It has nootropic, neuroprotective, antioxidant and tissue-specific effects.

And also:

• improves the work of the brain, learning and memory processes, concentration of attention, stability under stress;
• protects neurons from damage, reduces the toxicity of psychotropic drugs;
• has anticonvulsant and cerebroprotective properties;
• helps to quickly restore the functions of the CNS after stress.

products Advantages and disadvantages of

The advantage of Cortexin is its rapid effect on the brain, since the active substance of this drug acts directly on the brain cells. The agent does not have a lot of side effects in comparison with other similar drugs. It is recommended for children from the moment of birth, to pregnant and lactating mothers. Very inexpensive means for the price.

The disadvantages are:

• painful injections, but if you replace water with novocaine, the injections will not be so terrible, especially for children;
• is not produced in the form of tablets and capsules, so if you can not make an injection, you need to look for cortexin analogues in tablets.

Two firms-two prices

Cortexin is produced only in the form of a sterile lyophilized powder from which a solution for intramuscular injections is prepared. For adult patients, the powder is packed 10 mg in a vial, and for children, 5 mg each.

Diluted powder with water for injection or novocaine, because the injection is very painful and for children this is a big minus.

The drug is produced only in Russia by two pharmacological companies: Gerofarm Ltd. - it was the first to start the release of the product and its drug costs more than the second manufacturer - Samson.

According to the patients, the drug from the first manufacturer is considered reliable. Their composition is the same and the form of release, too. Differ in price, but not essential.

How can I replace the drug?

There are no analogues in the structural composition of the drug, but there are a number of drugs similar to it in the mechanism of action. TOP-15 analogues of Cortexin, which are available in both tablets and ampoules:

1. Aminolone - comes in the form of tablets, its active substance is gamma-aminobutyric acid.
2. Actovegin - is produced in the form of solutions for intravenous and intramuscular administration and tablets. The active substance is an extract from the blood of calves, released from protein.
3. Glycine - is produced in the form of sublingual tablets. The active substance is microencapsulated glycine.
4. Lucetam is a tablet and solution for intravenous and intramuscular injections. The active substance is piracetam.
5. Nootropil - is produced in the form of tablets and capsules, as well as in the form of a solution for oral administration and for intravenous and intramuscular administration. The active substance is piracetam.
6. Pantogam - available in the form of tablets and syrup. The active substance is the calcium salt of gopantenic acid.
7. Piracetam - is produced in the form of tablets and capsules, as well as a solution for injections. The active substance is piracetam.
8. Mexidol - is produced only in the form of tablets with the active substance - ethyl methylhydroxypyridine succinate.
9. Tonotene - is a tablet for resorption, is a homeopathic remedy. In its composition - antibodies to the brain-specific protein S-100 in large dilution.
10. Tenoten for children - tablets having an active substance - a protein, an antibody, specifically interacting with the S-100 protein, which is contained in the human nervous tissue.
11. Fenotropil - a pill with an active substance - phenotropil.
12. Ceraxon - is produced in the form of a solution for internal use and injections, both intramuscular and intravenous. Active substance: citicoline sodium.
13. Cerebrolysin is a solution for injections of various sizes. The active substance is a complex of peptides from the brain of a pig.
14. Encephabol - is produced in the form of tablets and a suspension for oral administration. The active ingredient is pyrithinol dihydrochloride monohydrate.
15. Nicomakes is a solution for injections. The active substance is ethylmethylhydroxypyridine succinate.

There are other drugs that produce a similar effect to Cortexin on the patient's brain, but these analogues are cheaper( almost all) and no less effective.

Comparative characteristics of

We compared Cortexin and its most popular analogues-competitors and that's what they got.

On comparison Cerebrolysin

Both drugs are nootropic and possess neuroprotective action. Cerebrolysin also has neurotrophic activity - it is the ability to replace the function of deceased brain cells.

Both drugs restore the functions of cerebral circulation, are used after traumatic brain injuries, and with mental retardation in children.

Cerebrolysin is used for strokes, spinal cord injuries, for the therapy of endogenous depression, autism, enuresis.

Cortexin is used when memory and thinking worsen, encephalopathy, epilepsy, encephalitis, cerebral palsy in newborns, with delayed speech and motor development and poor learning ability of children. Both drugs are used to treat the autistic spectrum in children from the first year of life.

Simultaneous use of Cortexin and Cerebrolysin in cardiology restores the basic parameters of the heart. With ischemic stroke, both drugs work in the same way, reducing the number of deaths.

If the speech development is delayed, both agents act the same, but Cortexin has a side effect - excitation of the child. Both drugs can not be used in pregnancy and lactation, as they can cause allergy, Cerebrolysin in turn can not be with epilepsy and with kidney failure.

For the price of Cortexin is cheaper than Cerebrolysin in 2 times, therefore at their identical properties the preference is given to the first.

Cortexin VS Actovegin

Both preparations refer to nootropics, the active substance of which is of animal origin. They have similar indications for use, but with Actovegin, another drug of nootropic series is prescribed.

Cortexin treats discirculatory encephalopathy well, and Actovegin helps with this pathology only in conjunction with other medications.

Cortexin remains the only remedy in the treatment of neonates with CNS injuries, which gives a positive result. Chronic fatigue syndrome is eliminated faster with Cortexin.

Both agents cause allergies, but are well combined with other medicines.

Cortexin is contraindicated in pregnancy and lactation and Actovegin is a little cheaper.

Mexidol - popular, but is it good?

Both drugs have similar indications for use:

• encephalopathy;
• memory impairment and thinking;
• decreased learning ability;
• diffuse.

Both have a powerful neuroprotective effect and regulate the content of dopamine in the brain. They are well used in complex treatment of craniocerebral trauma( they give a qualitative and rapid result), as well as with ischemic brain lesions.

This treatment is prescribed by a doctor and it is carried out strictly under his supervision. Mexidol and Cortexin can not be used in pregnancy, breast-feeding, acute kidney failure, and the first drug can not be used even in acute liver failure.

For the price they are approximately the same.

Ceraxon - what's in the title you mine?

Both are nootropic agents, but with different active substances. Ceraxon is more effective than Cortexin for removing cerebral edema, so, after its application, memory or attention is quickly restored.

It can be used both in the acute period of the disease, and during the rehabilitation period.

Cerexon has more contraindications - they can not be treated by children from birth.

And also a short duration of treatment.

The price of Ceraxon is also high in comparison with Cortexin.

Compatibility with other drugs

Cortexin with other drugs interacts slightly. Therefore, it is used in the complex treatment of many diseases. Information on the adverse consequences in this case was not.

All complex appointments are performed by a doctor and supervise the treatment process. The drug is appointed on the recommendation of the treating doctor, whether to apply its analogues, too, he decides. It is necessary to fulfill all its purposes and not engage in self-medication.