Ketorolac: detailed instructions with explanations and feedback

Ketorolac belongs to the group of non-steroidal anti-inflammatory drugs that are used in cases of severe pain caused by the onset of inflammation or injury.

Use this medication only with the advice of a doctor and in accordance with the instructions given.

Form release

Ketorolac is offered by manufacturers in two forms of release:

• round tablets coated with a thin film shell containing 10 mg of active substance;
• solution for intravenous or intramuscular injection slightly yellowish color, where the active substance is contained up to 30 mg per 1 ml of the formulation.

The drug is used in the treatment of quite a large number of complex and dangerous diseases that cause human pain and suffering, as Ketorolac has the following effects on the human body:

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• has analgesic effect - relieves pain;
• The anti-inflammatory effect of makes it possible to use this drug in the treatment of various diseases that are associated with damage and inflammation of soft tissues;
• renders a weak antipyretic action.

Because of its chemical composition, this remedy is used only for the doctor's prescription, because it has many contraindications and side effects, which will be discussed later.

Pharmacokinetics of the drug

The drug has excellent absorption in the organs of the gastrointestinal tract, which makes this form of consumption quite popular.

The bioavailability of the components in this case reaches approximately 80-100%.After 40 minutes, its effect on the body is noted, when the content of components in the blood increases.

Intramuscular or intravenous administration of the drug provides 100% bioavailability. The content of the constituent components in the blood reaches the oral dose in 20 minutes after the administration of the drug.

Medication components

The drug consists of tromethamine ketorolac, which is contained in an amount of 10 mg per 1 tablet or 30 mg per 1 ml of intravenous or intramuscular solution.

The excipients include:

• microcrystalline cellulose;
• magnesium stearate;
• talc;
• crospovidone;
• lactose monohydrate;
• sodium chloride;
• disodium edetate.

Excipients help the main component to be better absorbed and absorbed into the blood.

Mechanism of action

Immediately after ingestion or administration of the drug, the enzymes COX-1 and COX-2 perform nonselective inhibited activity in peripheral tissues, which leads to a slowing of the biosynthesis of the modulators of pain sensitivity and inflammation.

In its effects, ketorolac can not be attributed to drugs that are addictive and involve a large number of side effects.

Thanks to active excipients, the described drug can be set on one level with morphine( but only comparing the analgesic force) and other potent non-steroidal anti-inflammatory drugs.

Indications for use

Ketorolac is recommended for use in the following situations:

1. In the postoperative period , when the pain syndrome has not yet passed and worries a person. Here you can identify gynecological, cavitary, urological and orthopedic operations. In most cases, it is used intravenously or intramuscularly.
2. When an is injured, a fracture, a dislocation, an extension. Depending on the nature of the injury, a tablet or solution for intramuscular injection is used.
3. During the onset of , neuralgic pain , manifestations of osteochondrosis or osteoarthritis. The form of release of the drug and the regimen also depends on the degree and nature of the disease.
4. Oncological diseases , when the patient suffers from a severe pain syndrome.
5. During the onset of toothache or after dental intervention.
6. Various pains in the back or muscles .

Ketorolac is allowed to be used as an anesthetic, but taking into account the indications for use.

Therefore, if there is a pain syndrome, you should consult a specialist to find out the cause of discomfort.

Contraindications and restrictions

The drug is prohibited for use in cases of patient:

• in the presence of diseases of the respiratory system;
• in case of individual intolerance to acetylsalicylic acid;
• of individual intolerance to other constituents and pyrazolone series;
• in case of bleeding diagnosis;
• for the diagnosis of hyperglycemia;
• in cases of confirmed intestinal inflammation;
• for diseases of the gastrointestinal tract, especially at the stage of exacerbation;
• for renal and hepatic insufficiency, as well as for liver and kidney diseases;
• in case of a stroke;
• during pregnancy and after childbirth;
• is not authorized for use in the treatment of children younger than 16 years of age;
• in a previously diagnosed hemorrhagic diathesis.

Do not use if the person has chronic pain.

The drug is to be used only after consulting a doctor, because it contains a large number of contraindications.

Instruction for use

Compliance with the instructions for use is extremely important when using such potent drugs as Ketorolac.

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Here should follow the doctor's prescription so as not to harm yourself even more .

Depending on the nature of the disease, the doctor recommends a certain form of application of the drug.

Assign dosage to professional

The dosage of the drug is prescribed only by a specialist after a thorough and thorough examination to determine the cause of the pain syndrome.

Drug dosage:

1. The use of tablets occurs once and is subsequently repeated depending on the pain syndrome. The daily dose should not exceed 40 mg for adults( 4 tablets).
2. The use of the intramuscular and intravenous solution of depends on the age of the patients and their general condition. Adults and children over 16 years of age can apply Ketorolac 10 to 60 mg at the first administration and up to 30 mg every 6 hours or depending on the severity of the disease( if pain occurs).Patients over 65 years of age take the drug up to 15 mg every 4 to 6 hours. The same dosage is intended for people of all ages with a violation of the normal functioning of the kidneys.

Before use, it is necessary to adjust the scheme of administration and use of the medicine with the attending physician. Otherwise, there is a high probability of side effects.

Overdose and side effects of

The drug has quite dangerous side effects, which can occur due to non-compliance with the dosage and general rules of drug use, which include:

• disrupting the kidneys;
• nausea and vomiting;
• is also an erosive-ulcerative lesion of the gastrointestinal tract.

This is important!

Special instructions include the observance of the rules for taking the drug and its compatibility with other non-steroidal anti-inflammatory drugs.

Complex treatment can lead to fluid retention and increased blood pressure, it is often found violations of the cardiovascular activity.

The medicine can not be combined with alcohol - the likelihood of side effects and complications is high.

It is not recommended to use Ketorolac in the presence of diseases of the kidneys and liver, as well as in violation of the functioning functions of the of these organs.

Interaction with other drugs directly depends on the general condition of the patient, so you should not use the medication yourself if you already have other medicines in addition to it.

Do not use the drug to women during pregnancy and lactation. It is forbidden to admit children under 16 years old.

Compliance with all the mentioned rules and regulations will help to avoid problems with the use of the product.

Practical experience of using

Reviews of patients and doctors who practice the use of Ketorolac for the treatment of their patients.

To date, medicine is not known for so many drugs that would be effective in the postoperative period.

Ketorolac is used constantly, because it does not have a detrimental effect on the body, but follow the contraindications nevertheless follows.

Nadezhda Kurbatova, surgeon

Several months ago I broke my leg at work. At first I did not even understand that something terrible had happened. Only it hurt my leg. The partner offered me Ketorolac.

Saw him from pains in the back. I was helped, the pain subsided, but not for long. Fracture after all. When the leg was already plastered in the emergency room, the doctors also advised taking the first days of Ketorolac. There already was no censure.

Igor Prokofiev, 41, Surgut

I recently had appendicitis cut out. I will only say that the sensations after the operation are terrible! The suture, all stomach or belly hurts, is more shortly a nightmare! The doctors gave me injections of Ketorolac.

I will not say anything negative - the drug worked. If you have an injection in the morning, then you can walk peacefully until the evening. Even when getting out of bed, there were no strong pains.

Violetta Zhdanova, 24, Moscow

Of all the statements, it can be concluded that taking Ketorolac should be only in connection with the need and according to the instructions.

Voluntary use without consulting a doctor can lead to serious consequences.

Purchase and storage of medication

Price of Ketorolac:

• tablets from 25 to 35 rubles;
• solution from 50 to 70 rubles.

Tablets and solution are stored at a temperature of 15 to 25 degrees Celsius in a place inaccessible to children.

Shelf life of tablets - 3 years, solution - 2 years. It is released in pharmacies only on prescription from a doctor.

If funds are not available at the pharmacy. ..

In such cases, analogues of Ketorolac can be used:

• Ketanov;
• Adolor;
• Dolak;
• Ketalgin;
• Dolomin.

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