Blood Test for HPV in women, men, children. Causes of HPV infection

Analysis of blood for the presence of HPV is the primary diagnostic method which allows to determine the presence or absence of a pathogenic microorganism in human tissues.

What is HPV and its species

Papillomavirus - is the pathogen that is parasitic in the blood, epithelial tissue and nerve endings person. It appears in the form of benign tumors, which have externally the form of round, flat and genital warts. There are over 170 strains of papillomaviruses, which have the ability to mutate, changing its genotype.

Isolated following pathogens:

• alfapapillomavirus;
• betapapillomavirus;
• gammapapillomavirus;
• mupapillomavirus;
• nupapillomavirus.

Currently, WHO has information on 600 different genotypes of HPV that have been identified in human patients undergoing examination.

There are confirmed by scientific evidence, that 40 pathogen strains are localized exclusively in the epithelial tissues intimal area in the mucosa of the urethra, vagina, cervix, inside the bladder, the anus and the inside circumferential line intestine.

The remaining strains of HPV are able to induce the formation of warts in any other body part. In most cases, they appear directly in the places where there was penetration of the microorganism in the damaged epithelial tissue.

Some papilloma harmless, as a benign tumor. Other genotypes, mutated under the influence of negative factors are transformed into malignant tumors. May become a cause of cervical cancer, skin, mammary gland.

How and under what conditions appears papillomavirus

Analysis venous blood papillomavirus shows the presence or absence of a pathogenic microorganism in the patient's tissues. It appears pathogen viral infection only after its penetration will occur in the human body. At the expiration of the incubation period, which can last from 15 days to several years, the patient's blood detected antibodies to papillomavirus.

The activity of the infectious agent and its manifestation in the body of the carrier is directly dependent on how strong is the immune system. People with weak immune function, which recently had an infectious or inflammatory disease, HPV is shown more clearly.

As part of the blood can be detected not only antibodies to pathogens, but there are outward signs of the disease. Body warts begin to form, shape, color, location, and size of which depends on the genotype of the virus.

symptoms of HPV

The presence of HPV in the human body shows signs that are characteristic of this skin disease.

Distinguish the following symptoms of a pathogenic activity of the pathogen:

• appear flat or rounded warts on the skin surface of the finger, which indicates infection with epithelium at the time of touching the upper limbs infected object;
• extraneous growths as warts are found under the breasts, in the armpit, in the abdomen, back and other parts of the body;
• on the skin surface of the foreskin in men, labia in women in a circle anus, on the inside of the thigh, there are pointed warts that affect tissue only intimate zone (active papillomavirus genotype transmitted sexually solely as a result of unprotected sexual contact).

The above symptoms are the main feature of the human body papillomavirus infection. The disease is characterized by a high degree of latency. The patient does not experience sickness, decline of physical strength, fever or intoxication.

Within a short period of time a person can be infected simultaneously by several strains of HPV, but will not even be aware of it.

The reasons for increased rates

A blood test for HPV is carried out if there are signs of an emerging papillomatosis.

It is a dermatological condition that can result from the following reasons:

• sexual contact with a carrier papillomavirus, which occurs without the use of barrier contraception (the most common cause of transmission of the pathogen);
• HPV infection of the newborn child at the time of its passage through the birth canal if the mother attended the infectious agent;
• visiting public swimming pools, toilets, showers, saunas, on the surface of objects which are viable papillomavirus virions;
• household way of infection, when the penetration of parasitic microorganism occurs at the moment of touch damaged area of ​​skin to viral infection source (shaking hands, door handles, handrails, money, sports equipment in gymnasium);
• autoinfection during brushing of teeth, to shave hairs on the skin surface.

To prevent infection of human papillomavirus is sufficient to avoid the above risk factors. During examination by a dermatologist patient asks relevant questions relating to his lifestyle. whether he visits public baths, gymnasiums, swimming pools, it has one or more sexual partners, whether contraceptive uses.

Indications for study on HPV

A blood test for HPV is performed in the biochemical laboratory of a public hospital or in a part of the clinic. It is recommended to consult your health care provider and pass a comprehensive examination on HPV if published the following symptoms of the disease:

• genital warts, which appeared in the armpits, under the breasts, around the neck, on the inside of the thighs;
• warts that are found on the skin surface of the genital organs, is presented in a single or plural;
• Male or female recently have sexual contact with a partner unstable and thus do not use barrier contraception;
• on the surface of the fingers, stomach, back, began to appear around the warts;
• on the bottom portion legs formed nodal seal which outwardly resemble corns, but can be seen by visual inspection of the presence of the rod (the root plantar papilloma).

The development of HPV in the body of an infected person can be accompanied by a decrease in the overall immunity. Not exclude the presence of concomitant diseases as SARS and the common cold. The sudden appearance of benign tumors on the body should be the main indication for taking a blood test for HPV.

How to determine the HPV

A blood test for HPV is the most reliable and accurate view of the research, which allows you to determine the presence of virions parasitic microorganism in human tissues.

In medical practice, the following methods of diagnosis of HPV:

• clinical examination - the doctor performs a visual inspection of the area of ​​the body where there was a proliferation of benign neoplasms of disease history, determines the color shade of warts, genital warts, their potential tendency to carcinogenicity;
• colposcopy cervical mucosa to prevent HPV infection of the body (carried by treatment of fabrics with a special solution);
• cytology smears collected from the surface of the mucous membrane of the vagina and the cervix to highlight atypical cells;
• histological examination of selected warts epithelial tissue samples, as well as the cervix to determine the strain of HPV and confirmation of their benign nature of origin;
• analysis of venous blood using the polymerase chain reaction (PCR), which is the direction in experimental molecular biology and DNA fragments of the virus is allowed to select (if the results of the study are available, then the person is not HPV infected);
• screening test, in the course of which the patient's blood samples are analyzed to determine the most HPV strains human as well as an analysis as to their carcinogenicity, used in most developed countries and is conducted with simultaneous diagnostics cervix).

In the case of a patient the presence of genital warts, except of venous blood analysis, women require medical examination gynecologist, and men examination urologist. This is necessary in order to timely detect the spread of warts on the mucous membrane of the vagina, cervix, urethra, bladder wall.

Preparation and analysis on HPV

Carrying out the venous blood test for HPV - it is not difficult type of diagnostic examination, which requires a minimum number of preparatory activities.

Before visiting the lab and delivery of the biological material for research requires the following steps:

• 24 hours before the diagnosis excluding fat diet, smoked, pickled food, the presence of which is capable of loading the liver and indirectly affect the biochemical composition of the blood;
• the day before the analysis is not to expose the body in heavy physical loads, to avoid over-voltage and psycho-emotional stress;
• 48 hours before the analysis is not to drink alcohol;
• Blood HPV rent in the morning of day in the period from 08-00 to 10-00 hours, so before leaving the laboratory must be necessarily a good breakfast;
• smoking before delivery of the analysis is contraindicated;
• 15 min. up sampling of venous blood is not allowed to drink 200 ml of water.

For qualitative analysis of HPV and obtain the most reliable data it is recommended to perform the above-mentioned rules of preparation for laboratory diagnostics. To study it requires 10-15 ml of biological material. Immediately after the sampling of venous blood is recommended to drink hot tea with sugar or eat.

Decoding on the papillomavirus test results

Decryption process blood test results has been dermatologist or oncologist, on a survey in which the patient is.

In conclusion laboratory information may be read as follows:

• fragments of HPV DNA is detected - this indicates that the patient is completely healthy, and virions parasitic microorganism in its tissues are not available;
• less than 3 Lg level - points to the low concentrations of viral infection in the blood and epithelial tissues, infection occurred recently or the immune cells successfully resist disease;
• 3 to 5 Lg - clinically significant indicators suggesting that the disease is in an acute form of flow, the appearance of new warts and warts;
• over 5 Lg - a very high level of concentration of HPV in the blood, indicating strong weakening of the immune system, as well as the rapid spread of viral infection throughout the body.

  

With the above data, each person can independently decode the results of their laboratory research on HPV levels. In this case, visit the dermatologist and his advice is a prerequisite for effective treatment and recovery in the future.

If any results of the analysis should seek medical attention

Appeal to an infectious diseases doctor or a dermatologist is a must after a positive result for the presence of HPV in the blood. Even if the number of virions parasitic microorganisms is low. The absence of adequate response can lead to the development of complications and adverse effects on the health of the patient.

Methods of treatment of papillomavirus

HPV therapy is based on managing the consequences of the disease in the form of warts, and is strengthening the patient's immune system.

Medications

In the treatment of papillomavirus pharmacy medicines are used means that destroy the wart formed on the body, as well as stimulate immune cells to the inhibition of HPV, namely:

• ointment Papillon - is applied to the surface of the warts and warts 1-2 times a day for 15 days, and medication costs 75 rubles. 30 g of a tube;
• Papiloks spray - a liquid solution, which is treated skin benign neoplasms 2 times a day until complete disappearance of (price preparation RUB 400.);
• tincture of Echinacea purpurea - a natural immunostimulant, which take 20 drops 3 times a day for 8 weeks (the cost of medications 30 rubles. a bottle with capacity 50 ml).

In people with a strong immune system, HPV can be destroyed by the body on its own without the use of drugs. Remove only have the consequences of the disease in the form of warts and genital warts.

Traditional methods

There are traditional treatments of HPV, which can be used at home, applying the following recipes:

• juice of celandine - need daily to pluck the young plant shoots and wiped his warts yellow juice as long as papillomas are completely gone;
• wiping potatoes - cut the vegetable in half, brush with warts his flesh, and then bury it in the ground, saying: "As soon as the rot the potatoes, and all my warts disappear "(after 3 weeks of benign tumors on the body leaving themselves a);
• mixture to enhance immunity - need to squeeze the juice of 4 lemons, add the 100 grams of honey and aloe leaf 3, which pre killed in slurry (all components are thoroughly mixed and the resultant means take 1 tbsp. l. 3 times a day for 15 minutes. before meals for 15 days).

Before HPV treatment with folk remedies treatment, you must first consult a dermatologist or an infectious disease specialist who discovered papillomatosis.

Other methods

In addition to medication therapy and traditional medicine recipes, the following ways of dealing with HPV can be applied:

• Electrocoagulation - removal of warts current;
• cryosurgery - destruction papillomas solution of liquid nitrogen;
• Laser photocoagulation - a laser burning warts;
• surgical removal - neoplasm excision is performed with a scalpel;
• chemical burn - to affect wart solutions of acids or alkalis.

All of the above methods of treatment prescribed by a doctor, dermatologist and performed by a qualified technician. Self therapy can lead to thermal and chemical burns of healthy skin.

possible complications

Ignoring the disease, the lack of proper control and measures to remove extraneous growths, as well as strengthen the immune system, can lead to the following complications:

• cervical cancer;
• proliferation warts inside the urethra;
• HPV transmission to children during birth;
• appearance plural number of papillomas in various areas of the body;
• the formation of a large number of warts on the external and internal genital organs, making it impossible to maintain an active sex life;
• degeneration benign cancer formation in a further skin cancer lesion.

To prevent the development of complications listed above, you need to periodically take the analysis of venous blood papillomavirus, and in case of confirmation of a positive result, immediately begin a comprehensive treatment.

In this case, the forecast of a full recovery is favorable and risk-free transition of the disease into a chronic form with a further relapse. Papillomatosis - this is not a dangerous disease, which must be kept under control.

Registration of the article: Mila Friedan

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