Eosinophilic cationic protein is elevated in a child by an adult. Norma, what it means, what to do

Increased concentration of eosinophil cationic protein is an indication of such pathologies organism as bronchial asthma, dermatitis atopic type, allergies to food, fur farming and pets, household dust, spores of fungal microorganisms, flower pollen.

Increased percentage of eosinophil cationic protein in people who are prone to the occurrence of allergic rhinitis.

What is a cationic protein, and its norm for the body

Eosinophilic cationic protein can be elevated in the presence of the respective diseases. The medical records indicated under the code ERC.

This is a basic marker of eosinophils. PSA is an enzyme which in its composition and functions of such a body reminiscent of ribonuclease digestion, the pancreas.

It is released into serum as a result of contact with the molecules of the potential allergen immunoglobulins. In addition, eosinophilic protein has been actively involved in the neutralization of irritants that penetrate into individual organism with food, drink, air or in contact with skin surface.

ECP is able to stimulate activity of lymphocytes, which provides a more powerful and extensive immune response directed at suppressing the pathogenic activity of allergens.

That is why the protein compound of this type is considered by physicians as a physiological identifier to track dynamic progression of allergic disease, to determine the patient's health improvement or worsening of the current symptoms.

In the treatment of allergies of all types of blood donation in the eosinophilic cationic protein is a prerequisite.

Norma index cationic protein

The concentration of the protein compound is proportionate in relation to the number of eosinophils that are in the blood. Below is detailed information on ESG standards for healthy people as well as with various kinds of diseases.

norm	Health status
7 g / l	It is typical for the person who has no signs of an allergic reaction. Completely absent acute immune response to external or internal stimulus lymphocytes.
From 15 to 20 g / l	This kind of performance to occur in patients suffering from allergic asthma natural origin, which are periodically transferred in the acute stage, which is expressed bouts asphyxiation.
From 60 to 70 g / l	Diagnosed patients infected with invasive species helminth infections (eg, from the family of Schistosoma) when venous blood is oversaturated parasitic life forms.
About 200 g / l	Typical for patients with hypereosinophilic syndrome, which is extremely rare.

Determining the concentration of ECP is an important step in the diagnosis of diseases of allergic origin. Establishment of eosinophil protein standards applicable in the field of pulmonology, parasitology, dermatology, as well as the presence of autoimmune diseases.

The reasons for improving cationic protein

Eosinophilic cationic protein is elevated in the presence of pathological processes in the human body.

Most often splash ECP occurs in people who have co-morbidities, such as:

• allergic rhinitis natural origin, which arises as a result of contact with the nasal mucous membrane irritant potential (seasonal manifestation can vary or be constant);
• extensive body insemination helminth eggs and larvae;
• in acute gastroenteritis, eosinophilic esophagitis type colitis;
• bronchial asthma, which has developed as a complication of an existing allergy;
• intolerance to certain types of food (milk, strawberries, citrus fruit, cereals containing gluten);

  

• acute inflammatory process, developed in the larynx, triggered by bacterial or viral infection;
• Accommodation in environments with high humidity levels where common molds and their spores;
• presence of benign and malignant tumors in the paranasal sinuses (polyps, carcinomas);
• hypereosinophilic syndrome;
• atopic dermatitis type;
• prolonged therapy drugs containing in its composition minocycline, penicillin, phenobarbital, co-trimoxazole.

Increasing the level of ECP can be triggered by long-term use of NSAIDs. In case of a sharp spike concentration eosinophil cationic protein, it is necessary to stop taking drugs as well be screened for the presence of the above diseases.

Symptoms improving cationic protein

Eosinophilic cationic protein increased only in those clinical situations where there are already signs associated underlying disease.

The man in the serum is too high concentration of ECP, experiencing the following symptoms:

• skin surface is constantly itchy, characterized by increased dryness, redness, sensitivity to sunlight, contact with synthetic clothing, there is a tendency to the appearance of dermatitis;
• allergic rhinitis, sneezing long, recurring nasal congestion, headache (all these symptoms were amplified after interaction with a potential allergen);
• emergent asthma attacks lead to bronchial spasm or edema, laryngeal mucosa;
• ulcer formation in the oral cavity, where the bacterial flora is within normal limits, and sores on the mucosa occur, as the effects of an allergic reaction;
• disorder of the digestive system, which occurs immediately after the reception of certain kinds of food (begins bloating, nausea, vomiting, rumbling stomach stops, reduced bowel motility, diarrhea begins, present pain in the center of the abdomen);
• violation of the rhythmic activity of the heart, dizziness, shortness of breath, sudden decrease or increase in blood pressure (usually in patients with diagnosed resistant hypotension).

Depending on what triggered the increase of ECP above-listed symptoms is saturated to a greater or lesser extent. Because of the increase in diffuse clinical picture of eosinophilic cationic protein can be confused with other diseases.

Diagnosis of the level of cationic protein

Eosinophilic cationic protein increased or within the normal range is able to identify only a comprehensive survey of the whole organism. cause of violations ECP standards are also set. Once a patient comes to the doctor, performed its initial examination, listen to complaints, set the current symptoms.

After this, one must pass the following tests:

• checking for the presence of fecal helminth eggs and larvae;
• general study of capillary blood;
• removing leukocyte;
• sputum fence, released during coughing, with further laboratory analysis on the microflora;
• study of venous blood to the bot;
• general urine analysis;
• screening isolation of immunoglobulins, which are active against such potential allergens as epithelial fibers cats, rabbits, dogs, dust mites, pollen of birch, alder, poplar fluff, hair, disputes molds.

In that case, if the results of a survey of venous blood or stool, the patient showed signs the presence of parasites, it shows the passage of ultrasound examination of the abdominal cavity. The latter type of instrumental diagnosis is needed to determine the localization of worms for their quick and efficient removal in the future.

diagnostic confidence

It is important to remember that the results of laboratory studies can be distorted if the patient receives medicinal preparations containing acetylsalicylic acid in their composition or doxycycline. In such situations, there is an increase level of ECP that is not associated with the current disease.

Prevention enhance cationic protein

Eosinophilic cationic protein is elevated in people who do not take preventive measures aimed at preventing the development of diseases that increase the concentration of the enzyme.

To ECP level was within the normal range, you must observe the following rules:

• before eating to wash hands thoroughly with warm soapy water;
• not to eat dirty fruit and vegetables;
• avoid bathing ponds or undrained dirty water;
• timely treat bacterial and viral infections of the nasopharynx;
• avoid polyposis, nasal sinuses, and in the case of foreign growths, to take measures for their removal;
• not to consume foods that are not perceived by the digestive system and cause an allergic reaction;
• translate flow chronic pulmonary inflammatory disease, bronchitis;
• in the rooms of the house or apartment wet cleaning regularly to avoid accumulation of dust;
• if you are allergic to wool, it is necessary to avoid prolonged contact with pets, down.

In the summer and spring, when the air increases the concentration of allergens in the form of pollen, poplar fluff should regularly take antihistamines. Appointment of drug, dosage and duration of therapy is determined by the doctor. Unauthorized treatment can aggravate health.

To which the doctor ask

Elevated levels of ECP - it is not always a sign of a severe allergic reaction. To establish the true cause high concentrations of eosinophil cationic protein in serum, you need to use the data and conclusions instrumental examination of laboratory blood tests, stool, urine.

To do this, the patient can turn to professionals such as an allergist, internist, dermatologist, a pulmonologist. Treatment of children engaged pediatrician. Initially encouraged to attend specialized professionals given the presence of symptoms.

Therapies enhance cationic protein

Reducing elevated levels of ECP is possible only in case of successful treatment of the underlying disease, caused severe immune response.

conservative therapies may be used in the treatment process, which provides the use of pharmacy medicines, folk remedies, as well as immunization method, if the patient has a tendency to allergies. Listed below are the most effective ways to reduce eosinophil cationic protein.

drug therapy

Use of drugs needed for treating a disease that causes the release of ECP in blood composition. Type medicines used depends on the diagnosed disease.

In the process of reducing eosinophil cationic protein following drug therapy can be used:

• Aleron - is taken for the relief of allergic reaction (the recommended dosage - 1 tablet per day, which is drunk at the same time, but treatment is not more than 1 month.)
• suprastin - drink 2-3 tablets per day until complete disappearance of the allergic symptoms, and thus reduce the level of ECP (Maximum daily dose of 4 tablets, and the average duration of administration of the drug for 2-3 weeks);
• L-CET - you must take 1 tablet daily at the same time without chewing (a course of therapy is 1-2 weeks, be prescribed with care for people with impaired renal function);
• Vermoxum - a drug that reduces eosinophil protein that is elevated as a result of invasion helminths (Take 1 tablet in the morning and evening for 3 days, and after 2 weeks of therapy repeated);
• pyrantel - treatment consists of taking a single dose of 1, which is calculated as follows: a child older than 6 years old drink 1 tablet per 20 kg weight, adult with a body weight less than 75 kg - 3 tablets over said weight - 4 tablets (after 2 weeks Curative repeat).

In most cases, the cause of elevated ECP is a severe allergic reaction or helminth invasion, so to reduce the concentration of eosinophil cationic protein used above drugs.

If the violation of the norms ECP triggered inflammation in the nose and throat, the doctor sets a strain of infectious agent disease and selects medicines, the basic components of which are able to suppress the activity of bacterial or viral microorganisms specific species.

Traditional methods

Furthermore pharmacy drugs allows stabilize eosinophil cationic protein, there are folk recipes which have similar properties, namely:

• take 1 hour. l. Dried sage, pour into a vacuum flask, and then add 0.5 liters of boiling water and close the container, leaving it stand for 1.5 h (take 2 hours. l. 3 times a day for 30 minutes. before meals, course of treatment - 10 days);
• collect 3 tbsp. l. partitions from walnuts, pour 500 ml of vodka or brew, put for 7 days in a dark and cool place, and then taking 50 ml, 2 times daily before meals (treatment days 7-10);
• Take 1 hour. l. Dried leaves tansy, minced root and gorchavki chamomile, herbs emptied into a metal container, to fill in 1 liter of running water, and then boiled at low heat for 15 minutes. (Prepared decoction taking 100 ml 3 times a day for 20 minutes. before a meal, and duration of treatment is from 10 to 14 days);
• It needs to take 1 tbsp. l. flax seed, grind them in a coffee grinder to a powder state, pour into a thermos or any other container, which holds heat well, and then add 0.5 liters of boiling water (150 mL take 3 times a day for 30 min. before meals for 7 days);
• collect 300 g of pumpkin seeds dehulled, grind them to a state of slurry by using a meat grinder, add 150 ml of cold boiled water and the resulting mixture was taken 3 times a day for 1 st. l. 15 min. before meals for 15 days.

Before you start self-treatment increased the level of ECP, you must pass a comprehensive examination of the body, identify the cause of the disease and consult a specialized physician. This will avoid potential complications and deterioration of health.

operative intervention

Another method of therapy aimed at stabilizing level eosinophil cationic protein is operative intervention to removal of benign or malignant tumor growing in the paranasal axils.

It is used in the event that it is the cause of increased ECP was established on the results of the survey. The operation is performed under local or general anesthesia. It lasts no longer than 30-40 minutes. The rehabilitation period is 5-8 days

Vaccination

An alternative method of treatment is the immunization of a patient. To prevent a severe allergic reaction, a person prone to immune response to potential allergens in advance being vaccinated.

This is a standard procedure for vaccination, when injected into the body small doses of a particular type of stimulus in the blood serum gradually develop antibodies, and immune system no longer responds to extensive inflammation with the release of a large number of eosinophilic cationic protein.

complications

The presence of elevated levels of ECP fraught with irregularities in the internal organs and body support systems. There are the following possible complications and adverse effects that can cause high eosinophilic cationic protein concentration:

• disorders of the digestive functions, poor absorption of vitamins, minerals and other nutrients arriving with food;
• aggravation of the allergic reaction when it begins with rhinitis, and proceeds in asthma with frequent cramps airway;
• deterioration of health of the skin and scalp, the appearance of excessive dryness epithelium, formation of wounds, fractures;
• frustration of a chair, which is expressed in frequent constipation or diarrhea;
• inability to enjoy a full social life, as a broad immune response stimulated by elevated levels of ECP, will cause rhinitis, cough, not the perception of the body of certain foods that are potential allergens (milk, eggs, cheese, citrus fruits, fish, nuts, honey).

The most dangerous complication of increased eosinophil cationic protein is a lightning-fast swelling of the mucous membrane of the larynx, in which the patient loses the opportunity to breathe normally.

Such a reaction of the organism is possible, if the patient is not engaged in the treatment of allergies, I did not take measures to reduction of ECP, which resulted in the occurrence of anaphylactic shock and onset of lethal outcome.

Registration of the article: Vladimir the Great

Video of eosinophils

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