GGT in the biochemical analysis of blood increased. What does it mean, the rate for women, men and children by age, treatment

Increased GGT in the biochemical composition of the blood may be indicative of such dangerous liver diseases such as cirrhosis, hepatitis, intoxication or viral etiology. Increased GGT standards common in people who for several days, weeks and months of abuse strong alcohol.

What is GGT

GGT (gamma-glutamyl) in the biochemical composition of the blood - a protein enzyme which indicates the increase of the disease state of the liver or gallbladder tissues. It is in the cells of internal organs contains a digestive enzyme.

By their physiological destination GGT is a biochemical substance which, together with bile accelerates the process of fat splitting, entering the body as part of food.

In healthy people, who do not have associated liver disease or gall bladder, gamma-glutamyl in the bloodstream is completely absent, or its level is low.

If a person is suffering from pathologies of these bodies, then there is a destruction of the cells, resulting in a fall in blood GGT molecule.

After the biochemical blood tests revealed an increased concentration of protein enzyme, which indicates the necessity of organizing a more thorough examination of the patient.

Indications for analysis

To the physician made the decision on the need for biochemical analysis of blood at the level of gamma-glutamyl, you must have the following circumstances:

• Preparations are performed prior to surgery (in this case the patient delivers a detailed biochemical analysis of blood, as a result of which the figures stand out GGT);
• required to conduct selection of liver tissue in order to perform histological analysis or other methods of investigation;
• the patient complains of muscle weakness, constant fatigue, lack of appetite, bitter taste in the mouth, pain in the right hypochondrium;
• skin and whites of the eyes acquired a deep yellow shade;
• in the patient is currently undergoing treatment of liver disease, pancreatic or gall bladder;
• there was a full lightening of stool, diarrhea predominant, and there are desires in a toilet for 1.5-2 hours. after eating the food;
• nausea, vomitus and selection aversion to fried and fatty foods;
• change the color tone of urine with natural yellow to dark brown, which also points to the death of liver cells;
• It does not stop itching, and other symptoms of dermatological diseases are absent;
• patient already has associated disease as hepatitis, sclerosing cholangitis, cirrhosis or liver neoplastic lesion tissues;
• over a long period of time a person is abusing liquor, or else passes therapy alcohol dependence (preparation of analysis performed before treatment to determine the extent of tissue affected liver).

GGT in the biochemical composition of the blood increased in cases where there are also gall bladder dysfunction. Therefore patients suffering from diseases of the body, as shown renting assay on gamma-glutamyl transpeptidase in the bloodstream.

How to prepare for blood donation

To obtain the most reliable data without distorting the results of the analysis, it is necessary to observe the rules of preparation for blood donation. they are as the following actions on the part of the person who will undergo laboratory examination:

• over the last 12 hours before the delivery of biological material does not eat food (allowed to drink only water, but in small quantities);
• 2 days prior to blood donation eliminate physical stress associated with running on a short and long distance, weight lifting, sit-ups, involvement of the muscles of the abdominal cavity;
• 24 hours before the test to prevent psycho-emotional overstrain, stress and conflict situations (people must be in a favorable environment, surrounded by relatives and friendly people);
• in the last 30 minutes. before blood sampling does not smoke, and do not take medications that contain in its structure nicotine (especially true for men and women who are trying to get rid of the addiction and the use of substitution means therapy);
• 5 days prior to delivery of the analysis is not drinking alcohol, since alcohol is able to provoke massive death of liver cells and, therefore, the blood will get an excess amount of GGT enzyme.

At all stages of preparation for the donation of blood for its biochemical research on gamma-glutamyl, recommended excluded from the diet smoked, fat, pickled foods, so as not to create an increased load on the liver tissue.

person Menu passing examination should consist of grains of cereals, vegetables, milk products, boiled potatoes and lean meats (chicken, turkey, rabbit, veal).

How is the analysis on the GGT

GGT in the biochemical composition of the blood increased or retained its normal levels, determines the detailed laboratory study.

It held as follows:

• biochemistry laboratory technician runs a fence of venous blood from the vessel, which is located in elbow region (for analysis will require from 10 to 20 ml of biological material);
• the patient receives a treatment of wound surface of the skin at the site of puncture;
• the collected blood is sent to the sterile laboratory conditions for analysis;
• in determining the level of gamma-glutamyl transpeptidase in the bloodstream, used chemicals reagents that allow the enzyme protein isolate of this type, as well as automatic analyzers medical equipment;
• completion of diagnostic laboratory receives exhaustive information about the biochemical composition of blood and the level of GGT.

The average duration of the study is from 1 to 2 hours. The availability of modern electronic devices and laboratory equipment accelerates the process of analysis.

If there is the slightest suspicion of a distortion of the survey doctor may take a second sampling of biological material with a concentration of GGT release. The measurement is made in units with respect to 1 L of venous blood.

Norma GGT in the analysis of blood biochemistry

Indicators of gamma-glutamyl as part of the bloodstream depends on the age of the patient under examination, as well as their gender. Below is a detailed table which displays rules enzyme protein for patients of the age categories.

Age and sex	Performance standards (no longer referred U / L values)
A child born 5 days ago	185
From 5 days to 6 months.	204
From 6 to 12 months.	34
From 1 to 3 years	18
From 3 to 6 years	23
From 6 to 12 years	17
The youth from 12 to 17 years	45
Girl teenager from 12 to 17 years	33
Male 18 years of age or older	From 10 to 71
Women 18 years and older	From 6 to 42

GGT in the biochemical composition of the blood are elevated in adults and young children who have severe damage to liver tissue, gallbladder and its ducts.

After receiving the results of laboratory studies, which indicated the excess concentration of a given protein enzyme PCP assigns a patient passing additional internal diagnostics above authorities.

Reasons for the increase of GGT in the blood

There are many diseases and factors whose presence triggers increased concentration of gamma-glutamyl transpeptidase. they all entail damage to the cell structure of liver tissue, pancreas, gallbladder wall, stomach, namely:

• biliary obstruction channels, which has arisen due to the development of jaundice mechanical type;
• Tumor formation in the stomach wall, which compresses the gallbladder and its ducts, disrupting their normal operation;

  

• chronic alcoholism (after complete rejection of liquor GGT increased concentration in the blood stream may persist for 1 month, while 30% of surveyed enzyme protein excretion occurred 3 times faster);
• gallstones and channels;
• surgical intervention on the liver, stomach, gallbladder, pancreas;
• sclerosing cholangitis type, and biliary cirrhosis (it does not matter what factors influence provoked massive death of liver cells);
• infectious mononucleosis flowing in complicated form (liver and spleen are involved in the inflammatory process, caused by a viral organism, so there is an increase in the volume of the said bodies, as well as damage to their tissue);
• Cancer tumor in the pancreas head;
• acute or chronic hepatitis type having Intoxication (exposure to chemicals toxic etiology), alcoholic or viral origin (this pathology characterized by the highest rates of GGT, as well as abrupt surge alkaline compounds phosphatase);
• pancreatitis caused by alcohol poisoning, or else acquired over a lifetime due to the negative impact of other factors;
• chronic heart failure;
• lupus erythematosus (dangerous systemic disease, which in the course of the development of human immune system starts to produce specific antibodies against its own tissues of the internal organs);
• hyperthyroidism thyroid, when it starts to synthesize a larger amount of hormone disruptive liver;
• cancer of the lung or breast glandular tissue, which had spread to the liver metastasis;
• myocardial infarction (GGT level surge occurs 3-4 days after suffering a seizure, as due to cardiac dysfunction increases the load on the liver);
• diabetes.

GGT in the biochemical composition of the blood increased to as long as the doctor did not conduct examination of the patient, do not establish the true cause of a high concentration of enzyme and protein not take steps to reduce the level of gamma-glutamyl.

Timely initiation of treatment Disease Detection allows you to stop further destruction of liver cells and cause biochemical composition of the blood in normal limits.

Is it dangerous for the life of GGT increase?

Increased concentration of gamma-glutamyl blood is not dangerous to health and life. The threat comes from diseases which are boosted level of the enzyme protein. Most of the pathologies listed in the section above, and can lead to long-term disorder of the digestive and endocrine systems.

In addition, no treatment of diseases such as hepatitis, cirrhosis, pancreatitis, cancer processes in tissues stomach, liver, pancreas, gall bladder and ducts, can lead to fatal attack outcome.

Methods for lowering GGT levels in the blood

It should be understood that increasing the concentration of gamma-glutamyl blood - is not a disease, but one of the many symptoms suggestive of underlying pathology. Therefore, to reduce GGT recommended as primary therapy can begin disease faster.

If there is an urgent need to reduce the saturation of the enzyme protein, the This effect can be achieved by administering these medicaments:

• Acetylsalicylic acid;
• Paracetamol;
• Vitamin C.

The dosage and duration of therapy is determined individually, based on the clinical picture of the disease. In most cases, no need to take drugs that reduce the concentration of GGT in the blood. Enough to begin treatment of disease that caused massive death of liver cells to within 1-3 days biochemical indicators of the blood returned to normal.

Reducing GGT folk remedies

Alternative medicine offers the alternative methods of reducing liver enzyme concentrations. For these purposes, herbal teas and tinctures of medicinal plants. Below are some folk recipes that can improve the function of the liver, gall bladder and pancreas, stop the destruction of their cells:

• 5 dig roots dandelion, wash them under running water. Finely cut with a knife, pour into a metal container and then pour 1.5 liters of boiling water (container covered with a lid and left for infusion for 1 h). After cooling, the mass is taken for 250 g of 2 times a day for 15 minutes. before meals. Duration of treatment 5-7 days;
• take 2 tbsp. l. dried astragalus plant and pour them into the pan, then pour 1 liter of tap water, put on a gas stove where the boil for 15 minutes. (Prepared decoction is drunk from 100 g 3 times a day for 10 minutes. before the meal with a treatment duration of 10-12 days);
• pour into a metal container 3 tbsp. l. Dried hips, pour them 2 liters of water and boil to simmer for 20 minutes, and upon completion of the cooking process to use as a conventional compote in unlimited quantities (the broth has a natural diuretic and choleretic properties, and promotes cell regeneration liver);
• take 15 g of dried milk thistle plants, fill it with 1 liter of boiling water, wrap container thick woolen cloth or towel, giving the possibility to infuse medication for 10 min for 2 hours (assuming 150 ml in the morning and evening until meal).

Before you attempt to independently reduce the concentration of GGT in the blood with the help of traditional medicine, we recommend that you visit a therapist, get tested, and only with his permission to start treatment healing plants.

What is the reason lowering GGT rules

gamma-glutamyl concentration may not only be increased but reduced.

Such a change in the biochemical composition of the blood in the following cases:

• hypothyroidism - a disease in which the presence of low thyroid tissue, which entails a hormonal imbalance;
• extreme obesity;
• continuously taking phenobarbital or ascorbic acid;
• oncologic bone disease;
• state of pregnancy;
• chronic renal failure.

Special increase the level of GGT in the biochemical composition of the blood is required. Before the patient and the physician seeks to treat the underlying disease, getting rid of that It will restore the normal function of the liver and other internal organs involved in the process digestion.

Registration of the article: Mila Friedan

Video of GGT in the blood

Elena Malysheva tell about the rate and causes of deviations of GGT: